pentoxifylline has been researched along with Necrosis in 46 studies
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy of pentoxifylline--a haemorrheologic agent along with aspirin--an analgesic agent was evaluated in the amelioration of the tissue damage due to experimentally induced frostbite in 5 groups (20 each) of rats with body weights ranging between 175 and 200 g." | 7.70 | Efficacy of pentoxifylline with aspirin in the treatment of frostbite in rats. ( Chauhan, SK; Purkayastha, SS; Roy, A; Selvamurthy, W; Verma, SS, 1998) |
| "The effect of pretreatment with pentoxifylline on normothermic liver ischemia was studied in rats." | 7.69 | [Liver damage due to normothermic ischemia and reperfusion in the rat. The effects of pentoxifylline pretreatment]. ( Castillo Olivares Ramos, JL; Martínez Onturbe, P; Navidad Novalvos, R; Ratia Giménez, T; Santamaría Solís, LV, 1995) |
| "The administration of pentoxifylline at 25 mg/kg before reperfusion of ischemic skeletal muscle decreased significantly the extent of muscle necrosis and PAF levels in the venous effluents at all times of reperfusion (significantly at 10 minutes)." | 7.69 | Effect of pentoxifylline on tissue injury and platelet-activating factor production during ischemia-reperfusion injury. ( Adams, JG; Dhar, A; Shukla, SD; Silver, D, 1995) |
| "Vascular congestion and liver swelling have long been recognized as features of the hepatotoxic effects of acetaminophen (AAP) in mice and rats and have been proposed as contributing factors to the eventual extent of necrosis produced." | 7.68 | Investigation of possible mechanisms of hepatic swelling and necrosis caused by acetaminophen in mice. ( Benzick, AE; Hansen, TN; Montgomery, CA; Smith, CV; Welty, SE, 1993) |
| "Between September 1988 and August 1989, 12 patients with 15 sites of late radiation necrosis of the soft tissues were treated with pentoxifylline, a hemorrheologic agent that has been used to treat a variety of vasculo-occlusive disorders." | 7.68 | Preliminary results of a pilot study of pentoxifylline in the treatment of late radiation soft tissue necrosis. ( Anderson, B; Dion, MW; Doornbos, JF; Hussey, DH; Vigliotti, AP; Wen, BC, 1990) |
| "5 times) were given pentoxyfylline at a dosage of 400 mg t." | 6.73 | Beneficial effects of pentoxifylline on hepatic steatosis, fibrosis and necroinflammation in patients with non-alcoholic steatohepatitis. ( Malhotra, V; Sakhuja, P; Sarin, SK; Satapathy, SK; Sharma, BC, 2007) |
| "Pentoxifylline (PTX) is a derivative of methylxanthine and is used in peripheral vascular and cerebrovascular diseases for its effect on the regulation of blood circulation." | 5.38 | Effect of pentoxifylline on histopathological changes in steroid-induced osteonecrosis of femoral head: experimental study in chicken. ( Aktas, M; Erken, HY; Ofluoglu, O; Topal, C; Yildiz, M, 2012) |
| "Rabbits sustained spinal cord ischemia following 45 minutes cross-clamping of the infrarenal aorta." | 5.35 | Functional protection of pentoxifylline against spinal cord ischemia/reperfusion injury in rabbits: necrosis and apoptosis effects. ( Bi, Q; Qiu, BS; Xia, B; Zhang, SJ; Zhao, C; Zhu, DJ, 2008) |
