Page last updated: 2024-11-08

pentylenetetrazole and Allodynia

pentylenetetrazole has been researched along with Allodynia in 6 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Research Excerpts

ExcerptRelevanceReference
"Adenosine was administered daily, 30 min before PTZ or vehicle."1.34Systemic administration of adenosine ameliorates pentylenetetrazol-induced chemical kindling and secondary behavioural and biochemical changes in mice. ( Akula, KK; Dhir, A; Kulkarni, SK, 2007)
"Naproxen was administered daily 45 min before PTZ or vehicle."1.33Effect of naproxen, a non-selective cyclo-oxygenase inhibitor, on pentylenetetrazol-induced kindling in mice. ( Dhir, A; Kulkarni, SK; Naidu, PS, 2005)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Khan, FA1
Ali, G2
Rahman, K1
Khan, Y1
Ayaz, M1
Mosa, OF1
Nawaz, A1
Hassan, SSU1
Bungau, S1
Akbar, S1
Subhan, F1
Karim, N1
Shahid, M1
Ahmad, N1
Mahmood, W1
Fawad, K1
Guerrini, G1
Ciciani, G1
Bruni, F1
Selleri, S1
Martini, C1
Daniele, S1
Ghelardini, C1
Di Cesare Mannelli, L1
Costanzo, A1
Petrillo, P1
Angelici, O1
Bingham, S1
Ficalora, G1
Garnier, M1
Zaratin, PF1
Petrone, G1
Pozzi, O1
Sbacchi, M1
Stean, TO1
Upton, N1
Dondio, GM1
Scheideler, MA1
Dhir, A2
Naidu, PS1
Kulkarni, SK2
Akula, KK1

Other Studies

6 other studies available for pentylenetetrazole and Allodynia

ArticleYear
Efficacy of 2-Hydroxyflavanone in Rodent Models of Pain and Inflammation: Involvement of Opioidergic and GABAergic Anti-Nociceptive Mechanisms.
    Molecules (Basel, Switzerland), 2022, Aug-25, Volume: 27, Issue:17

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Cisplatin; Disease Models, Animal; Edema; Flavanones;

2022
6-Methoxyflavanone attenuates mechanical allodynia and vulvodynia in the streptozotocin-induced diabetic neuropathic pain.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Amines; Animals; Computer Simulation; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Fl

2016
Development of ligands at γ-aminobutyrric acid type A (GABAA) receptor subtype as new agents for pain relief.
    Bioorganic & medicinal chemistry, 2011, Dec-15, Volume: 19, Issue:24

    Topics: Animals; Anti-Anxiety Agents; Cattle; Hyperalgesia; Male; Mice; Pain; Pentylenetetrazole; Radioligan

2011
Evidence for a selective role of the delta-opioid agonist [8R-(4bS*,8aalpha,8abeta, 12bbeta)]7,10-Dimethyl-1-methoxy-11-(2-methylpropyl)oxycarbonyl 5,6,7,8,12,12b-hexahydro-(9H)-4,8-methanobenzofuro[3,2-e]pyrrolo[2,3-g]isoquinoline hydrochloride (SB-23586
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:3

    Topics: Animals; Binding, Competitive; Carrageenan; Cells, Cultured; Convulsants; Cyclic AMP; Electroshock;

2003
Effect of naproxen, a non-selective cyclo-oxygenase inhibitor, on pentylenetetrazol-induced kindling in mice.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:7

    Topics: Animals; Behavior, Animal; Brain; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Femal

2005
Systemic administration of adenosine ameliorates pentylenetetrazol-induced chemical kindling and secondary behavioural and biochemical changes in mice.
    Fundamental & clinical pharmacology, 2007, Volume: 21, Issue:6

    Topics: Adenosine; Adenosine Deaminase; Animals; Anticonvulsants; Behavior, Animal; Hyperalgesia; Hypothalam

2007