pentoxifylline has been researched along with Respiratory Distress Syndrome in 42 studies
Respiratory Distress Syndrome: A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether the administration of lisofylline (1-[5R-hydroxyhexyl]-3,7-dimethylxanthine) would decrease mortality in patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS)." | 9.10 | Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome. ( , 2002) |
| " Resuscitation with hypertonic saline and pentoxifylline (HSPTX) has been shown to attenuate hemorrhagic shock-induced injury when compared with RL." | 7.74 | Hypertonic saline and pentoxifylline reduces hemorrhagic shock resuscitation-induced pulmonary inflammation through attenuation of neutrophil degranulation and proinflammatory mediator synthesis. ( Coimbra, R; de Campos, T; Deree, J; Hoyt, DB; Lamon, B; Leedom, A; Martins, JO; Putnam, J; Wolf, P, 2007) |
| " We hypothesized that the anti-inflammatory agent pentoxifylline (PTX) attenuates postresuscitative lung injury through modulation of transcription factors after hemorrhagic shock." | 7.74 | Pentoxifylline attenuates lung injury and modulates transcription factor activity in hemorrhagic shock. ( Coimbra, R; de Campos, T; Deree, J; Loomis, WH; Martins, J; Putnam, JG; Wolf, P, 2007) |
| "To assess the effects of pentoxifylline posttreatment on hemodynamic variables and acute pulmonary injury in the rat intestinal ischemia-reperfusion (I-R) model, using a recently developed method of fluorescent intravital pulmonary videomicroscopy." | 7.69 | Pentoxifylline attenuates pulmonary macromolecular leakage after intestinal ischemia-reperfusion. ( Carter, MB; Garrison, RN; Wead, WB; Wilson, MA, 1995) |
| "We studied the effects of pentoxifylline (PTX) on the polymorphonuclears (PMN) and alveolar macrophages (AM) in the lung of dog with fat tissue extract induced respiratory distress syndrome (RDS)." | 7.69 | [Effects of pentoxifylline on leukocyte in the lungs of dog with fat tissue extract-induced respiratory distress syndrome]. ( Guo, XJ; Mao, BL; Xu, JC, 1994) |
| "We examined effects of early post-treatment with pentoxifylline (PTX) on fat tissue extract (FTE) induced respiratory distress syndrome in dogs." | 7.69 | [Effect of pentoxifylline on respiratory distress syndrome in dogs]. ( Guo, XJ; Mao, BL; Xu, JC, 1994) |
| "We investigated the effect of pentoxifylline (PTX) on the development of pulmonary edema in a model of adult respiratory distress syndrome in rabbits." | 7.68 | Effect of pentoxifylline on hemodynamics, alveolar fluid reabsorption, and pulmonary edema in a model of acute lung injury. ( Hannam, VL; Kaapa, P; O'Brodovich, HM; Raj, JU; Seear, MD, 1990) |
| "In this study 30 advanced cancer patients with ARDS were randomized to receive either the conventional care or conventional care plus PTX (100 mg i." | 6.67 | Respiratory distress syndrome in patients with advanced cancer treated with pentoxifylline: a randomized study. ( Ardizzoia, A; Barni, S; Crispino, S; Lissoni, P; Paolorossi, F; Tancini, G; Villa, S, 1993) |
| "Caerulein-induced acute pancreatitis in rats commonly complicated ARDS-like acute lung injury." | 5.29 | [The role of pentoxifylline in acute lung injury complicated by pancreatitis]. ( Deng, WW; Huang, SG; Peng, XX, 1994) |
| "Pentoxifylline (PTX) has been shown in vitro to protect against the inflammatory effects of neutrophils and cytokines." | 5.29 | Pilot study of cardiopulmonary risk from pentoxifylline in adult respiratory distress syndrome. ( Blanchet, F; Chastre, J; Fagon, JY; Gilbert, C; Montravers, P; Novara, A, 1993) |
