pentoxifylline has been researched along with Mucositis, Oral in 11 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to assess the impact of pentoxifylline and vitamin E on the incidence and severity of radiotherapy-induced oral mucositis and dysphagia in head and neck cancer patients." | 9.30 | Pentoxifylline and vitamin E reduce the severity of radiotherapy-induced oral mucositis and dysphagia in head and neck cancer patients: a randomized, controlled study. ( El Wakeel, L; El-Hamamsy, M; Kelany, M; Saad, AS; Sayed, R, 2019) |
| "Radiation-induced acute oral mucositis is associated with inflammation and pain." | 5.62 | Early radiation-induced oral pain signaling responses are reduced with pentoxifylline treatment. ( Lai, YE; Lascelles, BDX; Marcus, KL; Nolan, MW; Price, ML; Robertson, JB, 2021) |
| "The purpose of this study was to assess the impact of pentoxifylline and vitamin E on the incidence and severity of radiotherapy-induced oral mucositis and dysphagia in head and neck cancer patients." | 5.30 | Pentoxifylline and vitamin E reduce the severity of radiotherapy-induced oral mucositis and dysphagia in head and neck cancer patients: a randomized, controlled study. ( El Wakeel, L; El-Hamamsy, M; Kelany, M; Saad, AS; Sayed, R, 2019) |
| "Pentoxifylline (PTX) is a drug shown to have beneficial anti-inflammatory effects in cancer patients, mainly through anti-TNFα mechanisms." | 3.11 | PTX Treatment of Colon Cancer: Mode of Action Based on Tumor Marker and Cytokine Kinetics. ( Baider, L; Barak, V; Meirovitz, A; Peretz, T; Stephanos, S, 2022) |
| "Pentoxifylline (PTX) is a drug that has been shown to have multiple beneficial effects in cancer patients through its anti-inflammatory properties." | 3.01 | Effect of pentoxifylline on colon cancer patients treated with chemotherapy (Part I). ( Baider, L; Barak, V; Meirovitz, A; Peretz, T; Stephanos, S, 2021) |
| "Oral mucositis is a frequent side effect of cancer therapy." | 2.68 | A double-blind, randomized, placebo-controlled, crossover trial of pentoxifylline for the prevention of chemotherapy-induced oral mucositis. ( Burkhead, T; Garewal, HS; Koenig, LM; Vaughn, B; Verdi, CJ, 1995) |
| "Radiation-induced acute oral mucositis is associated with inflammation and pain." | 1.62 | Early radiation-induced oral pain signaling responses are reduced with pentoxifylline treatment. ( Lai, YE; Lascelles, BDX; Marcus, KL; Nolan, MW; Price, ML; Robertson, JB, 2021) |
| "Oral mucositis is a frequent early side effect of radio(chemo)therapy of head-and-neck malignancies." | 1.42 | Modulation of radiation-induced oral mucositis by pentoxifylline: preclinical studies. ( Bozsaky, E; Dörr, W; Gruber, S; Haagen, J; Habelt, B; Puttrich, M; Schmidt, M; Wolfram, K, 2015) |
| "Oral mucositis is a frequent side-effect of cancer therapy." | 1.33 | Effects of the tumour necrosis factor-alpha inhibitors pentoxifylline and thalidomide in short-term experimental oral mucositis in hamsters. ( Augusto, RF; Brito, GA; Cunha, FQ; Falcão, BA; Leitão, BT; Lima, V; Rebouças, CG; Ribeiro, RA; Souza, ML, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Meirovitz, A | 2 |
| Baider, L | 2 |
| Peretz, T | 2 |
| Stephanos, S | 2 |
| Barak, V | 2 |
| Sayed, R | 1 |
| El Wakeel, L | 1 |
| Saad, AS | 1 |
| Kelany, M | 1 |
| El-Hamamsy, M | 1 |
| Price, ML | 1 |
| Lai, YE | 1 |
| Marcus, KL | 1 |
| Robertson, JB | 1 |
| Lascelles, BDX | 1 |
| Nolan, MW | 1 |
| Gruber, S | 3 |
| Schmidt, M | 3 |
| Bozsaky, E | 3 |
| Wolfram, K | 2 |
| Haagen, J | 2 |
| Habelt, B | 2 |
| Puttrich, M | 2 |
| Dörr, W | 3 |
| Moura, JF | 1 |
| Mota, JM | 1 |
| Leite, CA | 1 |
| Wong, DV | 1 |
| Bezerra, NP | 1 |
| Brito, GA | 2 |
| Lima, V | 2 |
| Cunha, FQ | 2 |
| Ribeiro, RA | 2 |
| Hamedinger, D | 1 |
| Roitinger, E | 1 |
| Schwarz, K | 1 |
| Rebouças, CG | 1 |
| Falcão, BA | 1 |
| Augusto, RF | 1 |
| Souza, ML | 1 |
| Leitão, BT | 1 |
| Verdi, CJ | 1 |
| Garewal, HS | 1 |
| Koenig, LM | 1 |
| Vaughn, B | 1 |
| Burkhead, T | 1 |
| Ferrà, C | 1 |
| de Sanjosé, S | 1 |
| Lastra, CF | 1 |
| Martí, F | 1 |
| Mariño, EL | 1 |
| Sureda, A | 1 |
| Brunet, S | 1 |
| Gallardo, D | 1 |
| Berlanga, JJ | 1 |
| García, J | 1 |
| Grañena, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Study Evaluating the Anticancer Effect of Pentoxiphylline in Patients With Metastatic Colorectal Cancer[NCT06115174] | Phase 4 | 44 participants (Anticipated) | Interventional | 2023-11-01 | Not yet recruiting | ||
| The Effect of Alpha Lipoic Acid on the Incidence and Severity of Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients[NCT05023863] | Phase 2/Phase 3 | 70 participants (Anticipated) | Interventional | 2021-09-01 | Not yet recruiting | ||
| The Impact of Pentoxifylline and Vitamin E on The Incidence and Severity of Radiotherapy- Induced Oral Mucositis and Dysphagia in Patients With Head and Neck Cancer[NCT02397486] | Phase 2 | 60 participants (Actual) | Interventional | 2015-05-02 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for pentoxifylline and Mucositis, Oral
| Article | Year |
|---|---|
Effect of pentoxifylline on colon cancer patients treated with chemotherapy (Part I).
