pentoxifylline has been researched along with Injuries, Radiation in 40 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To conduct a randomized clinical trial to determine whether the combination of pentoxifylline (PTX) and vitamin E given for 6 months after breast/chest wall irradiation effectively prevents radiation-induced fibrosis (RIF)." | 9.17 | Randomized trial of pentoxifylline and vitamin E vs standard follow-up after breast irradiation to prevent breast fibrosis, evaluated by tissue compliance meter. ( Bhatia, S; Bodeker, K; Buatti, J; Button, AM; Jacobson, G; Smith, BJ, 2013) |
| " Women with breast cancer were treated for 12 months with 400 mg pentoxifylline t." | 9.14 | Pentoxifylline and vitamin E treatment for prevention of radiation-induced side-effects in women with breast cancer: a phase two, double-blind, placebo-controlled randomised clinical trial (Ptx-5). ( Höglund, P; Johansson, K; Jönsson, C; Killander, F; Kjellén, E; Magnusson, M; Malmström, P; Weddig, A, 2009) |
| "In an open label drug trial, we studied the effects of pentoxifylline (400 mg orally tid for 8 weeks) on 30 patients who displayed late, radiation-induced fibrosis at 1 to 29 years posttreatment (40 to 84 Gy)." | 9.11 | Pentoxifylline in the treatment of radiation-induced fibrosis. ( Abraham, EH; Altemus, RM; Augustine, E; Coleman, N; Cornelison, TL; Ding, I; Gerber, LH; Hicks, JE; Huser, AK; Naydich, BG; Okunieff, P; Smith, JJ, 2004) |
| "To evaluate the use of pentoxifylline and vitamin E as monotherapy and in combination for the treatment of radiation-induced fibrosis (RIF)." | 8.82 | Role of pentoxifylline and vitamin E in attenuation of radiation-induced fibrosis. ( Chiao, TB; Lee, AJ, 2005) |
| " Two patients with progressive worsening RI lumbosacral polyradiculopathy experienced over several years a significant clinical improvement in their neurological sensorimotor symptoms with long-term pentoxifylline-tocopherol-clodronate treatment, and good safety." | 7.74 | Significant clinical improvement in radiation-induced lumbosacral polyradiculopathy by a treatment combining pentoxifylline, tocopherol, and clodronate (Pentoclo). ( Delanian, S; Lefaix, JL; Maisonobe, T; Pradat, PF; Salachas, F, 2008) |
| "Of 30 patients with radiation-induced proctitis/enteritis grade I-II according to the RTOG/EORTC toxicity criteria, 21 were treated with pentoxifylline and tocopherol." | 7.73 | Effect of pentoxifylline and tocopherol on radiation proctitis/enteritis. ( Christiansen, H; Hermann, RM; Hess, CF; Hilgers, R; Hille, A; Pradier, O; Schmidberger, H; Siekmeyer, B; Weiss, E, 2005) |
| "Between September 1988 and August 1989, 12 patients with 15 sites of late radiation necrosis of the soft tissues were treated with pentoxifylline, a hemorrheologic agent that has been used to treat a variety of vasculo-occlusive disorders." | 7.68 | Preliminary results of a pilot study of pentoxifylline in the treatment of late radiation soft tissue necrosis. ( Anderson, B; Dion, MW; Doornbos, JF; Hussey, DH; Vigliotti, AP; Wen, BC, 1990) |
| "Radiation-induced fibrosis is a side effect of radiation therapy and may occur in up to 13% of the cases in patients (Radiother Oncol, 2009;90:80), fortunately usually is modest/localized and not associated with marked symptoms." | 6.58 | Pentoxifylline and vitamin E for treatment or prevention of radiation-induced fibrosis in patients with breast cancer. ( Jones, EL; Kaidar-Person, O; Marks, LB, 2018) |
