pentylenetetrazole has been researched along with Aqueductal Stenosis in 3 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Knockdown of lgi1a results in a seizure-like hyperactivity phenotype with associated developmental abnormalities characterized by cellular loss in the eyes and brain." | 1.37 | Loss of zebrafish lgi1b leads to hydrocephalus and sensitization to pentylenetetrazol induced seizure-like behavior. ( Cowell, JK; Kozlowski, DJ; Mumm, JS; Saxena, M; Teng, Y; Walker, S; Xie, X, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Teng, Y | 1 |
| Xie, X | 1 |
| Walker, S | 1 |
| Saxena, M | 1 |
| Kozlowski, DJ | 1 |
| Mumm, JS | 1 |
| Cowell, JK | 1 |
| Abed, WT | 1 |
| Alavijeh, MS | 1 |
| Bayston, R | 1 |
| Shorvon, SD | 1 |
| Patsalos, PN | 1 |
| Földi, M | 1 |
| Obál, F | 1 |
| Kahán, A | 1 |
| Wagner, A | 1 |
| Csanda, E | 1 |
| Börcsök, E | 1 |
1 trial available for pentylenetetrazole and Aqueductal Stenosis
| Article | Year |
|---|---|
[Lymphogenous encephalopathy: a new clinical picture and its management].
Topics: Adult; Animals; Brain Diseases; Cerebrospinal Fluid; Cerebrovascular Circulation; Child; Clinical Tr | 1967 |
2 other studies available for pentylenetetrazole and Aqueductal Stenosis
| Article | Year |
|---|---|
Loss of zebrafish lgi1b leads to hydrocephalus and sensitization to pentylenetetrazol induced seizure-like behavior.
Topics: Amino Acid Sequence; Animals; Apoptosis; Behavior, Animal; Brain; Gene Expression Regulation, Develo | 2011 |
An evaluation of the epileptogenic properties of a rifampicin/clindamycin-impregnated shunt catheter.
Topics: Animals; Clindamycin; Epilepsy; Hydrocephalus; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; | 1994 |