Topics: Aged; Antineoplastic Agents; Cachexia; Colonic Neoplasms; Disease Progression; Female; Fluorouracil; | 2021 |
PTX Treatment of Colon Cancer: Mode of Action Based on Tumor Marker and Cytokine Kinetics.
Topics: Anti-Inflammatory Agents; Biomarkers, Tumor; Carcinoembryonic Antigen; Colonic Neoplasms; Cytokines; | 2022 |
Pentoxifylline and vitamin E reduce the severity of radiotherapy-induced oral mucositis and dysphagia in head and neck cancer patients: a randomized, controlled study.
Topics: Aged; Antioxidants; Deglutition Disorders; Female; Head and Neck Neoplasms; Humans; Male; Middle Age | 2019 |
Pentoxifylline and vitamin E reduce the severity of radiotherapy-induced oral mucositis and dysphagia in head and neck cancer patients: a randomized, controlled study.
Topics: Aged; Antioxidants; Deglutition Disorders; Female; Head and Neck Neoplasms; Humans; Male; Middle Age | 2019 |
Pentoxifylline and vitamin E reduce the severity of radiotherapy-induced oral mucositis and dysphagia in head and neck cancer patients: a randomized, controlled study.
Topics: Aged; Antioxidants; Deglutition Disorders; Female; Head and Neck Neoplasms; Humans; Male; Middle Age | 2019 |
Pentoxifylline and vitamin E reduce the severity of radiotherapy-induced oral mucositis and dysphagia in head and neck cancer patients: a randomized, controlled study.
Topics: Aged; Antioxidants; Deglutition Disorders; Female; Head and Neck Neoplasms; Humans; Male; Middle Age | 2019 |
A double-blind, randomized, placebo-controlled, crossover trial of pentoxifylline for the prevention of chemotherapy-induced oral mucositis.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cross-Over St | 1995 |
Pentoxifylline, ciprofloxacin and prednisone failed to prevent transplant-related toxicities in bone marrow transplant recipients and were associated with an increased incidence of infectious complications.
Topics: Adolescent; Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Bacterial Infections; Bone Marro | 1997 |
6 other studies available for pentoxifylline and Mucositis, Oral
| Article | Year |
|---|---|
Early radiation-induced oral pain signaling responses are reduced with pentoxifylline treatment.
Topics: Animals; Capsaicin; Histamine; Mice; Pain; Pentoxifylline; Pilot Projects; Prospective Studies; Radi | 2021 |
Modulation of radiation-induced oral mucositis by pentoxifylline: preclinical studies.
Topics: Animals; Disease Models, Animal; Dose Fractionation, Radiation; Female; Male; Mice; Mice, Inbred C3H | 2015 |
A novel model of megavoltage radiation-induced oral mucositis in hamsters: Role of inflammatory cytokines and nitric oxide.
Topics: Animals; Cobalt Radioisotopes; Cricetinae; Cytokines; Disease Models, Animal; Guanidines; Head and N | 2015 |
Local hypoxia in oral mucosa (mouse) during daily fractionated irradiation - Effect of pentoxifylline.
Topics: Analysis of Variance; Animals; Cell Count; Demulcents; Disease Models, Animal; Dose Fractionation, R | 2015 |
Early inflammatory changes in radiation-induced oral mucositis : Effect of pentoxifylline in a mouse model.
Topics: Animals; Disease Models, Animal; Dose Fractionation, Radiation; Inflammation Mediators; Mice; Mice, | 2017 |
Effects of the tumour necrosis factor-alpha inhibitors pentoxifylline and thalidomide in short-term experimental oral mucositis in hamsters.
Topics: Abscess; Animals; Antimetabolites, Antineoplastic; Cricetinae; Disease Models, Animal; Edema; Erythe | 2005 |