pentoxifylline has been researched along with Vascular Diseases in 26 studies
Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The methylxanthine derivative pentoxifylline, widely used in the treatment of vascular diseases, also has numerous immunological effects." | 5.09 | Suppressive effect of pentoxifylline on natural killer cell activity; experimental and clinical studies. ( Balogh, A; Mándi, Y; Nagy, Z; Ocsovszki, I; Sipka, R, 1999) |
| "Metformin has unique, intrinsic actions specifically at the level of terminal arterioles, which are completely independent of its antidiabetic effect." | 2.48 | Microvascular diseases: is a new era coming? ( Rapin, JR; Wiernsperger, N, 2012) |
| "Pentoxifylline (PTX) is a methylxanthine derivative with a variety of anti-inflammatory effects." | 2.44 | Pentoxifylline: a drug with wide spectrum applications in dermatology. ( Zargari, O, 2008) |
| "Pentoxifylline (PTX) is a phosphodiesterase inhibitor drug used to improve peripheral vascular disease." | 2.43 | [Pentoxifylline: a cheap substitute for anti-TNFalpha agents?]. ( Cathébras, P; Guy, C; Koenig, M; Rousset, H, 2006) |
| "Pentoxifylline has been used extensively to improve microcirculation, particularly in peripheral vascular disease." | 2.38 | "Stiff red cell syndrome". A review of the treatment of sickle cell disease with pentoxifylline. ( Ambrus, JL; Conway, J; Meky, NN; Reddington, TM, 1993) |
| " We investigated the effect of chronic administration (2 weeks) of imipramine (20 mg/kg/day) and pentoxifylline (50 mg/kg/day) on behavioral, aortic histological abnormalities, and level of circulating endothelial progenitor cells (CEPCs) in peripheral blood of male Wistar rats exposed to chronic mild stress (CMS) and high-fat diet." | 1.51 | Pentoxifylline ameliorates chronic stress/high-fat diet-induced vascular wall disease: the role of circulating endothelial progenitor cells. ( Abdel-Tawab, AM; Aboul-Fotouh, S; Farrag, KA; Habib, MZ; Labib, JMW; Mekawy, MAEA, 2019) |
| "Peripheral neuropathy, infection, and peripheral vascular disease can produce serious problems in diabetic patients, particularly in the lower limbs." | 1.28 | Lower limb problems in diabetic patients. What are the causes? What are the remedies? ( Bell, DS, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (53.85) | 18.7374 |
| 1990's | 6 (23.08) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Labib, JMW | 1 |
| Aboul-Fotouh, S | 1 |
| Habib, MZ | 1 |
| Mekawy, MAEA | 1 |
| Farrag, KA | 1 |
| Abdel-Tawab, AM | 1 |
| Zargari, O | 1 |
| Gohel, MS | 1 |
| Davies, AH | 1 |
| Wiernsperger, N | 1 |
| Rapin, JR | 1 |
| Koenig, M | 1 |
| Cathébras, P | 1 |
| Guy, C | 1 |
| Rousset, H | 1 |
| Ambrus, JL | 2 |
| Ambrus, CM | 1 |
| Bannerman, R | 1 |
| Sills, RH | 1 |
| Meky, NN | 2 |
| Marcel, GA | 1 |
| Müller, R | 1 |
| Shtok, VN | 1 |
| Fedorova, NV | 1 |
| Gadanova, IV | 1 |
| Keller, F | 1 |
| Leonhardt, H | 1 |
| Reddington, TM | 1 |
| Conway, J | 1 |
| Nagy, Z | 1 |
| Sipka, R | 1 |
| Ocsovszki, I | 1 |
| Balogh, A | 1 |
| Mándi, Y | 1 |
| Kristová, V | 1 |
| Kriska, M | 1 |
| Babál, P | 1 |
| Djibril, MN | 1 |
| Slámová, J | 1 |
| Kurtansky, A | 1 |
