pentoxifylline has been researched along with Varicose Ulcer in 34 studies
Varicose Ulcer: Skin breakdown or ulceration in the drainage area of a VARICOSE VEIN, usually in the leg.
| Excerpt | Relevance | Reference |
|---|---|---|
| " If confirmed, it wound offer another effective and safe therapeutic option for treatment of VLUs." | 7.30 | Efficacy and safety of pentoxifylline for chronic venous leg ulcers: study protocol for a multicenter randomized controlled trial in China (ESPECT study). ( Chen, L; Dai, Y; Gao, Y; Han, C; Li, B; Li, J; Li, P; Li, Q; Li, Y; Liu, M; Ran, X; Xu, J; Zhao, Y, 2023) |
| "Fusarium species may cause localised skin infections in immunocompetent individuals." | 5.37 | Fusarium oxysporum infection of stasis ulcer: eradication with measures aimed to improve stasis. ( Artunkal, S; Ener, B; Mansur, AT, 2011) |
| "Ten patients with venous leg ulcers and 10 patients with mixed venous/arterial ulcers were investigated with LDF, tcpO2, and LDA before and after injection of prostaglandin E1 and pentoxifylline." | 3.72 | Capillary blood cell velocity in periulcerous regions of the lower leg measured by laser Doppler anemometry. ( Altmeyer, P; Bechara, FG; Hoffmann, K; Huntermann, C; Stücker, M, 2004) |
| "In an open field study, 70 patients with leg ulcers, some existing already for a long time, were treated with Pentoxifylline in addition to the hitherto applied local therapy." | 3.66 | [Trental forte in leg ulcer therapy. Result of a field study]. ( Schmidt-Modrow, G; Weitgasser, H, 1982) |
| " If confirmed, it wound offer another effective and safe therapeutic option for treatment of VLUs." | 3.30 | Efficacy and safety of pentoxifylline for chronic venous leg ulcers: study protocol for a multicenter randomized controlled trial in China (ESPECT study). ( Chen, L; Dai, Y; Gao, Y; Han, C; Li, B; Li, J; Li, P; Li, Q; Li, Y; Liu, M; Ran, X; Xu, J; Zhao, Y, 2023) |
| "Pentoxifylline was found to be more effective than placebo in terms of complete ulcer healing or in causing a significant improvement (greater than 60% reduction in ulcer size) (RR 1." | 2.53 | Pharmacological adjuncts for chronic venous ulcer healing: a systematic review. ( Davies, AH; Lane, T; Munster, AB; Thapar, A; Varatharajan, L, 2016) |
| "Venous ulcers affect approximately 1% of the world's population, increasing healthcare expenditures and decreasing quality of life." | 2.43 | Venous ulcers: pathophysiology and treatment options. ( Eaglstein, WH; Falabella, A; Kirsner, RS; Trent, JT, 2005) |
| "Fusarium species may cause localised skin infections in immunocompetent individuals." | 1.37 | Fusarium oxysporum infection of stasis ulcer: eradication with measures aimed to improve stasis. ( Artunkal, S; Ener, B; Mansur, AT, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (11.76) | 18.7374 |
| 1990's | 7 (20.59) | 18.2507 |
| 2000's | 16 (47.06) | 29.6817 |
| 2010's | 6 (17.65) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L | 1 |
| Gao, Y | 1 |
| Liu, M | 1 |
| Li, Q | 1 |
| Han, C | 1 |
| Zhao, Y | 1 |
| Li, B | 1 |
| Xu, J | 1 |
| Dai, Y | 1 |
| Li, P | 1 |
| Li, J | 1 |
| Li, Y | 1 |
| Ran, X | 1 |
| Nelson, EA | 6 |
| Adderley, U | 1 |
| Stana, J | 1 |
| Stergar, J | 1 |
| Gradišnik, L | 1 |
| Flis, V | 1 |
| Kargl, R | 1 |
| Fröhlich, E | 1 |
| Stana Kleinschek, K | 1 |
| Mohan, T | 1 |
| Maver, U | 1 |
| Lev-Tov, H | 1 |
| Dahle, S | 1 |
| Moss, J | 1 |
| Isseroff, RR | 1 |
| Varatharajan, L | 1 |
| Thapar, A | 1 |
| Lane, T | 1 |
| Munster, AB | 1 |
| Davies, AH | 1 |
| Raju, S | 1 |
| Neglén, P | 1 |
| Jull, A | 2 |
| Walker, N | 1 |
| Parag, V | 1 |
| Molan, P | 1 |
| Rodgers, A | 1 |
| Mansur, AT | 1 |
| Artunkal, S | 1 |
| Ener, B | 1 |
| Word, R | 1 |
| Nikolovska, S | 1 |
| Pavlova, L | 1 |
| Petrova, N | 1 |
| Gocev, G | 1 |
| Ivanovski, M | 1 |
| Cullum, N | 4 |
| Jones, J | 4 |
| Jankūnas, V | 1 |