| "Pentoxifylline was effective reducing the necrosis in the caudal unipedicle TRAM flap in the rat as well as increasing the number of capillaries in an ischemic zone (zone IV)." | 3.80 | Histological modification in TRAM flap in rats treated with pentoxifylline. ( Brasolin, AG; Feitosa, RG; Ferreira, LM; Gomes, HF; Lucca, AF; Simões e Silva Enokihara, MM, 2014) |
| "The areas of necrosis observed in the degloved flaps of the rats' hind limbs were smaller in the pentoxifylline and allopurinol groups." | 3.79 | Experimental model of degloving injury in rats: effect of allopurinol and pentoxifylline in improving viability of avulsed flaps. ( Ferreira, MC; Milcheski, DA; Nakamoto, HA; Nóbrega, L; Tuma, P, 2013) |
| " In the present study, pentoxifylline (PTX), an inhibitor of TNF-alpha was investigated on its action upon splenic necrosis, parasitemia and host survival." | 3.74 | Importance of TNF-alpha in the course of acute infection with Trypanosoma cruzi: influence of its inhibition by pentoxifylline treatment. ( Andrade, SG; Magalhães, Ldos A; Pessina, DH, 2008) |
| "The efficacy of pentoxifylline--a haemorrheologic agent along with aspirin--an analgesic agent was evaluated in the amelioration of the tissue damage due to experimentally induced frostbite in 5 groups (20 each) of rats with body weights ranging between 175 and 200 g." | 3.70 | Efficacy of pentoxifylline with aspirin in the treatment of frostbite in rats. ( Chauhan, SK; Purkayastha, SS; Roy, A; Selvamurthy, W; Verma, SS, 1998) |
| "The effect of pretreatment with pentoxifylline on normothermic liver ischemia was studied in rats." | 3.69 | [Liver damage due to normothermic ischemia and reperfusion in the rat. The effects of pentoxifylline pretreatment]. ( Castillo Olivares Ramos, JL; Martínez Onturbe, P; Navidad Novalvos, R; Ratia Giménez, T; Santamaría Solís, LV, 1995) |
| "The administration of pentoxifylline at 25 mg/kg before reperfusion of ischemic skeletal muscle decreased significantly the extent of muscle necrosis and PAF levels in the venous effluents at all times of reperfusion (significantly at 10 minutes)." | 3.69 | Effect of pentoxifylline on tissue injury and platelet-activating factor production during ischemia-reperfusion injury. ( Adams, JG; Dhar, A; Shukla, SD; Silver, D, 1995) |
| "In this study, to clarify the role of activated macrophages in the augmentation of endotoxin hepatoxicity, rats were pretreated with zymosan, an activator of macrophages, before the induction of endotoxin hepatotoxicity, and some were given pentoxifylline, an inhibitor of tumour necrosis factor production." | 3.69 | Role of activated macrophages in augmentation of endotoxin hepatotoxicity. ( Asaka, S; Nakata, K; Shibayama, Y, 1994) |
| "Vascular congestion and liver swelling have long been recognized as features of the hepatotoxic effects of acetaminophen (AAP) in mice and rats and have been proposed as contributing factors to the eventual extent of necrosis produced." | 3.68 | Investigation of possible mechanisms of hepatic swelling and necrosis caused by acetaminophen in mice. ( Benzick, AE; Hansen, TN; Montgomery, CA; Smith, CV; Welty, SE, 1993) |
| "Between September 1988 and August 1989, 12 patients with 15 sites of late radiation necrosis of the soft tissues were treated with pentoxifylline, a hemorrheologic agent that has been used to treat a variety of vasculo-occlusive disorders." | 3.68 | Preliminary results of a pilot study of pentoxifylline in the treatment of late radiation soft tissue necrosis. ( Anderson, B; Dion, MW; Doornbos, JF; Hussey, DH; Vigliotti, AP; Wen, BC, 1990) |