| " One experimental group of 5 pigs was dosed orally for 26 weeks starting 26 weeks after irradiation with 1600 mg/120 kg body weight of pentoxifylline (PTX) included in the reconstituted food during its fabrication, and another group of 5 was dosed orally for the same period with a daily dose of 1600 mg/120 kg body weight of PTX combined with 2000 IU/120 kg body weight of alpha-tocopherol." | 5.30 | Striking regression of subcutaneous fibrosis induced by high doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: an experimental study. ( Delanian, S; Lefaix, JL; Leplat, JJ; Martin, M; Tricaud, Y; Vozenin, MC, 1999) |
| "To conduct a randomized clinical trial to determine whether the combination of pentoxifylline (PTX) and vitamin E given for 6 months after breast/chest wall irradiation effectively prevents radiation-induced fibrosis (RIF)." | 5.17 | Randomized trial of pentoxifylline and vitamin E vs standard follow-up after breast irradiation to prevent breast fibrosis, evaluated by tissue compliance meter. ( Bhatia, S; Bodeker, K; Buatti, J; Button, AM; Jacobson, G; Smith, BJ, 2013) |
| " Women with breast cancer were treated for 12 months with 400 mg pentoxifylline t." | 5.14 | Pentoxifylline and vitamin E treatment for prevention of radiation-induced side-effects in women with breast cancer: a phase two, double-blind, placebo-controlled randomised clinical trial (Ptx-5). ( Höglund, P; Johansson, K; Jönsson, C; Killander, F; Kjellén, E; Magnusson, M; Malmström, P; Weddig, A, 2009) |
| "In an open label drug trial, we studied the effects of pentoxifylline (400 mg orally tid for 8 weeks) on 30 patients who displayed late, radiation-induced fibrosis at 1 to 29 years posttreatment (40 to 84 Gy)." | 5.11 | Pentoxifylline in the treatment of radiation-induced fibrosis. ( Abraham, EH; Altemus, RM; Augustine, E; Coleman, N; Cornelison, TL; Ding, I; Gerber, LH; Hicks, JE; Huser, AK; Naydich, BG; Okunieff, P; Smith, JJ, 2004) |
| "To evaluate the use of pentoxifylline and vitamin E as monotherapy and in combination for the treatment of radiation-induced fibrosis (RIF)." | 4.82 | Role of pentoxifylline and vitamin E in attenuation of radiation-induced fibrosis. ( Chiao, TB; Lee, AJ, 2005) |
| " Two patients with progressive worsening RI lumbosacral polyradiculopathy experienced over several years a significant clinical improvement in their neurological sensorimotor symptoms with long-term pentoxifylline-tocopherol-clodronate treatment, and good safety." | 3.74 | Significant clinical improvement in radiation-induced lumbosacral polyradiculopathy by a treatment combining pentoxifylline, tocopherol, and clodronate (Pentoclo). ( Delanian, S; Lefaix, JL; Maisonobe, T; Pradat, PF; Salachas, F, 2008) |
| "Of 30 patients with radiation-induced proctitis/enteritis grade I-II according to the RTOG/EORTC toxicity criteria, 21 were treated with pentoxifylline and tocopherol." | 3.73 | Effect of pentoxifylline and tocopherol on radiation proctitis/enteritis. ( Christiansen, H; Hermann, RM; Hess, CF; Hilgers, R; Hille, A; Pradier, O; Schmidberger, H; Siekmeyer, B; Weiss, E, 2005) |
| "Between September 1988 and August 1989, 12 patients with 15 sites of late radiation necrosis of the soft tissues were treated with pentoxifylline, a hemorrheologic agent that has been used to treat a variety of vasculo-occlusive disorders." | 3.68 | Preliminary results of a pilot study of pentoxifylline in the treatment of late radiation soft tissue necrosis. ( Anderson, B; Dion, MW; Doornbos, JF; Hussey, DH; Vigliotti, AP; Wen, BC, 1990) |
