pentoxifylline has been researched along with Leukocytopenia in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The xanthine derivative pentoxifylline (POF, Trental) and its metabolically more stable structural analogues, HWA 138 and HWA 448, were compared for their capacity to prevent leukopenia provoked in mice by injection of bacterial lipopolysaccharide (LPS)." | 3.67 | The role of prostacyclin in the protective effects of pentoxifylline and other xanthine derivatives in endotoxin action in mice. ( Schade, UF, 1989) |
| "Pentoxifylline (PTX) is a drug that has been shown to have multiple beneficial effects in cancer patients through its anti-inflammatory properties." | 3.01 | Effect of pentoxifylline on colon cancer patients treated with chemotherapy (Part I). ( Baider, L; Barak, V; Meirovitz, A; Peretz, T; Stephanos, S, 2021) |
| " Thirty-five previously treated advanced breast cancer patients received 70 cycles (median, 2 cycles/patient; range, 1-6) of 1600 mg of oral sustained release pentoxifylline every 8 h for 4 doses in combination with escalating doses of i." | 2.68 | Dose escalation of N,N',N"-triethylenethiophosphoramide combined with pentoxifylline for advanced breast cancer. ( Cap, B; Dezube, BJ; Hayes, DF; Henderson, IC; Shapiro, CL; Tretyakov, O; Wright, J, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Cottam, HB | 1 |
| Shih, H | 1 |
| Tehrani, LR | 1 |
| Wasson, DB | 1 |
| Carson, DA | 1 |
| Meirovitz, A | 1 |
| Baider, L | 1 |
| Peretz, T | 1 |
| Stephanos, S | 1 |
| Barak, V | 1 |
| Zimmerman, A | 1 |
| Clemens, PR | 1 |
| Tesi-Rocha, C | 1 |
| Connolly, A | 1 |
| Iannaccone, ST | 1 |
| Kuntz, N | 1 |
| Arrieta, A | 1 |
| Hache, L | 1 |
| Henricson, E | 1 |
| Hu, F | 1 |
| Mayhew, J | 1 |
| Escolar, DM | 1 |
| Zabel, P | 1 |
| Schade, FU | 1 |
| Schlaak, M | 1 |
| Hoffmann, H | 1 |
| Weis, M | 1 |
| Frank, G | 1 |
| Birg, A | 1 |
| Schönharting, MM | 1 |
| Jochum, M | 1 |
| Shapiro, CL | 1 |
| Dezube, BJ | 1 |
| Tretyakov, O | 1 |
| Wright, J | 1 |
| Cap, B | 1 |
| Henderson, IC | 1 |
| Hayes, DF | 1 |
| Schade, UF | 2 |
| von der Bosch, J | 1 |
| Schönharting, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Study Evaluating the Anticancer Effect of Pentoxiphylline in Patients With Metastatic Colorectal Cancer[NCT06115174] | Phase 4 | 44 participants (Anticipated) | Interventional | 2023-11-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pentoxifylline and Leukocytopenia
| Article | Year |
|---|---|
Inhibition of endogenous TNF formation by pentoxifylline.
Topics: Animals; Cells, Cultured; Cytokines; Humans; Indomethacin; Kidney Transplantation; Leukopenia; Lipop | 1993 |
3 trials available for pentoxifylline and Leukocytopenia
| Article | Year |
|---|---|
Effect of pentoxifylline on colon cancer patients treated with chemotherapy (Part I).
Topics: Aged; Antineoplastic Agents; Cachexia; Colonic Neoplasms; Disease Progression; Female; Fluorouracil; | 2021 |
Liquid formulation of pentoxifylline is a poorly tolerated treatment for duchenne dystrophy.
Topics: Administration, Oral; Child; Child, Preschool; Gastrointestinal Diseases; Humans; Leukopenia; Male; | 2011 |
Dose escalation of N,N',N"-triethylenethiophosphoramide combined with pentoxifylline for advanced breast cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Dose-Response Relationship, Dr | 1995 |
4 other studies available for pentoxifylline and Leukocytopenia
| Article | Year |
|---|---|
Substituted xanthines, pteridinediones, and related compounds as potential antiinflammatory agents. Synthesis and biological evaluation of inhibitors of tumor necrosis factor alpha.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Anti-I | 1996 |
Amelioration of endotoxin-induced acute lung injury in pigs by HWA 138 and A 80 2715: new analogs of pentoxifylline.
Topics: Animals; Bronchodilator Agents; Hemodynamics; Infusions, Intravenous; Leukocyte Count; Leukopenia; L | 1995 |
Pentoxifylline increases survival of mice in endotoxic shock.
Topics: Animals; Epoprostenol; Female; Indomethacin; Leukopenia; Lipopolysaccharides; Mice; Pentoxifylline; | 1989 |
The role of prostacyclin in the protective effects of pentoxifylline and other xanthine derivatives in endotoxin action in mice.
Topics: Animals; Endotoxins; Epoprostenol; Female; Indomethacin; Leukopenia; Lipopolysaccharides; Mice; Pent | 1989 |