pentoxifylline has been researched along with Lung Neoplasms in 25 studies
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentoxifylline (PTX) has been reported to have both direct and indirect anti-tumor effects in experimental tumor models." | 5.30 | The effect of pentoxifylline on spontaneous and experimental metastasis of the mouse Neuro2a neuroblastoma. ( Amirkhosravi, A; Biggerstaff, J; Francis, JL; Malik, Z; May, K; Warnes, G, 1997) |
| "To investigate whether the application of vitamin E with or without pentoxifylline could modify the development of radiation-induced pulmonary fibrosis." | 3.74 | Vitamin E protects against the development of radiation-induced pulmonary fibrosis in rats. ( Altug, T; Arbak, S; Bese, NS; Munzuroglu, F; Ober, A; Sut, N; Uslu, B; Yesiladali, G, 2007) |
| " In the present study, enhancement in the antimetastatic activity of etoposide (ETP) by encapsulation in sterically stabilized liposomes was evaluated in the murine experimental B16F10 melanoma model." | 3.72 | Sterically stabilized etoposide liposomes: evaluation of antimetastatic activity and its potentiation by combination with sterically stabilized pentoxifylline liposomes in mice. ( Gude, RP; Nagarsenker, MS; Rao, SG; Sant, VP, 2003) |
| "In the present study, we have examined the antimetastatic effect of flurbiprofen, a nonsteroidal antiinflammatory drug, on spontaneous metastases formation in mice bearing Lewis lung carcinoma and these results were compared with effects of other inhibitors of platelet function (mopidamole, dipyridamole, pentoxifylline)." | 3.67 | Antimetastatic effect of flurbiprofen and other platelet aggregation inhibitors. ( Grimová, J; Kacerovská, H; Mamytbeková, A; Rezábek, K; Svobodová, J, 1986) |
| "Pentoxifylline (Trental), a phosphodiesterase inhibitor with platelet aggregation inhibitory effect, was shown to decrease spontaneous metastases in a Wilms' tumor model in Furth-Wistar rats and in neuroblastoma C1300 in A/J mice." | 3.66 | Studies on platelet aggregation inhibitors in vivo. VIII. Effect of pentoxifylline on spontaneous tumor metastasis. ( Ambrus, JL; Cohen, H; Gastpar, H; Gordon, S; Murphy, GP; Sciandra, J; Williams, P; Witul, M, 1979) |
| " We recommend the prophylactic use of Ptx, finding it to be safe and effective." | 2.71 | Pentoxifylline in prevention of radiation-induced lung toxicity in patients with breast and lung cancer: a double-blind randomized trial. ( Atavci, S; Egehan, I; Kitapci, M; Ozturk, B, 2004) |
| "Pentoxifylline (PTX) has pharmacological properties that suggest potential utility as a radiation sensitizer, and preclinical animal studies have been promising." | 2.69 | A phase II evaluation of pentoxifylline combined with radiation in the treatment of brain metastases. ( Harrison, BR; Johnson, FE; McKirgan, LW; Raju, PI; Roy, TK; Virgo, KS, 1998) |
| "Although no lung metastasis was observed in the rats killed at the end of the period of carcinogen exposure, lung metastasis was found in 100% of animals in all the groups at the end of the experiment." | 1.32 | Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma. ( Futakuchi, M; Ogawa, K; Shirai, T; Takahashi, S; Tamano, S, 2004) |
| "Pentoxifylline has been shown to exhibit anti-metastatic activity by inhibiting homing of B16F10 melanoma cells in the murine experimental metastasis model." | 1.31 | Enhancement of anti-metastatic activity of pentoxifylline by encapsulation in conventional liposomes and sterically stabilized liposomes in murine experimental B16F10 melanoma model. ( Gude, RP; Nagarsenker, MS; Rao, SG; Sant, VP, 2000) |
| "Pentoxifylline (PTX) has been reported to have both direct and indirect anti-tumor effects in experimental tumor models." | 1.30 | The effect of pentoxifylline on spontaneous and experimental metastasis of the mouse Neuro2a neuroblastoma. ( Amirkhosravi, A; Biggerstaff, J; Francis, JL; Malik, Z; May, K; Warnes, G, 1997) |