| "5 times) were given pentoxyfylline at a dosage of 400 mg t." | 2.73 | Beneficial effects of pentoxifylline on hepatic steatosis, fibrosis and necroinflammation in patients with non-alcoholic steatohepatitis. ( Malhotra, V; Sakhuja, P; Sarin, SK; Satapathy, SK; Sharma, BC, 2007) |
| "Severe alcoholic hepatitis (SAH) is defined by modified Maddrey discriminant function ≥32 or Model for End-Stage Liver Disease (MELD) >21 and/or hepatic encephalopathy." | 2.55 | New paradigms in management of alcoholic hepatitis: a review. ( Goyal, O; Kishore, H; Sidhu, S; Sidhu, SS, 2017) |
| "In the future, these treatments of fibrosis and necrosis should include targeted drugs (such as growth factors) to take organ specificities into account." | 2.44 | Current management for late normal tissue injury: radiation-induced fibrosis and necrosis. ( Delanian, S; Lefaix, JL, 2007) |
| "Pentoxifylline (PTX) is a derivative of methylxanthine and is used in peripheral vascular and cerebrovascular diseases for its effect on the regulation of blood circulation." | 1.38 | Effect of pentoxifylline on histopathological changes in steroid-induced osteonecrosis of femoral head: experimental study in chicken. ( Aktas, M; Erken, HY; Ofluoglu, O; Topal, C; Yildiz, M, 2012) |
| "Ischemia-reperfusion injury is believed to be a major cause of transferred skin flap failure." | 1.36 | Effects of pentoxyfilline and heparin on reperfusion injury island skin flaps in rats exposed to tobacco. ( Cherri, J; Freitas, FA; Marchesan, WG; Piccinato, CE, 2010) |
| "Rabbits sustained spinal cord ischemia following 45 minutes cross-clamping of the infrarenal aorta." | 1.35 | Functional protection of pentoxifylline against spinal cord ischemia/reperfusion injury in rabbits: necrosis and apoptosis effects. ( Bi, Q; Qiu, BS; Xia, B; Zhang, SJ; Zhao, C; Zhu, DJ, 2008) |
| "Glycerol treated rats exhibited collecting duct and medullary ascending limb dilation and casts, with focal tubular damage, confined mainly to the superficial cortex." | 1.31 | Nephroprotective effects of pentoxifylline in experimental myoglobinuric acute renal failure. ( Avramovic, V; Djordjevic, V; Mitic-Zlatkovic, M; Savic, V; Stefanovic, V; Vlahovic, P, 2002) |
| "Pentoxifylline (PTX) pretreatment of recipients was shown to protect against liver graft failure from ischemia-reperfusion injury after orthotopic rat liver transplantation." | 1.31 | Beneficial effects of pentoxifylline pretreatment in non-heart-beating donors in rats. ( Astarcioğlu, H; Astarcioğlu, I; Coker, A; Karademir, S; Menekay, S; Ozer, E; Unek, T, 2000) |
| "Pentoxifylline is a methylxanthine derivative that produces dose-related hemorrheologic effects, lower blood viscosity, improved erythrocyte flexibility, and increased tissue oxygen levels." | 1.30 | Pentoxifylline in the treatment of radiation-related soft tissue injury: preliminary observations. ( Futran, ND; Gwede, C; Trotti, A, 1997) |
| "Flap necrosis is still a significant complication in all types of flap surgery." | 1.30 | Effect of parenteral pentoxifylline and topical nitroglycerin on skin flap survival. ( Akbaş, H; Karacaoğlan, N, 1999) |
