pentylenetetrazole has been researched along with Amnesia-Memory Loss in 28 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study we examined the effect of post-training administered calcium channel blockers nifedipine (10 and 40 mg/kg) and diltiazem (10 and 30 mg/kg) on amnesia induced by PTZ kindling in shuttle-box- and step-down-trained rats." | 7.71 | Effect of the calcium channel blockers nifedipine and diltiazem on pentylenetetrazole kindling-provoked amnesia in rats. ( Genkova-Papazova, MG; Lazarova-Bakarova, M; Petkova, B; Shishkova, N, 2001) |
| "The effect of adenosine agents on amnesia induced by pentylenetetrazole was examined in mice." | 7.71 | Effects of adenosine receptor agonists and antagonists on pentylenetetrazole-induced amnesia. ( Homayoun, H; Khavandgar, S; Zarrindast, MR, 2001) |
| "The effect of the intracerebroventricular (ICV) administration of taurine on amnesia, convulsions and death caused by hypoxia was investigated in mice." | 7.67 | Effect of ICV taurine on the impairment of learning, convulsions and death caused by hypoxia. ( Bartolini, A; Bennardini, F; Franconi, F; Ghelardini, C; Giotti, A; Malcangio, M; Malmberg-Aiello, P, 1989) |
| " Cycloheximide, which antagonizes the puromycin-induced amnesia 3 hours after training, also antagonizes the puromycin effect on susceptibility to seizure." | 7.64 | Puromycin effect on memory may be due to occult seizures. ( Barondes, SH; Cohen, HD, 1967) |
| " Active compounds exhibited an inverted U-shaped dose-response curve." | 5.27 | Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam. ( Butler, DE; L'Italien, YJ; Marriott, JG; Nordin, IC; Poschel, PH; Zweisler, L, 1984) |
| " In the present study we examined the effect of post-training administered calcium channel blockers nifedipine (10 and 40 mg/kg) and diltiazem (10 and 30 mg/kg) on amnesia induced by PTZ kindling in shuttle-box- and step-down-trained rats." | 3.71 | Effect of the calcium channel blockers nifedipine and diltiazem on pentylenetetrazole kindling-provoked amnesia in rats. ( Genkova-Papazova, MG; Lazarova-Bakarova, M; Petkova, B; Shishkova, N, 2001) |
| "The effect of adenosine agents on amnesia induced by pentylenetetrazole was examined in mice." | 3.71 | Effects of adenosine receptor agonists and antagonists on pentylenetetrazole-induced amnesia. ( Homayoun, H; Khavandgar, S; Zarrindast, MR, 2001) |
| "The effect of the intracerebroventricular (ICV) administration of taurine on amnesia, convulsions and death caused by hypoxia was investigated in mice." | 3.67 | Effect of ICV taurine on the impairment of learning, convulsions and death caused by hypoxia. ( Bartolini, A; Bennardini, F; Franconi, F; Ghelardini, C; Giotti, A; Malcangio, M; Malmberg-Aiello, P, 1989) |
| " Cycloheximide, which antagonizes the puromycin-induced amnesia 3 hours after training, also antagonizes the puromycin effect on susceptibility to seizure." | 3.64 | Puromycin effect on memory may be due to occult seizures. ( Barondes, SH; Cohen, HD, 1967) |
| " Active compounds exhibited an inverted U-shaped dose-response curve." | 1.27 | Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam. ( Butler, DE; L'Italien, YJ; Marriott, JG; Nordin, IC; Poschel, PH; Zweisler, L, 1984) |
| "The data suggest that overt convulsions may be necessary for the development of pentylenetetrazol-induced retrograde amnesia." | 1.26 | Pentylenetetrazol-induced amnesia: a case for overt seizures. ( Albala, B; Palfai, T, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (75.00) | 18.7374 |
