Page last updated: 2024-11-02

pentoxifylline and Thrombosis

pentoxifylline has been researched along with Thrombosis in 36 studies

Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.

Research Excerpts

ExcerptRelevanceReference
"Shunt thrombosis was assumed when the flow in the shunt discontinued under visual and auscultatory control."6.66Shunt thrombosis prevention in hemodialysis patients--a double-blind, randomized study: pentoxifylline vs placebo. ( Borić, Z; Muśikić, P; Naumović, T; Radmilović, A; Stamenković, M, 1987)
"injection inhibited thrombus formation in small mesenteric vessels for more than 12 hours but less than 24 hours."5.28[Evaluation of the antithrombotic effects of pentoxifylline, acetylsalicylic acid and low molecular weight heparin in the laser model of thrombosis]. ( Bielawiec, M; Breddin, HK; Krupiński, K; Płonowski, A, 1992)
"The authors studied the effect of pentoxifylline (Trental), a hemorrheologic agent that increases erythrocyte flexibility and augments microcirculatory blood flow, on the patency of a known thrombosis model."3.69The use of pentoxifylline in microvascular surgery. ( Ferder, M; Hunzicker, K; Kronen, G; Strauch, B, 1994)
"The hamster cheek pouch model of experimental thrombosis in which thrombi are induced in the microvasculature by iontophoretical administration of adenosine diphosphate (ADP) was used to test the antithrombotic potential of pentoxifylline (Trental)."3.67Reduced thrombus formation in vivo after administration of pentoxifylline (Trental). ( Giessinger, N; Michal, M; Schröer, R, 1989)
"The effect of the combined oral administration of pentoxifylline (pof) and low dose acetylsalicylic acid (ASA) was evaluated with the help of the laser-induced thrombosis in rat mesenteric arterioles."3.67Surprising effects of the sequential administration of pentoxifylline and low dose acetylsalicylic acid on thrombus formation. ( Seiffge, D; Weithmann, KU, 1987)
"Shunt thrombosis was assumed when the flow in the shunt discontinued under visual and auscultatory control."2.66Shunt thrombosis prevention in hemodialysis patients--a double-blind, randomized study: pentoxifylline vs placebo. ( Borić, Z; Muśikić, P; Naumović, T; Radmilović, A; Stamenković, M, 1987)
"Counterproductive lung inflammation and dysregulated thrombosis contribute importantly to the lethality of advanced COVID-19."1.56Harnessing adenosine A2A receptors as a strategy for suppressing the lung inflammation and thrombotic complications of COVID-19: Potential of pentoxifylline and dipyridamole. ( Barroso-Aranda, J; DiNicolantonio, JJ, 2020)
"injection inhibited thrombus formation in small mesenteric vessels for more than 12 hours but less than 24 hours."1.28[Evaluation of the antithrombotic effects of pentoxifylline, acetylsalicylic acid and low molecular weight heparin in the laser model of thrombosis]. ( Bielawiec, M; Breddin, HK; Krupiński, K; Płonowski, A, 1992)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199016 (44.44)18.7374
1990's7 (19.44)18.2507
2000's8 (22.22)29.6817
2010's2 (5.56)24.3611
2020's3 (8.33)2.80

