pentoxifylline has been researched along with Ureteral Obstruction in 2 studies
Ureteral Obstruction: Blockage in any part of the URETER causing obstruction of urine flow from the kidney to the URINARY BLADDER. The obstruction may be congenital, acquired, unilateral, bilateral, complete, partial, acute, or chronic. Depending on the degree and duration of the obstruction, clinical features vary greatly such as HYDRONEPHROSIS and obstructive nephropathy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentoxifylline (PTX) is a potent inhibitor of connective tissue growth factor (CTGF), but its underlying mechanism is poorly understood." | 5.33 | Pentoxifylline attenuates tubulointerstitial fibrosis by blocking Smad3/4-activated transcription and profibrogenic effects of connective tissue growth factor. ( Chen, RH; Chen, YM; Chiang, WC; Lai, CF; Lin, SL; Tsai, TJ; Wu, KD, 2005) |
| "Pentoxifylline (PTX) is a potent inhibitor of connective tissue growth factor (CTGF), but its underlying mechanism is poorly understood." | 1.33 | Pentoxifylline attenuates tubulointerstitial fibrosis by blocking Smad3/4-activated transcription and profibrogenic effects of connective tissue growth factor. ( Chen, RH; Chen, YM; Chiang, WC; Lai, CF; Lin, SL; Tsai, TJ; Wu, KD, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aslan, A | 1 |
| Karagüzel, G | 1 |
| Güngör, F | 1 |
| Izgüt-Uysal, N | 1 |
| Aydin, F | 1 |
| Melikoğlu, M | 1 |
| Lin, SL | 1 |
| Chen, RH | 1 |
| Chen, YM | 1 |
| Chiang, WC | 1 |
| Lai, CF | 1 |
| Wu, KD | 1 |
| Tsai, TJ | 1 |
2 other studies available for pentoxifylline and Ureteral Obstruction
| Article | Year |
|---|---|
The effects of pentoxifylline on renal function and free radical production in unilateral ureteral obstruction.
Topics: Animals; Female; Free Radicals; Kidney; Pentoxifylline; Rats; Ureteral Obstruction | 2003 |
Pentoxifylline attenuates tubulointerstitial fibrosis by blocking Smad3/4-activated transcription and profibrogenic effects of connective tissue growth factor.
Topics: Actins; Angiotensin II; Animals; Cell Line; Collagen Type I; Connective Tissue Growth Factor; Fibros | 2005 |