| "Patients with liver metastases from colorectal carcinoma who were scheduled for local ablation by radiotherapy (image-guided high-dose-rate interstitial brachytherapy) were prospectively randomized to receive PTX, UDCA and LMWH for 8 weeks (treatment) or no medication (control)." | 2.79 | Prospective randomized trial of enoxaparin, pentoxifylline and ursodeoxycholic acid for prevention of radiation-induced liver toxicity. ( Damm, R; Gademann, G; Hass, P; Kropf, S; Mohnike, K; Pech, M; Ricke, J; Sangro, B; Seidensticker, M; Seidensticker, R; Wust, P, 2014) |
| " We recommend the prophylactic use of Ptx, finding it to be safe and effective." | 2.71 | Pentoxifylline in prevention of radiation-induced lung toxicity in patients with breast and lung cancer: a double-blind randomized trial. ( Atavci, S; Egehan, I; Kitapci, M; Ozturk, B, 2004) |
| "Radiation-induced fibrosis is a side effect of radiation therapy and may occur in up to 13% of the cases in patients (Radiother Oncol, 2009;90:80), fortunately usually is modest/localized and not associated with marked symptoms." | 2.58 | Pentoxifylline and vitamin E for treatment or prevention of radiation-induced fibrosis in patients with breast cancer. ( Jones, EL; Kaidar-Person, O; Marks, LB, 2018) |
| "In the future, these treatments of fibrosis and necrosis should include targeted drugs (such as growth factors) to take organ specificities into account." | 2.44 | Current management for late normal tissue injury: radiation-induced fibrosis and necrosis. ( Delanian, S; Lefaix, JL, 2007) |
| "Radiation enteritis is a severe problem in patients receiving irradiation of the abdomen or pelvis in the course of cancer treatment." | 2.44 | Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review. ( Böcker, U; Singer, MV; Wenz, F; Zimmerer, T, 2008) |
| "Oral mucositis is a frequent early side effect of radio(chemo)therapy of head-and-neck malignancies." | 1.42 | Modulation of radiation-induced oral mucositis by pentoxifylline: preclinical studies. ( Bozsaky, E; Dörr, W; Gruber, S; Haagen, J; Habelt, B; Puttrich, M; Schmidt, M; Wolfram, K, 2015) |
| "Pentoxifylline is a methylxanthine derivative that produces dose-related hemorrheologic effects, lower blood viscosity, improved erythrocyte flexibility, and increased tissue oxygen levels." | 1.30 | Pentoxifylline in the treatment of radiation-related soft tissue injury: preliminary observations. ( Futran, ND; Gwede, C; Trotti, A, 1997) |
| " One experimental group of 5 pigs was dosed orally for 26 weeks starting 26 weeks after irradiation with 1600 mg/120 kg body weight of pentoxifylline (PTX) included in the reconstituted food during its fabrication, and another group of 5 was dosed orally for the same period with a daily dose of 1600 mg/120 kg body weight of PTX combined with 2000 IU/120 kg body weight of alpha-tocopherol." | 1.30 | Striking regression of subcutaneous fibrosis induced by high doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: an experimental study. ( Delanian, S; Lefaix, JL; Leplat, JJ; Martin, M; Tricaud, Y; Vozenin, MC, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (12.50) | 18.2507 |
| 2000's | 17 (42.50) | 29.6817 |
| 2010's | 15 (37.50) | 24.3611 |
| 2020's | 3 (7.50) | 2.80 |
| Authors | Studies |
|---|---|
| Vaios, EJ | 1 |
| Batich, KA | 1 |
| Buckley, AF | 1 |
| Dunn-Pirio, A | 1 |
| Patel, MP | 1 |
| Kirkpatrick, JP | 1 |
