pentoxifylline has been researched along with Peritonitis in 21 studies
Peritonitis: INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the role of pentoxifylline as an adjuvant to operation and routine antibiotic treatment for perforated peritonitis." | 9.09 | Pentoxifylline in perforated peritonitis: results of a randomised, placebo controlled trial. ( Ojha, AK; Pandey, BL; Pandey, M; Shukla, VK, 2001) |
| "In cirrhotic rats with ascites: (a) pentoxifylline as well as norfloxacin reduced intestinal bacterial overgrowth and bacterial translocation and prevented spontaneous bacterial peritonitis; (b) pentoxifylline, but not norfloxacin, reduced oxidative stress in cecal mucosal." | 7.78 | Effects of pentoxifylline on intestinal bacterial overgrowth, bacterial translocation and spontaneous bacterial peritonitis in cirrhotic rats with ascites. ( Acevedo, J; Brusasco, C; Corradi, F; Fernández, J; Fernández-Varo, G; Gines, P; Mosbah, IB; Navasa, M; Pelosi, P; Ramirez, MJ; Rocco, PR; Seva-Pereira, T; Silva, A; Vila, J, 2012) |
| "The influence and relation between pentoxifylline (PTX) dose and time of administration and mortality rate of animals with experimental peritonitis (EP) were studied." | 7.72 | [The influence of pentoxifylline on the course of experimental peritonitis]. ( Czarnecki, P; Markert, R; Modzelewski, B, 2004) |
| "The aim of this study was to determine the effects of nimesulide and pentoxifylline on the contractile effects of KCl, carbachol and substance P in the longitudinal muscle of rat ileum during peritonitis." | 7.71 | Effects of nimesulide and pentoxifylline on decreased contractile responses in rat ileum with peritonitis. ( Arpacik, M; Karadas, B; Kaya, TT; Koyluoglu, G; Soydan, AS, 2002) |
| " An animal model of peritonitis was used to evaluate the effect of pentoxifylline." | 7.69 | Pentoxifylline improves intracellular electrolytes in sepsis. ( Boston, VE; Refsum, SE; Rowlands, BJ, 1994) |
| "We investigated pentoxifylline (PTF) as a pretreatment of septic syndrome in pigs with fecal peritonitis." | 7.68 | Pretreatment with pentoxifylline improves the hemodynamic and histologic changes and decreases neutrophil adhesiveness in a pig fecal peritonitis model. ( al-Saady, N; Bennett, ED; Boghossian, S; Heath, MF; Hynd, J; Moss, R; Tighe, D, 1990) |
| " Those in the first group were sham operated, and those in the second and third groups underwent peritonitis induction; those in the latter group were treated with pentoxifylline (PTF)." | 7.67 | Pentoxifylline reduces pulmonary leucostasis and improves capillary patency in a rabbit peritonitis model. ( Bennett, ED; Heath, MF; Hynd, J; Moss, R; Tighe, D, 1989) |
| "The objective of this study was to determine the effect of pentoxifylline on the clinical and pathologic course of experimentally induced peritonitis in rats." | 7.67 | Pentoxifylline in the treatment of experimental peritonitis in rats. ( Chalkiadakis, GE; Chalkiadakis, ME; Giamarellou, H; Karayannacos, PE; Kostakis, A; Sgouromali, S; Skalkeas, GD, 1985) |
| "To evaluate the role of pentoxifylline as an adjuvant to operation and routine antibiotic treatment for perforated peritonitis." | 5.09 | Pentoxifylline in perforated peritonitis: results of a randomised, placebo controlled trial. ( Ojha, AK; Pandey, BL; Pandey, M; Shukla, VK, 2001) |
