Page last updated: 2024-11-02

pentoxifylline and Malaria

pentoxifylline has been researched along with Malaria in 6 studies

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
"A combination therapy was tested consisting of chloroquine and interferon-gamma (IFN-gamma) in the late phase of blood-stage Plasmodium vinckei malaria in BALB/c mice."7.68Interferon-gamma induced lethality in the late phase of Plasmodium vinckei malaria despite effective parasite clearance by chloroquine. ( Bienzle, U; Chaves, MF; Kremsner, PG; Neifer, S; Rudolph, R, 1992)
"Pentoxifylline, a widely used methylxanthine, was tested for its capacity to prevent cerebral malaria (CM) in Plasmodium berghei ANKA-infected CBA/Ca mice."7.68Pentoxifylline prevents murine cerebral malaria. ( Bienzle, U; Grundmann, H; Hegenscheid, B; Kremsner, PG; Neifer, S; Sahlmüller, G; Sliwa, K, 1991)
"A combination therapy was tested consisting of chloroquine and interferon-gamma (IFN-gamma) in the late phase of blood-stage Plasmodium vinckei malaria in BALB/c mice."3.68Interferon-gamma induced lethality in the late phase of Plasmodium vinckei malaria despite effective parasite clearance by chloroquine. ( Bienzle, U; Chaves, MF; Kremsner, PG; Neifer, S; Rudolph, R, 1992)
"Pentoxifylline, a widely used methylxanthine, was tested for its capacity to prevent cerebral malaria (CM) in Plasmodium berghei ANKA-infected CBA/Ca mice."3.68Pentoxifylline prevents murine cerebral malaria. ( Bienzle, U; Grundmann, H; Hegenscheid, B; Kremsner, PG; Neifer, S; Sahlmüller, G; Sliwa, K, 1991)
"Pentoxifylline (PTX) is a methylxanthine with selective anti-inflammatory activity."2.39Pentoxifylline in severe inflammatory response syndrome. ( Graninger, W; Wenisch, C, 1995)
"Cerebral malaria is associated with the circulating levels of tumour necrosis factor alpha (TNF-α) and transforming growth factor β (TGF-β), but association between these two cytokines and implications in splenocyte apoptosis remain largely obscured."1.39Splenocyte apoptosis in Plasmodium berghei ANKA infection: possible role of TNF-α and TGF-β. ( Bhattacharyya, A; Keswani, T, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keswani, T1
Bhattacharyya, A1
Graninger, W2
Wenisch, C1
Voza, T1
Gautret, P1
Renia, L1
Gantier, JC1
Lombard, MN1
Chabaud, AG1
Landau, I1
Kremsner, PG2
Neifer, S2
Chaves, MF1
Rudolph, R1
Bienzle, U2
Grundmann, H1
Sliwa, K1
Sahlmüller, G1
Hegenscheid, B1
Thalhammer, F1
Locker, G1

Reviews

1 review available for pentoxifylline and Malaria

ArticleYear
Pentoxifylline in severe inflammatory response syndrome.
    Journal of cardiovascular pharmacology, 1995, Volume: 25 Suppl 2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammation; Malaria; Pentoxifylline

1995

Other Studies

5 other studies available for pentoxifylline and Malaria

ArticleYear
Splenocyte apoptosis in Plasmodium berghei ANKA infection: possible role of TNF-α and TGF-β.
    Parasite immunology, 2013, Volume: 35, Issue:2

    Topics: Animals; Apoptosis; Benzamides; Cell Survival; Dioxoles; Fas Ligand Protein; Flow Cytometry; Gene Ex

2013
Variation in murid Plasmodium desequestration and its modulation by stress and pentoxifylline.
    Parasitology research, 2002, Volume: 88, Issue:4

    Topics: Animals; Disease Models, Animal; Hematologic Agents; Malaria; Mice; Parasitemia; Pentoxifylline; Pla

2002
Interferon-gamma induced lethality in the late phase of Plasmodium vinckei malaria despite effective parasite clearance by chloroquine.
    European journal of immunology, 1992, Volume: 22, Issue:11

    Topics: Animals; Arginine; Chloroquine; Deferoxamine; Female; Immunization; Interferon-gamma; Liver; Malaria

1992
Pentoxifylline prevents murine cerebral malaria.
    The Journal of infectious diseases, 1991, Volume: 164, Issue:3

    Topics: Animals; Antigens, Protozoan; Blotting, Northern; Brain; Female; Macrophages; Malaria; Mice; Mice, I

1991
Pentoxifylline in cerebral malaria.
    The Journal of infectious diseases, 1991, Volume: 164, Issue:4

    Topics: Adult; Animals; Brain Diseases; Humans; Malaria; Male; Pentoxifylline; Plasmodium falciparum; Tumor

1991