| "Pentoxifylline has been shown to improve the deformability of red blood cells by increasing their intracellular adenosine triphosphate content and, therefore, improving their flow properties." | 1.28 | The effects of pentoxifylline on random skin flap survival. ( Maves, MD; Yessenow, RS, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.17) | 18.7374 |
| 1990's | 15 (32.61) | 18.2507 |
| 2000's | 16 (34.78) | 29.6817 |
| 2010's | 11 (23.91) | 24.3611 |
| 2020's | 3 (6.52) | 2.80 |
| Authors | Studies |
|---|---|
| Vaios, EJ | 1 |
| Batich, KA | 1 |
| Buckley, AF | 1 |
| Dunn-Pirio, A | 1 |
| Patel, MP | 1 |
| Kirkpatrick, JP | 1 |
| Goudar, R | 1 |
| Peters, KB | 1 |
| Pedretti, SLDC | 1 |
| Rena, CL | 1 |
| Orellano, LAA | 1 |
| Lazari, MG | 1 |
| Campos, PP | 1 |
| Nunes, TA | 1 |
| Gholami, A | 1 |
| Ataei, S | 1 |
| Ahmadimoghaddam, D | 1 |
| Omidifar, N | 1 |
| Nili-Ahmadabadi, A | 1 |
| Senel, S | 1 |
| Zorlu, P | 1 |
| Dogan, B | 1 |
| Acar, M | 1 |
| Chen, SS | 1 |
| Block, BS | 1 |
| Chan, PJ | 1 |
| Lucca, AF | 1 |
| Brasolin, AG | 1 |
| Feitosa, RG | 1 |
| Simões e Silva Enokihara, MM | 1 |
| Gomes, HF | 1 |
| Ferreira, LM | 1 |
| Migliorini, F | 1 |
| Bianconi, F | 1 |
| Bizzotto, L | 1 |
| Porcaro, AB | 1 |
| Artibani, W | 1 |
| António, NN | 1 |
| Monte Alto Costa, A | 1 |
| Marques, RG | 1 |
| Sidhu, SS | 1 |
| Goyal, O | 1 |
| Kishore, H | 1 |
| Sidhu, S | 1 |
| Zhu, DJ | 1 |
| Xia, B | 1 |
| Bi, Q | 1 |
| Zhang, SJ | 1 |
| Qiu, BS | 1 |
| Zhao, C | 1 |
| Araujo, Ap | 1 |
| Araujo, M | 1 |
| Swoboda, KJ | 1 |
| Kiken, DA | 1 |
| Goldman, MP | 1 |
| Stojiljković, N | 1 |
| Veljković, S | 1 |
| Mihailović, D | 1 |
| Stoiljković, M | 1 |
| Ranković, G | 1 |
| Jovanović, I | 1 |
| Randjelović, P | 1 |
| Freitas, FA | 1 |
| Piccinato, CE | 1 |
| Cherri, J | 1 |
| Marchesan, WG | 1 |
| Jenkins, J | 1 |
| Babu, K | 1 |
| Hsu-Hung, E | 1 |
| Robinson-Bostom, L | 1 |
| Kroumpouzos, G | 1 |
| Elemen, L | 1 |
| Topçu, K | 1 |
| Gürcan, Nİ | 1 |
| Akay, A | 1 |
| Milcheski, DA | 1 |
| Nakamoto, HA | 1 |
| Tuma, P | 1 |
| Nóbrega, L | 1 |
| Ferreira, MC | 1 |
| Erken, HY | 1 |
| Ofluoglu, O | 1 |
| Aktas, M | 1 |
| Topal, C | 1 |
| Yildiz, M | 1 |
| Savic, V | 1 |
| Vlahovic, P | 1 |
| Djordjevic, V | 1 |
| Mitic-Zlatkovic, M | 1 |
| Avramovic, V | 1 |
| Stefanovic, V | 1 |
| Chaves, F | 1 |
| Teixeira, CF | 1 |
| Gutiérrez, JM | 1 |
| Hödl, S | 1 |
| Gorelasvili, A | 1 |
| Antelava, N | 1 |
| Noyan, T | 1 |
| Kömüroğlu, U | 1 |
| Bayram, I | 1 |
| Sekeroğlu, MR | 1 |
| Oztuna, V | 1 |
| Eskandari, MM | 1 |
| Unal, S | 1 |
| Colak, M | 1 |
| Karabacak, T | 1 |
| Delanian, S | 1 |
| Lefaix, JL | 1 |
| Chitturi, S | 1 |
| Farrell, GC | 1 |
| Satapathy, SK | 1 |
| Sakhuja, P | 1 |
| Malhotra, V | 1 |
| Sharma, BC | 1 |
| Sarin, SK | 1 |
| Andrade, SG | 1 |
| Magalhães, Ldos A | 1 |
| Pessina, DH | 1 |
| Ratia Giménez, T | 1 |
| Navidad Novalvos, R | 1 |
| Martínez Onturbe, P | 1 |
| Santamaría Solís, LV | 1 |
| Castillo Olivares Ramos, JL | 1 |
| Adams, JG | 1 |
| Dhar, A | 1 |
| Shukla, SD | 1 |
| Silver, D | 1 |
| Skjeldal, S | 1 |
| Hvaal, K | 1 |
| Nordsletten, L | 1 |
| Aasen, AO | 1 |
| Reikerås, O | 1 |
| Torvik, A | 1 |
| Shibayama, Y | 1 |
| Asaka, S | 1 |
| Nakata, K | 1 |
| Welty, SE | 1 |
| Smith, CV | 1 |
| Benzick, AE | 1 |
| Montgomery, CA | 1 |
| Hansen, TN | 1 |
| Pratt, MF | 1 |
| Futran, ND | 1 |
| Trotti, A | 1 |
| Gwede, C | 1 |
| Aker, JS | 1 |
| Mancoll, J | 1 |
| Lewis, B | 1 |
| Colen, LB | 1 |
| Bekerecioğlu, M | 1 |
