Page last updated: 2024-11-02

pentoxifylline and Jaw Diseases

pentoxifylline has been researched along with Jaw Diseases in 8 studies

Jaw Diseases: Diseases involving the JAW.

Research Excerpts

ExcerptRelevanceReference
"The aim of this experimental study was to investigate the prophylactic effect of pentoxifylline (PTX) on medication-related osteonecrosis of the jaw (MRONJ)."7.85Preventive Effect of Phosphodiesterase Inhibitor Pentoxifylline Against Medication-Related Osteonecrosis of the Jaw: An Animal Study. ( Cumbul, A; Duygu-Capar, G; Sencift, K; Uslu, Ü; Yalcin-Ulker, GM, 2017)
"Pentoxifylline has been used to treat complications related to fibrosis for over 20 years."6.55Pentoxifylline - a review of its use in osteoradionecrosis. ( Brennan, PA; Lyons, AJ, 2017)
"To review the conservative and surgical management options of osteoradionecrosis, in particular, highlighting the recent the use of anti-radiation fibrosis drugs (pentoxifylline, tocopherol and clodronate)."4.91The management of osteoradionecrosis of the jaws--a review. ( Ekanayake, K; Omer, O; Polyzois, I; Rice, N; Stassen, LF, 2015)
"The aim of this experimental study was to investigate the prophylactic effect of pentoxifylline (PTX) on medication-related osteonecrosis of the jaw (MRONJ)."3.85Preventive Effect of Phosphodiesterase Inhibitor Pentoxifylline Against Medication-Related Osteonecrosis of the Jaw: An Animal Study. ( Cumbul, A; Duygu-Capar, G; Sencift, K; Uslu, Ü; Yalcin-Ulker, GM, 2017)
"Pentoxifylline has been used to treat complications related to fibrosis for over 20 years."2.55Pentoxifylline - a review of its use in osteoradionecrosis. ( Brennan, PA; Lyons, AJ, 2017)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's7 (87.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yalcin-Ulker, GM1
Cumbul, A1
Duygu-Capar, G1
Uslu, Ü1
Sencift, K1
Kolokythas, A1
Rasmussen, JT1
Reardon, J1
Feng, C1
McCaul, JA1
Rice, N1
Polyzois, I1
Ekanayake, K1
Omer, O1
Stassen, LF1
Lyons, AJ1
Brennan, PA2
Lyons, A1
Ghazali, N1
Epstein, MS1
Wicknick, FW1
Epstein, JB1
Berenson, JR1
Gorsky, M1
McLeod, NM1
Pratt, CA1
Mellor, TK1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pentoxifylline and Tocopherol (PENTO) in the Treatment of Medication-related Osteonecrosis of the Jaw (MRONJ): A Prospective, Randomized Controlled Trial to Evaluate a Novel Non-operative Treatment[NCT03040778]Phase 3100 participants (Anticipated)Interventional2018-04-01Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for pentoxifylline and Jaw Diseases

ArticleYear
Management of osteoradionecrosis of the jaws with pentoxifylline-tocopherol: a systematic review of the literature and meta-analysis.
    International journal of oral and maxillofacial surgery, 2019, Volume: 48, Issue:2

    Topics: Antioxidants; Drug Combinations; Head and Neck Neoplasms; Humans; Jaw Diseases; Osteoradionecrosis;

2019
Pharmacologic modalities in the treatment of osteoradionecrosis of the jaw.
    Oral and maxillofacial surgery clinics of North America, 2014, Volume: 26, Issue:2

    Topics: Anti-Bacterial Agents; Antioxidants; Bone Density Conservation Agents; Chemoradiotherapy; Clodronic

2014
The management of osteoradionecrosis of the jaws--a review.
    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, 2015, Volume: 13, Issue:2

    Topics: Algorithms; Anti-Inflammatory Agents; Clodronic Acid; Fibrosis; Head and Neck Neoplasms; Humans; Hyp

2015
Pentoxifylline - a review of its use in osteoradionecrosis.
    The British journal of oral & maxillofacial surgery, 2017, Volume: 55, Issue:3

    Topics: Humans; Jaw Diseases; Osteoradionecrosis; Pentoxifylline

2017

Other Studies

4 other studies available for pentoxifylline and Jaw Diseases

ArticleYear
Preventive Effect of Phosphodiesterase Inhibitor Pentoxifylline Against Medication-Related Osteonecrosis of the Jaw: An Animal Study.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2017, Volume: 75, Issue:11

    Topics: Animals; Female; Jaw Diseases; Osteonecrosis; Pentoxifylline; Phosphodiesterase Inhibitors; Rats, Sp

2017
Osteoradionecrosis of the jaws: current understanding of its pathophysiology and treatment.
    The British journal of oral & maxillofacial surgery, 2008, Volume: 46, Issue:8

    Topics: Animals; Antioxidants; Cranial Irradiation; Cytokines; Drug Combinations; Drug Synergism; Fibrosis;

2008
Management of bisphosphonate-associated osteonecrosis: pentoxifylline and tocopherol in addition to antimicrobial therapy. An initial case series.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2010, Volume: 110, Issue:5

    Topics: Administration, Oral; Aged; Aged, 80 and over; alpha-Tocopherol; Anti-Infective Agents, Local; Antio

2010
Pentoxifylline and tocopherol in the management of patients with osteoradionecrosis, the Portsmouth experience.
    The British journal of oral & maxillofacial surgery, 2012, Volume: 50, Issue:1

    Topics: Aged; Antioxidants; Female; Follow-Up Studies; Humans; Jaw Diseases; Male; Middle Aged; Mouth Neopla

2012