Page last updated: 2024-11-02

pentoxifylline and Skin Diseases

pentoxifylline has been researched along with Skin Diseases in 17 studies

Skin Diseases: Diseases involving the DERMIS or EPIDERMIS.

Research Excerpts

ExcerptRelevanceReference
"Eight patients with livedo vasculitis of four to 30 years' duration that was unresponsive to a variety of medications were treated with pentoxifylline."7.67Livedo vasculitis. Therapy with pentoxifylline. ( Sams, WM, 1988)
"To characterize the effects of pentoxifylline on the gross and microscopic variables associated with immediate and late-phase inflammation following injection of IgE-specific antibodies in the skin of clinically normal dogs."5.19Effects of pentoxifylline on immediate and late-phase cutaneous reactions in response to anti-immunoglobulin E antibodies in clinically normal dogs. ( Hammerberg, B; Kasparek, KA; Kearney, MT; Pucheu-Haston, CM; Stout, RW, 2014)
"The widely accepted standard therapy for cutaneous sarcoidosis includes corticosteroids, antimalarials, and methotrexate."4.84Cutaneous sarcoidosis therapy updated. ( Badgwell, C; Rosen, T, 2007)
"Eight patients with livedo vasculitis of four to 30 years' duration that was unresponsive to a variety of medications were treated with pentoxifylline."3.67Livedo vasculitis. Therapy with pentoxifylline. ( Sams, WM, 1988)
"The causes of pruritus are numerous including xerosis, drug and photoeruptions, follicular and papular eruptions as well as infestations and infections by a wide range of organisms."2.68Pruritus in HIV-1 disease: therapy with drugs which may modulate the pattern of immune dysregulation. ( Lee, RB; Skelton, HG; Smith, KJ; Wagner, KF; Yeager, J, 1997)
"Pentoxifylline (PTX) is a methylxanthine derivative with a variety of anti-inflammatory effects."2.44Pentoxifylline: a drug with wide spectrum applications in dermatology. ( Zargari, O, 2008)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's5 (29.41)18.2507
2000's4 (23.53)29.6817
2010's4 (23.53)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Lubsen, J1
Kelly, RI1
Wee, E1
Tancharoen, C1
Tam, MM1
Balta, S1
Williams, RA1
Pucheu-Haston, CM1
Kasparek, KA1
Stout, RW1
Kearney, MT1
Hammerberg, B1
Fichter, AM1
Ritschl, LM1
Robitzky, LK1
Wagenpfeil, S1
Mitchell, DA1
Wolff, KD1
Mücke, T1
Zargari, O1
Kiken, DA1
Goldman, MP1
Çakmak, SK1
Çakmak, A1
Gönül, M1
Kiliç, A1
Gül, Ü1
Badgwell, C1
Rosen, T1
Samlaska, CP1
Winfield, EA1
Ely, H2
Smith, KJ1
Skelton, HG1
Yeager, J1
Lee, RB1
Wagner, KF1
Weinberg, JM1
Ioffreda, M1
White, SM1
Rudolph, RI1
Kramer, EM1
Montgomery, B1
Bianco, JA1
Jacobsen, A1
Singer, JW1
Berman, B1
Duncan, MR1
Sams, WM1
Sauer, GC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Topical Pentoxifylline; Metformin Versus Betamethasone in the Treatment of Alopecia Areata: a Clinical and Dermoscopic Study.[NCT06087796]Phase 160 participants (Anticipated)Interventional2023-10-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for pentoxifylline and Skin Diseases

ArticleYear
Pentoxifylline: a drug with wide spectrum applications in dermatology.
    Dermatology online journal, 2008, Nov-15, Volume: 14, Issue:11

    Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Behcet Syndrome; C

2008
Pentoxifylline use in dermatology.
    Inflammation & allergy drug targets, 2012, Volume: 11, Issue:6

    Topics: Animals; Cytokines; Down-Regulation; Drug Costs; Humans; Microcirculation; Pentoxifylline; Phosphodi

2012
Cutaneous sarcoidosis therapy updated.
    Journal of the American Academy of Dermatology, 2007, Volume: 56, Issue:1

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Allopurinol; Animals; Anti-Inflammatory Agents