Authors

AuthorsStudies
Bayraktar, S1
Tanyeri-Bayraktar, B1
Assimakopoulos, SF1
Seintis, F1
Marangos, M1
DiNicolantonio, JJ1
Barroso-Aranda, J1
Plotnikov, MB1
Smolyakova, VI1
Ivanov, IS1
Kuchin, AV1
Chukicheva, IJ1
Krasnov, EA1
Diskin, CJ2
Jenkins, J1
Babu, K1
Hsu-Hung, E1
Robinson-Bostom, L1
Kroumpouzos, G1
Melnik, B1
Hariry, H1
Vakilzadeh, F1
Gropp, C1
Sitzer, G1
Murthy, P1
Riesberg, MV1
Hart, S1
Bustillo, A1
Duque, CS1
Said, S1
Civantos, FJ1
Hödl, S1
Usküdar, O1
Erdem, A1
Demiroğlu, H1
Dikmenoğlu, N1
Il'in, VN2
Stepanov, NV1
Ikhaev, ZA1
Sharonin, GV1
Bogdanets, LI1
Dintenfass, L1
Lucas, MA1
Ambrus, JL1
Ambrus, CM1
Stadler, S1
Toumbis, C1
Markus, G1
Kronen, G1
Ferder, M1
Hunzicker, K1
Strauch, B1
de Prost, D1
Colen, LB1
Stevenson, A1
Sidorov, V1
Potparic, Z1
Pacelli, E1
Searles, J1
Lee, S1
Li, L1
Stokes, TJ1
Thomas, SG1
Ravis, W1
Lock, S1
Thomas, J1
Panus, LW1
Dansby, L1
Carter, T1
Poliantsev, AA1
Spasov, AA1
Mozgovoĭ, PV1
Karpenko, AV1
Shcherbakov, VN1
Kuznetsov, VI1
Khomutnikova, AI1
Kirichenko, OM1
Souza, CS1
Roselino, AM1
Figueiredo, F1
Foss, NT1
Jaimes, EA1
Castillo, DD1
Rutherford, MS1
Raij, L1
Shestakov, VA2
Rodionov, SV1
Danilova, LM1
Müller, R2
Zatevakhin, II1
Koshkin, VM2
Il'in, SG1
Adil'khanov, SG2
Antonova, NIu1
Lehrach, F1
Theis, H1
Krupiński, K1
Breddin, HK2
Bielawiec, M1
Płonowski, A1
Vyalov, SL1
Rekhter, MD1
Sidorov, VB1
Pshenisnov, KP1
Mironov, AA1
Michal, M1
Giessinger, N1
Schröer, R1
Neugodov, IuV1
Sokolov, GF1
Popov, VV1
El'skaia, IE1
Seiffge, D2
Weithmann, KU2
Radmilović, A1
Borić, Z1
Naumović, T1
Stamenković, M1
Muśikić, P1
Weichert, W1
Schröer, RH1
Kovaleva, LG1
Sedova, GT1
Krasiukova, LI1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pentoxifylline Dose Optimization in Preterm Neonatal Late Onset Sepsis[NCT04152980]Phase 340 participants (Anticipated)Interventional2020-01-12Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for pentoxifylline and Thrombosis

ArticleYear
Novel insights into the pathobiology of the vascular access - do they translate into improved care?
    Blood purification, 2010, Volume: 29, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Arteriovenous Shunt, Surgical; Calcium Cha

2010
Action of drugs on the aggregation and deformability of red cells: effect of ABO blood groups.
    Annals of the New York Academy of Sciences, 1983, Volume: 416

    Topics: ABO Blood-Group System; Alprenolol; Blood Coagulation; Blood Viscosity; Cell Adhesion; Erythrocyte A

1983
Pentoxifylline: a potential treatment for thrombosis associated with abnormal tissue factor expression by monocytes and endothelial cells.
    Journal of cardiovascular pharmacology, 1995, Volume: 25 Suppl 2

    Topics: Endothelium, Vascular; Humans; Monocytes; Pentoxifylline; Thromboplastin; Thrombosis; Vasodilator Ag

1995
Pentoxifylline -- a biomedical profile.
    Journal of medicine, 1979, Volume: 10, Issue:5

    Topics: Arterial Occlusive Diseases; Blood Viscosity; Brain Ischemia; Cerebrovascular Circulation; Erythrocy

1979

Trials

3 trials available for pentoxifylline and Thrombosis

ArticleYear
Prevention of post-operative thrombosis in peripheral arteriopathies. Pentoxifylline vs. conventional antiaggregants: a six-month randomized follow-up study.
    Angiology, 1984, Volume: 35, Issue:7

    Topics: Aged; Aspirin; Dipyridamole; Drug Tolerance; Female; Follow-Up Studies; Humans; Male; Middle Aged; P

1984
[Antithrombotic prophylaxis after surgical interventions on the major veins].
    Kardiologiia, 1978, Volume: 18, Issue:8

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Dextrans; Drug Combinations; Drug Evaluation; Fem

1978
Shunt thrombosis prevention in hemodialysis patients--a double-blind, randomized study: pentoxifylline vs placebo.
    Angiology, 1987, Volume: 38, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Arteriovenous Shunt, Surgical; Clinical Trials as Topic; Double-Blin

1987

Other Studies

29 other studies available for pentoxifylline and Thrombosis

ArticleYear
Pentoxifylline in the treatment of neonatal vasospasm and thromboembolism: An observational case series study.
    Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:4

    Topics: Humans; Infant, Newborn; Pentoxifylline; Retrospective Studies; Spasm; Thromboembolism; Thrombosis