| "Pentoxifylline is a methylxanthine interacting with the biology of several types of cells, including red blood cells, neutrophils, blood monocytes, and endothelial cells." | 5.29 | In vitro effects of pentoxifylline on smooth muscle cell migration and blood monocyte production of chemotactic activity for smooth muscle cells: potential therapeutic benefit in the adult respiratory distress syndrome. ( Kullmann, A; Martinet, N; Martinet, Y; Muller, V; Vaillant, P, 1993) |
| "To determine whether the administration of lisofylline (1-[5R-hydroxyhexyl]-3,7-dimethylxanthine) would decrease mortality in patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS)." | 5.10 | Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome. ( , 2002) |
| " Even in developed countries, the occurrence of spontaneous air-leaks and acute respiratory distress syndrome (ARDS) still represent the most severe clinical presentation in early childhood, with a high fatality rate." | 3.76 | Measles-induced respiratory distress, air-leak and ARDS. ( Conti, G; De Luca, D; De Rosa, G; Lancella, L; Marzano, L; Onesimo, R; Piastra, M; Pietrini, D; Valentini, P, 2010) |
| " Resuscitation with hypertonic saline and pentoxifylline (HSPTX) has been shown to attenuate hemorrhagic shock-induced injury when compared with RL." | 3.74 | Hypertonic saline and pentoxifylline reduces hemorrhagic shock resuscitation-induced pulmonary inflammation through attenuation of neutrophil degranulation and proinflammatory mediator synthesis. ( Coimbra, R; de Campos, T; Deree, J; Hoyt, DB; Lamon, B; Leedom, A; Martins, JO; Putnam, J; Wolf, P, 2007) |
| " We hypothesized that the anti-inflammatory agent pentoxifylline (PTX) attenuates postresuscitative lung injury through modulation of transcription factors after hemorrhagic shock." | 3.74 | Pentoxifylline attenuates lung injury and modulates transcription factor activity in hemorrhagic shock. ( Coimbra, R; de Campos, T; Deree, J; Loomis, WH; Martins, J; Putnam, JG; Wolf, P, 2007) |
| "To assess the effects of pentoxifylline posttreatment on hemodynamic variables and acute pulmonary injury in the rat intestinal ischemia-reperfusion (I-R) model, using a recently developed method of fluorescent intravital pulmonary videomicroscopy." | 3.69 | Pentoxifylline attenuates pulmonary macromolecular leakage after intestinal ischemia-reperfusion. ( Carter, MB; Garrison, RN; Wead, WB; Wilson, MA, 1995) |
| "We studied the effects of pentoxifylline (PTX) on the polymorphonuclears (PMN) and alveolar macrophages (AM) in the lung of dog with fat tissue extract induced respiratory distress syndrome (RDS)." | 3.69 | [Effects of pentoxifylline on leukocyte in the lungs of dog with fat tissue extract-induced respiratory distress syndrome]. ( Guo, XJ; Mao, BL; Xu, JC, 1994) |
| "We examined effects of early post-treatment with pentoxifylline (PTX) on fat tissue extract (FTE) induced respiratory distress syndrome in dogs." | 3.69 | [Effect of pentoxifylline on respiratory distress syndrome in dogs]. ( Guo, XJ; Mao, BL; Xu, JC, 1994) |
| "We investigated the effect of pentoxifylline (PTX) on the development of pulmonary edema in a model of adult respiratory distress syndrome in rabbits." | 3.68 | Effect of pentoxifylline on hemodynamics, alveolar fluid reabsorption, and pulmonary edema in a model of acute lung injury. ( Hannam, VL; Kaapa, P; O'Brodovich, HM; Raj, JU; Seear, MD, 1990) |
