pentoxifylline has been researched along with Neuralgia in 12 studies
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The patients received PTX at the initiating dosage until complete clinical cure." | 6.71 | [Pentoxifylline in the treatment of erythema nodosum leprosum: results of an open study]. ( Achirafi, A; de Carsalade, GY; Flageul, B, 2003) |
| "Pentoxifylline (PTX) has strong antyinflamatory effects, decreases TNF-alpha and other proinflammatory cytokines production." | 5.38 | Pentoxifylline modifies central and peripheral vagal mechanism in acute and chronic pain models. ( Dobrogowski, J; Nowak, Ł; Thor, PJ; Wordliczek, J; Zurowski, D, 2012) |
| "After the rats developed neuropathic pain behavior, a single intraperitoneal injection and continuous infusion of pentoxifylline ameliorated paclitaxel-induced mechanical allodynia." | 3.83 | Pentoxifylline Ameliorates Mechanical Hyperalgesia in a Rat Model of Chemotherapy-Induced Neuropathic Pain. ( Abdi, S; Hwang, SH; Kim, HK; Kim, SH; Lee, SO, 2016) |
| "First-line pharmacotherapy for neuropathic pain entails the use of systemic antidepressants and anticonvulsants." | 3.01 | The effect of a topical combination of clonidine and pentoxifylline on post-traumatic neuropathic pain patients: study protocol for a randomized, double-blind placebo-controlled trial. ( Coderre, TJ; Fulas, OA; Laferrière, A; Shir, Y; Ware, DMA, 2021) |
| "Type 2 lepra reaction (T2R) is a difficult-to-manage condition in leprosy, and an effective and safe steroid-sparing agent is needed for its management." | 2.80 | Effectiveness and safety of clofazimine and pentoxifylline in type 2 lepra reaction: a double-blind, randomized, controlled study. ( Bandyopadhyay, D; Das, NK; Roy, K; Sil, A, 2015) |
| " The patients received PTX at the initiating dosage until complete clinical cure." | 2.71 | [Pentoxifylline in the treatment of erythema nodosum leprosum: results of an open study]. ( Achirafi, A; de Carsalade, GY; Flageul, B, 2003) |
| "Pentoxifylline (PTX) has strong antyinflamatory effects, decreases TNF-alpha and other proinflammatory cytokines production." | 1.38 | Pentoxifylline modifies central and peripheral vagal mechanism in acute and chronic pain models. ( Dobrogowski, J; Nowak, Ł; Thor, PJ; Wordliczek, J; Zurowski, D, 2012) |
| "In patients with HIV/AIDS, neuropathic pain is a common neurological complication." | 1.37 | TNFα is involved in neuropathic pain induced by nucleoside reverse transcriptase inhibitor in rats. ( Fink, DJ; Hao, S; Liu, S; Mata, M; Ouyang, H; Zheng, X, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Fulas, OA | 2 |
| Laferrière, A | 2 |
| Coderre, TJ | 2 |
| Ware, DMA | 1 |
| Shir, Y | 1 |
| Nowak, Ł | 1 |
| Zurowski, D | 1 |
| Dobrogowski, J | 1 |
| Wordliczek, J | 1 |
| Thor, PJ | 1 |
| Roy, K | 1 |
| Sil, A | 1 |
| Das, NK | 1 |
| Bandyopadhyay, D | 1 |
| Kim, HK | 1 |
| Hwang, SH | 1 |
| Lee, SO | 1 |
| Kim, SH | 1 |
| Abdi, S | 1 |
| Mika, J | 2 |
| Osikowicz, M | 2 |
| Rojewska, E | 1 |
| Korostynski, M | 1 |
| Wawrzczak-Bargiela, A | 1 |
| Przewlocki, R | 1 |
| Przewlocka, B | 2 |
| Zheng, X | 1 |
| Ouyang, H | 1 |
| Liu, S | 1 |
| Mata, M | 1 |
| Fink, DJ | 1 |
| Hao, S | 1 |
| de Carsalade, GY | 1 |
| Achirafi, A | 1 |
| Flageul, B | 1 |
| Mulleman, D | 1 |
| Mammou, S | 1 |
| Griffoul, I | 1 |
| Watier, H | 1 |
| Goupille, P | 1 |
| Liu, J | 1 |
| Feng, X | 1 |
| Yu, M | 1 |
| Xie, W | 1 |
| Zhao, X | 1 |
| Li, W | 1 |
| Guan, R | 1 |
| Xu, J | 1 |
| Makuch, W | 1 |
| Wernicke, JF | 1 |
| Wang, F | 1 |
| Pritchett, YL | 1 |
| Smith, TR | 1 |
| Raskin, J | 1 |
| D'Souza, DN | 1 |
| Iyengar, S | 1 |
| Chappell, AS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Topical Treatment With Clonidine + Pentoxifylline in Patients With Neuropathic Pain[NCT03342950] | Phase 2 | 4 participants (Actual) | Interventional | 2019-02-19 | Terminated (stopped due to Low recruitment due to the COVID-19 pandemic) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pentoxifylline and Neuralgia
| Article | Year |
|---|---|
Pathophysiology of disk-related low back pain and sciatica. II. Evidence supporting treatment with TNF-alpha antagonists.
