pentoxifylline has been researched along with Parkinson Disease in 3 studies
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentoxifylline is a synthetic derivative of xantine which stimulates adenosine receptors, inhibit phosphodiesterase and increases cyclic monophosphate adenosine." | 1.31 | [Parkinsonism or Parkinson's disease unmasked by pentoxifylline?]. ( Serrano-Dueñas, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Maclagan, LC | 1 |
| Visanji, NP | 1 |
| Cheng, Y | 1 |
| Tadrous, M | 1 |
| Lacoste, AMB | 1 |
| Kalia, LV | 1 |
| Bronskill, SE | 1 |
| Marras, C | 1 |
| Godwin-Austen, RB | 1 |
| Twomey, JA | 1 |
| Hanks, G | 1 |
| Higgins, J | 1 |
| Serrano-Dueñas, M | 1 |
3 other studies available for pentoxifylline and Parkinson Disease
| Article | Year |
|---|---|
Identifying drugs with disease-modifying potential in Parkinson's disease using artificial intelligence and pharmacoepidemiology.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Artificial Intelligence; Case-Control Studies; Dexame | 2020 |
Oxpentifylline in Parkinson's disease.
Topics: Adult; Aged; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle | 1980 |
[Parkinsonism or Parkinson's disease unmasked by pentoxifylline?].
Topics: Aged; Aged, 80 and over; Female; Humans; Male; Parkinson Disease; Parkinson Disease, Secondary; Park | 2001 |