pentoxifylline has been researched along with Parasitemia in 7 studies
Parasitemia: The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of pentoxifylline (PTX) was tested for its capacity to modulate cytokine responses during therapy of severe Plasmodium falciparum malaria in a placebo-controlled, randomized study in 45 adult patients in Bangkok, Thailand." | 9.08 | Effect of pentoxifylline on cytokine patterns in the therapy of complicated Plasmodium falciparum malaria. ( Graninger, W; Looareesuwan, S; Parschalk, B; Vannapann, S; Wanaratana, V; Wenisch, C; Wernsdorfer, W; Wilairatana, P, 1998) |
| "Pentoxifylline (PTX) affects many processes that may contribute to the pathogenesis of severe malaria and it has been shown to reduce the duration of coma in children with cerebral malaria." | 7.76 | Pentoxifylline as an adjunct therapy in children with cerebral malaria. ( Kivaya, E; Köhler, C; Kokwaro, G; Kremsner, PG; Lell, B; Mithwani, S; Newton, CR; Olola, CH; Taylor, TE; Wamola, B; Wypij, D, 2010) |
| "The effect of pentoxifylline (PTX) was tested for its capacity to modulate cytokine responses during therapy of severe Plasmodium falciparum malaria in a placebo-controlled, randomized study in 45 adult patients in Bangkok, Thailand." | 5.08 | Effect of pentoxifylline on cytokine patterns in the therapy of complicated Plasmodium falciparum malaria. ( Graninger, W; Looareesuwan, S; Parschalk, B; Vannapann, S; Wanaratana, V; Wenisch, C; Wernsdorfer, W; Wilairatana, P, 1998) |
| "Pentoxifylline (PTX) affects many processes that may contribute to the pathogenesis of severe malaria and it has been shown to reduce the duration of coma in children with cerebral malaria." | 3.76 | Pentoxifylline as an adjunct therapy in children with cerebral malaria. ( Kivaya, E; Köhler, C; Kokwaro, G; Kremsner, PG; Lell, B; Mithwani, S; Newton, CR; Olola, CH; Taylor, TE; Wamola, B; Wypij, D, 2010) |
| " In the present study, pentoxifylline (PTX), an inhibitor of TNF-alpha was investigated on its action upon splenic necrosis, parasitemia and host survival." | 3.74 | Importance of TNF-alpha in the course of acute infection with Trypanosoma cruzi: influence of its inhibition by pentoxifylline treatment. ( Andrade, SG; Magalhães, Ldos A; Pessina, DH, 2008) |
| "Pentoxifylline (POF) may suppress overproduction of tumor necrosis factor alpha (TNF alpha), which is thought to contribute to complications of human falciparum malaria." | 2.68 | Supportive pentoxifylline in falciparum malaria: no effect on tumor necrosis factor alpha levels or clinical outcome: a prospective, randomized, placebo-controlled study. ( Chiwakata, CB; Dietrich, M; Egbring, R; Gaus, W; Hassemer, M; Hemmer, CJ; Hogel, J; Hort, G; Kern, P; Nawroth, PP; Seitz, R, 1997) |
| "Cerebral malaria is associated with the circulating levels of tumour necrosis factor alpha (TNF-α) and transforming growth factor β (TGF-β), but association between these two cytokines and implications in splenocyte apoptosis remain largely obscured." | 1.39 | Splenocyte apoptosis in Plasmodium berghei ANKA infection: possible role of TNF-α and TGF-β. ( Bhattacharyya, A; Keswani, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lell, B | 1 |
| Köhler, C | 1 |
| Wamola, B | 1 |
| Olola, CH | 1 |
| Kivaya, E | 1 |
| Kokwaro, G | 1 |
| Wypij, D | 1 |
| Mithwani, S | 1 |
| Taylor, TE | 1 |
| Kremsner, PG | 1 |
| Newton, CR | 1 |
| Keswani, T | 1 |
| Bhattacharyya, A | 1 |
| Roggero, E | 1 |
| Piazzon, I | 1 |
| Nepomnaschy, I | 1 |
| Perez, A | 1 |
| Velikovsky, A | 1 |
| Revelli, S | 1 |
| Bottasso, O | 1 |
| Andrade, SG | 1 |
| Magalhães, Ldos A | 1 |
| Pessina, DH | 1 |
| Hemmer, CJ | 1 |
| Hort, G | 1 |
| Chiwakata, CB | 1 |
| Seitz, R | 1 |
| Egbring, R | 1 |
| Gaus, W | 1 |
| Hogel, J | 1 |
| Hassemer, M | 1 |
| Nawroth, PP | 1 |
| Kern, P | 1 |
| Dietrich, M | 1 |
| Wenisch, C | 1 |
| Looareesuwan, S | 1 |
| Wilairatana, P | 1 |
| Parschalk, B | 1 |
| Vannapann, S | 1 |
| Wanaratana, V | 1 |
| Wernsdorfer, W | 1 |
| Graninger, W | 1 |
| Voza, T | 1 |
| Gautret, P | 1 |
| Renia, L | 1 |
| Gantier, JC | 1 |
| Lombard, MN | 1 |
| Chabaud, AG | 1 |
| Landau, I | 1 |
2 trials available for pentoxifylline and Parasitemia
| Article | Year |
|---|---|
Supportive pentoxifylline in falciparum malaria: no effect on tumor necrosis factor alpha levels or clinical outcome: a prospective, randomized, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Antimalarials; Biopterins; Drug Therapy, Combi | 1997 |
Effect of pentoxifylline on cytokine patterns in the therapy of complicated Plasmodium falciparum malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Cytokines; Drug Therapy, Combination; Fever; Humans; Interl | 1998 |
5 other studies available for pentoxifylline and Parasitemia
| Article | Year |
|---|---|
Pentoxifylline as an adjunct therapy in children with cerebral malaria.
Topics: Antimalarials; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Infusions | 2010 |
Splenocyte apoptosis in Plasmodium berghei ANKA infection: possible role of TNF-α and TGF-β.
Topics: Animals; Apoptosis; Benzamides; Cell Survival; Dioxoles; Fas Ligand Protein; Flow Cytometry; Gene Ex | 2013 |
Thymocyte depletion during acute Trypanosoma cruzi infection in C57BL/6 mice is partly reverted by lipopolysaccharide pretreatment.
Topics: Animals; Antibodies, Monoclonal; Chagas Disease; Flow Cytometry; Heart; Interleukin-10; Interleukin- | 2004 |
Importance of TNF-alpha in the course of acute infection with Trypanosoma cruzi: influence of its inhibition by pentoxifylline treatment.
Topics: Acute Disease; Animals; Chagas Disease; Immunohistochemistry; Mice; Mice, Inbred C3H; Necrosis; Para | 2008 |
Variation in murid Plasmodium desequestration and its modulation by stress and pentoxifylline.
Topics: Animals; Disease Models, Animal; Hematologic Agents; Malaria; Mice; Parasitemia; Pentoxifylline; Pla | 2002 |