| Rimdeika, R | 1 |
| Pilipaityte, L | 1 |
| Stücker, M | 1 |
| Huntermann, C | 1 |
| Bechara, FG | 1 |
| Hoffmann, K | 1 |
| Altmeyer, P | 1 |
| Trent, JT | 1 |
| Falabella, A | 1 |
| Eaglstein, WH | 1 |
| Kirsner, RS | 1 |
| Koshkin, VM | 1 |
| Iglesias, CP | 1 |
| Claxton, K | 1 |
| Rajendran, S | 1 |
| Rigby, AJ | 1 |
| Anand, SC | 1 |
| Weitgasser, H | 1 |
| Schmidt-Modrow, G | 1 |
| Colgan, MP | 2 |
| Moore, DJ | 1 |
| Shanik, DG | 2 |
| Mirshahi, S | 1 |
| Soria, J | 1 |
| Mirshahi, M | 1 |
| Soria, C | 1 |
| Lenoble, M | 1 |
| Vasmant, D | 1 |
| Cambazard, F | 1 |
| Claudy, A | 1 |
| Acharya, S | 1 |
| Nair, BC | 1 |
| Franks, PJ | 1 |
| Bosanquet, N | 1 |
| Brown, D | 1 |
| Straub, J | 1 |
| Harper, DR | 1 |
| Ruckley, CV | 1 |
| Renton, EJ | 1 |
| Margolis, DJ | 1 |
| Dormandy, JA | 1 |
| Jones, PW | 1 |
| Schraibman, IG | 1 |
| Young, RA | 1 |
| Gajraj, H | 1 |
| Jopp-McKay, A | 1 |
| Stacey, MC | 1 |
| Angelides, NS | 1 |
| Weil von der Ahe, CA | 1 |
| Galbiati, G | 1 |
| Carnovali, M | 1 |
| Dvorkin, SB | 1 |
| Chernookiĭ, GP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds: A Randomized Controlled Trial[NCT03452072] | Phase 2/Phase 3 | 88 participants (Actual) | Interventional | 2018-08-20 | Completed | ||
| Prospective, Single-arm, Multi-center, Pilot Study of IVUS Imaging Used as an Adjunct to Multiplanar Venography During Iliac-common Femoral Vein Assessment for Possible Endovascular Intervention[NCT02142062] | 100 participants (Actual) | Observational | 2014-07-31 | Completed | |||
| Non-invasive Measurement of Microvascular Blood Flow During Mild External Compression of the Leg[NCT01804478] | 20 participants (Actual) | Interventional | 2005-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for pentoxifylline and Varicose Ulcer
| Article | Year |
|---|---|
Pharmacological adjuncts for chronic venous ulcer healing: a systematic review.
Topics: Female; Humans; Male; MEDLINE; Pentoxifylline; Randomized Controlled Trials as Topic; Varicose Ulcer | 2016 |
Clinical practice. Chronic venous insufficiency and varicose veins.
Topics: Combined Modality Therapy; Female; Humans; Laser Therapy; Middle Aged; Pentoxifylline; Platelet Aggr | 2009 |
Medical and surgical therapy for advanced chronic venous insufficiency.
Topics: Bandages; Chronic Disease; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Leg | 2010 |
Venous leg ulcers.
Topics: Bandages; Biological Dressings; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Pentoxifyl | 2002 |
Venous leg ulcers.
Topics: Bandages; Biological Dressings; Humans; Pentoxifylline; Recurrence; Varicose Ulcer | 2002 |
Venous leg ulcers.
Topics: Bandages; Biological Dressings; Humans; Laser Therapy; Pentoxifylline; Secondary Prevention; Varicos | 2003 |
Venous leg ulcers.
Topics: Bandages; Flavonoids; Glycosaminoglycans; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; | 2004 |
Venous ulcers: pathophysiology and treatment options.
Topics: Anti-Inflammatory Agents; Aspirin; Bandages; Chronic Disease; Debridement; Diosmin; Growth Substance | 2005 |
[The use of pentoxyphylline in the treatment of patients with chronic obliterative diseases of lower limb arteries].
Topics: Administration, Oral; Arterial Occlusive Diseases; Blood Cells; Chronic Disease; Controlled Clinical | 2005 |
New approaches in the medical management of venous ulceration.
Topics: Alprostadil; Diosmin; Humans; Hydroxyethylrutoside; Pentoxifylline; Stanozolol; Varicose Ulcer | 1993 |
Pharmacological treatments for venous leg ulcers.
Topics: Anabolic Agents; Aspirin; Cinnarizine; Fibrinolytic Agents; Histamine H1 Antagonists; Humans; Pentox | 1999 |
7 trials available for pentoxifylline and Varicose Ulcer
| Article | Year |
|---|---|
Efficacy and safety of pentoxifylline for chronic venous leg ulcers: study protocol for a multicenter randomized controlled trial in China (ESPECT study).
