pentylenetetrazole has been researched along with Action Tremor in 16 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this investigation was to determine whether paraplegia induced by neoplastic cord compression affects the pharmacodynamics of phenobarbital general anesthesia or of pentylenetetrazol (PTZ)-induced convulsions." | 7.69 | Pharmacodynamics of phenobarbital anesthesia and pentylenetetrazol-induced maximal seizures in a rat model of neoplastic spinal cord compression. ( Alfon, J; Hoffman, A; Siegal, T, 1994) |
| "Fumitremorgin A (FTA), a neurotropic mycotoxin induced dose-dependent abnormal behaviors, including tremor, clonic convulsion, kangaroo posture and tonic extensor convulsion in the mouse." | 7.67 | Abnormal behavioral effects elicited by a neurotropic mycotoxin, fumitremorgin A in mice. ( Kikkawa, K; Suzuki, S; Yamazaki, M, 1984) |
| "The purpose of this investigation was to determine whether paraplegia induced by neoplastic cord compression affects the pharmacodynamics of phenobarbital general anesthesia or of pentylenetetrazol (PTZ)-induced convulsions." | 3.69 | Pharmacodynamics of phenobarbital anesthesia and pentylenetetrazol-induced maximal seizures in a rat model of neoplastic spinal cord compression. ( Alfon, J; Hoffman, A; Siegal, T, 1994) |
| "Experiments on male Wistar rats and Icr:Icl mice studied the influence of the novel compound--amino acid-containing 1,4-dihydropyridine derivative glutapyrone (G) on acute generalized seizures, arecoline and nicotine tremor, and 45Ca2+ uptake in brain synaptosomes." | 3.68 | [The anticonvulsant properties of glutapyrone--a new type of derivative of amino acid-containing 1,4-dihydropyridines]. ( Bisenieks, EA; Cebers, G; Duburs, GIa; Germane, SK; Karpova, MN; Klusa, VE; Pankov, OIu, 1993) |
| "Fumitremorgin A (FTA), a neurotropic mycotoxin induced dose-dependent abnormal behaviors, including tremor, clonic convulsion, kangaroo posture and tonic extensor convulsion in the mouse." | 3.67 | Abnormal behavioral effects elicited by a neurotropic mycotoxin, fumitremorgin A in mice. ( Kikkawa, K; Suzuki, S; Yamazaki, M, 1984) |
| "Pentylenetetrazole (75 mg/kg) induced a characteristic coarse body tremor (accompanied by limb extension) and hyperactivity in 4-day-old rat pups." | 3.67 | Diazepam reverses the effects of pentylenetetrazole in rat pups by acting at type 2 benzodiazepine receptors. ( Aranko, K; Dingemanse, J; File, SE; Johnston, AL, 1989) |
| "Cyclic GMP levels were dose-dependently increased by excitatory drugs such as picrotoxin, pentetrazol, oxotremorine and harmaline in mouse cerebellum and medial forebrain (parts of the cortex, hippocampus, hypothalamus, thalamus, striatum and midbrain) in vivo." | 3.65 | Effects of stimulatory and depressant drugs on cyclic guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate levels in mouse brain. ( Dinnedahl, V; Gumulka, SW; Opmeer, FA; Schönhöfer, PS, 1976) |
| " The Type I pyrethroid, cismethrin (15 mg/kg, po), produced a 17% reduction in the threshold dosage of ip-PTZ required to induce a seizure, while delaying the onset of generalized seizure activity." | 1.28 | An examination of the proconvulsant actions of pyrethroid insecticides using pentylenetetrazol and amygdala kindling seizure models. ( Acheson, SK; Crofton, KM; Gilbert, ME; Mack, CM, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (75.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| LESSIN, AW | 1 |
| LONG, RF | 1 |
| PARKES, MW | 1 |
| Chiu, CS | 1 |
| Brickley, S | 1 |
| Jensen, K | 1 |
| Southwell, A | 1 |
| Mckinney, S | 1 |
| Cull-Candy, S | 1 |
| Mody, I | 1 |
| Lester, HA | 1 |
| Suzuki, S | 1 |
| Kikkawa, K | 1 |
| Yamazaki, M | 1 |
| Cousse, H | 1 |
| Mouzin, G | 1 |
| Bonnaud, B | 1 |
| Charveron, M | 1 |
| Stenger, A | 1 |
| Morre, M | 1 |
| Lauressergues, H | 1 |
| Hoffman, A | 1 |
| Alfon, J | 1 |
| Siegal, T | 2 |
| Karpova, MN | 1 |
| Germane, SK | 1 |
| Cebers, G | 1 |
| Pankov, OIu | 1 |
| Klusa, VE | 1 |
| Duburs, GIa | 1 |
| Bisenieks, EA | 1 |
| Opmeer, FA | 1 |
| Gumulka, SW | 1 |
| Dinnedahl, V | 1 |
| Schönhöfer, PS | 1 |
| Berti, F | 1 |
| Bernareggi, V | 1 |
| Folco, GC | 1 |
| Fumagalli, R | 1 |
| Paoletti, R | 1 |
| Desmedt, LK | 1 |
| Niemegeers, CJ | 1 |
| Lewi, PJ | 1 |
| Janssen, PA | 1 |
| Gilbert, ME | 1 |
| Acheson, SK | 1 |
| Mack, CM | 1 |
| Crofton, KM | 1 |
| Johnston, AL | 1 |
| File, SE | 1 |
| Dingemanse, J | 1 |
| Aranko, K | 1 |
| Smythe, JW | 1 |
| Ryan, CL | 1 |
| Pappas, BA | 1 |
| Wolf, HH | 1 |
| Rollins, DE | 1 |
| Rowland, CR | 1 |
| Reigle, TG | 1 |
| Funcke, AB | 1 |
| van Beek, MC | 1 |
| van Hell, G | 1 |
| Lavy, UI | 1 |
| Timmerman, H | 1 |
| Zandberg, P | 1 |
| Baker, WW | 1 |
| Marcucci, F | 1 |
| Guaitani, A | 1 |
| Fanelli, R | 1 |
| Mussini, E | 1 |
| Garattini, S | 1 |
16 other studies available for pentylenetetrazole and Action Tremor
| Article | Year |
|---|---|
CENTRAL STIMULANT ACTIONS OF ALPHA-ALKYL SUBSTITUTED TRYPTAMINES IN MICE.