| Goudar, R | 1 |
| Peters, KB | 1 |
| Lambrescak, E | 1 |
| Delanian, S | 8 |
| Delanian, SE | 1 |
| Lenglet, T | 1 |
| Maisonobe, T | 2 |
| Resche-Rigon, M | 1 |
| Pradat, PF | 2 |
| McLaughlin, MF | 1 |
| Donoviel, DB | 1 |
| Jones, JA | 1 |
| Kumar, D | 1 |
| Yalamanchali, S | 1 |
| New, J | 1 |
| Parsel, S | 1 |
| New, N | 1 |
| Holcomb, A | 1 |
| Gunewardena, S | 1 |
| Tawfik, O | 1 |
| Lominska, C | 1 |
| Kimler, BF | 1 |
| Anant, S | 1 |
| Kakarala, K | 1 |
| Tsue, T | 1 |
| Shnayder, Y | 1 |
| Sykes, K | 1 |
| Padhye, S | 1 |
| Thomas, SM | 1 |
| Kaidar-Person, O | 1 |
| Marks, LB | 1 |
| Jones, EL | 1 |
| Sridharan, V | 1 |
| Tripathi, P | 1 |
| Sharma, S | 1 |
| Corry, PM | 1 |
| Moros, EG | 1 |
| Singh, A | 1 |
| Compadre, CM | 1 |
| Hauer-Jensen, M | 2 |
| Boerma, M | 1 |
| Hamama, S | 1 |
| Noman, MZ | 1 |
| Gervaz, P | 1 |
| Vozenin, MC | 2 |
| Gruber, S | 2 |
| Schmidt, M | 2 |
| Bozsaky, E | 2 |
| Wolfram, K | 1 |
| Haagen, J | 1 |
| Habelt, B | 1 |
| Puttrich, M | 1 |
| Dörr, W | 2 |
| Seidensticker, M | 1 |
| Seidensticker, R | 1 |
| Damm, R | 1 |
| Mohnike, K | 1 |
| Pech, M | 1 |
| Sangro, B | 1 |
| Hass, P | 1 |
| Wust, P | 1 |
| Kropf, S | 1 |
| Gademann, G | 1 |
| Ricke, J | 1 |
| Vilar-González, S | 1 |
| Lamas-Oliveira, C | 1 |
| Fagúndez-Vargas, MA | 1 |
| Núñez-Quintanilla, AT | 1 |
| Pérez-Rozos, A | 1 |
| Merayo-Lloves, J | 1 |
| Escobar-Barranco, JJ | 1 |
| Rico-Pérez, JM | 1 |
| Patel, V | 1 |
| McGurk, M | 1 |
| Roitinger, E | 1 |
| Schwarz, K | 1 |
| Lefaix, JL | 4 |
| Salachas, F | 1 |
| Liu, H | 1 |
| Xiong, M | 1 |
| Xia, YF | 1 |
| Cui, NJ | 1 |
| Lu, RB | 1 |
| Deng, L | 1 |
| Lin, YH | 1 |
| Rong, TH | 1 |
| Magnusson, M | 1 |
| Höglund, P | 1 |
| Johansson, K | 1 |
| Jönsson, C | 1 |
| Killander, F | 1 |
| Malmström, P | 1 |
| Weddig, A | 1 |
| Kjellén, E | 1 |
| Thariat, J | 1 |
| de Mones, E | 1 |
| Darcourt, V | 1 |
| Poissonnet, G | 1 |
| Marcy, PY | 1 |
| Guevara, N | 1 |
| Bozec, A | 1 |
| Ortholan, C | 1 |
| Santini, J | 1 |
| Bensadoun, RJ | 1 |
| Dassonville, O | 1 |
| Giuliari, GP | 1 |
| Sadaka, A | 1 |
| Hinkle, DM | 1 |
| Simpson, ER | 1 |
| Shoma, A | 1 |
| Eldars, W | 1 |
| Noman, N | 1 |
| Saad, M | 1 |
| Elzahaf, E | 1 |
| Abdalla, M | 1 |
| Eldin, DS | 1 |
| Zayed, D | 1 |
| Shalaby, A | 1 |
| Malek, HA | 1 |
| Berbée, M | 1 |
| Fu, Q | 1 |
| Garg, S | 1 |
| Kulkarni, S | 1 |
| Kumar, KS | 1 |
| Jacobson, G | 1 |
| Bhatia, S | 1 |
| Smith, BJ | 1 |
| Button, AM | 1 |
| Bodeker, K | 1 |
| Buatti, J | 1 |
| Ozturk, B | 1 |
| Egehan, I | 1 |
| Atavci, S | 1 |
| Kitapci, M | 1 |
| Moulder, JE | 1 |
| Aygenc, E | 1 |
| Celikkanat, S | 1 |
| Kaymakci, M | 1 |
| Aksaray, F | 1 |
| Ozdem, C | 1 |
| Okunieff, P | 1 |
| Augustine, E | 1 |
| Hicks, JE | 1 |
| Cornelison, TL | 1 |
| Altemus, RM | 1 |
| Naydich, BG | 1 |
| Ding, I | 1 |
| Huser, AK | 1 |
| Abraham, EH | 1 |
| Smith, JJ | 1 |
| Coleman, N | 1 |
| Gerber, LH | 1 |
| Chiao, TB | 1 |
| Lee, AJ | 1 |
| Hille, A | 1 |
| Christiansen, H | 1 |
| Pradier, O | 1 |
| Hermann, RM | 1 |
| Siekmeyer, B | 1 |
| Weiss, E | 1 |
| Hilgers, R | 1 |
| Hess, CF | 1 |
| Schmidberger, H | 1 |
| Spadaro, JA | 1 |
| Horton, JA | 1 |
| Margulies, BS | 1 |
| Luther, J | 1 |
| Strauss, JA | 1 |
| Farnum, CE | 1 |
| Damron, TA | 1 |
| Misirlioglu, CH | 1 |
| Demirkasimoglu, T | 1 |
| Kucukplakci, B | 1 |
| Sanri, E | 1 |
| Altundag, K | 1 |
| Jellett, L | 1 |
| Harrison, C | 1 |
| McAleese, J | 1 |
| Venkitaraman, R | 1 |
| Price, A | 1 |
