pentoxifylline has been researched along with Ischemia in 106 studies
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 114 patients with critical lower limb ischemia from 11 hospitals were randomized to either Pentoxifylline 600 mg or placebo given intravenously twice a day." | 9.08 | Efficacy and clinical tolerance of parenteral pentoxifylline in the treatment of critical lower limb ischemia. A placebo controlled multicenter study. Norwegian Pentoxifylline Multicenter Trial Group. ( , 1996) |
| "This study aimed to assess the clinical efficacy of pentoxifylline (PTX) and L-glutamine (L-Gln) treatment on ischemia and reperfusion (I/R) injury in the abomasal tissue, acute phase response (APR), oxidative stress (OS), cytokine response, hemostatic, and coagulation disorders in the 96-h period before and after surgery in displaced abomasum (DA) cases." | 8.02 | The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study. ( Arican, M; Çöl, R; Ider, M; Maden, M; Parlak, K; Tras, B; Yildiz, R, 2021) |
| "We studied the new anti-inflammatory effects of non-specific phosphodiesterase (PDE) inhibitor pentoxifylline (PTX) on ischaemia-reperfusion injury and postconditioning of the lower extremities." | 7.85 | Pentoxifylline attenuates the local and systemic inflammatory response after infrarenal abdominal aortic ischemia-reperfusion. ( Arató, E; Fazekas, G; Hardi, P; Jancsó, G; Nagy, T; Petrovics, L; Pintér, Ö; Sínay, L; Takács, I; Tóth, M, 2017) |
| "To investigate the action of pentoxifylline (PTX) and prostaglandin E1 (PGE1) on ischemia and reperfusion of small intestine tissue in rats, using immunohistochemical analysis." | 7.81 | Pentoxifylline and prostaglandin E1 action on ischemia and reperfusion of small intestine tissue in rats. An immunohistochemical study. ( Assis, PV; Aydos, RD; Brasileiro, JL; Marks, G; Ramalho, RT; Silva, IS; Takita, LC, 2015) |
| " Administration of pentoxifylline reduced the collagen density caused by ischemic priapism in groups 3, 4 and 5 compared with group 2." | 7.80 | The effect of pentoxifylline on penile cavernosal tissues in ischemic priapism-induced rat model. ( Atilgan, D; Erdemir, F; Firat, F; Gencten, Y; Kuyucu, YE; Markoc, F; Parlaktas, BS, 2014) |
| "To evaluate intestinal inflammatory and apoptotic processes after intestinal ischemia/reperfusion injury, modulated by pentoxifylline and hypertonic saline." | 7.80 | Pentoxifylline associated to hypertonic saline solution attenuates inflammatory process and apoptosis after intestinal ischemia/reperfusion in rats. ( Belon, AR; Carvalho, JG; Felice Neto, R; Marques, GM; Montero, EF; Rasslan, R; Rasslan, S; Utiyama, EM, 2014) |
| "To investigate whether pentoxifylline (PTX) could influence the increased cytokine gene expression in the retina flowing transient ischemia, and if so, whether it acts through the modulation of nuclear factor kappa B (NF-kappaB) activation." | 7.73 | Pentoxifylline decreases up-regulated nuclear factor kappa B activation and cytokine production in the rat retina following transient ischemia. ( Ji, Q; Jia, H; Lv, R; Xu, J; Zhang, L, 2006) |
| "This study was designed to clarify the effects of pentoxifylline (PTX) and N-acetylcysteine (NAC) on hepatic reperfusion injury in rats." | 7.70 | Pentoxifylline and N-acetylcysteine in hepatic ischemia/reperfusion injury. ( Demir, S; Inal-Erden, M, 1998) |
| "In an effort to determine whether treatment with lisofylline (LSF) ameliorates intestinal barrier dysfunction in rats subjected to mesenteric ischemia and reperfusion (I/R), regional mesenteric vessels were occluded for 60 min and then unclamped for 60 min more." | 7.70 | Lisofylline ameliorates intestinal mucosal barrier dysfunction caused by ischemia and ischemia/reperfusion. ( Delude, RL; Fink, MP; Menconi, MJ; Wattanasirichaigoon, S, 1999) |
| "We examined whether pentoxifylline (PTX) and coenzyme Q10 (Q) pretreatment affect ischemia-reperfusion damage in the rat liver." | 7.70 | Effects of pentoxifylline and coenzyme Q10 in hepatic ischemia/reperfusion injury. ( Inal-Erden, M; Portakal, O, 1999) |
| "This study indicates that intraoperative, intravenous pentoxifylline reduces hepatic injury after warm ischemia and reperfusion." | 7.69 | Effect of pentoxifylline on hepatic ischemia and reperfusion injury. ( Fabia, R; Goldstein, RM; Husberg, BS; Klintmalm, GB; Levy, MF; Travis, DL, 1997) |
| "The effect of pretreatment with pentoxifylline on normothermic liver ischemia was studied in rats." | 7.69 | [Liver damage due to normothermic ischemia and reperfusion in the rat. The effects of pentoxifylline pretreatment]. ( Castillo Olivares Ramos, JL; Martínez Onturbe, P; Navidad Novalvos, R; Ratia Giménez, T; Santamaría Solís, LV, 1995) |
| "Pentoxifylline reduces alveolar capillary membrane injury and subsequent protein leakage and improves cardiac output when administered after 30 minutes of intestinal ischemia." | 7.69 | Pentoxifylline attenuates pulmonary macromolecular leakage after intestinal ischemia-reperfusion. ( Carter, MB; Garrison, RN; Wead, WB; Wilson, MA, 1995) |
| "In vivo videomicroscopy was used to quantitate alterations of the small-intestine microcirculation during Escherichia coli bacteremia in rats pretreated with either intravenous pentoxifylline or saline solution." | 7.68 | Pentoxifylline preserves small-intestine microvascular blood flow during bacteremia. ( Garrison, RN; Steeb, GD; Wilson, MA, 1992) |
| "Twenty patients with ischemic rest pain were treated with intravenous pentoxifylline, 1,200 mg daily, for up to three weeks." | 7.67 | Intravenous pentoxifylline in the treatment of rest pain: a preliminary report. ( Carey, D; Kent, P; McCollum, PT; Moore, DJ; O'Driscoll, K; Shanik, DG; Stanley, ST; Weil von der Ahe, CA, 1989) |
| "Pentoxifylline (PTX) has been shown to suppress TNF alpha (released by activated macrophages, inhibiting subsequent superoxide anion release from neutrophil activation." | 6.68 | A randomized controlled trial of pentoxifylline for the prevention of delayed graft function in cadaveric kidney graft. ( Codaccioni, MX; Coppin, MC; Hazzan, M; Labalette, M; Lelièvre, G; Noël, C; Pruvot, FR, 1997) |