| Feine-Haake, G | 1 |
| Dembowski, U | 1 |
| Marx-Heep, I | 1 |
| Adams, HJ | 1 |
| Lagrue, G | 1 |
| Gumpelson, A | 1 |
| Kamalodine, T | 1 |
| Berge, D | 1 |
| Berkenboom, G | 1 |
| Unger, P | 1 |
| Goldman, M | 1 |
| Fang, ZY | 1 |
| Fontaine, J | 1 |
| Bianco, JA | 1 |
| Appelbaum, FR | 1 |
| Nemunaitis, J | 1 |
| Almgren, J | 1 |
| Andrews, F | 1 |
| Kettner, P | 1 |
| Shields, A | 1 |
| Singer, JW | 1 |
| Bell, DS | 1 |
| Wasan, KM | 1 |
| Vadiei, K | 1 |
| Lopez-Berestein, G | 1 |
| Verani, RR | 1 |
| Luke, DR | 1 |
| Soria, J | 1 |
| Soria, C | 1 |
| Bachet, P | 1 |
| Lancrenon, S | 1 |
| Chassoux, G | 1 |
| Clerc, M | 1 |
| Doh-Egueli, D | 1 |
| Chapuis, F | 1 |
| Durin, A | 1 |
| Bertrand, Y | 1 |
| Souillet, G | 1 |
| Philippe, N | 1 |
| Morley, JE | 1 |
| Pallestrini, E | 1 |
| Garaventa, G | 1 |
| Cagetti, P | 1 |
| Benedetti, G | 1 |
| Valle, MT | 1 |
| Accomando, E | 1 |
| Castiglia, G | 1 |
| Spittell, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Topical Pentoxifylline; Metformin Versus Betamethasone in the Treatment of Alopecia Areata: a Clinical and Dermoscopic Study.[NCT06087796] | Phase 1 | 60 participants (Anticipated) | Interventional | 2023-10-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for pentoxifylline and Vascular Diseases
| Article | Year |
|---|---|
Pentoxifylline: a drug with wide spectrum applications in dermatology.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Behcet Syndrome; C | 2008 |
Pharmacological treatment in patients with C4, C5 and C6 venous disease.
Topics: Calcium Dobesilate; Cardiology; Chronic Disease; Compression Bandages; Drug Therapy; Flavonoids; Hum | 2010 |
Microvascular diseases: is a new era coming?
Topics: Diabetic Angiopathies; Hemorheology; Humans; Metformin; Microcirculation; Microvessels; Myocardial I | 2012 |
[Pentoxifylline: a cheap substitute for anti-TNFalpha agents?].
Topics: Clinical Trials as Topic; Humans; Pentoxifylline; Phosphodiesterase Inhibitors; Tumor Necrosis Facto | 2006 |
Hemorheology and peripheral vascular diseases: a new therapeutic approach.
Topics: Blood Viscosity; Clinical Trials as Topic; Humans; Microcirculation; Pentoxifylline; Platelet Aggreg | 1981 |
"Stiff red cell syndrome". A review of the treatment of sickle cell disease with pentoxifylline.
Topics: Animals; Disease Models, Animal; Erythrocytes; Humans; Macaca; Microcirculation; Pentoxifylline; Pla | 1993 |
[The biology of fibrinogen. The role of pentoxifylline].
Topics: Fibrinogen; Fibrinolysis; Humans; Pentoxifylline; Theobromine; Vascular Diseases | 1989 |
4 trials available for pentoxifylline and Vascular Diseases
| Article | Year |
|---|---|
Hemorheology and peripheral vascular diseases: a new therapeutic approach.
Topics: Blood Viscosity; Clinical Trials as Topic; Humans; Microcirculation; Pentoxifylline; Platelet Aggreg | 1981 |
Suppressive effect of pentoxifylline on natural killer cell activity; experimental and clinical studies.
Topics: Adult; Apoptosis; Dose-Response Relationship, Drug; Female; Fluorescent Antibody Technique; Humans; | 1999 |
[Assessment of the therapeutic effect of Trental 400. Double-blind study in geriatric patients with circulatory disorders].