2022
Pentoxifylline and complicated COVID-19: A pathophysiologically based treatment proposal.
    Medical hypotheses, 2020, Volume: 143

    Topics: Antibodies, Monoclonal, Humanized; Betacoronavirus; Blood Coagulation Disorders; Coronavirus Infecti

2020
Harnessing adenosine A2A receptors as a strategy for suppressing the lung inflammation and thrombotic complications of COVID-19: Potential of pentoxifylline and dipyridamole.
    Medical hypotheses, 2020, Volume: 143

    Topics: Adenosine A2 Receptor Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Betacoronavirus; C

2020
Antithrombogenic and antiplatelet activity of optho-isobornyl phenol derivative.
    Bulletin of experimental biology and medicine, 2008, Volume: 145, Issue:3

    Topics: Animals; Brain Ischemia; Camphanes; Cresols; Fibrinolytic Agents; Male; Pentoxifylline; Platelet Agg

2008
ANCA-positive necrotizing vasculitis and thrombotic vasculopathy induced by levamisole-adulterated cocaine: a distinctive clinicopathologic presentation.
    Journal of the American Academy of Dermatology, 2011, Volume: 65, Issue:1

    Topics: Adrenal Cortex Hormones; Antibodies, Antineutrophil Cytoplasmic; Aspirin; Biopsy, Needle; Cocaine-Re

2011
[Malignant atrophic papulosis (Köhlmeier-Degos disease). Failure to respond to interferon alpha-2a, pentoxifylline and aspirin].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2002, Volume: 53, Issue:9

    Topics: Aspirin; Atrophy; Connective Tissue; Diagnosis, Differential; Disease Progression; Drug Therapy, Com

2002
Efficacy of perioperative thromboprophylactic agents in the maintenance of anastamotic patency and survival of rat microvascular free groin flaps.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2003, Volume: 129, Issue:3

    Topics: Abdomen; Anastomosis, Surgical; Animals; Anticoagulants; Femoral Artery; Groin; Heparin, Low-Molecul

2003
[Treatment of freezing injury].
    Wiener medizinische Wochenschrift (1946), 2005, Volume: 155, Issue:7-8

    Topics: Blood Viscosity; Cell Death; Cold Temperature; Combined Modality Therapy; Endothelium, Vascular; Foo

2005
Decreased erythrocyte deformability in Behçet's disease.
    Clinical hemorheology and microcirculation, 2005, Volume: 33, Issue:2

    Topics: Adult; Behcet Syndrome; Case-Control Studies; Erythrocyte Deformability; Female; Humans; Male; Middl

2005
[Postoperative antithrombotic therapy in acute occlusion of the major arteries of the extremities].
    Vestnik khirurgii imeni I. I. Grekova, 1980, Volume: 125, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Arm; Arterial Occlusive Diseases; Aspirin; Dextrans; Female;

1980
Potentiation of thrombolytic therapy by enzyme combinations and with aspirin or pentoxifylline.
    Journal of medicine, 1994, Volume: 25, Issue:3-4

    Topics: Animals; Aspirin; Drug Synergism; Drug Therapy, Combination; Macaca; Pentoxifylline; Platelet Aggreg

1994
The use of pentoxifylline in microvascular surgery.
    Journal of reconstructive microsurgery, 1994, Volume: 10, Issue:1

    Topics: Animals; Double-Blind Method; Femoral Artery; Injections, Intraperitoneal; Microcirculation; Microsu

1994
Microvascular anastomotic thrombosis in experimental diabetes mellitus.
    Plastic and reconstructive surgery, 1997, Volume: 99, Issue:1

    Topics: Anastomosis, Surgical; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Angiopathie

1997
An analysis of the effect of routine medications on hemodialysis vascular access survival.
    Nephron, 1998, Volume: 78, Issue:3

    Topics: Arteriovenous Shunt, Surgical; Humans; Pentoxifylline; Phosphodiesterase Inhibitors; Proportional Ha

1998
[Prevention of early thrombotic complications after reconstructive operations in occlusions of the aorto-iliac segment].
    Khirurgiia, 2000, Issue:9

    Topics: Adult; Aged; Anticoagulants; Aorta, Abdominal; Aortic Diseases; Arterial Occlusive Diseases; Aspirin

2000
Lucio's phenomenon: clinical and therapeutic aspects.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 2000, Volume: 68, Issue:4