| "Pentoxifylline is a methylxanthine compound which was first filed in 1973 and registered in 1974 in the United States by Sanofi-Aventis Deustchland Gmbh for the treatment of intermittent claudication for chronic occlusive arterial disease." | 6.50 | Pentoxifylline in liver ischemia and reperfusion. ( Cejalvo, D; García, D; Genovés, P; Lloris-Carsi, JM; Martin, A; Toledo, AH; Toledo-Pereyra, LH; Zaragoza, C, 2014) |
| "Glans ischemia is an extremely infrequent complication characterized by a total or partial compromise in the penile arterial perfusion." | 5.91 | Glans Penis Ischemia after Circumcision in a 15-Year-Old Patient Managed with Intravenous Pentoxifylline: A Case Report and a Diagnostic-Therapeutic Guideline Proposal. ( Antona, G; Arredondo Montero, J; Bardají Pascual, C; Bronte Anaut, M; Ros Briones, R, 2023) |
| "Ischemia is an important cause of acute kidney injury (AKI)." | 5.35 | Pentoxifylline in ischemia-induced acute kidney injury in rats. ( Martinelli, R; Okumura, AS; Rodrigues, LE, 2009) |
| "Ischaemia/reperfusion injury was produced by hepatic pedicle clamping, as demonstrated by AST, ALT and LDH increase." | 5.31 | Allopurinol plus pentoxifilline in hepatic ischaemia/reperfusion injury. ( Baykan, A; Erdem, L; Köksal, H; Tok, H; Yildirim, S, 2002) |
| "To clarify the effects of PTXF in reperfusion injury, we measured the resting transmembrane potential difference (Em) and evaluated postcapillary venule microcirculation using intravital microscopy in rat skeletal muscle during ischemia and reperfusion." | 5.30 | Pentoxifylline attenuates reperfusion injury in skeletal muscle after partial ischemia. ( Kishi, M; Matsuoka, T; Seiyama, A; Sugimoto, H; Takaoka, M; Tanaka, H; Yoshioka, T, 1998) |
| "This study aimed to assess the clinical efficacy of pentoxifylline (PTX) and L-glutamine (L-Gln) treatment on ischemia and reperfusion (I/R) injury in the abomasal tissue, acute phase response (APR), oxidative stress (OS), cytokine response, hemostatic, and coagulation disorders in the 96-h period before and after surgery in displaced abomasum (DA) cases." | 4.02 | The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study. ( Arican, M; Çöl, R; Ider, M; Maden, M; Parlak, K; Tras, B; Yildiz, R, 2021) |
| "We studied the new anti-inflammatory effects of non-specific phosphodiesterase (PDE) inhibitor pentoxifylline (PTX) on ischaemia-reperfusion injury and postconditioning of the lower extremities." | 3.85 | Pentoxifylline attenuates the local and systemic inflammatory response after infrarenal abdominal aortic ischemia-reperfusion. ( Arató, E; Fazekas, G; Hardi, P; Jancsó, G; Nagy, T; Petrovics, L; Pintér, Ö; Sínay, L; Takács, I; Tóth, M, 2017) |
| "To investigate the action of pentoxifylline (PTX) and prostaglandin E1 (PGE1) on ischemia and reperfusion of small intestine tissue in rats, using immunohistochemical analysis." | 3.81 | Pentoxifylline and prostaglandin E1 action on ischemia and reperfusion of small intestine tissue in rats. An immunohistochemical study. ( Assis, PV; Aydos, RD; Brasileiro, JL; Marks, G; Ramalho, RT; Silva, IS; Takita, LC, 2015) |
| " Administration of pentoxifylline reduced the collagen density caused by ischemic priapism in groups 3, 4 and 5 compared with group 2." | 3.80 | The effect of pentoxifylline on penile cavernosal tissues in ischemic priapism-induced rat model. ( Atilgan, D; Erdemir, F; Firat, F; Gencten, Y; Kuyucu, YE; Markoc, F; Parlaktas, BS, 2014) |
| "To evaluate intestinal inflammatory and apoptotic processes after intestinal ischemia/reperfusion injury, modulated by pentoxifylline and hypertonic saline." | 3.80 | Pentoxifylline associated to hypertonic saline solution attenuates inflammatory process and apoptosis after intestinal ischemia/reperfusion in rats. ( Belon, AR; Carvalho, JG; Felice Neto, R; Marques, GM; Montero, EF; Rasslan, R; Rasslan, S; Utiyama, EM, 2014) |
| "Cilostazol at a dose of 30 mg/kg twice a day promoted improvement in gait performance in rats submitted to chronic hindlimb ischemia." | 3.78 | Effect of cilostazol and pentoxifylline on gait biomechanics in rats with ischemic left hindlimb. ( Bredarioli, M; Dalio, MB; do Prado, WA; Joviliano, EE; Piccinato, CE, 2012) |
| "To investigate whether pentoxifylline (PTX) could influence the increased cytokine gene expression in the retina flowing transient ischemia, and if so, whether it acts through the modulation of nuclear factor kappa B (NF-kappaB) activation." | 3.73 | Pentoxifylline decreases up-regulated nuclear factor kappa B activation and cytokine production in the rat retina following transient ischemia. ( Ji, Q; Jia, H; Lv, R; Xu, J; Zhang, L, 2006) |
| "This study was designed to clarify the effects of pentoxifylline (PTX) and N-acetylcysteine (NAC) on hepatic reperfusion injury in rats." | 3.70 | Pentoxifylline and N-acetylcysteine in hepatic ischemia/reperfusion injury. ( Demir, S; Inal-Erden, M, 1998) |
| "In an effort to determine whether treatment with lisofylline (LSF) ameliorates intestinal barrier dysfunction in rats subjected to mesenteric ischemia and reperfusion (I/R), regional mesenteric vessels were occluded for 60 min and then unclamped for 60 min more." | 3.70 | Lisofylline ameliorates intestinal mucosal barrier dysfunction caused by ischemia and ischemia/reperfusion. ( Delude, RL; Fink, MP; Menconi, MJ; Wattanasirichaigoon, S, 1999) |
| "We examined whether pentoxifylline (PTX) and coenzyme Q10 (Q) pretreatment affect ischemia-reperfusion damage in the rat liver." | 3.70 | Effects of pentoxifylline and coenzyme Q10 in hepatic ischemia/reperfusion injury. ( Inal-Erden, M; Portakal, O, 1999) |
| "Pentoxifylline reduces alveolar capillary membrane injury and subsequent protein leakage and improves cardiac output when administered after 30 minutes of intestinal ischemia." | 3.69 | Pentoxifylline attenuates pulmonary macromolecular leakage after intestinal ischemia-reperfusion. ( Carter, MB; Garrison, RN; Wead, WB; Wilson, MA, 1995) |
| "The effect of pretreatment with pentoxifylline on normothermic liver ischemia was studied in rats." | 3.69 | [Liver damage due to normothermic ischemia and reperfusion in the rat. The effects of pentoxifylline pretreatment]. ( Castillo Olivares Ramos, JL; Martínez Onturbe, P; Navidad Novalvos, R; Ratia Giménez, T; Santamaría Solís, LV, 1995) |
| "This study examines the hypothesis that pentoxifylline protects renal PGE2 synthesis during mesenteric ischemia/reperfusion injury." | 3.69 | Acute mesenteric ischemia/reperfusion down regulates renal PGE2 synthesis. ( Hernandez, RH; Horton, JW; Myers, SI, 1995) |