| Kutluhan, A | 1 |
| Demirtaş, I | 1 |
| Karaayvaz, M | 1 |
| Shor, NA | 1 |
| Helunenko, AM | 1 |
| Petrunia, AM | 1 |
| Zelenyĭ, II | 1 |
| Purkayastha, SS | 1 |
| Roy, A | 1 |
| Chauhan, SK | 1 |
| Verma, SS | 1 |
| Selvamurthy, W | 1 |
| Karacaoğlan, N | 1 |
| Akbaş, H | 1 |
| Astarcioğlu, H | 1 |
| Karademir, S | 1 |
| Unek, T | 1 |
| Ozer, E | 1 |
| Menekay, S | 1 |
| Coker, A | 1 |
| Astarcioğlu, I | 1 |
| Souza, CS | 1 |
| Roselino, AM | 1 |
| Figueiredo, F | 1 |
| Foss, NT | 1 |
| Galla, TJ | 1 |
| Sätzler, RK | 1 |
| Barker, JH | 1 |
| Messmer, K | 1 |
| Zheng, JW | 1 |
| Dion, MW | 1 |
| Hussey, DH | 1 |
| Doornbos, JF | 1 |
| Vigliotti, AP | 1 |
| Wen, BC | 1 |
| Anderson, B | 1 |
| Yessenow, RS | 1 |
| Maves, MD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Medical Benefit of a Spa Therapy on the Evolutionary Genius of Late Sequelae Fibrosis After Postoperative Radiotherapy for Breast Cancer in Remission[NCT05874492] | 110 participants (Anticipated) | Interventional | 2023-09-30 | Not yet recruiting | |||
| Postoperative or Salvage Radiotherapy for Node Negative Prostate Cancer Following Radical Prostatectomy[NCT00969111] | 70 participants (Anticipated) | Interventional | 2009-08-31 | Recruiting | |||
| An Expanded Phase II Study of Hypofractionated Dose Intense Image Guided Proton Radiation Therapy for Low and Intermediate Risk Adenocarcinoma of the Prostate[NCT01368055] | 361 participants (Actual) | Interventional | 2011-09-30 | Active, not recruiting | |||
| Development of Radiation Fibrosis in Patients Treated With Pentoxyphylline and Vitamin E: a Prospective Randomized Study[NCT00583700] | Phase 2 | 54 participants (Actual) | Interventional | 2003-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
A primary outcome of interest is the composite Subjective, Objective, Management, and Analytic (SOMA) score at 18-month follow-up visit. Maximum score is 45, with a score of 0 being ideal and representing no treatment-related side effects at the study visit. (NCT00583700)
Timeframe: 18 month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Control Arm | 1.59 |
| Intervention: Pentoxifylline & Vitamin E | 1.0 |
"Tissue compliance meter measurements of the treated breast compared to the non-treated breast were obtained at 18 months post-radiation therapy. Tissue compliance simply means how soft and pliable the breast tissue is when force is applied to it.~One physician would hold the tissue compliance meter (TCM) against the participant's skin. A standard amount of force would be applied. A second physician would read the displacement scale for a specific set of areas on the breast. The range of the scale was 0 to 60 milimeters (mm). The physician's were blineded to the participant's intervention at the time of measurement.~The final value is the difference between the untreated and the treated breast [untreated - treated]. The range of these differences was -3.3 to 7.0 mm." (NCT00583700)
Timeframe: 18 months post-treatment
| Intervention | milimeters (mm) (Mean) |
|---|---|
| Control Arm | 2.10 |
| Intervention: Pentoxifylline & Vitamin E | 0.88 |
4 reviews available for pentoxifylline and Necrosis
| Article | Year |
|---|---|
Acute Ischemia of the Glans Penis after Circumcision Treated with Hyperbaric Therapy and Pentoxifylline: Case Report and Revision of the Literature.