2007
Pentoxifylline.
    Journal of the American Academy of Dermatology, 1994, Volume: 30, Issue:4

    Topics: Animals; Blood Coagulation; Connective Tissue; Dose-Response Relationship, Drug; Drug Interactions;

1994
Pentoxifylline therapy in dermatology. A review of localized hyperviscosity and its effects on the skin.
    Dermatologic clinics, 1988, Volume: 6, Issue:4

    Topics: Blood Cells; Blood Viscosity; Drug Interactions; Humans; Pentoxifylline; Skin; Skin Diseases; Theobr

1988

Trials

2 trials available for pentoxifylline and Skin Diseases

ArticleYear
Effects of pentoxifylline on immediate and late-phase cutaneous reactions in response to anti-immunoglobulin E antibodies in clinically normal dogs.
    American journal of veterinary research, 2014, Volume: 75, Issue:2

    Topics: Administration, Cutaneous; Animals; Antibodies, Anti-Idiotypic; Dog Diseases; Dogs; Free Radical Sca

2014
Pruritus in HIV-1 disease: therapy with drugs which may modulate the pattern of immune dysregulation.
    Dermatology (Basel, Switzerland), 1997, Volume: 195, Issue:4

    Topics: Administration, Cutaneous; Administration, Topical; Anti-Inflammatory Agents; Antipruritics; Cycloox

1997

Other Studies

10 other studies available for pentoxifylline and Skin Diseases

ArticleYear
Worsening skin lesions but no diagnosis.
    The Journal of family practice, 2020, Volume: 69, Issue:10

    Topics: Aspirin; Biopsy; Female; Humans; Malignant Atrophic Papulosis; Middle Aged; Pentoxifylline; Platelet

2020
Three cases of lymphocytic thrombophilic arteritis presenting with an annular eruption.
    The Australasian journal of dermatology, 2018, Volume: 59, Issue:2

    Topics: Adult; Arteritis; Aspirin; Female; Fibrinolytic Agents; Humans; Lymphocytes; Middle Aged; Pentoxifyl

2018
Impact of different antithrombotics on the microcirculation and viability of perforator-based ischaemic skin flaps in a small animal model.
    Scientific reports, 2016, 10-21, Volume: 6

    Topics: Animals; Aspirin; Clopidogrel; Disease Models, Animal; Fibrinolytic Agents; Graft Survival; Heparin;

2016
Inadvertent injection of sodium tetradecyl sulfate during placement of mental nerve block: discussion of management and outcome.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2009, Volume: 35, Issue:12

    Topics: Adult; Biocompatible Materials; Female; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Hyperbari

2009
Is pentoxifylline the drug of the decade?
    Journal of the American Academy of Dermatology, 1994, Volume: 30, Issue:4

    Topics: Clinical Trials as Topic; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Human

1994
Purplish papules on the legs. Diagnosis: type I cryoglobulinemia in association with WM.
    Archives of dermatology, 2000, Volume: 136, Issue:10

    Topics: Aged; Betamethasone; Chlorambucil; Cryoglobulinemia; Diagnosis, Differential; Drug Therapy, Combinat

2000
Localization of transfused neutrophils to site of infection during treatment with recombinant human granulocyte-macrophage colony-stimulating factor and pentoxifylline.
    Blood, 1991, Jul-15, Volume: 78, Issue:2

    Topics: Abscess; Adult; Blood Transfusion; Bone Marrow Transplantation; Candidiasis; Granulocyte-Macrophage

1991
Pentoxifylline inhibits the proliferation of human fibroblasts derived from keloid, scleroderma and morphoea skin and their production of collagen, glycosaminoglycans and fibronectin.
    The British journal of dermatology, 1990, Volume: 123, Issue:3

    Topics: Cell Division; Collagen; Depression, Chemical; Fibroblasts; Fibronectins; Glycosaminoglycans; Humans

1990
Livedo vasculitis. Therapy with pentoxifylline.
    Archives of dermatology, 1988, Volume: 124, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Dipyridamole; Drug Therapy, Combination; Female; Humans; Ma

1988
Pentoxifylline (Trental) therapy for the vasculitis of atrophie blanche.
    Archives of dermatology, 1986, Volume: 122, Issue:4

    Topics: Adult; Aged; Atrophy; Female; Humans; Leg; Male; Middle Aged; Pentoxifylline; Skin; Skin Diseases; T

1986