| "No significant degree of pulmonary sequestration was detected in any measurements after protamine was administered in the aprotinin and pentoxifylline (PTX) groups." | 2.71 | The importance of aprotinin and pentoxifylline in preventing leukocyte sequestration and lung injury caused by protamine at the end of cardiopulmonary bypass surgery. ( Arar, C; Canbaz, S; Cikirikcioglu, M; Duran, E; Ege, T; Sunar, H; Yuksel, V, 2004) |
| "No means exist for predicting the acute respiratory distress syndrome (ARDS), which complicates sepsis, trauma, and a variety of clinical disorders." | 2.68 | An increase in serum C18 unsaturated free fatty acids as a predictor of the development of acute respiratory distress syndrome. ( Abraham, E; Bianco, JA; Bursten, SL; Federighi, DA; Harris, WE; Moore, EE; Moore, FA; Parsons, P; Repine, JE; Singer, JW, 1996) |
| "In this study 30 advanced cancer patients with ARDS were randomized to receive either the conventional care or conventional care plus PTX (100 mg i." | 2.67 | Respiratory distress syndrome in patients with advanced cancer treated with pentoxifylline: a randomized study. ( Ardizzoia, A; Barni, S; Crispino, S; Lissoni, P; Paolorossi, F; Tancini, G; Villa, S, 1993) |
| "We postulated that PTX treatment in acute endotoxemia downregulates the inflammatory response and may decrease lung injury." | 1.33 | LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition: effects on proinflammatory mediators, metalloproteinases, NF-kappaB, and ICAM-1 expression. ( Coimbra, R; Hoyt, DB; Loomis, W; Melbostad, H; Porcides, RD; Tobar, M; Wolf, P, 2006) |
| "Venous air embolism increases the pulmonary arterial pressure and the vascular permeability leading to acute lung injury." | 1.30 | Dibutyryl cAMP prevents increased vascular permeability caused by air embolism in isolated rat lungs. ( Chiang, CH; Hsu, CS; Hsu, K; Huang, KL; Wang, D, 1997) |
| " After 6 hr, dose-response curves to ACh, A23187, and SNP were determined in isolated pulmonary artery rings preconstricted with phenylephrine (PE)." | 1.30 | Pentoxifylline treatment attenuates pulmonary vasomotor dysfunction in acute lung injury. ( Fullerton, DA; McIntyre, RC; Meldrum, DR; Sheridan, BC, 1997) |
| "Pentoxifylline is a noteworthy drug that could be a candidate as a therapy to help prevent hypoxemia in lung injuries that share a common mechanism with oleic acid-induced lung injury." | 1.29 | Pentoxifylline prevents a decrease in arterial oxygen tension in oleic acid-induced lung injury. ( Moriuchi, H; Yuizono, T, 1995) |
| "Hyperoxia has been used extensively as a model of acute lung injury." | 1.29 | Pentoxifylline does not protect against hyperoxic lung injury in rats. ( Benjaminov, O; Factor, P; Hoffer, E; Naureckas, ET; Sriram, V; Sznajder, JI, 1994) |
| "Caerulein-induced acute pancreatitis in rats commonly complicated ARDS-like acute lung injury." | 1.29 | [The role of pentoxifylline in acute lung injury complicated by pancreatitis]. ( Deng, WW; Huang, SG; Peng, XX, 1994) |
| "Indomethacin was able to completely block the cytokine-induced decrease in PC synthesis by pneumocytes from the malignant group and to attenuate the inhibitory effect of TNF alpha in those from donors, nordihydroguaiaretic acid having a similar effect." | 1.29 | Tumor necrosis factor-alpha-induced inhibition of phosphatidylcholine synthesis by human type II pneumocytes is partially mediated by prostaglandins. ( Arias-Díaz, J; Balibrea, JL; García, C; Vara, E, 1994) |
