Page last updated: 2024-11-02

pentoxifylline and Pulmonary Sarcoidosis

pentoxifylline has been researched along with Pulmonary Sarcoidosis in 8 studies

Research Excerpts

ExcerptRelevanceReference
"Pentoxifylline (POF) has recently been shown to suppress the cytokine production from lipopolysaccharide (LPS) stimulated monocytes/alveolar macrophages (AM)."5.32[Inhibition of cytokine release from alveolar macrophages in pulmonary sarcoidosis by pentoxifylline]. ( Chen, BM; Costabel, U; Dai, HP; Guzman, J; Tong, ZH; Wang, C, 2003)
"Pentoxifylline (POF) has been shown to suppress the cytokine production from lipopolysaccharide (LPS)-stimulated monocytes/alveolar macrophages (AMs)."5.32Inhibition of cytokine release from alveolar macrophages in pulmonary sarcoidosis by pentoxifylline: comparison with dexamethasone. ( Abdoh, Z; Chen, B; Costabel, U; Dai, H; Guzman, J; Tong, Z, 2003)
" Because tumor necrosis factor alpha (TNF) plays a critical role in granuloma formation and sustenance as well as in the progression of sarcoidosis, we investigated pentoxifylline (POF), which exerts TNF-inhibitory activity, as a therapeutic agent in active pulmonary sarcoidosis."3.69Pentoxifylline in treatment of sarcoidosis. ( Dalhoff, K; Entzian, P; Schlaak, M; Zabel, P, 1997)
"Pentoxifylline (POF) has recently been shown to suppress the cytokine production from lipopolysaccharide (LPS) stimulated monocytes/alveolar macrophages (AM)."1.32[Inhibition of cytokine release from alveolar macrophages in pulmonary sarcoidosis by pentoxifylline]. ( Chen, BM; Costabel, U; Dai, HP; Guzman, J; Tong, ZH; Wang, C, 2003)
"Pentoxifylline (POF) has been shown to suppress the cytokine production from lipopolysaccharide (LPS)-stimulated monocytes/alveolar macrophages (AMs)."1.32Inhibition of cytokine release from alveolar macrophages in pulmonary sarcoidosis by pentoxifylline: comparison with dexamethasone. ( Abdoh, Z; Chen, B; Costabel, U; Dai, H; Guzman, J; Tong, Z, 2003)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's5 (62.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bargagli, E1
Olivieri, C1
Rottoli, P1
Mrazek, F1
Sekerova, V1
Drabek, J1
Kolek, V1
du Bois, RM1
Petrek, M1
Tong, ZH1
Dai, HP1
Chen, BM1
Wang, C1
Guzman, J3
Costabel, U3
Tong, Z1
Dai, H1
Chen, B1
Abdoh, Z1
Inoue, K1
Takano, H1
Yanagisawa, R1
Sakurai, M1
Paramothayan, S1
Lasserson, TJ1
Walters, EH1
Zabel, P1
Entzian, P1
Dalhoff, K1
Schlaak, M1
Marques, LJ1
Zheng, L1
Poulakis, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Pulmonary Sarcoidosis With Pentoxifylline[NCT00001877]Phase 2100 participants Interventional1999-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for pentoxifylline and Pulmonary Sarcoidosis

ArticleYear
Cytokine modulators in the treatment of sarcoidosis.
    Rheumatology international, 2011, Volume: 31, Issue:12

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; C

2011
Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis.
    The Cochrane database of systematic reviews, 2006, Jul-19, Issue:3

    Topics: Antineoplastic Agents; Chloroquine; Cyclosporine; Humans; Immunosuppressive Agents; Methotrexate; Pe

2006

Other Studies

6 other studies available for pentoxifylline and Pulmonary Sarcoidosis

ArticleYear
Expression of the chemokine PARC mRNA in bronchoalveolar cells of patients with sarcoidosis.
    Immunology letters, 2002, Oct-21, Volume: 84, Issue:1

    Topics: Adjuvants, Immunologic; Adult; Aged; Base Sequence; Bronchoalveolar Lavage Fluid; Cell Count; Chemok

2002
[Inhibition of cytokine release from alveolar macrophages in pulmonary sarcoidosis by pentoxifylline].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2003, Volume: 26, Issue:7

    Topics: Adult; Cytokines; Dexamethasone; Female; Humans; Lipopolysaccharides; Macrophages, Alveolar; Male; M

2003
Inhibition of cytokine release from alveolar macrophages in pulmonary sarcoidosis by pentoxifylline: comparison with dexamethasone.
    Chest, 2003, Volume: 124, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Cytokines; Dexamethasone; Female; Humans; Macrophages, Alveolar; Ma

2003
Anti-inflammatory Effect of Pentoxifylline.
    Chest, 2004, Volume: 126, Issue:1

    Topics: Anti-Inflammatory Agents; Cytokines; Humans; Immunity, Cellular; Pentoxifylline; Sarcoidosis, Pulmon

2004
Pentoxifylline in treatment of sarcoidosis.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:5

    Topics: Adult; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Male; Pentoxifylline; Phosphodies

1997
Pentoxifylline inhibits TNF-alpha production from human alveolar macrophages.
    American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:2

    Topics: Adult; Biomarkers; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent As

1999