pentoxifylline has been researched along with Leukemia in 3 studies
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bravo-Cuellar, A | 2 |
| Hernández-Flores, G | 2 |
| Lerma-Díaz, JM | 2 |
| Domínguez-Rodríguez, JR | 2 |
| Jave-Suárez, LF | 2 |
| De Célis-Carrillo, R | 1 |
| Aguilar-Lemarroy, A | 2 |
| Gómez-Lomeli, P | 1 |
| Ortiz-Lazareno, PC | 2 |
| Gómez-Contreras, P | 1 |
| Cervantes-Munguía, R | 1 |
| Scott-Algara, D | 1 |
| Biddle, W | 1 |
| Ambrus, CM | 1 |
| Gastpar, H | 1 |
| Ambrus, JL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Enhancing Effect on Tumour Apoptosis With the Combined Use of Pentoxifylline Plus Chemotherapeutical Agents in Pediatrics and AYA Patients With Hodgkin´s Lymphoma[NCT05490953] | Phase 4 | 30 participants (Anticipated) | Interventional | 2022-07-11 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for pentoxifylline and Leukemia
| Article | Year |
|---|---|
Pentoxifylline and the proteasome inhibitor MG132 induce apoptosis in human leukemia U937 cells through a decrease in the expression of Bcl-2 and Bcl-XL and phosphorylation of p65.
Topics: Apoptosis; bcl-X Protein; Carrier Proteins; Gene Expression Regulation, Leukemic; Humans; Intracellu | 2013 |
In vivo and in vitro sensitization of leukemic cells to adriamycin-induced apoptosis by pentoxifylline. Involvement of caspase cascades and IkappaBalpha phosphorylation.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspases; Doxorubicin; Humans; I-kappa | 2006 |
Antineoplastic effect of the xanthine derivative Trental.
Topics: B-Lymphocytes; Burkitt Lymphoma; Cell Line; Combined Modality Therapy; DNA; Humans; Interferon Type | 1984 |