| Coffey, J | 1 |
| Norman, AR | 1 |
| James, FV | 1 |
| Huddart, RA | 1 |
| Horwich, A | 1 |
| Dearnaley, DP | 1 |
| Zimmerer, T | 1 |
| Böcker, U | 1 |
| Wenz, F | 1 |
| Singer, MV | 1 |
| Futran, ND | 1 |
| Trotti, A | 1 |
| Gwede, C | 1 |
| Leplat, JJ | 1 |
| Tricaud, Y | 1 |
| Martin, M | 1 |
| Balla-Mekias, S | 1 |
| Gupta, P | 1 |
| Meisenberg, B | 1 |
| Amin, P | 1 |
| Pomeranz, HD | 1 |
| Letur-Könirsch, H | 1 |
| Guis, F | 1 |
| Dion, MW | 1 |
| Hussey, DH | 1 |
| Doornbos, JF | 1 |
| Vigliotti, AP | 1 |
| Wen, BC | 1 |
| Anderson, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Preventive Effect of Enoxaparin, Pentoxifylline and Ursodeoxycholic Acid to Radiation Induced Liver Toxicity After Brachytherapy of Liver Metastases From Colorectal Carcinoma, Assessed in a Prospective Randomised Trial[NCT01149304] | Phase 2 | 22 participants (Actual) | Interventional | 2009-06-30 | Completed | ||
| Pentoxifylline and Tocopherol (PENTO) in the Treatment of Medication-related Osteonecrosis of the Jaw (MRONJ): A Prospective, Randomized Controlled Trial to Evaluate a Novel Non-operative Treatment[NCT03040778] | Phase 3 | 100 participants (Anticipated) | Interventional | 2018-04-01 | Enrolling by invitation | ||
| A Pilot Study of Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients[NCT05637216] | Phase 2 | 40 participants (Anticipated) | Interventional | 2023-08-17 | Recruiting | ||
| Evaluation of the Medical Benefit of a Spa Therapy on the Evolutionary Genius of Late Sequelae Fibrosis After Postoperative Radiotherapy for Breast Cancer in Remission[NCT05874492] | 110 participants (Anticipated) | Interventional | 2023-09-30 | Not yet recruiting | |||
| Postoperative or Salvage Radiotherapy for Node Negative Prostate Cancer Following Radical Prostatectomy[NCT00969111] | 70 participants (Anticipated) | Interventional | 2009-08-31 | Recruiting | |||
| An Expanded Phase II Study of Hypofractionated Dose Intense Image Guided Proton Radiation Therapy for Low and Intermediate Risk Adenocarcinoma of the Prostate[NCT01368055] | 361 participants (Actual) | Interventional | 2011-09-30 | Active, not recruiting | |||
| Development of Radiation Fibrosis in Patients Treated With Pentoxyphylline and Vitamin E: a Prospective Randomized Study[NCT00583700] | Phase 2 | 54 participants (Actual) | Interventional | 2003-02-28 | Completed | ||
| Multicenter Prospective Evaluation of a Predictive Test of Late Toxicities After Radiotherapy by the Rate of Radiation Induced CD8 T-Lymphocyte Apoptosis: Application to Breast and Prostate Cancers.[NCT00893035] | 885 participants (Actual) | Observational | 2006-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
A primary outcome of interest is the composite Subjective, Objective, Management, and Analytic (SOMA) score at 18-month follow-up visit. Maximum score is 45, with a score of 0 being ideal and representing no treatment-related side effects at the study visit. (NCT00583700)
Timeframe: 18 month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Control Arm | 1.59 |
| Intervention: Pentoxifylline & Vitamin E | 1.0 |
