pentylenetetrazole has been researched along with Acute Liver Injury, Drug-Induced in 5 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The activity of these compounds on seizure control is independent of histone deacetylase inhibitory activity (associated with the teratogenicity of VPA), and does not correlate with liver cell toxicity." | 1.39 | Seizure control by ketogenic diet-associated medium chain fatty acids. ( Chang, P; Chen, PE; Plant, N; Terbach, N; Walker, MC; Williams, RS, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Warner, DJ | 1 |
| Chen, H | 1 |
| Cantin, LD | 1 |
| Kenna, JG | 1 |
| Stahl, S | 1 |
| Walker, CL | 1 |
| Noeske, T | 1 |
| Abdel-Dayem, MA | 1 |
| Elmarakby, AA | 1 |
| Abdel-Aziz, AA | 1 |
| Pye, C | 1 |
| Said, SA | 2 |
| El-Mowafy, AM | 1 |
| El-Agamy, DS | 1 |
| Chang, P | 1 |
| Terbach, N | 1 |
| Plant, N | 1 |
| Chen, PE | 1 |
| Walker, MC | 1 |
| Williams, RS | 1 |
| FISCHER, A | 1 |
| TAKACS, L | 1 |
| VARGA, I | 1 |
5 other studies available for pentylenetetrazole and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Valproate-induced liver injury: modulation by the omega-3 fatty acid DHA proposes a novel anticonvulsant regimen.
Topics: Administration, Oral; Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Docosahexaen | 2014 |
Prevention of sodium valproate-induced hepatotoxicity by curcumin, rosiglitazone and N-acetylcysteine in rats.
Topics: Acetylcysteine; Animals; Anticonvulsants; Body Weight; Chemical and Drug Induced Liver Injury; Convu | 2010 |
Seizure control by ketogenic diet-associated medium chain fatty acids.
Topics: Animals; Anticonvulsants; Caprylates; Cell Line; Chemical and Drug Induced Liver Injury; Convulsants | 2013 |
[STUDY OF THE INTERMEDIATE METABOLISM OF DRUGS USING PARTIAL HEPATECTOMY].
Topics: Barbiturates; Caffeine; Chemical and Drug Induced Liver Injury; Chloralose; Hepatectomy; Hepatitis; | 1963 |