Page last updated: 2024-11-02

pentoxifylline and Pneumonia

pentoxifylline has been researched along with Pneumonia in 11 studies

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"Pentoxifylline is a TNFα inhibitor known to suppress inflammation."5.40Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation. ( Cervelli, JA; Gow, AJ; Hall, L; Laskin, DL; Laskin, JD; Malaviya, R; Massa, CB; Sunil, VR; Vayas, KN, 2014)
"These results indicate that meconium aspiration induces severe inflammation in the lung."5.38The effects of pentoxifylline on lung inflammation in a rat model of meconium aspiration syndrome. ( Atıcı, A; Helvacı, İ; Muşlu, N; Polat, A; Turhan, AH, 2012)
"Pentoxifylline (PTX) has been shown to attenuate neutrophil activation and end-organ injury in shock states such as hemorrhage and sepsis."5.35Pentoxifylline attenuates pulmonary inflammation and neutrophil activation in experimental acute pancreatitis. ( Coimbra, R; de Campos, T; Deree, J; Loomis, WH; Martins, JO; Putnam, JG; Shenvi, E, 2008)
"Pentoxifylline (PTX) has been shown to reduce sepsis-induced neutrophil sequestration in the lung and inhibit endotoxin-mediated release of tumor necrosis factor-alpha (TNF-alpha)."2.68Pentoxifylline does not alter the response to inhaled grain dust. ( Jagielo, PJ; Knapp, HR; Quinn, TJ; Schwartz, DA; Watt, JL, 1997)
"Counterproductive lung inflammation and dysregulated thrombosis contribute importantly to the lethality of advanced COVID-19."1.56Harnessing adenosine A2A receptors as a strategy for suppressing the lung inflammation and thrombotic complications of COVID-19: Potential of pentoxifylline and dipyridamole. ( Barroso-Aranda, J; DiNicolantonio, JJ, 2020)
"Pentoxifylline is a TNFα inhibitor known to suppress inflammation."1.40Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation. ( Cervelli, JA; Gow, AJ; Hall, L; Laskin, DL; Laskin, JD; Malaviya, R; Massa, CB; Sunil, VR; Vayas, KN, 2014)
"Pentoxifylline (PTX) has been shown to exert anti-inflammatory effects in experimental acute lung injury."1.39Protective effects of pentoxifylline in pulmonary inflammation are adenosine receptor A2A dependent. ( Konrad, FM; Neudeck, G; Ngamsri, KC; Reutershan, J; Thiel, M; Vollmer, I, 2013)
"These results indicate that meconium aspiration induces severe inflammation in the lung."1.38The effects of pentoxifylline on lung inflammation in a rat model of meconium aspiration syndrome. ( Atıcı, A; Helvacı, İ; Muşlu, N; Polat, A; Turhan, AH, 2012)
"Pentoxifylline (PTX) has been shown to attenuate neutrophil activation and end-organ injury in shock states such as hemorrhage and sepsis."1.35Pentoxifylline attenuates pulmonary inflammation and neutrophil activation in experimental acute pancreatitis. ( Coimbra, R; de Campos, T; Deree, J; Loomis, WH; Martins, JO; Putnam, JG; Shenvi, E, 2008)
"Pentoxifylline was effective in reducing inflammatory lung injury associated with high tidal volume ventilation."1.35The effect of pentoxifylline on the pulmonary response to high tidal volume ventilation in rats. ( Bancalari, E; Devia, C; Hehre, D; Lessa, A; Suguihara, C; Xianyu, S, 2008)
"Pentoxifylline-treated animals had lower levels of lysozyme (p < ."1.29Effects of pentoxifylline on in vivo leukocyte function and clearance of group B streptococci from preterm rabbit lungs. ( Aeberhard, EE; Gilliam, MB; Mah, MP; Sherman, MP, 1993)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (36.36)18.2507
2000's3 (27.27)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
DiNicolantonio, JJ1
Barroso-Aranda, J1
Konrad, FM1
Neudeck, G1
Vollmer, I1
Ngamsri, KC1
Thiel, M1
Reutershan, J1
Sunil, VR1
Vayas, KN1
Cervelli, JA1
Malaviya, R1
Hall, L1
Massa, CB1
Gow, AJ1
Laskin, JD1
Laskin, DL1
de Campos, T1
Deree, J1
Martins, JO1
Loomis, WH1
Shenvi, E1
Putnam, JG1
Coimbra, R1
Turhan, AH1
Atıcı, A1
Muşlu, N1
Polat, A1
Helvacı, İ1
Lessa, A1
Suguihara, C1
Xianyu, S1
Hehre, D1
Devia, C1
Bancalari, E1
Mah, MP1
Aeberhard, EE1
Gilliam, MB1
Sherman, MP1
Jagielo, PJ1
Watt, JL1
Quinn, TJ1
Knapp, HR1
Schwartz, DA1
Konstan, MW1
Thorne, PS1
McCray, PB1
Howe, TS1
O'Neill, MA1
Goffin, J1
Kreisman, H1
Sandor, V1