| "This study indicates that intraoperative, intravenous pentoxifylline reduces hepatic injury after warm ischemia and reperfusion." | 3.69 | Effect of pentoxifylline on hepatic ischemia and reperfusion injury. ( Fabia, R; Goldstein, RM; Husberg, BS; Klintmalm, GB; Levy, MF; Travis, DL, 1997) |
| "In vivo videomicroscopy was used to quantitate alterations of the small-intestine microcirculation during Escherichia coli bacteremia in rats pretreated with either intravenous pentoxifylline or saline solution." | 3.68 | Pentoxifylline preserves small-intestine microvascular blood flow during bacteremia. ( Garrison, RN; Steeb, GD; Wilson, MA, 1992) |
| "Twenty patients with ischemic rest pain were treated with intravenous pentoxifylline, 1,200 mg daily, for up to three weeks." | 3.67 | Intravenous pentoxifylline in the treatment of rest pain: a preliminary report. ( Carey, D; Kent, P; McCollum, PT; Moore, DJ; O'Driscoll, K; Shanik, DG; Stanley, ST; Weil von der Ahe, CA, 1989) |
| "The effect of pentoxifylline on the recovery of renal energy metabolism after ischemia and reperfusion was studied by 31P nuclear magnetic resonance spectroscopy in vivo." | 3.67 | Effect of pentoxifylline on the ischemic rat kidney monitored by 31P NMR spectroscopy in vivo. ( Ellermann, J; Gründer, W; Keller, T, 1988) |
| "Pentoxifylline (PTX) has been shown to suppress TNF alpha (released by activated macrophages, inhibiting subsequent superoxide anion release from neutrophil activation." | 2.68 | A randomized controlled trial of pentoxifylline for the prevention of delayed graft function in cadaveric kidney graft. ( Codaccioni, MX; Coppin, MC; Hazzan, M; Labalette, M; Lelièvre, G; Noël, C; Pruvot, FR, 1997) |
| "Pentoxifylline is a methylxanthine compound which was first filed in 1973 and registered in 1974 in the United States by Sanofi-Aventis Deustchland Gmbh for the treatment of intermittent claudication for chronic occlusive arterial disease." | 2.50 | Pentoxifylline in liver ischemia and reperfusion. ( Cejalvo, D; García, D; Genovés, P; Lloris-Carsi, JM; Martin, A; Toledo, AH; Toledo-Pereyra, LH; Zaragoza, C, 2014) |
| "Colonic ischemia was established in all the groups." | 1.37 | Effect of pentoxifylline and vinpocetine on the healing of ischemic colon anastomosis: an experimental study. ( Altınlı, E; Eroğlu, E; Güneş, P; Köksal, N; Onur, E; Senger, S; Sümer, A, 2011) |
| "Ischemia is an important cause of acute kidney injury (AKI)." | 1.35 | Pentoxifylline in ischemia-induced acute kidney injury in rats. ( Martinelli, R; Okumura, AS; Rodrigues, LE, 2009) |
| "Ischaemia/reperfusion injury was produced by hepatic pedicle clamping, as demonstrated by AST, ALT and LDH increase." | 1.31 | Allopurinol plus pentoxifilline in hepatic ischaemia/reperfusion injury. ( Baykan, A; Erdem, L; Köksal, H; Tok, H; Yildirim, S, 2002) |
| "To clarify the effects of PTXF in reperfusion injury, we measured the resting transmembrane potential difference (Em) and evaluated postcapillary venule microcirculation using intravital microscopy in rat skeletal muscle during ischemia and reperfusion." | 1.30 | Pentoxifylline attenuates reperfusion injury in skeletal muscle after partial ischemia. ( Kishi, M; Matsuoka, T; Seiyama, A; Sugimoto, H; Takaoka, M; Tanaka, H; Yoshioka, T, 1998) |
| "Torbafylline treatment had little further effect on ischemic muscles subjected to mild stimulation, which on its own improved functional hyperemia, resistance to fatigue, and the capillaries per fibre ratio in tibialis anterior, although it did significantly increase the capillary per fibre ratio in extensor digitorum longus." | 1.29 | Effect of torbafylline on muscle blood flow, performance, and capillary supply in ischemic muscles subjected to varying levels of activity. ( Brown, MD; Egginton, S; Hudlicka, O; Okyayuz-Baklouti, I, 1994) |
| "Torbafylline or water was given by gavage morning and evening." | 1.29 | Fine structure of capillaries in ischaemic and non ischaemic rat striated muscle. Effect of torbafylline. ( Egginton, S; Glover, M; Hudlicka, O, 1993) |
| "3." | 1.28 | The effect of torbafylline on enzyme activities in fast and slow muscles with limited blood supply. ( Egginton, S; Hudlická, O, 1991) |
| " In order to obtain information on oxygen supply, energy metabolism and function of ischaemic calf muscle in rats and cats, muscle pO2, pH and contractility were measured before and after dosing of BRL 30892." | 1.27 | The effect of 7-(2'-oxopropyl)-1,3-di-n-butyl-xanthine (BRL 30892) on ischaemic skeletal muscle pO2, pH and contractility in cats and rats. ( Angersbach, D; Ochlich, P, 1984) |
| " Consequently, when a dialysis patient required this drug, we started at a low dose and gradually increased the dosage while monitoring the patient for signs or symptoms of toxicity and following plasma concentrations of parent drug and its metabolites." | 1.27 | Pentoxifylline in end-stage renal disease. ( Kroboth, PD; Silver, MR, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (19.81) | 18.7374 |
| 1990's | 44 (41.51) | 18.2507 |
| 2000's | 23 (21.70) | 29.6817 |
| 2010's | 15 (14.15) | 24.3611 |
| 2020's | 3 (2.83) | 2.80 |
| Authors | Studies |
|---|---|
| Maden, M | 1 |
| Yildiz, R | 1 |
| Çöl, R | 1 |
| Arican, M | 1 |
| Ider, M | 1 |
| Parlak, K | 1 |
| Tras, B | 1 |
| Arredondo Montero, J | 2 |
| Antona, G | 2 |
| Ros Briones, R | 2 |
| Bronte Anaut, M | 2 |
| Bardají Pascual, C | 2 |
| Carlaw, K | 1 |
| Chia, D | 1 |
| Allaway, M | 1 |
| Harvey, J | 1 |
| Vietto, V | 1 |
| Franco, JV | 1 |
| Saenz, V | 1 |
| Cytryn, D | 1 |
| Chas, J | 1 |
| Ciapponi, A | 1 |
| Eğin, S | 1 |
| İlhan, M | 1 |
| Bademler, S | 1 |
| Gökçek, B | 1 |
| Hot, S | 1 |
| Ekmekçi, H | 1 |
| Ekmekçi, ÖB | 1 |
| Tanrıverdi, G | 1 |
| Dağıstanlı, FK | 1 |
| Kamalı, G | 1 |
| Kamalı, S | 1 |
| Güloğlu, R | 1 |
| Ragavendran, JV | 1 |
| Laferrière, A | 1 |
| Khorashadi, M | 1 |
| Coderre, TJ | 1 |
| Genovés, P | 1 |
| García, D | 1 |
| Cejalvo, D | 1 |
| Martin, A | 1 |
| Zaragoza, C | 1 |
| Toledo, AH | 1 |
| Toledo-Pereyra, LH | 1 |
| Lloris-Carsi, JM | 1 |
| Brasileiro, JL | 2 |
| Inoye, CM | 1 |
| Aydos, RD | 2 |
| Silva, IS | 2 |
| Falcão, GR | 1 |
| Marks, G | 2 |
| Pereira, DM | 1 |
| Erdemir, F | 1 |
| Firat, F | 1 |
| Markoc, F | 1 |
