pentylenetetrazole has been researched along with Apnea in 6 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Apnea: A transient absence of spontaneous respiration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The primary cause of seizure-induced death for all mice was apnea, as (1) apnea began during a seizure and continued for tens of minutes until terminal asystole, and (2) death was prevented by mechanical ventilation." | 8.02 | Postictal Death Is Associated with Tonic Phase Apnea in a Mouse Model of Sudden Unexpected Death in Epilepsy. ( Blizzard, EA; Goodkin, HP; Meisler, MH; Panchal, PS; Patel, MK; Richerson, GB; Saraf, P; Teran, FA; Wagley, PK; Wagnon, JL; Wengert, ER; Wenker, IC, 2021) |
| " In this study, we investigated the basic mechanism of aminophylline [theophylline-2-ethylenediamine]-induced convulsions and the effects of Brewer's yeast-induced pyrexia in mice." | 7.75 | Effect of Brewer's yeast-induced pyrexia on aminophylline-elicited convulsions in mice. ( Araki, H; Kawasaki, H; Ochi, R; Suemaru, K, 2009) |
| "The primary cause of seizure-induced death for all mice was apnea, as (1) apnea began during a seizure and continued for tens of minutes until terminal asystole, and (2) death was prevented by mechanical ventilation." | 4.02 | Postictal Death Is Associated with Tonic Phase Apnea in a Mouse Model of Sudden Unexpected Death in Epilepsy. ( Blizzard, EA; Goodkin, HP; Meisler, MH; Panchal, PS; Patel, MK; Richerson, GB; Saraf, P; Teran, FA; Wagley, PK; Wagnon, JL; Wengert, ER; Wenker, IC, 2021) |
| " In this study, we investigated the basic mechanism of aminophylline [theophylline-2-ethylenediamine]-induced convulsions and the effects of Brewer's yeast-induced pyrexia in mice." | 3.75 | Effect of Brewer's yeast-induced pyrexia on aminophylline-elicited convulsions in mice. ( Araki, H; Kawasaki, H; Ochi, R; Suemaru, K, 2009) |
| "During seizures an increase of K+e occurred subsequent to the electrical discharges, while during postictal depression of EEG normal levels of K+e were measured." | 1.26 | EEG and extracelluar K+ in rat brain during pentylenetetrazol seizures and during respiratory arrest. ( Astrup, J; Bolwig, TG; Christoffersen, GR, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Wenker, IC | 1 |
| Teran, FA | 1 |
| Wengert, ER | 1 |
| Wagley, PK | 1 |
| Panchal, PS | 1 |
| Blizzard, EA | 1 |
| Saraf, P | 1 |
| Wagnon, JL | 1 |
| Goodkin, HP | 1 |
| Meisler, MH | 1 |
| Richerson, GB | 1 |
| Patel, MK | 1 |
| Ochi, R | 1 |
| Suemaru, K | 1 |
| Kawasaki, H | 1 |
| Araki, H | 1 |
| WEBER, HD | 1 |
| LENDLE, L | 1 |
| Bolwig, TG | 1 |
| Astrup, J | 1 |
| Christoffersen, GR | 1 |
| Barkai, AI | 1 |
| Neki, JS | 1 |
| Kishore, B | 1 |
6 other studies available for pentylenetetrazole and Apnea
| Article | Year |
|---|---|
Postictal Death Is Associated with Tonic Phase Apnea in a Mouse Model of Sudden Unexpected Death in Epilepsy.
Topics: Animals; Apnea; Convulsants; Diaphragm; Electroencephalography; Electromyography; Epilepsy; Female; | 2021 |
Effect of Brewer's yeast-induced pyrexia on aminophylline-elicited convulsions in mice.
Topics: Aminophylline; Animals; Anticonvulsants; Apnea; Bronchodilator Agents; Child; Convulsants; Diazepam; | 2009 |
[CONDITIONS FOR THE TOXIC EFFECT OF HYDROGEN SULFIDE AND POSSIBILITIES OF TREATMENT IN ACUTE POISONING].
Topics: Antidotes; Apnea; Cell Respiration; Cyanides; Electrocardiography; Guinea Pigs; Hydrogen Sulfide; Pe | 1965 |
EEG and extracelluar K+ in rat brain during pentylenetetrazol seizures and during respiratory arrest.
Topics: Animals; Apnea; Brain; Electroencephalography; Extracellular Space; Male; Pentylenetetrazole; Potass | 1977 |
Combined electroconvulsive and drug therapy.
Topics: Anesthesia; Apnea; Atropine; Bipolar Disorder; Combined Modality Therapy; Depressive Disorder; Elect | 1985 |
Narcostimulation in depressive states.
Topics: Accidents; Amnesia; Anesthesia; Apnea; Central Nervous System; Convulsive Therapy; Depression; Elect | 1968 |