| "Pentoxifylline (PTX) has been shown in vitro to protect against the inflammatory effects of neutrophils and cytokines." | 1.29 | Pilot study of cardiopulmonary risk from pentoxifylline in adult respiratory distress syndrome. ( Blanchet, F; Chastre, J; Fagon, JY; Gilbert, C; Montravers, P; Novara, A, 1993) |
| "Pentoxifylline is a methylxanthine interacting with the biology of several types of cells, including red blood cells, neutrophils, blood monocytes, and endothelial cells." | 1.29 | In vitro effects of pentoxifylline on smooth muscle cell migration and blood monocyte production of chemotactic activity for smooth muscle cells: potential therapeutic benefit in the adult respiratory distress syndrome. ( Kullmann, A; Martinet, N; Martinet, Y; Muller, V; Vaillant, P, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.38) | 18.7374 |
| 1990's | 28 (66.67) | 18.2507 |
| 2000's | 9 (21.43) | 29.6817 |
| 2010's | 3 (7.14) | 24.3611 |
| 2020's | 1 (2.38) | 2.80 |
| Authors | Studies |
|---|---|
| Assimakopoulos, SF | 1 |
| Seintis, F | 1 |
| Marangos, M | 1 |
| Jung, HS | 1 |
| Kaplan, LJ | 1 |
| Park, PK | 1 |
| Li, Q | 1 |
| Hu, X | 1 |
| Sun, R | 1 |
| Tu, Y | 1 |
| Gong, F | 1 |
| Ni, Y | 1 |
| Piastra, M | 1 |
| Onesimo, R | 1 |
| De Luca, D | 1 |
| Lancella, L | 1 |
| Marzano, L | 1 |
| De Rosa, G | 1 |
| Pietrini, D | 1 |
| Valentini, P | 1 |
| Conti, G | 1 |
| Oliveira-Junior, IS | 1 |
| Pinheiro, BV | 1 |
| Silva, ID | 1 |
| Salomão, R | 1 |
| Zollner, RL | 1 |
| Beppu, OS | 1 |
| Wiedemann, HP | 1 |
| Arroliga, AC | 1 |
| Komara, JJ | 1 |
| Ege, T | 1 |
| Arar, C | 1 |
| Canbaz, S | 1 |
| Cikirikcioglu, M | 1 |
| Sunar, H | 1 |
| Yuksel, V | 1 |
| Duran, E | 1 |
| Adhikari, N | 1 |
| Burns, KE | 1 |
| Meade, MO | 1 |
| Coimbra, R | 3 |
| Melbostad, H | 1 |
| Loomis, W | 1 |
| Porcides, RD | 1 |
| Wolf, P | 3 |
| Tobar, M | 1 |
| Hoyt, DB | 2 |
| Deree, J | 2 |
| Martins, JO | 1 |
| Leedom, A | 1 |
| Lamon, B | 1 |
| Putnam, J | 1 |
| de Campos, T | 2 |
| Martins, J | 1 |
| Putnam, JG | 1 |
| Loomis, WH | 1 |
| Carter, MB | 1 |
| Wilson, MA | 1 |
| Wead, WB | 1 |
| Garrison, RN | 1 |
| Shen, CY | 1 |
| Hsu, K | 2 |
| Wang, D | 2 |
| Yan, HC | 1 |
| Balázs, C | 1 |
| Kiss, E | 1 |
| Moriuchi, H | 1 |
| Yuizono, T | 1 |
| Xu, JC | 2 |
| Guo, XJ | 2 |
| Mao, BL | 2 |
| Zabel, P | 1 |
| Schade, FU | 1 |
| Naureckas, ET | 1 |
| Factor, P | 1 |
| Benjaminov, O | 1 |
| Hoffer, E | 1 |
| Sriram, V | 1 |
| Sznajder, JI | 1 |
| Peng, XX | 1 |
| Deng, WW | 1 |
| Huang, SG | 1 |
| Arias-Díaz, J | 2 |
| Vara, E | 2 |
| García, C | 2 |
| Balibrea, JL | 1 |
| Balibrea-Cantero, JL | 1 |
| Torres-Melero, J | 1 |
| Simon, C | 1 |
| Rodriguez, JM | 1 |
| Montravers, P | 1 |
| Fagon, JY | 1 |
| Gilbert, C | 1 |
| Blanchet, F | 1 |
| Novara, A | 1 |
| Chastre, J | 1 |
| Sulkowski, S | 1 |
| Ejsmont-Pietrow, G | 1 |
| Musiatowicz, B | 1 |
| Sulkowska, M | 2 |
| Ardizzoia, A | 1 |
| Lissoni, P | 1 |
| Tancini, G | 1 |
| Paolorossi, F | 1 |
| Crispino, S | 1 |
| Villa, S | 1 |
| Barni, S | 1 |
| Kullmann, A | 1 |
| Vaillant, P | 1 |
| Muller, V | 1 |
| Martinet, Y | 1 |
| Martinet, N | 1 |
| Hoffmann, H | 1 |
| Weis, M | 1 |
| Frank, G | 1 |
| Birg, A | 1 |
| Schönharting, MM | 1 |
| Jochum, M | 1 |
| Bursten, SL | 1 |
| Federighi, DA | 1 |
| Parsons, P | 1 |
| Harris, WE | 1 |
| Abraham, E | 1 |
| Moore, EE | 1 |
| Moore, FA | 1 |
| Bianco, JA | 1 |
| Singer, JW | 1 |
| Repine, JE | 1 |
| Krafft, P | 1 |