| Atilgan, D | 1 |
| Parlaktas, BS | 1 |
| Kuyucu, YE | 1 |
| Gencten, Y | 1 |
| Marques, GM | 1 |
| Rasslan, R | 1 |
| Belon, AR | 1 |
| Carvalho, JG | 1 |
| Felice Neto, R | 1 |
| Rasslan, S | 1 |
| Utiyama, EM | 1 |
| Montero, EF | 1 |
| Ramalho, RT | 1 |
| Takita, LC | 1 |
| Assis, PV | 1 |
| Rocha-Santos, V | 1 |
| Figueira, ER | 1 |
| Rocha-Filho, JA | 1 |
| Coelho, AM | 1 |
| Pinheiro, RS | 1 |
| Bacchella, T | 1 |
| Machado, MC | 1 |
| D'Albuquerque, LA | 1 |
| Migliorini, F | 1 |
| Bianconi, F | 1 |
| Bizzotto, L | 1 |
| Porcaro, AB | 1 |
| Artibani, W | 1 |
| Fichter, AM | 1 |
| Ritschl, LM | 1 |
| Robitzky, LK | 1 |
| Wagenpfeil, S | 1 |
| Mitchell, DA | 1 |
| Wolff, KD | 1 |
| Mücke, T | 1 |
| Nagy, T | 1 |
| Hardi, P | 1 |
| Takács, I | 1 |
| Tóth, M | 1 |
| Petrovics, L | 1 |
| Jancsó, G | 1 |
| Sínay, L | 1 |
| Fazekas, G | 1 |
| Pintér, Ö | 1 |
| Arató, E | 1 |
| Wystrychowski, A | 1 |
| Wystrychowski, W | 1 |
| Król, P | 1 |
| Obuchowicz, E | 1 |
| Cierpka, L | 1 |
| Wiecek, A | 1 |
| Okumura, AS | 1 |
| Rodrigues, LE | 1 |
| Martinelli, R | 1 |
| Elemen, L | 1 |
| Topçu, K | 1 |
| Gürcan, Nİ | 1 |
| Akay, A | 1 |
| Sümer, A | 1 |
| Altınlı, E | 1 |
| Senger, S | 1 |
| Köksal, N | 1 |
| Onur, E | 1 |
| Eroğlu, E | 1 |
| Güneş, P | 1 |
| Bredarioli, M | 1 |
| Dalio, MB | 1 |
| Joviliano, EE | 1 |
| do Prado, WA | 1 |
| Piccinato, CE | 1 |
| Yildirim, S | 1 |
| Tok, H | 1 |
| Köksal, H | 1 |
| Erdem, L | 1 |
| Baykan, A | 1 |
| Arnault, I | 1 |
| Bao, YM | 1 |
| Sebagh, M | 1 |
| Anjo, A | 1 |
| Dimicoli, JL | 1 |
| Lemoine, A | 1 |
| Delvart, V | 1 |
| Adam, R | 1 |
| Selzner, N | 1 |
| Rudiger, H | 1 |
| Graf, R | 1 |
| Clavien, PA | 2 |
| Tzeng, YS | 1 |
| Tang, SH | 1 |
| Meng, E | 1 |
| Lin, TF | 1 |
| Sun, GH | 1 |
| Drozdz, W | 1 |
| Kedryna, T | 1 |
| Ostrowska, B | 1 |
| Wilczek, M | 1 |
| Stachurska, B | 1 |
| Alekhin, DI | 1 |
| Fokin, AN | 1 |
| Galenko-Yaroshevskii, PA | 1 |
| Alukhanyan, OA | 1 |
| Kurganskii, OV | 1 |
| Fedchenko, YY | 1 |
| Agarwal, P | 1 |
| Agrawal, PK | 1 |
| Sharma, D | 1 |
| Baghel, KD | 1 |
| Uguralp, S | 1 |
| Bay Karabulut, A | 1 |
| Mizrak, B | 1 |
| Hödl, S | 1 |
| Gorelasvili, A | 1 |
| Antelava, N | 1 |
| Aslan, A | 1 |
| Karagüzel, G | 1 |
| Melikoglu, M | 1 |
| Di Salvo, MM | 1 |
| Ardita, G | 1 |
| Giani, L | 1 |
| Mugno, F | 1 |
| Stevenazzi, F | 1 |
| Mazzone, A | 1 |
| Ji, Q | 1 |
| Zhang, L | 1 |
| Lv, R | 1 |
| Jia, H | 1 |
| Xu, J | 1 |
| Parra-Membrives, P | 1 |
| Ruiz-Luque, V | 1 |
| Escudero-Severín, C | 1 |
| Aguilar-Luque, J | 1 |
| Méndez-García, V | 1 |
| Ertem, K | 1 |
| Ermolaev, VL | 2 |
| Burleva, EP | 1 |
| Angersbach, D | 1 |
| Ochlich, P | 1 |
| Kirpatovskiĭ, VI | 2 |
| Onishchenko, NA | 1 |
| Lubiako, AA | 1 |
| Danilov, MA | 1 |
| Bogoiavlenskaia, TA | 1 |
| Ruberti, U | 1 |
| Morbidelli, A | 1 |
| Kaz'min, AI | 1 |
| Pavlova, GA | 1 |
| Travkin, AA | 1 |
| Mitskevich, VA | 1 |
| Naess, K | 1 |
| Carter, MB | 1 |
| Wilson, MA | 2 |
| Wead, WB | 1 |
| Garrison, RN | 2 |
| Makarova, NP | 1 |
| Zavalskiĭ, II | 1 |
| Ratia Giménez, T | 1 |
| Navidad Novalvos, R | 1 |
| Martínez Onturbe, P | 1 |
| Santamaría Solís, LV | 1 |
| Castillo Olivares Ramos, JL | 1 |
| Normandin, L | 1 |
| Hervé, P | 2 |
| Brink, C | 1 |
| Chapelier, AR | 1 |
| Dartevelle, PG | 1 |
| Mazmanian, GM | 1 |
| Myers, SI | 2 |
| Hernandez, RH | 1 |
| Horton, JW | 2 |
| Sakio, H | 1 |
| Tanaka, Y | 1 |
| Ueno, K | 1 |
| Oishi, S | 1 |
| Ohtsu, S | 1 |
| Okuda, C | 1 |
| Puchmayer, V | 1 |
| Hudlicka, O | 4 |
| Egginton, S | 3 |
| Brown, MD | 1 |
| Okyayuz-Baklouti, I | 4 |
| Ciuffetti, G | 1 |
| Paltriccia, R | 1 |
| Lombardini, R | 1 |
| Lupattelli, G | 1 |
| Pasqualini, L | 1 |
| Mannarino, E | 1 |
| Skjeldal, S | 1 |
| Hvaal, K | 1 |
| Nordsletten, L | 1 |
| Aasen, AO | 1 |
| Reikerås, O | 1 |
| Torvik, A | 1 |
| Takaro, TK | 1 |
| Coodley, GO | 1 |
| Hanazawa, S | 1 |
| Prewitt, RL | 1 |
| Terzis, JK | 1 |
| White, DJ | 1 |
| Glover, M | 1 |
| Koch, H | 1 |
| Norris, D | 1 |
| Kogler, H | 1 |
| Leibfritz, D | 1 |
| Hou, X | 1 |
| Baudry, N | 1 |
| Lenoble, M | 1 |
| Vicaut, E | 1 |
| Chapelier, A | 1 |
| Reignier, J | 1 |
| Mazmanian, M | 1 |
| Detruit, H | 1 |
| Dartevelle, P | 1 |
| Parquin, F | 1 |
| Cerrina, J | 1 |
| Le Roy Ladurie, F | 1 |
| Colgan, MP | 1 |
| Moore, DJ | 2 |
| Shanik, GD | 1 |
| Ates, E | 1 |
| Sharma, P | 1 |
| Erkasap, S | 1 |
| Talbot, D | 1 |
| Ihtiyar, E | 1 |
| Yasar, B | 1 |
| Kiper, H | 1 |
| Vadiei, K | 1 |
| Tucker, SD | 1 |
| Lopez-Berestein, G | 1 |
| Wasan, KM | 1 |
| Coe, DA | 1 |
| Freischlag, JA | 1 |
| Johnson, D | 1 |
| Mudaliar, JH | 1 |
| Kosciesza, SA | 1 |
| Traul, DK | 1 |
| Chiang, PC | 1 |
| Cambria, RA | 1 |
| Seabrook, GR | 1 |
| Towne, JB | 1 |
| Fabia, R | 1 |
| Travis, DL | 1 |
| Levy, MF | 1 |
| Husberg, BS | 1 |
| Goldstein, RM | 1 |
| Klintmalm, GB | 1 |
| Noël, C | 1 |
| Hazzan, M | 1 |
| Coppin, MC | 1 |
| Codaccioni, MX | 1 |
| Pruvot, FR | 1 |
| Labalette, M | 1 |
| Lelièvre, G | 1 |
| Rothenbach, P | 1 |
| Turnage, RH | 1 |
| Iglesias, J | 1 |
| Riva, A | 1 |
| Bartula, L | 1 |
| Santiago-Delpín, EA | 1 |
| Lamm, K | 3 |
| Lamm, C | 1 |
| Arnold, W | 2 |
| Kishi, M | 1 |
| Tanaka, H | 1 |
| Seiyama, A | 1 |
| Takaoka, M | 1 |
| Matsuoka, T | 1 |
| Yoshioka, T | 1 |
| Sugimoto, H | 1 |
| McNamara, DB | 1 |
| Champion, HC | 1 |
| Kadowitz, PJ | 1 |
| Demir, S | 1 |
| Inal-Erden, M | 2 |
| Wattanasirichaigoon, S | 1 |
| Menconi, MJ | 1 |
| Delude, RL | 1 |
| Fink, MP | 1 |
| Kazachenko, AV | 1 |
| Ianenko, EK | 1 |
| Kovalenko, EA | 1 |
| Golovanov, SA | 1 |
| Mahler, V | 1 |
| Neureiter, D | 1 |
| Kirchner, T | 1 |
| Schuler, G | 1 |
| Fartasch, M | 1 |
| Portakal, O | 1 |
| Doi, H | 1 |
| Kaburaki, M | 1 |
| Inoue, H | 1 |
| Suzumura, K | 1 |
| Narita, H | 1 |
| Rüdiger, HA | 1 |
| Karimov, ZZ | 1 |
| Bakhritdinov, FSh | 1 |
| Trynkin, AV | 1 |
| Hartmann, JF | 1 |
| Becker, RA | 1 |
| Cohen, MM | 1 |
| Gerzić, Z | 1 |
| Dukić, V | 1 |
| Milicević, M | 1 |
| Steeb, GD | 1 |
| Elliot, EC | 1 |
| Kollarits, CR | 1 |
| Ernst, E | 1 |
| Ellermann, J | 2 |
| David, H | 1 |
| Lüning, M | 1 |
| Gewiese, B | 1 |
| Stiller, D | 1 |
| Römer, T | 1 |
| Plötz, M | 1 |
| Wolf, KJ | 1 |
| Dawson, JM | 1 |
| Weselcouch, EO | 1 |
| Demusz, CD | 1 |
| Dinn, RF | 1 |
| Yang, HT | 1 |
| Terjung, RL | 1 |
| Galvin, KT | 1 |
| Gorst, KL | 1 |