Topics: Adult; Anesthesia, Local; Bandages; Circumcision, Male; Humans; Hyperbaric Oxygenation; Ischemia; Ma | 2018 |
New paradigms in management of alcoholic hepatitis: a review.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Fecal Microbiota Transplantation; Female | 2017 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
[Prevention and treatment of flap necrosis by drugs].
Topics: Animals; Chlorpromazine; Graft Survival; Humans; Necrosis; Pentoxifylline; Reserpine; Skin; Surgical | 1990 |
1 trial available for pentoxifylline and Necrosis
| Article | Year |
|---|---|
Beneficial effects of pentoxifylline on hepatic steatosis, fibrosis and necroinflammation in patients with non-alcoholic steatohepatitis.
Topics: Administration, Oral; Adult; Alanine Transaminase; Aspartate Aminotransferases; Fatty Liver; Female; | 2007 |
41 other studies available for pentoxifylline and Necrosis
| Article | Year |
|---|---|
Resolution of radiation necrosis with bevacizumab following radiation therapy for primary CNS lymphoma.
Topics: Bevacizumab; Brain Neoplasms; Female; Humans; Lymphoma; Male; Middle Aged; Necrosis; Pentoxifylline; | 2022 |
Benefits of pentoxifylline for skin flap tissue repair in rats.
Topics: Animals; Graft Survival; Male; Necrosis; Pentoxifylline; Rats; Rats, Wistar; Skin Transplantation; S | 2020 |
Pentoxifylline Attenuates Arsenic Trioxide-Induced Cardiac Oxidative Damage in Mice.
Topics: Animals; Antineoplastic Agents; Antioxidants; Arsenic Trioxide; Cardiotoxicity; Heart Diseases; Lipi | 2021 |
Successfully treated fingertip necrosis in an infant with primary Raynaud phenomenon.
Topics: Anticoagulants; Drug Therapy, Combination; Enoxaparin; Fingers; Humans; Infant; Male; Necrosis; Nife | 2014 |
Pentoxifylline attenuates HPV-16 associated necrosis in placental trophoblasts.
Topics: Animals; Apoptosis; Blastocyst; Cell Survival; Embryo Implantation; Female; Human papillomavirus 16; | 2015 |
Histological modification in TRAM flap in rats treated with pentoxifylline.
Topics: Animals; Biopsy; Capillaries; Male; Models, Animal; Necrosis; Pentoxifylline; Platelet Aggregation I | 2014 |
Viability of randomized skin flaps-an experimental study in rats.
Topics: Animals; Drug Administration Schedule; Drug Therapy, Combination; Graft Survival; Hyaluronoglucosami | 2017 |
Functional protection of pentoxifylline against spinal cord ischemia/reperfusion injury in rabbits: necrosis and apoptosis effects.
Topics: Animals; Apoptosis; Caspase 3; Immunohistochemistry; In Situ Nick-End Labeling; Microscopy, Electron | 2008 |
Vascular perfusion abnormalities in infants with spinal muscular atrophy.