"Tissue compliance meter measurements of the treated breast compared to the non-treated breast were obtained at 18 months post-radiation therapy. Tissue compliance simply means how soft and pliable the breast tissue is when force is applied to it.~One physician would hold the tissue compliance meter (TCM) against the participant's skin. A standard amount of force would be applied. A second physician would read the displacement scale for a specific set of areas on the breast. The range of the scale was 0 to 60 milimeters (mm). The physician's were blineded to the participant's intervention at the time of measurement.~The final value is the difference between the untreated and the treated breast [untreated - treated]. The range of these differences was -3.3 to 7.0 mm." (NCT00583700)
Timeframe: 18 months post-treatment
| Intervention | milimeters (mm) (Mean) |
|---|---|
| Control Arm | 2.10 |
| Intervention: Pentoxifylline & Vitamin E | 0.88 |
10 reviews available for pentoxifylline and Injuries, Radiation
| Article | Year |
|---|---|
Novel Indications for Commonly Used Medications as Radiation Protectants in Spaceflight.
Topics: Acetylcysteine; Adrenergic beta-Antagonists; Aerospace Medicine; Angiotensin Receptor Antagonists; A | 2017 |
Pentoxifylline and vitamin E for treatment or prevention of radiation-induced fibrosis in patients with breast cancer.
Topics: Breast Neoplasms; Female; Fibrosis; Humans; Pentoxifylline; Radiation Injuries; Radiation-Protective | 2018 |
[Thyroid orbitopathy, an overview with special attention to the role of radiotherapy].
Topics: Adrenal Cortex Hormones; Combined Modality Therapy; Decompression, Surgical; Double-Blind Method; Fe | 2015 |
Use of pentoxifylline and tocopherol in radiation-induced fibrosis and fibroatrophy.
Topics: Antioxidants; Atrophy; Fibrosis; Humans; Pentoxifylline; Radiation Injuries; Radiotherapy; Tocophero | 2017 |
[Teeth and irradiation: dental care and treatment of osteoradionecrosis after irradiation in head and neck cancer].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Dental Care; Fluorides; Head and Nec | 2010 |
Current treatments for radiation retinopathy.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, H | 2011 |
Post-irradiation approaches to treatment of radiation injuries in the context of radiological terrorism and radiation accidents: a review.
Topics: Abnormalities, Radiation-Induced; Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; A | 2004 |
Role of pentoxifylline and vitamin E in attenuation of radiation-induced fibrosis.
Topics: Antioxidants; Clinical Trials as Topic; Drug Therapy, Combination; Fibrosis; Humans; Pentoxifylline; | 2005 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review.
Topics: Abdominal Neoplasms; Acute Disease; Chronic Disease; Combined Modality Therapy; Controlled Clinical | 2008 |
11 trials available for pentoxifylline and Injuries, Radiation
| Article | Year |
|---|---|
Randomized, Placebo-Controlled Clinical Trial Combining Pentoxifylline-Tocopherol and Clodronate in the Treatment of Radiation-Induced Plexopathy.
Topics: Aged; Clodronic Acid; Drug Combinations; Female; Humans; Male; Middle Aged; Pentoxifylline; Peripher | 2020 |
Prospective randomized trial of enoxaparin, pentoxifylline and ursodeoxycholic acid for prevention of radiation-induced liver toxicity.
Topics: Aged; Aged, 80 and over; Brachytherapy; Colorectal Neoplasms; Enoxaparin; Female; Humans; Liver Neop | 2014 |
Pentoxifylline and vitamin E treatment for prevention of radiation-induced side-effects in women with breast cancer: a phase two, double-blind, placebo-controlled randomised clinical trial (Ptx-5).
Topics: Aged; Antioxidants; Breast Neoplasms; Double-Blind Method; Drug Therapy, Combination; Female; Humans | 2009 |
Pentoxifylline and local honey for radiation-induced burn following breast conservative surgery.
