Page last updated: 2024-11-02

pentoxifylline and Leukemia

pentoxifylline has been researched along with Leukemia in 3 studies

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bravo-Cuellar, A2
Hernández-Flores, G2
Lerma-Díaz, JM2
Domínguez-Rodríguez, JR2
Jave-Suárez, LF2
De Célis-Carrillo, R1
Aguilar-Lemarroy, A2
Gómez-Lomeli, P1
Ortiz-Lazareno, PC2
Gómez-Contreras, P1
Cervantes-Munguía, R1
Scott-Algara, D1
Biddle, W1
Ambrus, CM1
Gastpar, H1
Ambrus, JL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Enhancing Effect on Tumour Apoptosis With the Combined Use of Pentoxifylline Plus Chemotherapeutical Agents in Pediatrics and AYA Patients With Hodgkin´s Lymphoma[NCT05490953]Phase 430 participants (Anticipated)Interventional2022-07-11Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for pentoxifylline and Leukemia

ArticleYear
Pentoxifylline and the proteasome inhibitor MG132 induce apoptosis in human leukemia U937 cells through a decrease in the expression of Bcl-2 and Bcl-XL and phosphorylation of p65.
    Journal of biomedical science, 2013, Feb-28, Volume: 20

    Topics: Apoptosis; bcl-X Protein; Carrier Proteins; Gene Expression Regulation, Leukemic; Humans; Intracellu

2013
In vivo and in vitro sensitization of leukemic cells to adriamycin-induced apoptosis by pentoxifylline. Involvement of caspase cascades and IkappaBalpha phosphorylation.
    Immunology letters, 2006, Mar-15, Volume: 103, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspases; Doxorubicin; Humans; I-kappa

2006
Antineoplastic effect of the xanthine derivative Trental.
    Journal of medicine, 1984, Volume: 15, Issue:5-6

    Topics: B-Lymphocytes; Burkitt Lymphoma; Cell Line; Combined Modality Therapy; DNA; Humans; Interferon Type

1984