| Primrose, JN | 1 |
| Kester, RC | 1 |
| Beykirch, H | 1 |
| Reuter, W | 1 |
| Voigt, H | 1 |
| Herrmann, W | 1 |
| Tikhonov, VP | 1 |
| Statsenko, ME | 1 |
| McCollum, PT | 1 |
| Kent, P | 1 |
| O'Driscoll, K | 1 |
| Carey, D | 1 |
| Stanley, ST | 1 |
| Weil von der Ahe, CA | 1 |
| Shanik, DG | 1 |
| Gründer, W | 1 |
| Keller, T | 1 |
| Barker, JH | 1 |
| Menger, MD | 1 |
| Sack, FU | 1 |
| Messmer, K | 1 |
| Basistiuk, II | 1 |
| Silver, MR | 1 |
| Kroboth, PD | 1 |
| Grossmann, K | 1 |
| Knischka, A | 1 |
| Mavrelis, PG | 1 |
| Doumanian, H | 1 |
| Utiamyshev, RI | 1 |
| Aref'ev, IM | 1 |
| Mazovetskiĭ, AG | 1 |
| Shevchenko, RA | 1 |
| Lee, BY | 1 |
| Berkowitz, P | 1 |
| Savitsky, JP | 1 |
| May, GS | 1 |
| Brobst, J | 1 |
| McCann, WJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of N-acetylcysteine on Preservation Solution During Liver Transplantation[NCT01866644] | Phase 3 | 214 participants (Actual) | Interventional | 2011-09-30 | Completed | ||
| The Effect of Remote Ischemic Preconditioning on the Postoperative Liver Function in Living Donor Hepatectomy: a Randomized Clinical Trial[NCT03386435] | 160 participants (Actual) | Interventional | 2016-08-22 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The incidence of delayed recovery of hepatic function (DRHF) were used as surrogate parameters indicating the possible benefits of RIPC. DRHF was defined based on a proposal by the International Study Group of Liver Surgery, as follows: an impaired ability of the liver to maintain its synthetic, excretory, and detoxifying functions, which are characterized by an increased PT INR and concomitant hyperbilirubinemia (considering the normal limits of the local laboratory) on or after postoperative day 5. The normal upper limits of PT and bilirubin in our institutional laboratory were 1.30 INR and 1.2 mg/dL, respectively. If either the PT INR or serum bilirubin concentration was preoperatively elevated, DRHF was defined by an increasing PT INR and increasing serum bilirubin concentration on or after postoperative day 5 (compared with the values of the previous day). (NCT03386435)
Timeframe: postoperative 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| RIPC | 5 |
| Control | 0 |
The serial assessments of routine laboratory values were used as early markers for postoperative liver function. The maximal aspartate aminotransferase level within 7 postoperative days were assessed following RIPC in living donor hepatectomy. (NCT03386435)
Timeframe: within 7 days after operation
| Intervention | IU/L (Mean) |
|---|---|
| RIPC | 145 |
| Control | 152 |
The postoperative liver regeneration index (LRI) at postoperative 1 month ) was used as surrogate parameters indicating the possible benefits of RIPC. The LRI was defined as [(VLR - VFLR)/VFLR)] × 100, where VLR is the volume of the liver remnant and VFLR is the volume of the future liver remnant. Liver volume was calculated by CT volumetry using 3-mm-thick dynamic CT images. The graft weight was subtracted from the total liver volume to define the future liver remnant. (NCT03386435)
Timeframe: 1 month
| Intervention | percentage of liver volume (Mean) |
|---|---|
| RIPC | 83.3 |
| Control | 94.9 |
The serial assessments of routine laboratory values were used as early markers for postoperative liver function. The maximal alanine aminotransferase level within 7 postoperative days were assessed following RIPC in living donor hepatectomy (NCT03386435)
Timeframe: within 7 days after operation
| Intervention | IU/L (Mean) |
|---|---|
| RIPC | 148 |
| Control | 152 |
7 reviews available for pentoxifylline and Ischemia
| Article | Year |
|---|---|
Prostanoids for critical limb ischaemia.
Topics: Alprostadil; Amputation, Surgical; Epoprostenol; Humans; Iloprost; Ischemia; Leg; Leg Ulcer; Nafrony | 2018 |
Pentoxifylline in liver ischemia and reperfusion.
Topics: Animals; Apoptosis; Humans; Ischemia; Liver; Liver Diseases; Liver Transplantation; Pentoxifylline; | 2014 |
Acute Ischemia of the Glans Penis after Circumcision Treated with Hyperbaric Therapy and Pentoxifylline: Case Report and Revision of the Literature.
Topics: Adult; Anesthesia, Local; Bandages; Circumcision, Male; Humans; Hyperbaric Oxygenation; Ischemia; Ma | 2018 |
Protective strategies against ischemic injury of the liver.
Topics: Animals; Antioxidants; Genetic Therapy; Humans; Ischemia; Ischemic Preconditioning; Liver; Organ Pre | 2003 |
Protective strategies against ischemic injury of the liver.
Topics: Animals; Antioxidants; Genetic Therapy; Humans; Ischemia; Ischemic Preconditioning; Liver; Organ Pre | 2003 |
Protective strategies against ischemic injury of the liver.
Topics: Animals; Antioxidants; Genetic Therapy; Humans; Ischemia; Ischemic Preconditioning; Liver; Organ Pre | 2003 |
Protective strategies against ischemic injury of the liver.
Topics: Animals; Antioxidants; Genetic Therapy; Humans; Ischemia; Ischemic Preconditioning; Liver; Organ Pre | 2003 |
[Modern therapeutic trends in the conservative treatment of ischemic disease of the lower extremities].
Topics: Humans; Ischemia; Leg; Pentoxifylline | 1995 |
Pentoxifylline and critical leg ischemia.
Topics: Humans; Ischemia; Leg; Pentoxifylline; Regional Blood Flow; Vasodilator Agents | 1995 |
Pharmacologic management of peripheral vascular disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Arterial Occlusive Diseases; Cardiovascular Agents; Cycloo | 1998 |
5 trials available for pentoxifylline and Ischemia
| Article | Year |
|---|---|
Energostim in therapy of chronic ischemia of the lower limbs.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Coronary Disease; Cytochromes c; Drug Combinations | 2004 |
Intravenous pentoxifylline for the treatment of chronic critical limb ischaemia. The European Study Group.
Topics: Aged; Analgesics; Chronic Disease; Double-Blind Method; Female; Humans; Infusions, Intravenous; Isch | 1995 |
Efficacy and clinical tolerance of parenteral pentoxifylline in the treatment of critical lower limb ischemia. A placebo controlled multicenter study. Norwegian Pentoxifylline Multicenter Trial Group.
Topics: Aged; Double-Blind Method; Female; Humans; Infusions, Intravenous; Ischemia; Leg; Male; Pain Measure | 1996 |
A randomized controlled trial of pentoxifylline for the prevention of delayed graft function in cadaveric kidney graft.