Topics: Animals; Antibodies, Monoclonal; Doxycycline; Humans; Infliximab; Low Back Pain; Neuralgia; Pentoxif | 2006 |
4 trials available for pentoxifylline and Neuralgia
| Article | Year |
|---|---|
The effect of a topical combination of clonidine and pentoxifylline on post-traumatic neuropathic pain patients: study protocol for a randomized, double-blind placebo-controlled trial.
Topics: Analgesics; Clonidine; Double-Blind Method; Humans; Neuralgia; Pain Measurement; Pentoxifylline; Ran | 2021 |
Effectiveness and safety of clofazimine and pentoxifylline in type 2 lepra reaction: a double-blind, randomized, controlled study.
Topics: Adult; Arthritis, Reactive; Clofazimine; Double-Blind Method; Female; Humans; Inflammation; Leprosta | 2015 |
[Pentoxifylline in the treatment of erythema nodosum leprosum: results of an open study].
Topics: Adolescent; Adult; Erythema Nodosum; Female; Follow-Up Studies; Glucocorticoids; Humans; Immunosuppr | 2003 |
An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain.
Topics: Acetaminophen; Amitriptyline; Analgesics; Carbamazepine; Diabetes Complications; Diabetic Neuropathi | 2007 |
7 other studies available for pentoxifylline and Neuralgia
| Article | Year |
|---|---|
Novel Co-crystal of Pentoxifylline and Protocatechuic Acid Relieves Allodynia in Rat Models of Peripheral Neuropathic Pain and CRPS by Alleviating Local Tissue Hypoxia.
Topics: Animals; Complex Regional Pain Syndromes; Disease Models, Animal; Hydroxybenzoates; Hyperalgesia; Hy | 2021 |
Pentoxifylline modifies central and peripheral vagal mechanism in acute and chronic pain models.
Topics: Acetic Acid; Acute Pain; Animals; Anti-Inflammatory Agents; Chronic Pain; Cytokines; Hyperalgesia; I | 2012 |
Pentoxifylline Ameliorates Mechanical Hyperalgesia in a Rat Model of Chemotherapy-Induced Neuropathic Pain.
Topics: Analgesics; Animals; Antineoplastic Agents; Cytokines; Disease Models, Animal; Ganglia, Spinal; Hype | 2016 |
Differential activation of spinal microglial and astroglial cells in a mouse model of peripheral neuropathic pain.
Topics: Analgesics; Animals; Astrocytes; Biomarkers; Citrates; Complement C1q; Disease Models, Animal; Glial | 2009 |
TNFα is involved in neuropathic pain induced by nucleoside reverse transcriptase inhibitor in rats.
Topics: Analgesics; Animals; Antigens, Nuclear; Blotting, Western; Glial Fibrillary Acidic Protein; Immunohi | 2011 |
Pentoxifylline attenuates the development of hyperalgesia in a rat model of neuropathic pain.
Topics: Animals; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Hot Temperature; Hyper | 2007 |
Minocycline and pentoxifylline attenuate allodynia and hyperalgesia and potentiate the effects of morphine in rat and mouse models of neuropathic pain.
Topics: Animals; Disease Models, Animal; Drug Synergism; Hyperalgesia; Male; Mice; Minocycline; Morphine; Ne | 2007 |