| "In cirrhotic rats with ascites: (a) pentoxifylline as well as norfloxacin reduced intestinal bacterial overgrowth and bacterial translocation and prevented spontaneous bacterial peritonitis; (b) pentoxifylline, but not norfloxacin, reduced oxidative stress in cecal mucosal." | 3.78 | Effects of pentoxifylline on intestinal bacterial overgrowth, bacterial translocation and spontaneous bacterial peritonitis in cirrhotic rats with ascites. ( Acevedo, J; Brusasco, C; Corradi, F; Fernández, J; Fernández-Varo, G; Gines, P; Mosbah, IB; Navasa, M; Pelosi, P; Ramirez, MJ; Rocco, PR; Seva-Pereira, T; Silva, A; Vila, J, 2012) |
| "The influence and relation between pentoxifylline (PTX) dose and time of administration and mortality rate of animals with experimental peritonitis (EP) were studied." | 3.72 | [The influence of pentoxifylline on the course of experimental peritonitis]. ( Czarnecki, P; Markert, R; Modzelewski, B, 2004) |
| "The aim of this study was to determine the effects of nimesulide and pentoxifylline on the contractile effects of KCl, carbachol and substance P in the longitudinal muscle of rat ileum during peritonitis." | 3.71 | Effects of nimesulide and pentoxifylline on decreased contractile responses in rat ileum with peritonitis. ( Arpacik, M; Karadas, B; Kaya, TT; Koyluoglu, G; Soydan, AS, 2002) |
| " The purpose of this study was to evaluate the ability of pentoxifylline to alter gut cytokine production in a rat model of prolonged acute peritonitis, to determine its effect on survival in such animals, and to determine whether alteration of gut cytokine production was associated with survival." | 3.70 | Effect of pentoxifylline on survival and intestinal cytokine messenger RNA transcription in a rat model of ongoing peritoneal sepsis. ( Alexander, JW; Mao, JX; Nelson, JL; Ogle, CK; Vohs, T, 1999) |
| " An animal model of peritonitis was used to evaluate the effect of pentoxifylline." | 3.69 | Pentoxifylline improves intracellular electrolytes in sepsis. ( Boston, VE; Refsum, SE; Rowlands, BJ, 1994) |
| "We investigated pentoxifylline (PTF) as a pretreatment of septic syndrome in pigs with fecal peritonitis." | 3.68 | Pretreatment with pentoxifylline improves the hemodynamic and histologic changes and decreases neutrophil adhesiveness in a pig fecal peritonitis model. ( al-Saady, N; Bennett, ED; Boghossian, S; Heath, MF; Hynd, J; Moss, R; Tighe, D, 1990) |
| " Those in the first group were sham operated, and those in the second and third groups underwent peritonitis induction; those in the latter group were treated with pentoxifylline (PTF)." | 3.67 | Pentoxifylline reduces pulmonary leucostasis and improves capillary patency in a rabbit peritonitis model. ( Bennett, ED; Heath, MF; Hynd, J; Moss, R; Tighe, D, 1989) |
| "The objective of this study was to determine the effect of pentoxifylline on the clinical and pathologic course of experimentally induced peritonitis in rats." | 3.67 | Pentoxifylline in the treatment of experimental peritonitis in rats. ( Chalkiadakis, GE; Chalkiadakis, ME; Giamarellou, H; Karayannacos, PE; Kostakis, A; Sgouromali, S; Skalkeas, GD, 1985) |
| "Valproic acid (VA) is a major antiepileptic drug, used for several therapeutic indications." | 1.39 | Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties. ( Correia, AO; da Graça Naffah-Mazzacorati, M; de Castro Brito, GA; de Oliveira Gonçalves, D; Félix, FH; Leal, LK; Neves, KR; Santos Cerqueira, G; Siqueira, RM; Viana, GS; Ximenes, JC, 2013) |