Topics: Adult; Cadaver; Cyclosporine; Double-Blind Method; Endothelium, Vascular; Female; Humans; Immunosupp | 1997 |
Intravenous oxypentifylline in critical limb ischaemia.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesia; Arterial Occlusive Diseases; Blood | 1989 |
94 other studies available for pentoxifylline and Ischemia
| Article | Year |
|---|---|
The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study.
Topics: Abomasum; Animals; Cattle; Cattle Diseases; Female; Glutamine; Ischemia; Longitudinal Studies; Pento | 2021 |
Glans Penis Ischemia after Circumcision in a 15-Year-Old Patient Managed with Intravenous Pentoxifylline: A Case Report and a Diagnostic-Therapeutic Guideline Proposal.
Topics: Adolescent; Circumcision, Male; Humans; Ischemia; Male; Penis; Pentoxifylline | 2023 |
Glans Penis Ischemia after Circumcision in a 15-Year-Old Patient Managed with Intravenous Pentoxifylline: A Case Report and a Diagnostic-Therapeutic Guideline Proposal.
Topics: Adolescent; Circumcision, Male; Humans; Ischemia; Male; Penis; Pentoxifylline | 2023 |
Glans Penis Ischemia after Circumcision in a 15-Year-Old Patient Managed with Intravenous Pentoxifylline: A Case Report and a Diagnostic-Therapeutic Guideline Proposal.
Topics: Adolescent; Circumcision, Male; Humans; Ischemia; Male; Penis; Pentoxifylline | 2023 |
Glans Penis Ischemia after Circumcision in a 15-Year-Old Patient Managed with Intravenous Pentoxifylline: A Case Report and a Diagnostic-Therapeutic Guideline Proposal.
Topics: Adolescent; Circumcision, Male; Humans; Ischemia; Male; Penis; Pentoxifylline | 2023 |
Acute ischaemia of the glans penis post-circumcision managed with pentoxifylline, topical nitroglycerin and epidural.
Topics: Adolescent; Circumcision, Male; Humans; Ischemia; Male; Nitroglycerin; Penis; Pentoxifylline | 2023 |
Protective effects of pentoxifylline in small intestine after ischemia-reperfusion.
Topics: Animals; Cardiovascular Agents; Disease Models, Animal; Hematologic Agents; Infusions, Parenteral; I | 2018 |
Pentoxifylline reduces chronic post-ischaemia pain by alleviating microvascular dysfunction.
Topics: Animals; Disease Models, Animal; Ischemia; Male; Microvessels; Pain; Pain Measurement; Pentoxifyllin | 2014 |
Ischemia and reperfusion of rat small intestine using pentoxyfilline and prostaglandin E1.
Topics: Alprostadil; Animals; Disease Models, Animal; Intestinal Mucosa; Intestine, Small; Ischemia; Male; P | 2013 |
The effect of pentoxifylline on penile cavernosal tissues in ischemic priapism-induced rat model.
Topics: Administration, Oral; Animals; Disease Models, Animal; Electric Stimulation; Ischemia; Male; Pentoxi | 2014 |
Pentoxifylline associated to hypertonic saline solution attenuates inflammatory process and apoptosis after intestinal ischemia/reperfusion in rats.
Topics: Animals; Apoptosis; Caspase 3; Cyclooxygenase 2; Immunohistochemistry; Intestines; Ischemia; Lactic | 2014 |
Pentoxifylline and prostaglandin E1 action on ischemia and reperfusion of small intestine tissue in rats. An immunohistochemical study.
Topics: Alprostadil; Animals; Apoptosis; Disease Models, Animal; Immunohistochemistry; Intestinal Mucosa; In | 2015 |
Pentoxifylline enhances the protective effects of hypertonic saline solution on liver ischemia reperfusion injury through inhibition of oxidative stress.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Capillary Permeability; Disease Models, | 2015 |
Impact of different antithrombotics on the microcirculation and viability of perforator-based ischaemic skin flaps in a small animal model.
Topics: Animals; Aspirin; Clopidogrel; Disease Models, Animal; Fibrinolytic Agents; Graft Survival; Heparin; | 2016 |
Pentoxifylline attenuates the local and systemic inflammatory response after infrarenal abdominal aortic ischemia-reperfusion.
Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Ischemia; Male; Pentoxifylline; Rats; Rats, W | 2017 |
Pentoxifylline augments fasting-induced nephroprotection in acute ischemic kidney injury in rats.
Topics: Acute Kidney Injury; Animal Feed; Animals; Creatinine; Fasting; Ischemia; Kidney Tubules; Male; Neph | 2009 |
Pentoxifylline in ischemia-induced acute kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Cell Respiration; Disease Models, Animal; Free Radical Scavengers; Isc | 2009 |
[Successful treatment of post circumcision glanular ischemia-necrosis with hyperbaric oxygen and intravenous pentoxifylline].
Topics: Child, Preschool; Circumcision, Male; Combined Modality Therapy; Humans; Hyperbaric Oxygenation; Inf | 2012 |
Effect of pentoxifylline and vinpocetine on the healing of ischemic colon anastomosis: an experimental study.
Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Colon; Disease Models, Animal; Female; Ischemia; M | 2011 |
Effect of cilostazol and pentoxifylline on gait biomechanics in rats with ischemic left hindlimb.
Topics: Animals; Biomechanical Phenomena; Cilostazol; Gait; Hindlimb; Ischemia; Male; Pentoxifylline; Rats; | 2012 |
[New data on vasoactive drug. Patients with peripheral arterial occlusive disease walk twice as long].
Topics: Arterial Occlusive Diseases; Clinical Trials as Topic; Exercise Test; Humans; Intermittent Claudicat | 2002 |
Allopurinol plus pentoxifilline in hepatic ischaemia/reperfusion injury.
Topics: Allopurinol; Animals; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Ischemia | 2002 |
Beneficial effect of pentoxifylline on microvesicular steatotic livers submitted to a prolonged cold ischemia.
Topics: Adenosine; Allopurinol; Animals; Fatty Liver; Free Radical Scavengers; Glutathione; Insulin; Ischemi | 2003 |
Ischemic glans penis after circumcision.
Topics: Adult; Circumcision, Male; Humans; Infections; Ischemia; Male; Nerve Block; Penis; Pentoxifylline; V | 2004 |
[Erythrocyte concentrations of adenosine triphosphate (ATP) and magnesium, before and after conservative therapy of lower extremities atherosclerosis].
Topics: Adenosine Triphosphate; Adult; Aged; Arteriosclerosis; Erythrocytes; Female; Humans; Ischemia; Lower | 2004 |
[A new method of treatment of chronic ischemia of extremities with the primary lesion of the distal arterial bed (experimental-clinical investigation)].
Topics: Aged; Animals; Anti-Bacterial Agents; Anticoagulants; Arteriosclerosis; Catheterization; Chronic Dis | 2004 |
Intravenous infusion for the treatment of diabetic and ischaemic non-healing pedal ulcers.
Topics: Adult; Case-Control Studies; Debridement; Diabetic Foot; Female; Foot; Foot Ulcer; Gentamicins; Hepa | 2005 |
Effects of pentoxifylline and vitamin E on the bilateral ovary after experimental ovarian ischemia.
Topics: Animals; Antioxidants; Female; Ischemia; Models, Animal; Ovarian Diseases; Ovary; Pentoxifylline; Ra | 2005 |
[Treatment of freezing injury].
Topics: Blood Viscosity; Cell Death; Cold Temperature; Combined Modality Therapy; Endothelium, Vascular; Foo | 2005 |
[Antinecrotic and antiischemic effect of mexidol and trental in ischemia of the skin graft].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electron Transport Complex II; Graft Surviva | 2005 |
Severe ischemia of the glans penis following circumcision: a successful treatment via pentoxifylline.
Topics: Child; Circumcision, Male; Humans; Ischemia; Male; Penis; Pentoxifylline; Vasodilator Agents | 2005 |
Comparison between intravenous iloprost and vasoactive drugs in limb ischemia IIB severe. A retrospective analysis.
