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pentoxifylline and Pulmonary Hypertension

pentoxifylline has been researched along with Pulmonary Hypertension in 8 studies

Research Excerpts

ExcerptRelevanceReference
"Inhalation of aerosolized iloprost, a stable prostacyclin analog, has been suggested for treatment of primary and secondary pulmonary hypertension, but demands multiple daily inhalation maneuvers because of the short-term effect of this approach."7.71Coaerosolization of phosphodiesterase inhibitors markedly enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension. Maintenance of lung selectivity. ( Ghofrani, HA; Grimminger, F; Krupnik, E; Rose, F; Schermuly, RT; Schudt, C; Seeger, W; Tenor, H; Walmrath, D; Weissmann, N, 2001)
"Inhalation of aerosolized iloprost, a stable prostacyclin analog, has been suggested for treatment of primary and secondary pulmonary hypertension, but demands multiple daily inhalation maneuvers because of the short-term effect of this approach."3.71Coaerosolization of phosphodiesterase inhibitors markedly enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension. Maintenance of lung selectivity. ( Ghofrani, HA; Grimminger, F; Krupnik, E; Rose, F; Schermuly, RT; Schudt, C; Seeger, W; Tenor, H; Walmrath, D; Weissmann, N, 2001)
" Thromboxane A2 is the major mediator of the early pulmonary hypertension associated with endotoxemia, but the mechanisms underlying the prolonged hemodynamic disturbances observed in ongoing endotoxemia are not well understood."3.69Delayed thromboxane or tumor necrosis factor-alpha, but not leukotriene inhibition, attenuates prolonged pulmonary hypertension in endotoxemia. ( Li, JX; Lu, CY; Oliver, JR; Philips, JB, 1995)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's5 (62.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, MK1
Babaali, H1
Gilbert-McClain, LI1
Stylianou, M1
Joo, J1
Moss, J1
Manganiello, VC1
Li, JX1
Oliver, JR1
Lu, CY1
Philips, JB1
Lauterbach, R1
Manohar, M2
Goetz, TE2
Rothenbaum, P2
Humphrey, S2
Schermuly, RT2
Roehl, A1
Weissmann, N2
Ghofrani, HA2
Leuchte, H1
Grimminger, F2
Seeger, W2
Walmrath, D2
Krupnik, E1
Tenor, H1
Schudt, C1
Rose, F1
Truog, WE1
Gibson, RL1
Henderson, WR1
Redding, GJ1
Standaert, TA1

Trials

1 trial available for pentoxifylline and Pulmonary Hypertension

ArticleYear
Steroid-sparing effects of pentoxifylline in pulmonary sarcoidosis.
    Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2009, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Aged; Biopsy; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forc

2009

Other Studies

7 other studies available for pentoxifylline and Pulmonary Hypertension

ArticleYear
Delayed thromboxane or tumor necrosis factor-alpha, but not leukotriene inhibition, attenuates prolonged pulmonary hypertension in endotoxemia.
    The American journal of the medical sciences, 1995, Volume: 310, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Female; Hemodynamics; Humans; Hypertension, Pulmo

1995
Pentoxifylline treatment of persistent pulmonary hypertension of newborn.
    European journal of pediatrics, 1993, Volume: 152, Issue:5

    Topics: Chronic Disease; Humans; Hypertension, Pulmonary; Infant, Newborn; Infant, Premature, Diseases; Pent

1993
Intravenous pentoxifylline does not affect the exercise-induced pulmonary arterial, capillary or venous hypertension in Thoroughbred horses.
    Journal of veterinary pharmacology and therapeutics, 2000, Volume: 23, Issue:5

    Topics: Animals; Breeding; Female; Hemodynamics; Horse Diseases; Horses; Hypertension, Pulmonary; Injections

2000
Intravenous pentoxifylline does not enhance the pulmonary haemodynamic efficacy of frusemide in strenuously exercising thoroughbred horses.
    Equine veterinary journal, 2001, Volume: 33, Issue:4

    Topics: Animals; Breeding; Diuretics; Drug Administration Schedule; Drug Interactions; Female; Furosemide; H

2001
Combination of nonspecific PDE inhibitors with inhaled prostacyclin in experimental pulmonary hypertension.
    American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 281, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Anim

2001
Coaerosolization of phosphodiesterase inhibitors markedly enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension. Maintenance of lung selectivity.
    American journal of respiratory and critical care medicine, 2001, Nov-01, Volume: 164, Issue:9

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aerosols; Animals; Dipyridamole;

2001
Effect of pentoxifylline on cytokine- and eicosanoid-induced acute pulmonary hypertension in piglets.
    Pediatric research, 1992, Volume: 31, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acute Disease; Animals; Animals,

1992