Topics: Aged; Blood Circulation; Extremities; Female; Humans; Intracranial Arteriosclerosis; Long-Term Care; | 1977 |
Phase I-II trial of pentoxifylline for the prevention of transplant-related toxicities following bone marrow transplantation.
Topics: Acute Disease; Acute Kidney Injury; Adult; Bone Marrow Transplantation; Drug Administration Schedule | 1991 |
16 other studies available for pentoxifylline and Vascular Diseases
| Article | Year |
|---|---|
Pentoxifylline ameliorates chronic stress/high-fat diet-induced vascular wall disease: the role of circulating endothelial progenitor cells.
Topics: AC133 Antigen; Animals; Aorta, Thoracic; Body Weight; Chronic Disease; Diet, High-Fat; Endothelial P | 2019 |
Studies on the management and prevention of vasoocclusive crisis in sickle cell disease.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Anemia, Sickle Cell; Animals; Cell Aggregation; Erythrocyte Def | 1984 |
Pharmacological improvement of altered red cell deformability.
Topics: Adenosine Triphosphate; Edetic Acid; Erythrocytes; Humans; Pentoxifylline; Phosphorylation; Risk; Sp | 1981 |
[Clinical study of the cerebrovascular action of pentoxifylline].
Topics: Acute Disease; Adult; Arteriosclerosis; Brain Ischemia; Cerebrovascular Disorders; Chronic Disease; | 1982 |
[Improvement of blood viscosity in sickle-cell anaemia by pentoxifylline (author's transl)].
Topics: Adolescent; Anemia, Sickle Cell; Blood Viscosity; Female; Hemolysis; Humans; Male; Microcirculation; | 1980 |
Evaluation of endothelium-protective effects of drugs in experimental models of endothelial damage.
Topics: Animals; Endothelium, Vascular; Female; Femoral Artery; Glycosaminoglycans; Male; Neutrophils; Norep | 2000 |
[Angioneuropathies, angiolopathies and other disorders of blood circulation. Treatment in ambulatory patients].
Topics: Adult; Aged; Drug Evaluation; Female; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Obes | 1979 |
[The effects of pentoxifylline on microcirculatory changes in the course of arterial diseases (arterial hypertension, diabetes). The value of conjunctival biomicroscopy].
Topics: Capillaries; Conjunctiva; Drug Evaluation; Erythrocytes; Humans; Microscopy; Pentoxifylline; Theobro | 1977 |
Prevention of cyclosporine A-induced vascular toxicity by pentoxifylline.
Topics: Acetylcholine; Animals; Arginine; Colforsin; Cyclosporine; Endothelium, Vascular; Male; Muscle Contr | 1991 |
Lower limb problems in diabetic patients. What are the causes? What are the remedies?
Topics: Amputation, Surgical; Anti-Bacterial Agents; Clinical Protocols; Debridement; Diabetes Complications | 1991 |
Pentoxifylline in amphotericin B toxicity rat model.
Topics: Amphotericin B; Animals; Kidney; Kidney Diseases; Male; Pentoxifylline; Rats; Renal Circulation; The | 1990 |
Fibrinogen and pentoxifylline.
Topics: Fibrinogen; Humans; Pentoxifylline; Theobromine; Vascular Diseases | 1989 |
[Treatment of vaso-occlusive crisis of sickle-cell disease with pentoxifylline].
Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Drug Therapy, Combination; Female; | 1989 |
Impotence in older men.
Topics: Aged; Aged, 80 and over; Drug-Related Side Effects and Adverse Reactions; Erectile Dysfunction; Huma | 1988 |
[Pentoxifylline in changes of the statoacoustic apparatus during vascular diseases. Its action on erythrocyte flexibility].
Topics: Adult; Erythrocyte Deformability; Female; Hearing Disorders; Humans; Male; Microcirculation; Middle | 1986 |
Pentoxifylline and vascular disease.
Topics: Humans; Intermittent Claudication; Pentoxifylline; Theobromine; Vascular Diseases | 1986 |