Topics: Adult; Exercise Test; Female; Humans; Iloprost; Ischemia; Leg; Male; Pentoxifylline; Pyrrolidines; R | 2006 |
Pentoxifylline decreases up-regulated nuclear factor kappa B activation and cytokine production in the rat retina following transient ischemia.
Topics: Animals; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Free Radical Scavenge | 2006 |
Effect of pentoxifylline on the healing of ischemic colorectal anastomoses.
Topics: Anastomosis, Surgical; Animals; Chi-Square Distribution; Colon; Hematologic Agents; Ischemia; Pentox | 2007 |
Prolonged transient hand ischaemia secondary to a penicillin skin test.
Topics: Aspirin; Calcium Channel Blockers; Cyanosis; Drug Hypersensitivity; Drug Therapy, Combination; Fibri | 2007 |
[Transcatheteral intra-arterial infusion of drug mixtures in the treatment of severe ischemia of the lower limbs].
Topics: Acetylcholine; Adult; Aged; Catheterization; Dextrans; Diphenhydramine; Drug Combinations; Female; H | 1982 |
The effect of 7-(2'-oxopropyl)-1,3-di-n-butyl-xanthine (BRL 30892) on ischaemic skeletal muscle pO2, pH and contractility in cats and rats.
Topics: Animals; Cats; Female; Hindlimb; Hydrogen-Ion Concentration; Ischemia; Male; Muscle Contraction; Mus | 1984 |
[Pharmacological protection of the kidneys from ischemic damage. The effectiveness of anti-ischemia protection of the kidneys in simulating the terminal state in the donors].
Topics: Animals; Death; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Humans; Hypotension; Isc | 1982 |
[Role and possible control of the risk factors in atherosclerotic vasculopathies for the evaluation of results of surgical treatment. Preliminary study on the use of pentoxifylline].
Topics: Arteriosclerosis; Erythrocytes; Female; Hematocrit; Humans; Ischemia; Leg; Male; Pentoxifylline; Ult | 1981 |
[Trental treatment of spinal and radicular ischemic syndromes in spinal diseases].
Topics: Adolescent; Adult; Aged; Drug Evaluation; Female; Humans; Ischemia; Kyphosis; Male; Microcirculation | 1981 |
[Ischemia and microcirculation].
Topics: Humans; Ischemia; Microcirculation; Pentoxifylline | 1980 |
Pentoxifylline attenuates pulmonary macromolecular leakage after intestinal ischemia-reperfusion.
Topics: Animals; Blood-Air Barrier; Cardiac Output; Disease Models, Animal; Hemodynamics; Intestines; Ischem | 1995 |
[Use of transcatheter intra-arterial infusion of drug mixtures in the combined treatment of patients with obliterating vascular diseases in the terminal stage of limb ischemia].
Topics: Adult; Aged; Amputation, Surgical; Anti-Bacterial Agents; Arterial Occlusive Diseases; Ascorbic Acid | 1994 |
[Liver damage due to normothermic ischemia and reperfusion in the rat. The effects of pentoxifylline pretreatment].
Topics: Animals; Drug Evaluation, Preclinical; Ischemia; Liver; Liver Diseases; Male; Necrosis; Pentoxifylli | 1995 |
L-arginine and pentoxifylline attenuate endothelial dysfunction after lung reperfusion injury in the rabbit. The Paris-Sud University Lung Transplant Group.
Topics: Acetylcholine; Animals; Arginine; Blood; Cardiopulmonary Bypass; Cold Temperature; Endothelium, Vasc | 1995 |
Acute mesenteric ischemia/reperfusion down regulates renal PGE2 synthesis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Constriction; Dinoprostone; Heart Rate; In Vi | 1995 |
[How should we treat intestinal ischemia?--II: Effects of pentoxifylline, glucagon and prostaglandin E1].
Topics: Alprostadil; Animals; Dogs; Glucagon; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Isc | 1995 |
Effect of torbafylline on muscle blood flow, performance, and capillary supply in ischemic muscles subjected to varying levels of activity.
Topics: Animals; Body Weight; Capillaries; Electric Stimulation; Electrodes, Implanted; Ischemia; Isometric | 1994 |
Treating peripheral arterial occlusive disease: pentoxifylline vs exercise.
Topics: Aged; Antigens, CD; Arterial Occlusive Diseases; CD11 Antigens; CD18 Antigens; Cell Adhesion Molecul | 1994 |
Pentoxifylline reduces skeletal muscle necrosis after acute hindlimb ischemia in rats.
Topics: Acute Disease; Animals; Hindlimb; Ischemia; Male; Muscles; Necrosis; Pentoxifylline; Rats; Rats, Wis | 1994 |
Pentoxifylline for ischemic pain in pseudoxanthoma elasticum.
Topics: Abdominal Pain; Adult; Female; Humans; Ischemia; Leg; Pain; Pentoxifylline; Pseudoxanthoma Elasticum | 1993 |
The effect of pentoxifylline on ischemia and reperfusion injury in the rat cremaster muscle.
Topics: Animals; Arteries; Blood Flow Velocity; Cell Adhesion; Cell Aggregation; Ischemia; Leukocytes; Male; | 1994 |
Free radical scavengers prevent intestinal ischemia-reperfusion-mediated cardiac dysfunction.
Topics: Animals; Catalase; Constriction; Free Radical Scavengers; Heart Diseases; Heart Rate; Intestines; Is | 1993 |
Fine structure of capillaries in ischaemic and non ischaemic rat striated muscle. Effect of torbafylline.
Topics: Animals; Capillaries; Electric Stimulation; Ischemia; Male; Muscles; Pentoxifylline; Rats; Rats, Spr | 1993 |
Correlation of function and energy metabolism in rat ischemic skeletal muscle by 31P-NMR spectroscopy: effects of torbafylline.
Topics: Animals; Disease Models, Animal; Electric Stimulation; Hydrogen-Ion Concentration; Ischemia; Magneti | 1993 |
Leukocyte adherence in an ischemic muscle perfused by a collateral circulation.
Topics: Animals; Arterioles; Cell Adhesion; Collateral Circulation; Ischemia; Macrophage Activation; Microci | 1995 |
Pentoxifylline and lung ischemia-reperfusion injury: application to lung transplantation. Université Paris-Sud Lung Transplant Group.
Topics: Animals; Endothelium, Vascular; Ischemia; Lung Transplantation; Neutrophils; Pentoxifylline; Pulmona | 1995 |
Cyclosporine nephrotoxicity in the ischemic kidney and the protective effect of pentoxifylline--a study in the rat.
Topics: Animals; Calcinosis; Creatinine; Cyclosporine; Ischemia; Kidney; Kidney Diseases; Kidney Tubules; Li | 1996 |
Nephroprotective mechanism(s) of pentoxifylline: reduction of erythrocyte-mediated vascular congestion and inhibition of nitric oxide release.
Topics: Animals; Erythrocytes; Ischemia; Kidney; Kidney Diseases; Male; Nitric Oxide; Pentoxifylline; Periph | 1996 |
Pentoxifylline prevents endothelial damage due to ischemia and reperfusion injury.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Femoral Artery; In Vitro Techniques; Ischemia; Norepi | 1997 |
Effect of pentoxifylline on hepatic ischemia and reperfusion injury.
Topics: Administration, Oral; Animals; Injections, Intravenous; Ischemia; Liver; Liver Circulation; Pentoxif | 1997 |
Downstream effects of splanchnic ischemia-reperfusion injury on renal function and eicosanoid release.
Topics: Allopurinol; Animals; Blood Pressure; Eicosanoids; Imidazoles; In Vitro Techniques; Inulin; Ischemia | 1997 |
On the pharmacologic protection of the liver and intestine during ischemia.
Topics: Animals; Humans; Intestines; Ischemia; Liver; Liver Circulation; Pentoxifylline; Rabbits; Vasodilato | 1998 |
Effect of isobaric oxygen versus hyperbaric oxygen on the normal and noise-damaged hypoxic and ischemic guinea pig inner ear.