| Fridrich, P | 1 |
| Hammerle, AF | 1 |
| Steltzer, H | 1 |
| Hasegawa, N | 1 |
| Oka, Y | 1 |
| Nakayama, M | 1 |
| Berry, GJ | 1 |
| Bursten, S | 1 |
| Rice, G | 1 |
| Raffin, TA | 1 |
| Huang, KL | 1 |
| Hsu, CS | 1 |
| Chiang, CH | 1 |
| Sheridan, BC | 1 |
| McIntyre, RC | 1 |
| Meldrum, DR | 1 |
| Fullerton, DA | 1 |
| Butler, J | 1 |
| Baigrie, RJ | 1 |
| Parker, D | 1 |
| Chong, JL | 1 |
| Shale, DJ | 1 |
| Pillai, R | 1 |
| Westaby, S | 1 |
| Rocker, GM | 1 |
| Lynch, RE | 1 |
| Tuckey, JA | 1 |
| Parry, BR | 1 |
| McCall, JL | 1 |
| Ambrus, JL | 1 |
| Halpern, J | 1 |
| Mahafzah, M | 1 |
| Sayyid, S | 1 |
| Seear, MD | 1 |
| Hannam, VL | 1 |
| Kaapa, P | 1 |
| Raj, JU | 1 |
| O'Brodovich, HM | 1 |
| Sarma, PS | 1 |
| Keogh, BF | 1 |
| Hunter, DN | 1 |
| Morgan, CJ | 1 |
| Evans, TW | 1 |
| Mandell, GL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| HYPERTONIC SALINE COATED FACE MASK FOR REDUCING RESPIRATORY SYMPTOM SEVERITY IN PATIENTS WITH COVID-19[NCT04465604] | 50 participants (Anticipated) | Interventional | 2021-02-01 | Recruiting | |||
| INFLACOR (INFLA-mmation A-fter C-ardiac O-pe-R-ation) - Use of Selected Genetic Variants, Cytokines, and Physiologic Parameters in the Prognosis of Postoperative Complications in Patients Undergoing Cardiopulmonary Bypass Cardiac Surgery[NCT01020409] | 525 participants (Actual) | Observational | 2009-10-31 | Completed | |||
| Acute Respiratory Distress Syndrome Clinical Network (ARDSNet)[NCT00000579] | Phase 3 | 0 participants | Interventional | 1994-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for pentoxifylline and Respiratory Distress Syndrome
| Article | Year |
|---|---|
Reviewing the studies of the National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network: outcomes and clinical findings.
Topics: Acute Lung Injury; Albuterol; Anti-Inflammatory Agents, Non-Steroidal; Bronchodilator Agents; Dietar | 2013 |
Emerging systemic pharmacologic approaches in acute respiratory distress syndrome.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antioxidants; Atrial Natriuretic Factor; Humans; | 2003 |
Pharmacologic treatments for acute respiratory distress syndrome and acute lung injury: systematic review and meta-analysis.
Topics: Acetylcysteine; Adrenal Cortex Hormones; Alprostadil; Humans; Pentoxifylline; Randomized Controlled | 2004 |
Immunological aspects of the effect of pentoxifylline (Trental) (a brief review).
Topics: Animals; Cytokines; HIV Infections; Humans; Immune System; In Vitro Techniques; Neoplasms; Pentoxify | 1994 |
[Role of pentoxifylline in prevention and treatment of adult respiratory distress syndrome].
Topics: Animals; Humans; Pentoxifylline; Respiratory Distress Syndrome | 1993 |
Methylxanthines in surgery: a bright future?
Topics: Humans; Neoplasms; Pentoxifylline; Respiratory Distress Syndrome; Shock, Septic; Surgical Procedures | 1992 |
The management of adult respiratory distress syndrome: 2.
Topics: Adult; Extracorporeal Membrane Oxygenation; High-Frequency Jet Ventilation; Humans; Immunologic Fact | 1990 |
ARDS, neutrophils, and pentoxifylline.
Topics: Animals; Biological Factors; Cytokines; Endotoxins; Humans; Neutrophils; Pentoxifylline; Respiratory | 1988 |
6 trials available for pentoxifylline and Respiratory Distress Syndrome
| Article | Year |
|---|---|
The importance of aprotinin and pentoxifylline in preventing leukocyte sequestration and lung injury caused by protamine at the end of cardiopulmonary bypass surgery.