| 1990's | 2 (7.14) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Butler, DE | 1 |
| Nordin, IC | 1 |
| L'Italien, YJ | 1 |
| Zweisler, L | 1 |
| Poschel, PH | 1 |
| Marriott, JG | 1 |
| Nkwingwa, BK | 1 |
| Wado, EK | 1 |
| Foyet, HS | 1 |
| Bouvourne, P | 1 |
| Jugha, VT | 1 |
| Mambou, AHMY | 1 |
| Bila, RB | 1 |
| Taiwe, GS | 1 |
| Godinho, M | 1 |
| Ribeiro, AM | 1 |
| Fernandes, VS | 1 |
| Barbosa, FF | 1 |
| Nascimento, EB | 1 |
| Munguba, H | 1 |
| Silva, RH | 1 |
| ASCHENBACH, EH | 1 |
| PEARLMAN, CA | 1 |
| SHARPLESS, SK | 1 |
| JARVIK, ME | 1 |
| JERVIS, G | 1 |
| SERGIO, C | 1 |
| Cohen, HD | 1 |
| Barondes, SH | 1 |
| Oscós-Alvarado, A | 1 |
| Martínez de Muñoz, D | 1 |
| Martin, JR | 1 |
| Schoch, P | 1 |
| Jenck, F | 1 |
| Moreau, JL | 1 |
| Haefely, WE | 1 |
| Genkova-Papazova, MG | 3 |
| Lazarova-Bakarova, MB | 1 |
| Petkova, B | 2 |
| Shishkova, N | 2 |
| Lazarova-Bakarova, M | 2 |
| Homayoun, H | 1 |
| Khavandgar, S | 1 |
| Zarrindast, MR | 1 |
| Banerjee, U | 2 |
| Das, P | 2 |
| Bookin, HB | 2 |
| Pfeifer, WD | 2 |
| Iuvone, PM | 1 |
| Boast, CA | 1 |
| Gray, HE | 1 |
| Dunn, AJ | 1 |
| Palfai, T | 3 |
| Albala, B | 1 |
| Malcangio, M | 1 |
| Bartolini, A | 1 |
| Ghelardini, C | 1 |
| Bennardini, F | 1 |
| Malmberg-Aiello, P | 1 |
| Franconi, F | 1 |
| Giotti, A | 1 |
| Weissman, A | 1 |
| van Buskirk, R | 1 |
| McGaugh, JL | 1 |
| Kurtz, P | 1 |
| Neki, JS | 1 |
| Kishore, B | 1 |
| Ahlers, RH | 1 |
| Best, PJ | 1 |
| Vinitskiĭ, IM | 1 |
| Abuladze, GV | 1 |
| Chillag, D | 1 |
| Nieschulz, O | 1 |
1 review available for pentylenetetrazole and Amnesia-Memory Loss
| Article | Year |
|---|---|
Drugs and retrograde amnesia.
Topics: Amnesia; Anesthesia, General; Animals; Anticonvulsants; Azaguanine; Barbiturates; Behavior, Animal; | 1967 |
27 other studies available for pentylenetetrazole and Amnesia-Memory Loss
| Article | Year |
|---|---|
Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam.
Topics: Amnesia; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Huma | 1984 |
Ameliorative effects of Albizia adianthifolia aqueous extract against pentylenetetrazole-induced epilepsy and associated memory loss in mice: Role of GABAergic, antioxidant defense and anti-inflammatory systems.
Topics: Albizzia; Amnesia; Animals; Anti-Inflammatory Agents; Anticonvulsants; Antioxidants; Epilepsy; gamma | 2023 |
A rodent model of appetitive discrimination with concomitant evaluation of anxiety-like behavior.
Topics: Amnesia; Animals; Anti-Anxiety Agents; Anxiety; Appetitive Behavior; Diazepam; Discrimination Learni | 2009 |
The use of metrazol in non-institutionalized elderly patients.
Topics: Aged; Amnesia; Disease; Humans; Patients; Pentylenetetrazole | 1956 |
Retrograde amnesia produced by anesthetic and convulsant agents.
Topics: Amnesia; Amnesia, Retrograde; Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthetics; Convulsa | 1961 |
[PERMANENT DEFICIENCY OF FIXATION MEMORY AFTER UNILATERAL TEMPORAL LOBECTOMY IN AN EPILEPTIC SUBJECT].
Topics: Amnesia; Bemegride; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Cloni | 1964 |
Puromycin effect on memory may be due to occult seizures.
Topics: Amnesia; Animals; Behavior, Animal; Brain; Cycloheximide; Drug Antagonism; Humans; Memory; Mice; Ner | 1967 |
Effects of 4-hydroxy, 4-phenyl, caproamide on pentylenetetrazol-induced amnesia.
Topics: Amides; Amnesia; Animals; Anticonvulsants; Avoidance Learning; Humans; Male; Mice; Pentylenetetrazol | 1981 |
Pharmacological characterization of benzodiazepine receptor ligands with intrinsic efficacies ranging from high to zero.