Topics: Body Temperature; Brain; Carboxy-Lyases; Central Nervous System Stimulants; Indoles; Injections, Int | 1965 |
GABA transporter deficiency causes tremor, ataxia, nervousness, and increased GABA-induced tonic conductance in cerebellum.
Topics: Animals; Anxiety; Ataxia; Behavior, Animal; Benzodiazepines; Body Temperature; Body Weight; Cerebell | 2005 |
Abnormal behavioral effects elicited by a neurotropic mycotoxin, fumitremorgin A in mice.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antiparkinson Agents; Antipsychotic Agents; Behavior, | 1984 |
[Phenothiazine carboxamides that have anticholinergic properties].
Topics: Animals; Behavior, Animal; Convulsants; Dogs; Mice; Nicotine; Parasympatholytics; Pentylenetetrazole | 1980 |
Pharmacodynamics of phenobarbital anesthesia and pentylenetetrazol-induced maximal seizures in a rat model of neoplastic spinal cord compression.
Topics: Anesthesia; Animals; Histiocytoma, Benign Fibrous; Male; Paraplegia; Pentylenetetrazole; Phenobarbit | 1994 |
[The anticonvulsant properties of glutapyrone--a new type of derivative of amino acid-containing 1,4-dihydropyridines].
Topics: Animals; Anticonvulsants; Arecoline; Calcium; Cerebral Cortex; Dihydropyridines; Drug Evaluation, Pr | 1993 |
Effects of stimulatory and depressant drugs on cyclic guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate levels in mouse brain.
Topics: Animals; Atropine; Brain; Brain Chemistry; Convulsants; Cyclic AMP; Cyclic GMP; Diazepam; Drug Inter | 1976 |
Prostaglandin E2 and cyclic nucleotides in rat convulsions and tremors.
Topics: Animals; Cerebellum; Cyclic AMP; Cyclic GMP; Male; Pentylenetetrazole; Prostaglandins E; Rats; Seizu | 1976 |
Antagonism of maximal metrazol seizures in rats and its relevance to an experimental classification of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Ataxia; Drug Evaluation, Preclinical; Female; Pentylenetetrazole; Posture; | 1976 |
An examination of the proconvulsant actions of pyrethroid insecticides using pentylenetetrazol and amygdala kindling seizure models.
Topics: Amygdala; Animals; Convulsants; Disease Models, Animal; Injections, Intraperitoneal; Injections, Int | 1990 |
Diazepam reverses the effects of pentylenetetrazole in rat pups by acting at type 2 benzodiazepine receptors.
Topics: Animals; Anticonvulsants; Brain; Diazepam; Dose-Response Relationship, Drug; Female; Male; Pentylene | 1989 |
A behavioral and electrocorticographic comparison of diazepam and pentylenetetrazol in rat pups.
Topics: Animals; Animals, Newborn; Diazepam; Electrodes, Implanted; Electrophysiology; Pentylenetetrazole; R | 1988 |
The importance of endogenous catecholamines in the activity of some CNS stimulants.
Topics: Amphetamine; Animals; Antidepressive Agents; Catecholamines; Central Nervous System; Ephedrine; Male | 1969 |
Cyheptamide. A pharmacological evaluation.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholic Intoxication; Animals; Anticonv | 1970 |
Excitatory responses following intracaudate injection of N-methyl-dl-aspartic acid.
Topics: Aggression; Animals; Arousal; Aspartic Acid; Carbachol; Cats; Caudate Nucleus; Humans; Male; Methyla | 1972 |
Metabolism and anticonvulsant activity of diazepam in guinea pigs.
Topics: Adipose Tissue; Animals; Anticonvulsants; Brain; Chromatography, Gas; Diazepam; Drug Antagonism; Gui | 1971 |