Reviews

1 review available for pentoxifylline and Pneumonia

ArticleYear
Treatment of airway inflammation in cystic fibrosis.
    Current opinion in pulmonary medicine, 1996, Volume: 2, Issue:6

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Age Factors; Anti-Inflammatory Agents; Anti-Inf

1996

Trials

1 trial available for pentoxifylline and Pneumonia

ArticleYear
Pentoxifylline does not alter the response to inhaled grain dust.
    Chest, 1997, Volume: 111, Issue:5

    Topics: Administration, Inhalation; Adult; Airway Obstruction; Bronchial Hyperreactivity; Bronchoalveolar La

1997

Other Studies

9 other studies available for pentoxifylline and Pneumonia

ArticleYear
Harnessing adenosine A2A receptors as a strategy for suppressing the lung inflammation and thrombotic complications of COVID-19: Potential of pentoxifylline and dipyridamole.
    Medical hypotheses, 2020, Volume: 143

    Topics: Adenosine A2 Receptor Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Betacoronavirus; C

2020
Protective effects of pentoxifylline in pulmonary inflammation are adenosine receptor A2A dependent.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013, Volume: 27, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cells, Cultured; Humans; Immunohistochemistry;

2013
Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation.
    Experimental and molecular pathology, 2014, Volume: 97, Issue:1

    Topics: Acute Lung Injury; Animals; Chemical Warfare Agents; Cyclooxygenase 2; Heme Oxygenase-1; Irritants;

2014
Pentoxifylline attenuates pulmonary inflammation and neutrophil activation in experimental acute pancreatitis.
    Pancreas, 2008, Volume: 37, Issue:1

    Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents; Chemokine CXCL1; Disease Models, Animal;

2008
The effects of pentoxifylline on lung inflammation in a rat model of meconium aspiration syndrome.
    Experimental lung research, 2012, Volume: 38, Issue:5

    Topics: Animals; Arteries; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Infant, Newborn; Lu

2012
The effect of pentoxifylline on the pulmonary response to high tidal volume ventilation in rats.
    Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:1

    Topics: Animals; Bronchoalveolar Lavage Fluid; Female; Inflammation Mediators; Lung; Pentoxifylline; Peroxid

2008
Effects of pentoxifylline on in vivo leukocyte function and clearance of group B streptococci from preterm rabbit lungs.
    Critical care medicine, 1993, Volume: 21, Issue:5

    Topics: Animals; Animals, Newborn; Bronchoalveolar Lavage Fluid; Colony Count, Microbial; Disease Models, An

1993
Early-onset inflammatory responses in vivo to adenoviral vectors in the presence or absence of lipopolysaccharide-induced inflammation.
    American journal of respiratory cell and molecular biology, 1999, Volume: 20, Issue:6

    Topics: Adenoviridae; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalv

1999
Bleomycin-induced lung toxicity and pentoxifylline.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Jan-15, Volume: 19, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Enzyme I

2001