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pentoxifylline and Paraparesis, Tropical Spastic

pentoxifylline has been researched along with Paraparesis, Tropical Spastic in 5 studies

Paraparesis, Tropical Spastic: A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by HUMAN T-CELL LEUKEMIA VIRUS I. Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakagawa, M1
Nakahara, K1
Maruyama, Y1
Kawabata, M1
Higuchi, I1
Kubota, H1
Izumo, S1
Arimura, K1
Osame, M1
Tsujino, A2
Nakamura, T3
Nishiura, Y2
Shirabe, S3
Furuya, T3
Goto, H2
Kawakami, A1
Eguchi, K2
Nagataki, S2
Hatae, T1
Hara, H1
Kobayashi, T1
Watanabe, T1
Suenaga, A1
Nakane, S2
Yoshimura, T2
Fujimoto, T1
Kambara, C1
Hamasaki, S1

Trials

2 trials available for pentoxifylline and Paraparesis, Tropical Spastic

ArticleYear
Therapeutic trials in 200 patients with HTLV-I-associated myelopathy/ tropical spastic paraparesis.
    Journal of neurovirology, 1996, Volume: 2, Issue:5

    Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory A

1996
Successful application of pentoxifylline in the treatment of HTLV-I associated myelopathy.
    Journal of the neurological sciences, 1997, Oct-03, Volume: 151, Issue:1

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Paraparesis, Tropical Spastic; Pentoxifylline; Prosp

1997

Other Studies

3 other studies available for pentoxifylline and Paraparesis, Tropical Spastic

ArticleYear
Pentoxifylline down-regulates adhesion molecule expression and inflammatory cytokine production in cultured peripheral blood mononuclear cells from patients with HTLV-I-associated myelopathy.
    Journal of neuroimmunology, 1997, Volume: 73, Issue:1-2

    Topics: Adult; Aged; CD4 Antigens; CD8 Antigens; Cell Adhesion Molecules; Cell Division; Cells, Cultured; Cy

1997
The effect of rolipram on the production of cytokines in HTLV-I infected cell lines and peripheral blood mononuclear cells of patients with HTLV-I-associated myelopathy (HAM).
    Journal of the neurological sciences, 1997, May-01, Volume: 148, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Gene Expression; HTLV-I Infections; Humans

1997
Relationship between the clinical efficacy of pentoxifylline treatment and elevation of serum T helper type 2 cytokine levels in patients with human T-lymphotropic virus type I-associated myelopathy.
    Internal medicine (Tokyo, Japan), 1999, Volume: 38, Issue:9

    Topics: Administration, Oral; Adult; Aged; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; Humans; In

1999