| "The problem of sepsis and septic shock (SSH) is known to be very actual due to peak-shaped growth of the number of such patients and unsatisfactory results of treatment." | 1.32 | [Septic shock]. ( Bagnenko, SF; Grinev, MV; Gromov, MI; Kulibaba, DM, 2004) |
| "Diffuse peritonitis was elicited by means of cecal ligation and puncture (CLP) in 45 adult Wistar rats." | 1.32 | Pentoxyphilline as a cyclooxygenase (cox-2) inhibitor in experimental sepsis. ( Janiak, A; Modzelewski, B, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 10 (47.62) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ximenes, JC | 1 |
| de Oliveira Gonçalves, D | 1 |
| Siqueira, RM | 1 |
| Neves, KR | 1 |
| Santos Cerqueira, G | 1 |
| Correia, AO | 1 |
| Félix, FH | 1 |
| Leal, LK | 1 |
| de Castro Brito, GA | 1 |
| da Graça Naffah-Mazzacorati, M | 1 |
| Viana, GS | 1 |
| Sireesh, I | 1 |
| Kaman, L | 1 |
| Singh, R | 1 |
| Corradi, F | 1 |
| Brusasco, C | 1 |
| Fernández, J | 1 |
| Vila, J | 1 |
| Ramirez, MJ | 1 |
| Seva-Pereira, T | 1 |
| Fernández-Varo, G | 1 |
| Mosbah, IB | 1 |
| Acevedo, J | 1 |
| Silva, A | 1 |
| Rocco, PR | 1 |
| Pelosi, P | 1 |
| Gines, P | 1 |
| Navasa, M | 1 |
| Grinev, MV | 1 |
| Bagnenko, SF | 1 |
| Kulibaba, DM | 1 |
| Gromov, MI | 1 |
| Modzelewski, B | 2 |
| Janiak, A | 1 |
| Czarnecki, P | 1 |
| Markert, R | 1 |
| Shevkhuzhev, ZA | 1 |
| Khanamatov, MKh | 1 |
| Refsum, SE | 4 |
| McCaigue, M | 2 |
| Campbell, GR | 1 |
| Barclay, GR | 1 |
| Erwin, PJ | 1 |
| Rowlands, BJ | 4 |
| Boston, VE | 4 |
| Halliday, MI | 2 |
| Norwood, W | 1 |
| Campbell, G | 1 |
| Quezado, ZM | 1 |
| Hoffman, WD | 1 |
| Banks, SM | 1 |
| Danner, RL | 1 |
| Eichacker, PQ | 1 |
| Susla, GM | 1 |
| Natanson, C | 1 |
| Fink, MP | 1 |
| Nelson, JL | 1 |
| Alexander, JW | 1 |
| Mao, JX | 1 |
| Vohs, T | 1 |
| Ogle, CK | 1 |
| Karimov, ShI | 1 |
| Babadzhanov, BD | 1 |
| Teshaev, OR | 1 |
| Beketov, GI | 1 |
| Kasymov, UK | 1 |
| Ruzmetov, PIu | 1 |
| Shukla, VK | 1 |
| Ojha, AK | 1 |
| Pandey, M | 1 |
| Pandey, BL | 1 |
| Kaya, TT | 1 |
| Koyluoglu, G | 1 |
| Soydan, AS | 1 |
| Arpacik, M | 1 |
| Karadas, B | 1 |
| Tighe, D | 3 |
| Moss, R | 3 |
| Hynd, J | 2 |
| Boghossian, S | 1 |
| al-Saady, N | 1 |
| Heath, MF | 3 |
| Bennett, ED | 3 |
| Chalkiadakis, GE | 1 |
| Kostakis, A | 1 |
| Karayannacos, PE | 1 |
| Chalkiadakis, ME | 1 |
| Sgouromali, S | 1 |
| Giamarellou, H | 1 |
| Skalkeas, GD | 1 |
2 trials available for pentoxifylline and Peritonitis
| Article | Year |
|---|---|
Pentoxifylline as an adjuvant to surgery and antibiotics in the treatment of perforation peritonitis: a prospective, randomised placebo-controlled study.
Topics: Adjuvants, Pharmaceutic; Adult; Anti-Bacterial Agents; Combined Modality Therapy; Female; Humans; Ma | 2008 |
Pentoxifylline in perforated peritonitis: results of a randomised, placebo controlled trial.
Topics: Adolescent; Adult; Antibiotic Prophylaxis; APACHE; Combined Modality Therapy; Double-Blind Method; F | 2001 |
19 other studies available for pentoxifylline and Peritonitis
| Article | Year |
|---|---|
Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Butyric Acid; Carrageenan; Drug Syne | 2013 |
Effects of pentoxifylline on intestinal bacterial overgrowth, bacterial translocation and spontaneous bacterial peritonitis in cirrhotic rats with ascites.
Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Ascites; Ascitic Fluid; Bacterial Translocatio | 2012 |
[Septic shock].
Topics: Abdominal Injuries; Adjuvants, Immunologic; Anti-Bacterial Agents; Blood Transfusion; Enzyme Inhibit | 2004 |
Pentoxyphilline as a cyclooxygenase (cox-2) inhibitor in experimental sepsis.
Topics: Animals; Antigens, CD; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dis | 2004 |
[The influence of pentoxifylline on the course of experimental peritonitis].
Topics: Animals; Disease Models, Animal; Male; Pentoxifylline; Peritonitis; Phosphodiesterase Inhibitors; Ra | 2004 |
[Endolymphatic drug infusion in the treatment of complicated acute appendicitis].
Topics: Abscess; Acute Disease; Anti-Bacterial Agents; Appendicitis; Aprotinin; Aspirin; Cefotaxime; Ceftazi | 1993 |
Pentoxifylline modulates cytokine responses in a sepsis model.
Topics: Animals; Antibodies; Blood Pressure; Cytokines; Disease Models, Animal; Endotoxins; Female; Interleu | 1994 |
Pentoxifylline improves intracellular electrolytes in sepsis.
Topics: Animals; Chlorides; Electrolytes; Extracellular Space; Hyponatremia; Membrane Potentials; Muscles; P | 1994 |
Pentoxifylline improves resting membrane potential in sepsis.
Topics: Animals; Bacterial Infections; Drug Administration Schedule; Female; Membrane Potentials; Muscles; P | 1993 |
Modulation of TNF alpha and IL-6 in a peritonitis model using pentoxifylline.
Topics: Animals; Blood Pressure; Cecum; Disease Models, Animal; Female; Interleukin-6; Intestinal Perforatio | 1996 |
Increasing doses of pentoxifylline as a continuous infusion in canine septic shock.
Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Body Temperature; Disease Models, Animal; Dogs | 1999 |
Whither pentoxifylline?
Topics: Animals; Bacteremia; Dose-Response Relationship, Drug; Pentoxifylline; Peritonitis; Phosphodiesteras | 1999 |
Effect of pentoxifylline on survival and intestinal cytokine messenger RNA transcription in a rat model of ongoing peritoneal sepsis.
Topics: Animals; Bacteremia; Critical Care; Cytokines; Dietary Proteins; Disease Models, Animal; Dose-Respon | 1999 |
[Role of prolonged intraarterial catheter therapy in general peritonitis].
Topics: Adult; Anti-Bacterial Agents; Aorta, Abdominal; Catheters, Indwelling; Dextrans; Drug Therapy, Combi | 2000 |
Effects of nimesulide and pentoxifylline on decreased contractile responses in rat ileum with peritonitis.
Topics: Animals; Carbachol; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; | 2002 |
Pretreatment with pentoxifylline improves the hemodynamic and histologic changes and decreases neutrophil adhesiveness in a pig fecal peritonitis model.
Topics: Animals; Hemodynamics; Liver; Lung; Models, Biological; Neutrophils; Pentoxifylline; Peritonitis; Sp | 1990 |
Relevance of serum phospholipase A2 assays to the assessment of septic shock.
Topics: Animals; Models, Biological; Pentoxifylline; Peritonitis; Phospholipases; Phospholipases A; Phosphol | 1990 |
Pentoxifylline reduces pulmonary leucostasis and improves capillary patency in a rabbit peritonitis model.
Topics: Animals; Capillaries; Endothelium; Epithelium; Leukocytes; Lung; Microscopy, Electron; Pentoxifyllin | 1989 |
Pentoxifylline in the treatment of experimental peritonitis in rats.
Topics: Abscess; Animals; Female; Male; Pentoxifylline; Peritonitis; Prognosis; Rats; Rats, Inbred Strains; | 1985 |