Topics: Acoustic Stimulation; Amnesia; Animals; Anticonvulsants; Conditioning, Operant; Eating; Female; Flum | 1993 |
Piracetam and fipexide prevent PTZ-kindling-provoked amnesia in rats.
Topics: Amnesia; Animals; Avoidance Learning; Kindling, Neurologic; Male; Pentylenetetrazole; Piperazines; P | 1996 |
The GABA-B antagonist CGP 36742 prevent PTZ-kindling-provoked amnesia in rats.
Topics: Amnesia; Animals; Avoidance Learning; Epilepsy; GABA Antagonists; Kindling, Neurologic; Male; Organo | 2000 |
Effect of the calcium channel blockers nifedipine and diltiazem on pentylenetetrazole kindling-provoked amnesia in rats.
Topics: Amnesia; Animals; Avoidance Learning; Calcium Channel Blockers; Convulsants; Diltiazem; Kindling, Ne | 2001 |
Effects of adenosine receptor agonists and antagonists on pentylenetetrazole-induced amnesia.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amnesia; Analysis of Variance; Animals; Avoidance Lear | 2001 |
Comparative study of retrograde amnesia in rats on active and passive avoidance tasks and spontaneous recovery of memory.
Topics: Amnesia; Amnesia, Retrograde; Animals; Avoidance Learning; Electroshock; Ether; Female; Humans; Male | 1977 |
Effect of lysine vasopressin on pentylenetetrazol-induced retrograde amnesia in rats.
Topics: Amnesia; Amnesia, Retrograde; Animals; Avoidance Learning; Humans; Lypressin; Male; Memory; Pentylen | 1977 |
Pentylenetetrazol: inhibitory avoidance behavior, brain seizure activity, and [3H]lysine incorporation into brain proteins of different mouse strains.
Topics: Amnesia; Animals; Avoidance Learning; Brain; Cerebral Cortex; Electroencephalography; Hippocampus; H | 1977 |
Vasopressin antagonizes retrograde amnesia in rats following electroconvulsive shock.
Topics: Amnesia; Amnesia, Retrograde; Animals; Carbon Dioxide; Electroshock; Humans; Lypressin; Male; Memory | 1978 |
Pentylenetetrazol-induced amnesia: a case for overt seizures.
Topics: Amnesia; Amnesia, Retrograde; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Humans; | 1976 |
Variable temporal gradients of retrograde amnesia: contingency on tasks and species.
Topics: Amnesia; Amnesia, Retrograde; Animals; Avoidance Learning; Electroshock; Escape Reaction; Female; Hu | 1976 |
Effect of ICV taurine on the impairment of learning, convulsions and death caused by hypoxia.
Topics: Amnesia; Animals; Anticonvulsants; Avoidance Learning; Hypoxia; Injections, Intraventricular; Learni | 1989 |
Pentylenetetrazol-induced retrograde amnesia and brain seizures in mice.
Topics: Amnesia; Animals; Avoidance Learning; Cerebral Cortex; Dose-Response Relationship, Drug; Electrodes, | 1974 |
State-dependent learning produced by Metrazol.
Topics: Amnesia; Animals; Avoidance Learning; Discrimination Learning; Exploratory Behavior; Housing, Animal | 1973 |
Narcostimulation in depressive states.
Topics: Accidents; Amnesia; Anesthesia; Apnea; Central Nervous System; Convulsive Therapy; Depression; Elect | 1968 |
Retrograde amnesia for discriminated taste aversions: a memory deficit.
Topics: Amnesia; Animals; Apomorphine; Association; Avoidance Learning; Conditioning, Psychological; Discrim | 1972 |
[Retrograde amnesia induced by corazole against a background of anesthesia].
Topics: Amnesia; Anesthesia, General; Animals; Conditioning, Classical; Escape Reaction; Ethyl Ethers; Human | 1971 |
Time-dependent memory deficits produced by pentylene-tetrazol (Metrazol)--the effect of reinforcement magnitude.
Topics: Amnesia; Animals; Avoidance Learning; Conditioning, Psychological; Electroshock; Female; Humans; Mal | 1971 |
[Experimental retrograde amnesias in mice].
Topics: Amnesia; Animals; Behavior, Animal; Brain Injuries; Humans; Mice; Pentylenetetrazole; Seizures | 1967 |