Topics: Action Potentials; Animals; Cochlea; Evoked Potentials, Auditory; Guinea Pigs; Hearing Loss, Noise-I | 1998 |
Pentoxifylline attenuates reperfusion injury in skeletal muscle after partial ischemia.
Topics: Animals; Ischemia; Leukocytes; Male; Membrane Potentials; Microcirculation; Muscle, Skeletal; Pentox | 1998 |
Pentoxifylline and N-acetylcysteine in hepatic ischemia/reperfusion injury.
Topics: Acetylcysteine; Animals; Catalase; Female; Free Radical Scavengers; Free Radicals; Glutathione; Glut | 1998 |
Lisofylline ameliorates intestinal mucosal barrier dysfunction caused by ischemia and ischemia/reperfusion.
Topics: Adenosine Triphosphate; Animals; Cell Membrane Permeability; Glutathione; Intestinal Mucosa; Intesti | 1999 |
[Enhancement of the anti-ischemic kidney resistance by adaptive hypoxic conditioning and drug therapy].
Topics: Adaptation, Physiological; Animals; Antioxidants; Drug Synergism; Female; Hypoxia; Ischemia; Liver; | 1999 |
[Is blood circulation promoting therapy in disorders of cochleo-vestibular function effective?].
Topics: Animals; Blood Flow Velocity; Calcium Channel Blockers; Cochlea; Flunarizine; Guinea Pigs; Humans; I | 1999 |
[Digital ischemia as paraneoplastic marker of metastatic endometrial carcinoma].
Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Captopril; Cystadenocarcinoma, Papillary; Diagnosis, Dif | 1999 |
Effects of pentoxifylline and coenzyme Q10 in hepatic ischemia/reperfusion injury.
Topics: Animals; Catalase; Coenzymes; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hematologi | 1999 |
The effect of blood flow promoting drugs on cochlear blood flow, perilymphatic pO(2) and auditory function in the normal and noise-damaged hypoxic and ischemic guinea pig inner ear.
Topics: Animals; Betahistine; Cochlea; Ear, Inner; Female; Ginkgo biloba; Guinea Pigs; Hearing Loss, Noise-I | 2000 |
Protective effect of TA-993, a novel therapeutic agent for peripheral circulatory insufficiency, on skeletal muscle fatigue in a rat model of hindlimb ischemia.
Topics: Animals; Blood Pressure; Blood Viscosity; Diltiazem; Heart Rate; Hindlimb; Ischemia; Muscle Fatigue; | 2000 |
Tumor necrosis factor alpha, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver.
Topics: Animals; Antigens, CD; Apoptosis; Fas Ligand Protein; fas Receptor; Hepatocytes; In Situ Nick-End La | 2002 |
[Prolonged intra-arterial therapy in surgical treatment of patients with critical lower limb ischemia].
Topics: Actihaemyl; Adult; Aged; Aged, 80 and over; Amputation, Surgical; Anticoagulants; Critical Care; Dip | 2001 |
Effects of pentoxifylline on cerebral ultrastructure of normal and ischemic gerbils.
Topics: Animals; Brain; Cerebral Cortex; Female; Gerbillinae; Hippocampus; Ischemia; Male; Mitochondria; Pen | 1977 |
[Drug therapy of chronic tissue ischemia with improvement of microcirculation].
Topics: Adult; Blood Vessel Prosthesis; Chronic Disease; Extremities; Humans; Ischemia; Ischemic Attack, Tra | 1978 |
Pentoxifylline preserves small-intestine microvascular blood flow during bacteremia.
Topics: Animals; Bacteremia; Blood Pressure; Cardiac Output; Heart Rate; Hemodynamics; Intestinal Mucosa; Is | 1992 |
Expansion of contracted visual fields following treatment with pentoxifylline in two patients with coexistent peripheral vascular disease--case reports.
Topics: Aged; Humans; Intermittent Claudication; Ischemia; Leg; Male; Middle Aged; Pentoxifylline; Periphera | 1992 |
The effect of torbafylline on enzyme activities in fast and slow muscles with limited blood supply.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Animals; Citrate (si)-Synthase; Iliac Artery; Ischemia; L-Lactate | 1991 |
Haemorheological treatment of ischaemia--facts or fancy?
Topics: Blood Viscosity; Hemodilution; Humans; Ischemia; Pentoxifylline; Rheology | 1991 |
Effect of pentoxiphylline on the recovery of the preserved rat liver: 31P NMR and ultrastructural studies.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cryopreservation; Erythrocytes; Ischemia; | 1991 |
Skeletal muscle microcirculation: the effects of limited blood supply and treatment with torbafylline.
Topics: Animals; Arterioles; Capillaries; Glycolysis; Iliac Artery; Ischemia; Ligation; Male; Microcirculati | 1990 |
Drug effects on function in the ferret ischemic hindlimb.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Ferrets; Hindlimb; | 1990 |
The influence of pentoxifylline and torbafylline on muscle blood flow in animals with peripheral arterial insufficiency.
Topics: Animals; Drug Evaluation, Preclinical; Hindlimb; Ischemia; Male; Pentoxifylline; Physical Exertion; | 1990 |
The effects of torbafylline on blood flow, pO2 and function of rat ischaemic skeletal muscle.
Topics: Acute Disease; Animals; Blood Pressure; Erythrocytes; Hindlimb; Ischemia; Lactates; Male; Microspher | 1989 |
[Lipid metabolism and peripheral hemodynamics in arteriosclerosis obliterans treated with nifedipine--a comparison with pentoxifylline].
Topics: Arteriosclerosis Obliterans; Hemodynamics; Humans; Ischemia; Leg; Lipids; Male; Middle Aged; Nifedip | 1989 |
[Pharmacologic correction of the adverse effects of beta-adrenoblockaders on the kidneys in patients with hypertension].
Topics: Adult; Aged; Female; Humans; Hypertension; Ischemia; Kidney; Male; Middle Aged; Pentoxifylline; Prop | 1989 |
Intravenous pentoxifylline in the treatment of rest pain: a preliminary report.
Topics: Aged; Female; Humans; Injections, Intravenous; Ischemia; Leg; Male; Pain; Pentoxifylline; Pilot Proj | 1989 |
Effect of pentoxifylline on the ischemic rat kidney monitored by 31P NMR spectroscopy in vivo.
Topics: Adenine Nucleotides; Animals; Energy Metabolism; Ischemia; Kidney; Magnetic Resonance Spectroscopy; | 1988 |
[Nutritive skin circulation in partial ischemia: effect of various vasoactive substances].
Topics: Animals; Furans; Ischemia; Mice; Mice, Hairless; Nafronyl; Pentoxifylline; Pyrrolidines; Regional Bl | 1988 |
[Microcirculatory disorders and their correction in patients with acute ulcer-related gastrointestinal hemorrhage].
Topics: Aged; Gastric Mucosa; Humans; Ischemia; Microcirculation; Middle Aged; Pentoxifylline; Peptic Ulcer | 1988 |
Pentoxifylline in end-stage renal disease.
Topics: Adult; Dose-Response Relationship, Drug; Female; Hand; Humans; Ischemia; Kidney Failure, Chronic; Pe | 1987 |
[Intra-arterial therapy of arterial occlusive diseases of the extremities].
Topics: Actihaemyl; Adenosine Triphosphate; Anti-Bacterial Agents; Arterial Occlusive Diseases; Drug Therapy | 1987 |
Pentoxifylline for mesenteric ischemia.
Topics: Humans; Ischemia; Mesenteric Arteries; Mesenteric Vascular Occlusion; Pentoxifylline; Theobromine | 1987 |
[Changes in the rate of surface blood microcirculation studied by photon-correlation spectroscopy in the practical treatment and diagnosis of diabetes mellitus].
Topics: Adolescent; Adult; Aged; Blood Flow Velocity; Conjunctiva; Diabetes Mellitus, Type 1; Diabetes Melli | 1985 |
Pentoxifylline treatment of moderate to severe chronic occlusive arterial disease.
Topics: Aged; Arterial Occlusive Diseases; Exercise Test; Humans; Intermittent Claudication; Ischemia; Leg; | 1985 |