    Topics: Aged; Anti-Inflammatory Agents; Brazil; Disease Progression; Endothelium, Vascular; Fatal Outcome; F

2000
Countervailing influence of tumor necrosis factor-alpha and nitric oxide in endotoxemia.
    Journal of the American Society of Nephrology : JASN, 2001, Volume: 12, Issue:6

    Topics: Analysis of Variance; Animals; Endotoxemia; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Es

2001
[Effect of papaverine and trental on hemostasis and rheologic properties of blood in acute arterial obstruction].
    Problemy gematologii i perelivaniia krovi, 1979, Volume: 24, Issue:12

    Topics: Acute Disease; Blood Viscosity; Hemostasis; Humans; Papaverine; Pentoxifylline; Theobromine; Thrombo

1979
[Peripheral macro-and microcirculatory changes in acute arterial obstruction with papaverine and trental administration].
    Vestnik khirurgii imeni I. I. Grekova, 1979, Volume: 123, Issue:12

    Topics: Acute Disease; Arterial Occlusive Diseases; Blood Circulation; Drug Evaluation; Embolism; Hemodynami

1979
[5 years of clinico-experimental and therapeutic experiences with pentoxifylline].
    Medizinische Monatsschrift, 1977, Volume: 31, Issue:4

    Topics: Arterial Occlusive Diseases; Cerebrovascular Disorders; Chemical Phenomena; Chemistry; Eye Diseases;

1977
[Evaluation of the antithrombotic effects of pentoxifylline, acetylsalicylic acid and low molecular weight heparin in the laser model of thrombosis].
    Kardiologia polska, 1992, Volume: 36, Issue:3

    Topics: Animals; Aspirin; Disease Models, Animal; Heparin, Low-Molecular-Weight; In Vitro Techniques; Lasers

1992
Formation of endovasal structures and intramural channels in rat vena cava after application of microsurgical suture: prophylactic effect of heparin and trental administration.
    Microsurgery, 1992, Volume: 13, Issue:3

    Topics: Anastomosis, Surgical; Animals; Blood Platelets; Connective Tissue; Endothelium, Vascular; Fibrin; H

1992
Reduced thrombus formation in vivo after administration of pentoxifylline (Trental).
    Thrombosis research, 1989, Nov-01, Volume: 56, Issue:3

    Topics: Adenosine Diphosphate; Animals; Cheek; Cricetinae; Fibrinolytic Agents; Injections, Intraperitoneal;

1989
[The onset of circulatory venous gangrene of the arm and its successful treatment by thrombolysis].
    Vestnik khirurgii imeni I. I. Grekova, 1989, Volume: 143, Issue:11

    Topics: Adult; Arm; Drug Therapy, Combination; Female; Fibrinolytic Agents; Gangrene; Heparin; Humans; Infus

1989
Update on the pharmacology of pentoxifylline and its combination with low-dose acetylsalicylic acid (HWA 5112).
    Seminars in thrombosis and hemostasis, 1989, Volume: 15, Issue:2

    Topics: Animals; Aspirin; Blood Flow Velocity; Blood Viscosity; Dose-Response Relationship, Drug; Drug Thera

1989
Surprising effects of the sequential administration of pentoxifylline and low dose acetylsalicylic acid on thrombus formation.
    Thrombosis research, 1987, Apr-15, Volume: 46, Issue:2

    Topics: Administration, Oral; Animals; Aspirin; Drug Administration Schedule; Drug Synergism; Lasers; Male;

1987
Antithrombotic effects of acetylsalicylic acid (ASA) and pentoxifylline in laser-induced thrombosis in rat mesenteric vessels.
    VASA. Zeitschrift fur Gefasskrankheiten, 1985, Volume: 14, Issue:3

    Topics: Animals; Aspirin; Dose-Response Relationship, Drug; In Vitro Techniques; Laser Therapy; Male; Mesent

1985
Antithrombotic potential of pentoxifylline. A hemorheologically active drug.
    Angiology, 1985, Volume: 36, Issue:6

    Topics: Animals; Aspirin; Blood Coagulation; Cricetinae; Epoprostenol; Fibrinolysis; Haplorhini; Hemostasis;

1985
[Preventive correction of hemostasis in patients with polycythemia vera].
    Gematologiia i transfuziologiia, 1986, Volume: 31, Issue:2

    Topics: Aspirin; Humans; Niacin; Pentoxifylline; Polycythemia Vera; Theobromine; Thrombosis

1986