Topics: Aged; Aprotinin; Biomarkers; Blood Pressure; Bronchopulmonary Sequestration; Cardiac Output; Cardiop | 2004 |
Respiratory distress syndrome in patients with advanced cancer treated with pentoxifylline: a randomized study.
Topics: Administration, Oral; Adult; Aged; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neopla | 1993 |
An increase in serum C18 unsaturated free fatty acids as a predictor of the development of acute respiratory distress syndrome.
Topics: Adult; Double-Blind Method; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Female; Humans; Ma | 1996 |
Systemic inflammatory responses to cardiopulmonary bypass: a pilot study of the effects of pentoxifylline.
Topics: alpha 1-Antitrypsin; Cardiopulmonary Bypass; Cell Movement; Coronary Artery Bypass; Elective Surgica | 1993 |
Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Fatty Acids, Nonesterified; Humans; In | 2002 |
Pentoxifylline in septic shock.
Topics: Adult; Female; Humans; Male; Middle Aged; Pentoxifylline; Prospective Studies; Respiratory Distress | 1990 |
28 other studies available for pentoxifylline and Respiratory Distress Syndrome
| Article | Year |
|---|---|
Pentoxifylline and complicated COVID-19: A pathophysiologically based treatment proposal.
Topics: Antibodies, Monoclonal, Humanized; Betacoronavirus; Blood Coagulation Disorders; Coronavirus Infecti | 2020 |
Resolution acute respiratory distress syndrome through reversing the imbalance of Treg/Th17 by targeting the cAMP signaling pathway.
Topics: Animals; Cyclic AMP; Cytokines; Disease Models, Animal; Forkhead Transcription Factors; Gene Express | 2016 |
Measles-induced respiratory distress, air-leak and ARDS.
Topics: Bronchiolitis; Child, Preschool; Disease Outbreaks; Female; Humans; Iloprost; Infant; Intensive Care | 2010 |
Pentoxifylline decreases tumor necrosis factor and interleukin-1 during high tidal volume.
Topics: Animals; Blood Gas Analysis; Bronchoalveolar Lavage; Interleukin-1; Lung Volume Measurements; Male; | 2003 |
LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition: effects on proinflammatory mediators, metalloproteinases, NF-kappaB, and ICAM-1 expression.
Topics: Animals; Disease Models, Animal; Endotoxemia; Escherichia coli Infections; Intercellular Adhesion Mo | 2006 |
Hypertonic saline and pentoxifylline reduces hemorrhagic shock resuscitation-induced pulmonary inflammation through attenuation of neutrophil degranulation and proinflammatory mediator synthesis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Degranulation; Enzyme-Linked Immunosorbent Assay; Fluid | 2007 |
Pentoxifylline attenuates lung injury and modulates transcription factor activity in hemorrhagic shock.
Topics: Animals; Anti-Inflammatory Agents; Chemokine CXCL1; Disease Models, Animal; Heme Oxygenase-1; Isoton | 2007 |
Pentoxifylline attenuates pulmonary macromolecular leakage after intestinal ischemia-reperfusion.
Topics: Animals; Blood-Air Barrier; Cardiac Output; Disease Models, Animal; Hemodynamics; Intestines; Ischem | 1995 |
Pentoxifylline attenuates acute lung injury induced by microemboli.
Topics: Acute Disease; Animals; Blood Platelets; Blood Pressure; Bronchoalveolar Lavage Fluid; Calcium Chlor | 1995 |
Pentoxifylline prevents a decrease in arterial oxygen tension in oleic acid-induced lung injury.
Topics: Airway Resistance; Animals; Blood Pressure; Capillary Permeability; Carbon Dioxide; Guinea Pigs; Hyd | 1995 |
[Effects of pentoxifylline on leukocyte in the lungs of dog with fat tissue extract-induced respiratory distress syndrome].
Topics: Animals; Bronchoalveolar Lavage Fluid; Dogs; Interleukin-1; Leukocyte Count; Macrophages, Alveolar; | 1994 |
Pentoxifylline and tumour necrosis factor-induced lung injury.
