pentoxifylline has been researched along with Poliomyelitis in 2 studies
Poliomyelitis: An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentoxifylline (PTX) has been recently shown to have a variety of immunomodulatory effects." | 1.30 | The effect of pentoxifylline (PTX) on Theiler's murine encephalomyelitis (TMEV)-induced demyelinating disease. ( Fushimi, T; Inoue, A; Ishihara, Y; Kim, BS; Koh, CS; Yamazaki, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Campagnola, G | 1 |
| Gong, P | 1 |
| Peersen, OB | 1 |
| Fushimi, T | 1 |
| Inoue, A | 1 |
| Koh, CS | 1 |
| Yamazaki, M | 1 |
| Ishihara, Y | 1 |
| Kim, BS | 1 |
2 other studies available for pentoxifylline and Poliomyelitis
| Article | Year |
|---|---|
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
Topics: Allosteric Regulation; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; F | 2011 |
The effect of pentoxifylline (PTX) on Theiler's murine encephalomyelitis (TMEV)-induced demyelinating disease.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Viral; Cell Division; Cell Line; Crice | 1998 |