Topics: Adult; Aged; Breast Neoplasms; Drug Therapy, Combination; Female; Honey; Humans; Mastectomy, Segment | 2010 |
Randomized trial of pentoxifylline and vitamin E vs standard follow-up after breast irradiation to prevent breast fibrosis, evaluated by tissue compliance meter.
Topics: Adult; Aged; Aged, 80 and over; Breast; Breast Neoplasms; Compliance; Drug Therapy, Combination; Fem | 2013 |
Randomized trial of pentoxifylline and vitamin E vs standard follow-up after breast irradiation to prevent breast fibrosis, evaluated by tissue compliance meter.
Topics: Adult; Aged; Aged, 80 and over; Breast; Breast Neoplasms; Compliance; Drug Therapy, Combination; Fem | 2013 |
Randomized trial of pentoxifylline and vitamin E vs standard follow-up after breast irradiation to prevent breast fibrosis, evaluated by tissue compliance meter.
Topics: Adult; Aged; Aged, 80 and over; Breast; Breast Neoplasms; Compliance; Drug Therapy, Combination; Fem | 2013 |
Randomized trial of pentoxifylline and vitamin E vs standard follow-up after breast irradiation to prevent breast fibrosis, evaluated by tissue compliance meter.
Topics: Adult; Aged; Aged, 80 and over; Breast; Breast Neoplasms; Compliance; Drug Therapy, Combination; Fem | 2013 |
Pentoxifylline in prevention of radiation-induced lung toxicity in patients with breast and lung cancer: a double-blind randomized trial.
Topics: Adult; Breast Neoplasms; Female; Humans; Lung Diseases; Lung Neoplasms; Male; Middle Aged; Pentoxify | 2004 |
Prophylactic effect of pentoxifylline on radiotherapy complications: a clinical study.
Topics: Aged; Carcinoma, Squamous Cell; Chemoprevention; Head and Neck Neoplasms; Humans; Male; Middle Aged; | 2004 |
Pentoxifylline in the treatment of radiation-induced fibrosis.
Topics: Adolescent; Adult; Aged; Cytokines; Fibrosis; Humans; Middle Aged; Pentoxifylline; Radiation Injurie | 2004 |
Pentoxifylline and alpha-tocopherol in prevention of radiation-induced lung toxicity in patients with lung cancer.
Topics: Adult; Aged; alpha-Tocopherol; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Combined Modal | 2007 |
Pentoxifylline to treat radiation proctitis: a small and inconclusive randomised trial.
Topics: Gastrointestinal Hemorrhage; Humans; Pentoxifylline; Platelet Aggregation Inhibitors; Proctitis; Rad | 2008 |
Uterine restoration by radiation sequelae regression with combined pentoxifylline-tocopherol: a phase II study.
Topics: Adult; Antioxidants; Arteries; Drug Therapy, Combination; Estradiol; Female; Humans; Pentoxifylline; | 2002 |
19 other studies available for pentoxifylline and Injuries, Radiation
| Article | Year |
|---|---|
Resolution of radiation necrosis with bevacizumab following radiation therapy for primary CNS lymphoma.
Topics: Bevacizumab; Brain Neoplasms; Female; Humans; Lymphoma; Male; Middle Aged; Necrosis; Pentoxifylline; | 2022 |
Delayed septic radiation-induced calcinosis cutis long after cured anorectal cancer.
Topics: Anti-Bacterial Agents; Anus Neoplasms; Calcinosis; Clodronic Acid; Drainage; Drug Combinations; Fema | 2020 |
Development and Characterization of an In Vitro Model for Radiation-Induced Fibrosis.
Topics: Cell Movement; Cell Proliferation; Collagen; Curcumin; Extracellular Matrix; Fibroblasts; Fibrosis; | 2018 |
Effects of late administration of pentoxifylline and tocotrienols in an image-guided rat model of localized heart irradiation.
Topics: Administration, Oral; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cell Count; | 2013 |
MiR-210: A potential therapeutic target against radiation-induced enteropathy.
Topics: alpha-Tocopherol; Antioxidants; Cells, Cultured; Drug Therapy, Combination; Fibrosis; Humans; Hypoxi | 2014 |
Modulation of radiation-induced oral mucositis by pentoxifylline: preclinical studies.