| "B16 melanoma has proved to be an ideal model for investigating metastasis." | 1.29 | Inhibition of lung homing of B16F10 by pentoxifylline, a microfilament depolymerizing agent. ( Gude, RP; Ingle, AD; Rao, SG, 1996) |
| " In the present experiment pentoxifylline appears to be a highly effective platelet aggregation inhibitor: a dose-response curve is apparent in monkey between 6 and 24 mg/kg i." | 1.26 | Effect of phosphodiesterase inhibitors on platelet aggregation and tumor metastasis. ( Ambrus, CM; Ambrus, JL; Gastpar, H, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (16.00) | 18.7374 |
| 1990's | 8 (32.00) | 18.2507 |
| 2000's | 13 (52.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andela, VB | 1 |
| Gingold, BI | 1 |
| Souza, MD | 1 |
| O'Keefe, RJ | 1 |
| Puzas, EJ | 1 |
| Schwarz, EM | 1 |
| Rosier, RN | 1 |
| Sant, VP | 2 |
| Nagarsenker, MS | 2 |
| Rao, SG | 3 |
| Gude, RP | 5 |
| Ozturk, B | 1 |
| Egehan, I | 1 |
| Atavci, S | 1 |
| Kitapci, M | 1 |
| Futakuchi, M | 1 |
| Ogawa, K | 1 |
| Tamano, S | 1 |
| Takahashi, S | 1 |
| Shirai, T | 1 |
| Lazarczyk, M | 1 |
| Grzela, T | 1 |
| Niderla, J | 1 |
| Lazarczyk, MA | 1 |
| Milewski, L | 1 |
| Dziunycz, P | 1 |
| Skopinski, P | 1 |
| Golab, J | 1 |
| Misirlioglu, CH | 2 |
| Erkal, H | 1 |
| Elgin, Y | 1 |
| Ugur, I | 1 |
| Altundag, K | 2 |
| Bese, NS | 1 |
| Munzuroglu, F | 1 |
| Uslu, B | 1 |
| Arbak, S | 1 |
| Yesiladali, G | 1 |
| Sut, N | 1 |
| Altug, T | 1 |
| Ober, A | 1 |
| Dua, P | 1 |
| Ingle, A | 2 |
| Demirkasimoglu, T | 1 |
| Kucukplakci, B | 1 |
| Sanri, E | 1 |
| Jellett, L | 1 |
| Harrison, C | 1 |
| McAleese, J | 1 |
| Ratheesh, A | 1 |
| Ambrus, JL | 2 |
| Ambrus, CM | 1 |
| Gastpar, H | 2 |
| Ishibashi, T | 1 |
| Yamada, H | 1 |
| Harada, S | 1 |
| Harada, Y | 1 |
| Miyazaki, N | 1 |
| Takamoto, M | 1 |
| Watanabe, K | 1 |
| Lai, SL | 1 |
| Hwang, J | 1 |
| Perng, RP | 1 |
| Whang-Peng, J | 1 |
| Stewart, DJ | 1 |
| Evans, WK | 1 |
| Logan, D | 1 |
| Balibrea-Cantero, JL | 1 |
| Arias-Diaz, J | 1 |
| Garcia, C | 1 |
| Torres-Melero, J | 1 |
| Simon, C | 1 |
| Rodriguez, JM | 1 |
| Vara, E | 1 |
| Ingle, AD | 1 |
| Amirkhosravi, A | 1 |
| Warnes, G | 1 |
| Biggerstaff, J | 1 |
| Malik, Z | 1 |
| May, K | 1 |
| Francis, JL | 1 |
| Johnson, FE | 1 |
| Harrison, BR | 1 |
| McKirgan, LW | 1 |
| Raju, PI | 1 |
| Roy, TK | 1 |
| Virgo, KS | 1 |
| Kwon, HC | 1 |
| Kim, SK | 1 |
| Chung, WK | 1 |
| Cho, MJ | 1 |
| Kim, JS | 2 |
| Moon, SR | 1 |
| Park, WY | 1 |
| Ahn, SJ | 1 |
| Oh, YK | 1 |
| Yun, HG | 1 |
| Na, BS | 1 |
| Gordon, S | 1 |
| Witul, M | 1 |
| Cohen, H | 1 |
| Sciandra, J | 1 |
| Williams, P | 1 |
| Murphy, GP | 1 |
| Dezube, BJ | 1 |
| Fridovich-Keil, JL | 1 |
| Bouvard, I | 1 |
| Lange, RF | 1 |
| Pardee, AB | 1 |
| Ishida, S | 1 |
| Fujiuchi, S | 1 |
| Akiba, Y | 1 |
| Osanai, S | 1 |
| Tsuji, T | 1 |
| Nakano, H | 1 |
| Matsumoto, H | 1 |
| Ohosaki, Y | 1 |
| Fujikane, T | 1 |
| Onodera, S | 1 |
| Mamytbeková, A | 1 |
| Rezábek, K | 1 |
| Kacerovská, H | 1 |
| Grimová, J | 1 |
| Svobodová, J | 1 |
5 trials available for pentoxifylline and Lung Neoplasms
| Article | Year |
|---|---|
Pentoxifylline in prevention of radiation-induced lung toxicity in patients with breast and lung cancer: a double-blind randomized trial.
Topics: Adult; Breast Neoplasms; Female; Humans; Lung Diseases; Lung Neoplasms; Male; Middle Aged; Pentoxify | 2004 |
Effect of concomitant use of pentoxifylline and alpha-tocopherol with radiotherapy on the clinical outcome of patients with stage IIIB non-small cell lung cancer: a randomized prospective clinical trial.
Topics: Adult; Aged; alpha-Tocopherol; Antioxidants; Carcinoma, Non-Small-Cell Lung; Combined Modality Thera | 2006 |
Pentoxifylline and alpha-tocopherol in prevention of radiation-induced lung toxicity in patients with lung cancer.
