pentoxifylline has been researched along with Leprosy in 5 studies
Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Type 2 lepra reaction (T2R) is a difficult-to-manage condition in leprosy, and an effective and safe steroid-sparing agent is needed for its management." | 2.80 | Effectiveness and safety of clofazimine and pentoxifylline in type 2 lepra reaction: a double-blind, randomized, controlled study. ( Bandyopadhyay, D; Das, NK; Roy, K; Sil, A, 2015) |
| "Pentoxifylline (PTX) is a methylxanthine derivative with a variety of anti-inflammatory effects." | 2.44 | Pentoxifylline: a drug with wide spectrum applications in dermatology. ( Zargari, O, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cerqueira, SRPS | 1 |
| Deps, PD | 1 |
| Cunha, DV | 1 |
| Bezerra, NVF | 1 |
| Barroso, DH | 1 |
| Pinheiro, ABS | 1 |
| Pillegi, GS | 1 |
| Repsold, TAR | 1 |
| Kurizky, PS | 1 |
| Collin, SM | 1 |
| Gomes, CM | 1 |
| Roy, K | 1 |
| Sil, A | 1 |
| Das, NK | 1 |
| Bandyopadhyay, D | 1 |
| Zargari, O | 1 |
| Teles, RM | 1 |
| Moraes, MO | 1 |
| Geraldo, NT | 1 |
| Salles, AM | 1 |
| Sarno, EN | 2 |
| Sampaio, EP | 2 |
| Hernandez, MO | 1 |
| Neves, I | 1 |
| Sales, JS | 1 |
| Carvalho, DS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Topical Pentoxifylline; Metformin Versus Betamethasone in the Treatment of Alopecia Areata: a Clinical and Dermoscopic Study.[NCT06087796] | Phase 1 | 60 participants (Anticipated) | Interventional | 2023-10-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pentoxifylline and Leprosy
| Article | Year |
|---|---|
Pentoxifylline: a drug with wide spectrum applications in dermatology.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Behcet Syndrome; C | 2008 |
1 trial available for pentoxifylline and Leprosy
| Article | Year |
|---|---|
Effectiveness and safety of clofazimine and pentoxifylline in type 2 lepra reaction: a double-blind, randomized, controlled study.
Topics: Adult; Arthritis, Reactive; Clofazimine; Double-Blind Method; Female; Humans; Inflammation; Leprosta | 2015 |
3 other studies available for pentoxifylline and Leprosy
| Article | Year |
|---|---|
The influence of leprosy-related clinical and epidemiological variables in the occurrence and severity of COVID-19: A prospective real-world cohort study.
Topics: Adrenal Cortex Hormones; BCG Vaccine; Brazil; Clofazimine; Cohort Studies; COVID-19; COVID-19 Drug T | 2021 |
Differential TNFalpha mRNA regulation detected in the epidermis of leprosy patients.
Topics: Adult; Aged; Anti-Inflammatory Agents; Cytokines; Dermis; Epidermis; Female; Humans; Intercellular A | 2002 |
Induction of apoptosis in monocytes by Mycobacterium leprae in vitro: a possible role for tumour necrosis factor-alpha.
Topics: Adult; Aged; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell | 2003 |