Topics: Animals; Disease Models, Animal; Dose Fractionation, Radiation; Female; Male; Mice; Mice, Inbred C3H | 2015 |
Early inflammatory changes in radiation-induced oral mucositis : Effect of pentoxifylline in a mouse model.
Topics: Animals; Disease Models, Animal; Dose Fractionation, Radiation; Inflammation Mediators; Mice; Mice, | 2017 |
Significant clinical improvement in radiation-induced lumbosacral polyradiculopathy by a treatment combining pentoxifylline, tocopherol, and clodronate (Pentoclo).
Topics: Antioxidants; Clodronic Acid; Drug Therapy, Combination; Humans; Male; Middle Aged; Pentoxifylline; | 2008 |
Studies on pentoxifylline and tocopherol combination for radiation-induced heart disease in rats.
Topics: Animals; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fibrosis; Heart; Heart Diseases; M | 2009 |
Pentoxifylline enhances the radioprotective properties of γ-tocotrienol: differential effects on the hematopoietic, gastrointestinal and vascular systems.
Topics: Animals; Blood Vessels; Chromans; Drug Synergism; Enzyme Inhibitors; Hematopoiesis; Intestines; Male | 2011 |
Effect of pentoxifylline and tocopherol on radiation proctitis/enteritis.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antioxidants; Chi-Square Distribution; Data In | 2005 |
Radioprotectant combinations spare radiation-induced damage to the physis more than fractionation alone.
Topics: Amifostine; Animals; Anti-Ulcer Agents; Bone Development; Disease Models, Animal; Dose Fractionation | 2005 |
Letter to editor. Re: "Effect of concomitant use of pentoxifylline (PTX) and alpha-tocopherol with radiotherapy on the clinical outcome of patients with stage IIIB non-small cell lung cancer".
Topics: alpha-Tocopherol; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Drug Therapy, Combinati | 2007 |
Pentoxifylline in the treatment of radiation-related soft tissue injury: preliminary observations.
Topics: Administration, Oral; Aged; Analgesics; Anti-Bacterial Agents; Atrophy; Debridement; Dose-Response R | 1997 |
Striking regression of radiation-induced fibrosis by a combination of pentoxifylline and tocopherol.
Topics: Aged; Drug Therapy, Combination; Female; Fibrosis; Humans; Pentoxifylline; Radiation Injuries; Radio | 1998 |
Striking regression of subcutaneous fibrosis induced by high doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: an experimental study.
Topics: Drug Combinations; Fibrosis; Gamma Rays; Humans; Muscle, Skeletal; Pentoxifylline; Radiation Injurie | 1999 |
Striking regression of subcutaneous fibrosis induced by high doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: an experimental study.
Topics: Drug Combinations; Fibrosis; Gamma Rays; Humans; Muscle, Skeletal; Pentoxifylline; Radiation Injurie | 1999 |
Striking regression of subcutaneous fibrosis induced by high doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: an experimental study.
Topics: Drug Combinations; Fibrosis; Gamma Rays; Humans; Muscle, Skeletal; Pentoxifylline; Radiation Injurie | 1999 |
Striking regression of subcutaneous fibrosis induced by high doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: an experimental study.
Topics: Drug Combinations; Fibrosis; Gamma Rays; Humans; Muscle, Skeletal; Pentoxifylline; Radiation Injurie | 1999 |
Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol.
Topics: Adult; Aged; Breast Neoplasms; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; M | 1999 |
Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol.
Topics: Adult; Aged; Breast Neoplasms; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; M | 1999 |
Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol.
Topics: Adult; Aged; Breast Neoplasms; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; M | 1999 |
Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol.
Topics: Adult; Aged; Breast Neoplasms; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; M | 1999 |
Radiation retinopathy: the role of pentoxifylline.
Topics: Adult; Brain Neoplasms; Female; Fluorescein Angiography; Humans; Medulloblastoma; Pentoxifylline; Ra | 2001 |
Preliminary results of a pilot study of pentoxifylline in the treatment of late radiation soft tissue necrosis.
Topics: Adult; Aged; Aged, 80 and over; Female; Genitalia, Female; Humans; Male; Middle Aged; Mouth Mucosa; | 1990 |