Topics: Adult; Aged; alpha-Tocopherol; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Combined Modal | 2007 |
A phase II evaluation of pentoxifylline combined with radiation in the treatment of brain metastases.
Topics: Adult; Aged; Arrhythmias, Cardiac; Brain Neoplasms; Combined Modality Therapy; Dizziness; Female; He | 1998 |
Effect of pentoxifylline on radiation response of non-small cell lung cancer: a phase III randomized multicenter trial.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Dose Fractionation, Radiation; Female; Follow-Up Studies; Huma | 2000 |
20 other studies available for pentoxifylline and Lung Neoplasms
| Article | Year |
|---|---|
Clinical relevance of increased retinoid and cAMP transcriptional programs in tumor cells rendered non-malignant by dominant negative inhibition of NFkappaB.
Topics: Animals; Antineoplastic Agents; Collagen; Cyclic AMP; Disease Progression; Drug Combinations; Female | 2003 |
Sterically stabilized etoposide liposomes: evaluation of antimetastatic activity and its potentiation by combination with sterically stabilized pentoxifylline liposomes in mice.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; E | 2003 |
Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma.
Topics: Acetylcysteine; Animals; Aspirin; Blotting, Western; Carcinogens; Diethylnitrosamine; E-Selectin; En | 2004 |
Differential influence of pentoxifylline on murine colon adenocarcinoma- and melanoma-derived metastatic tumor development in lungs.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Lung Neoplasms; Melanoma; Mice; Mice, Inbred BALB C; Pen | 2004 |
Vitamin E protects against the development of radiation-induced pulmonary fibrosis in rats.
Topics: Animals; Antioxidants; Dietary Supplements; Drug Therapy, Combination; Female; Fibrosis; Free Radica | 2007 |
Suramin augments the antitumor and antimetastatic activity of pentoxifylline in B16F10 melanoma.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols | 2007 |
Letter to editor. Re: "Effect of concomitant use of pentoxifylline (PTX) and alpha-tocopherol with radiotherapy on the clinical outcome of patients with stage IIIB non-small cell lung cancer".
Topics: alpha-Tocopherol; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Drug Therapy, Combinati | 2007 |
Pentoxifylline modulates cell surface integrin expression and integrin mediated adhesion of B16F10 cells to extracellular matrix components.
Topics: Animals; Cell Adhesion; Cell Line, Tumor; Fibronectins; Integrins; Lung Neoplasms; Melanoma, Experim | 2007 |
Effect of phosphodiesterase inhibitors on platelet aggregation and tumor metastasis.
Topics: Adenocarcinoma; Adenosine Diphosphate; Animals; Carcinoma, Ehrlich Tumor; Female; Head and Neck Neop | 1981 |
Distant metastasis facilitated by BCG: spread of tumour cells injected in the BCG-primed site.
Topics: Animals; BCG Vaccine; Blood Cell Count; Erythrocytes; Female; Fibrosarcoma; Immunity; Iodine Radiois | 1980 |
Modulation of cisplatin resistance in acquired-resistant nonsmall cell lung cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lu | 1995 |
Addition of pentoxifylline plus nifedipine to chemotherapy in patients with cisplatin-resistant cancers of the lung and other sites.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Drug Evaluation; Drug R | 1994 |
Effect of pentoxifylline on the inhibition of surfactant synthesis induced by TNF-alpha in human type II pneumocytes.
Topics: Adult; Analysis of Variance; Drug Evaluation, Preclinical; Humans; In Vitro Techniques; Lung; Lung N | 1994 |
Inhibition of lung homing of B16F10 by pentoxifylline, a microfilament depolymerizing agent.
Topics: Actin Cytoskeleton; Animals; Female; Lung Neoplasms; Male; Melanoma, Experimental; Mice; Mice, Inbre | 1996 |
The effect of pentoxifylline on spontaneous and experimental metastasis of the mouse Neuro2a neuroblastoma.
Topics: Animals; Carcinogenicity Tests; Cell Adhesion; Cell Cycle; Cell Division; Cell Membrane; Female; Fib | 1997 |
Enhancement of anti-metastatic activity of pentoxifylline by encapsulation in conventional liposomes and sterically stabilized liposomes in murine experimental B16F10 melanoma model.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Compounding; Female; Liposom | 2000 |
Studies on platelet aggregation inhibitors in vivo. VIII. Effect of pentoxifylline on spontaneous tumor metastasis.
Topics: Adenocarcinoma; Animals; Lung Neoplasms; Male; Mice; Mice, Inbred A; Mice, Inbred BALB C; Neoplasm M | 1979 |
Pentoxifylline and wellbeing in patients with cancer.
Topics: Adult; Breast Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Humans; Lung Neoplas | 1990 |
[Combination effect of pentoxifylline and etoposide on a human lung cancer cell line].
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Etoposide; Humans; Lung Neoplasms; P | 1991 |
Antimetastatic effect of flurbiprofen and other platelet aggregation inhibitors.
Topics: Animals; Antineoplastic Agents; Dipyridamole; Flurbiprofen; Lung Neoplasms; Male; Mice; Mice, Inbred | 1986 |