Topics: Humans; Leg Ulcer; Multicenter Studies as Topic; Pentoxifylline; Quality of Life; Randomized Control | 2023 |
Venous ulcer management in New Zealand: usual care versus guideline recommendations.
Topics: Aged; Aged, 80 and over; Cohort Studies; Female; Guideline Adherence; Humans; Male; Middle Aged; New | 2009 |
Pentoxifylline--efficient in the treatment of venous ulcers in the absence of compression?
Topics: Adult; Aged; Aged, 80 and over; Bandages; Female; Humans; Male; Middle Aged; Pentoxifylline; Prospec | 2002 |
Expression of elastase and fibrin in venous leg ulcer biopsies: a pilot study of pentoxifylline versus placebo.
Topics: Antibodies, Monoclonal; Fibrin; Humans; Pancreatic Elastase; Paraffin Embedding; Pentoxifylline; Pil | 1995 |
Perceived health in a randomised trial of treatment for chronic venous ulceration.
Topics: Adult; Aged; Aged, 80 and over; Bandages; Chronic Disease; Female; Health Status; Humans; Male; Midd | 1999 |
Pentoxifylline in the treatment of venous leg ulcers.
Topics: Administration, Oral; Bandages; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administ | 2000 |
Oxpentifylline treatment of venous ulcers of the leg.
Topics: Double-Blind Method; Female; Humans; Male; Pentoxifylline; Prognosis; Prospective Studies; Randomize | 1990 |
16 other studies available for pentoxifylline and Varicose Ulcer
| Article | Year |
|---|---|
Venous Leg Ulcers.
Topics: Age Factors; Compression Bandages; Humans; Leg Ulcer; Pentoxifylline; Platelet Aggregation Inhibitor | 2017 |
Multilayered Polysaccharide Nanofilms for Controlled Delivery of Pentoxifylline and Possible Treatment of Chronic Venous Ulceration.
Topics: Alginates; Cell Line; Chitosan; Humans; Nanostructures; Pentoxifylline; Platelet Aggregation Inhibit | 2017 |
Successful treatment of a chronic venous leg ulcer using a topical beta-blocker.
Topics: Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Aged; Biopsy, Needle; Do | 2013 |
Fusarium oxysporum infection of stasis ulcer: eradication with measures aimed to improve stasis.
Topics: Antifungal Agents; Dermatologic Agents; Fusarium; Humans; Male; Middle Aged; Mycoses; Organometallic | 2011 |
Healing venous ulcers without compression.
Topics: Bandages; Bandages, Hydrocolloid; Colloids; Evidence-Based Medicine; Flavonoids; Hematologic Agents; | 2003 |
Treatment of the leg ulcers by skin grafting.
Topics: Adult; Aged; Aged, 80 and over; Bandages; Colloids; Female; Follow-Up Studies; Hematologic Agents; H | 2004 |
Capillary blood cell velocity in periulcerous regions of the lower leg measured by laser Doppler anemometry.
Topics: Aged; Aged, 80 and over; Alprostadil; Blood Flow Velocity; Capillaries; Case-Control Studies; Erythr | 2004 |
Pentoxifylline for leg ulcers.
Topics: Austria; Denmark; Hematologic Agents; Humans; Leg Ulcer; Pentoxifylline; Randomized Controlled Trial | 2005 |
Comprehensive decision-analytic model and Bayesian value-of-information analysis: pentoxifylline in the treatment of chronic venous leg ulcers.
Topics: Administration, Oral; Adolescent; Adult; Aged; Bayes Theorem; Chronic Disease; Cost-Benefit Analysis | 2006 |
Venous leg ulcer treatment and practice--Part 4: Surgery and pharmaceutical therapies.
Topics: Flavonoids; Humans; Pentoxifylline; Sclerotherapy; Varicose Ulcer; Vasodilator Agents | 2007 |
[Trental forte in leg ulcer therapy. Result of a field study].
Topics: Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Leg Ulcer; Male; Middle | 1982 |
Pentoxifylline-induced thrombocytopenia.
Topics: Blood Platelets; Humans; Pentoxifylline; Platelet Count; Thrombocytopenia; Varicose Ulcer; Vasodilat | 1997 |
Oxpentifylline treatment of venous leg ulcers.
Topics: Bandages; Humans; Pentoxifylline; Theobromine; Varicose Ulcer | 1990 |
Effect of oral pentoxifylline therapy on venous lower extremity ulcers due to deep venous incompetence.
Topics: Administration, Oral; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Pentoxifylline | 1989 |
[Usefulness of pentoxifylline in the therapy of venous and mixed dystrophic ulcers of the legs].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Drug Evaluation; Female; Humans; Male; Middle | 1987 |
[Conservative treatment of trophic leg ulcers with trental].
Topics: Adult; Aged; Chronic Disease; Drug Evaluation; Female; Humans; Male; Middle Aged; Pentoxifylline; Th | 1985 |