Topics: Anti-Infective Agents, Local; Anticoagulants; Aspirin; Diosmin; Female; Fingers; Heparin; Humans; In | 2009 |
Inadvertent injection of sodium tetradecyl sulfate during placement of mental nerve block: discussion of management and outcome.
Topics: Adult; Biocompatible Materials; Female; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Hyperbari | 2009 |
Pentoxifylline ameliorates glomerular basement membrane ultrastructural changes caused by gentamicin administration in rats.
Topics: Animals; Anti-Bacterial Agents; Apoptosis; Basement Membrane; Gentamicins; Kidney Diseases; Kidney G | 2009 |
Effects of pentoxyfilline and heparin on reperfusion injury island skin flaps in rats exposed to tobacco.
Topics: Animals; Anticoagulants; Dermatologic Surgical Procedures; Drug Therapy, Combination; Free Radical S | 2010 |
ANCA-positive necrotizing vasculitis and thrombotic vasculopathy induced by levamisole-adulterated cocaine: a distinctive clinicopathologic presentation.
Topics: Adrenal Cortex Hormones; Antibodies, Antineutrophil Cytoplasmic; Aspirin; Biopsy, Needle; Cocaine-Re | 2011 |
[Successful treatment of post circumcision glanular ischemia-necrosis with hyperbaric oxygen and intravenous pentoxifylline].
Topics: Child, Preschool; Circumcision, Male; Combined Modality Therapy; Humans; Hyperbaric Oxygenation; Inf | 2012 |
Experimental model of degloving injury in rats: effect of allopurinol and pentoxifylline in improving viability of avulsed flaps.
Topics: Allopurinol; Animals; Antioxidants; Cell Survival; Graft Survival; Hindlimb; Male; Necrosis; Pentoxi | 2013 |
Effect of pentoxifylline on histopathological changes in steroid-induced osteonecrosis of femoral head: experimental study in chicken.
Topics: Adipogenesis; Animals; Bone Marrow Cells; Chickens; Disease Models, Animal; Femur Head; Femur Head N | 2012 |
Nephroprotective effects of pentoxifylline in experimental myoglobinuric acute renal failure.
Topics: Acute Kidney Injury; Animals; Glomerular Mesangium; Glycerol; Kidney; Kidney Diseases; Kidney Glomer | 2002 |
Role of TNF-alpha, IL-1beta and IL-6 in the local tissue damage induced by Bothrops asper snake venom: an experimental assessment in mice.
Topics: Animals; Bothrops; Crotalid Venoms; Dose-Response Relationship, Drug; Edema; Hemorrhage; Interleukin | 2005 |
[Treatment of freezing injury].
Topics: Blood Viscosity; Cell Death; Cold Temperature; Combined Modality Therapy; Endothelium, Vascular; Foo | 2005 |
[Antinecrotic and antiischemic effect of mexidol and trental in ischemia of the skin graft].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electron Transport Complex II; Graft Surviva | 2005 |
Comparison of the effects of melatonin and pentoxifylline on carbon tetrachloride-induced liver toxicity in mice.
Topics: Animals; Antioxidants; Apoptosis; Carbon Tetrachloride; Catalase; Chemical and Drug Induced Liver In | 2006 |
The effect of pentoxifylline in treatment of skin degloving injuries: an experimental study.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Necrosis; Pentoxifylline; Pilot | 2006 |
TNF-alpha as therapeutic target in NASH: tried, but not yet proven.
Topics: Animals; Fatty Liver; Hepatitis; Humans; Liver; Liver Cirrhosis; Necrosis; Pentoxifylline; Protectiv | 2007 |
Importance of TNF-alpha in the course of acute infection with Trypanosoma cruzi: influence of its inhibition by pentoxifylline treatment.
