Page last updated: 2024-11-02

pentoxifylline and Sarcoidosis

pentoxifylline has been researched along with Sarcoidosis in 6 studies

Sarcoidosis: An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands.

Research Excerpts

ExcerptRelevanceReference
"We present the case of a patient with sarcoidosis corticodependent despite the use of azathioprine."7.88[The pentoxifylline, a corticosteroid sparing in the treatment of sarcoidosis: A case report]. ( Diallo, BD; Diot, B; Diot, P; Flament, T; Marchand-Adam, S; Plantier, L; Sow, OY, 2018)
"The widely accepted standard therapy for cutaneous sarcoidosis includes corticosteroids, antimalarials, and methotrexate."4.84Cutaneous sarcoidosis therapy updated. ( Badgwell, C; Rosen, T, 2007)
"We present the case of a patient with sarcoidosis corticodependent despite the use of azathioprine."3.88[The pentoxifylline, a corticosteroid sparing in the treatment of sarcoidosis: A case report]. ( Diallo, BD; Diot, B; Diot, P; Flament, T; Marchand-Adam, S; Plantier, L; Sow, OY, 2018)
"Pentoxifylline (PTX) is a methylxanthine derivative with a variety of anti-inflammatory effects."2.44Pentoxifylline: a drug with wide spectrum applications in dermatology. ( Zargari, O, 2008)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diallo, BD1
Diot, B1
Flament, T1
Plantier, L1
Diot, P1
Sow, OY1
Marchand-Adam, S1
Zargari, O1
Antoniu, SA1
Moller, DR1
Badgwell, C1
Rosen, T1
Körber, M1
Kamp, S1
Kothe, H1
Braun, J1
Dalhoff, K1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Topical Pentoxifylline; Metformin Versus Betamethasone in the Treatment of Alopecia Areata: a Clinical and Dermoscopic Study.[NCT06087796]Phase 160 participants (Anticipated)Interventional2023-10-31Not yet recruiting
Clinical Biomarkers of Disease Activity and Treatment Responses in Patients With CNS Sarcoidosis Treated With H.P. Acthar Gel[NCT02298491]Phase 44 participants (Actual)Interventional2016-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Total Number of Lesions

Total number of lesions assessed at 1 year (NCT02298491)
Timeframe: 1 year

Interventionlesions (Number)
H.P. Acthar Gel5

Reviews

4 reviews available for pentoxifylline and Sarcoidosis

ArticleYear
Pentoxifylline: a drug with wide spectrum applications in dermatology.
    Dermatology online journal, 2008, Nov-15, Volume: 14, Issue:11

    Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Behcet Syndrome; C

2008
Targeting the TNF-alpha pathway in sarcoidosis.
    Expert opinion on therapeutic targets, 2010, Volume: 14, Issue:1

    Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Eta

2010
Treatment of sarcoidosis -- from a basic science point of view.
    Journal of internal medicine, 2003, Volume: 253, Issue:1

    Topics: Etanercept; Granuloma; Humans; Immunoglobulin G; Immunosuppressive Agents; Interleukins; Pentoxifyll

2003
Cutaneous sarcoidosis therapy updated.
    Journal of the American Academy of Dermatology, 2007, Volume: 56, Issue:1

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Allopurinol; Animals; Anti-Inflammatory Agents

2007

Other Studies

2 other studies available for pentoxifylline and Sarcoidosis

ArticleYear
[The pentoxifylline, a corticosteroid sparing in the treatment of sarcoidosis: A case report].
    Revue de pneumologie clinique, 2018, Volume: 74, Issue:1

    Topics: Azathioprine; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Middle Aged; Pentoxifylline

2018
[Pentoxifylline inhibits secretion of O2- and TNF-alpha by alveolar macrophages in patients with sarcoidosis].
    Immunitat und Infektion, 1995, Volume: 23, Issue:3

    Topics: Adult; Female; Humans; In Vitro Techniques; Macrophages, Alveolar; Male; Pentoxifylline; Respiratory

1995