Topics: Animals; Hyperoxia; Pentoxifylline; Respiratory Distress Syndrome; Tumor Necrosis Factor-alpha | 1994 |
Pentoxifylline does not protect against hyperoxic lung injury in rats.
Topics: Animals; Cell Movement; Hyperoxia; Lung; Male; Neutrophils; Pentoxifylline; Rats; Rats, Sprague-Dawl | 1994 |
[Effect of pentoxifylline on respiratory distress syndrome in dogs].
Topics: Adipose Tissue; Animals; Dogs; Female; Male; Pentoxifylline; Respiratory Distress Syndrome | 1994 |
[The role of pentoxifylline in acute lung injury complicated by pancreatitis].
Topics: Animals; Capillary Permeability; Ceruletide; Free Radicals; Male; Neutrophils; Pancreatitis; Pentoxi | 1994 |
Tumor necrosis factor-alpha-induced inhibition of phosphatidylcholine synthesis by human type II pneumocytes is partially mediated by prostaglandins.
Topics: Adult; Age Factors; Arachidonic Acid; Humans; In Vitro Techniques; Indomethacin; Lung; Male; Middle | 1994 |
Effect of pentoxifylline on the inhibition of surfactant synthesis induced by TNF-alpha in human type II pneumocytes.
Topics: Adult; Analysis of Variance; Drug Evaluation, Preclinical; Humans; In Vitro Techniques; Lung; Lung N | 1994 |
Pilot study of cardiopulmonary risk from pentoxifylline in adult respiratory distress syndrome.
Topics: Aged; Hemodynamics; Humans; Middle Aged; Pentoxifylline; Pilot Projects; Pulmonary Gas Exchange; Res | 1993 |
In vitro effects of pentoxifylline on smooth muscle cell migration and blood monocyte production of chemotactic activity for smooth muscle cells: potential therapeutic benefit in the adult respiratory distress syndrome.
Topics: Blood Platelets; Cell Division; Cell Extracts; Cells, Cultured; Chemotactic Factors; Chemotaxis; Fib | 1993 |
Amelioration of endotoxin-induced acute lung injury in pigs by HWA 138 and A 80 2715: new analogs of pentoxifylline.
Topics: Animals; Bronchodilator Agents; Hemodynamics; Infusions, Intravenous; Leukocyte Count; Leukopenia; L | 1995 |
Supportive pharmacotherapy for patients with acute respiratory distress syndrome.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Glucocorticoids; Human | 1996 |
The effects of post-treatment with lisofylline, a phosphatidic acid generation inhibitor, on sepsis-induced acute lung injury in pigs.
Topics: Adjuvants, Immunologic; Animals; Disease Models, Animal; Female; Hemodynamics; Lung; Male; Pentoxify | 1997 |
Dibutyryl cAMP prevents increased vascular permeability caused by air embolism in isolated rat lungs.
Topics: Aerospace Medicine; Aminophylline; Animals; Bronchodilator Agents; Bucladesine; Capillary Permeabili | 1997 |
Pentoxifylline treatment attenuates pulmonary vasomotor dysfunction in acute lung injury.
Topics: Animals; Endothelium, Vascular; Endotoxins; Male; Nitroprusside; Pentoxifylline; Phosphodiesterase I | 1997 |
Effect of human recombinant tumour necrosis factor-alpha and pentoxifylline on the ultrastructure of type II alveolar epithelial cells in pregnant and non-pregnant rabbits.
Topics: Animals; Disease Models, Animal; Epithelial Cells; Female; Humans; Microscopy, Electron; Pentoxifyll | 1997 |
Lisofylline: anti-acute respiratory distress syndrome or just anti-inflammatory?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Lung Diseases; Pentoxifylline; Respiratory Distress | 2002 |
Platelet aggregation in septic shock. Effect of pentoxifylline.
Topics: Adult; Aged; Humans; Middle Aged; Pentoxifylline; Platelet Aggregation; Reference Values; Respirator | 1990 |
Effect of pentoxifylline on hemodynamics, alveolar fluid reabsorption, and pulmonary edema in a model of acute lung injury.
Topics: Absorption; Acute Disease; Animals; Capillary Permeability; Extravascular Lung Water; Hemodynamics; | 1990 |