Topics: Acute Disease; Animals; Chagas Disease; Immunohistochemistry; Mice; Mice, Inbred C3H; Necrosis; Para | 2008 |
[Liver damage due to normothermic ischemia and reperfusion in the rat. The effects of pentoxifylline pretreatment].
Topics: Animals; Drug Evaluation, Preclinical; Ischemia; Liver; Liver Diseases; Male; Necrosis; Pentoxifylli | 1995 |
Effect of pentoxifylline on tissue injury and platelet-activating factor production during ischemia-reperfusion injury.
Topics: Animals; Blood Pressure; Dogs; Female; Heart Rate; Infusions, Intravenous; Models, Cardiovascular; M | 1995 |
Pentoxifylline reduces skeletal muscle necrosis after acute hindlimb ischemia in rats.
Topics: Acute Disease; Animals; Hindlimb; Ischemia; Male; Muscles; Necrosis; Pentoxifylline; Rats; Rats, Wis | 1994 |
Role of activated macrophages in augmentation of endotoxin hepatotoxicity.
Topics: Animals; Chemical and Drug Induced Liver Injury; Endotoxins; Liver Diseases; Macrophage Activation; | 1994 |
Investigation of possible mechanisms of hepatic swelling and necrosis caused by acetaminophen in mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Cell Adhesion Molecules; Intercellular Adhesion Molecu | 1993 |
Edmund Prince Fowler Award Thesis. Evaluation of random skin flap survival in a porcine model.
Topics: Animals; Antioxidants; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Erythrocyte Deformab | 1996 |
Pentoxifylline in the treatment of radiation-related soft tissue injury: preliminary observations.
Topics: Administration, Oral; Aged; Analgesics; Anti-Bacterial Agents; Atrophy; Debridement; Dose-Response R | 1997 |
The effect of pentoxifylline on random-pattern skin-flap necrosis induced by nicotine treatment in the rat.
Topics: Analysis of Variance; Animals; Erythrocyte Deformability; Graft Survival; Necrosis; Nicotine; Nicoti | 1997 |
Prevention of adriamycin-induced skin necrosis with various free radical scavengers.
Topics: Animals; Antibiotics, Antineoplastic; Doxorubicin; Flavonoids; Free Radical Scavengers; Ginkgo bilob | 1998 |
[Disorders of the blood microcirculation in patients with suppurative-necrotic complications in diabetes mellitus and the approaches to their correction].
Topics: Adult; Aged; Chronic Disease; Combined Modality Therapy; Conjunctiva; Diabetes Mellitus, Type 1; Dia | 1998 |
Efficacy of pentoxifylline with aspirin in the treatment of frostbite in rats.
Topics: Animals; Aspirin; Cold Temperature; Drug Therapy, Combination; Female; Frostbite; Male; Necrosis; Pe | 1998 |
Effect of parenteral pentoxifylline and topical nitroglycerin on skin flap survival.
Topics: Administration, Topical; Animals; Graft Survival; Injections, Intraperitoneal; Necrosis; Nitroglycer | 1999 |
Beneficial effects of pentoxifylline pretreatment in non-heart-beating donors in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cryopreservation; Graft Survival; Hot Te | 2000 |
Lucio's phenomenon: clinical and therapeutic aspects.
Topics: Aged; Anti-Inflammatory Agents; Brazil; Disease Progression; Endothelium, Vascular; Fatal Outcome; F | 2000 |
[Use of vasoactive substances in prevention of skin necroses].
Topics: Animals; Graft Survival; Humans; Mice; Mice, Hairless; Microcirculation; Nafronyl; Necrosis; Pentoxi | 1992 |
Preliminary results of a pilot study of pentoxifylline in the treatment of late radiation soft tissue necrosis.
Topics: Adult; Aged; Aged, 80 and over; Female; Genitalia, Female; Humans; Male; Middle Aged; Mouth Mucosa; | 1990 |
The effects of pentoxifylline on random skin flap survival.
Topics: Animals; Female; Necrosis; Pentoxifylline; Postoperative Complications; Premedication; Skin; Surgica | 1989 |