Compounds > pentoxifylline
Page last updated: 2024-11-02

pentoxifylline and Infection

pentoxifylline has been researched along with Infection in 10 studies

Research Excerpts

ExcerptRelevanceReference
"Patients with SAH given prednisolone are at greater risk for developing serious infections and infections after treatment than patients not given prednisolone, which may offset its therapeutic benefit."9.24In Patients With Severe Alcoholic Hepatitis, Prednisolone Increases Susceptibility to Infection and Infection-Related Mortality, and Is Associated With High Circulating Levels of Bacterial DNA. ( Allison, M; Atkinson, SR; Austin, A; Forrest, EH; Gleeson, D; Knapp, S; Masson, S; Maurice, J; McCune, A; Patch, D; Richardson, P; Ryder, SD; Thursz, MR; Vergis, N; Wright, M, 2017)
"Pentoxifylline did not improve survival in patients with alcoholic hepatitis."9.20Prednisolone or pentoxifylline for alcoholic hepatitis. ( Allison, M; Austin, A; Bowers, M; Day, CP; Downs, N; Forrest, EH; Gleeson, D; Grant, A; Hood, S; MacGilchrist, A; Masson, S; McCune, A; Mellor, J; O'Grady, J; Patch, D; Ratcliffe, I; Richardson, P; Roderick, P; Ryder, S; Stanton, L; Thursz, MR; Vergis, N; Wright, M, 2015)
"Both corticosteroid and pentoxifylline reduce short-term mortality in severe alcoholic hepatitis."9.19Pentoxifylline vs. corticosteroid to treat severe alcoholic hepatitis: a randomised, non-inferiority, open trial. ( Baik, SK; Jang, JY; Kim, DJ; Kim, HS; Kim, IH; Kim, SG; Kim, TY; Kim, YS; Lee, HJ; Lee, JS; Park, SH; Park, SY; Sohn, JH; Suh, SJ; Suk, KT; Tak, WY; Um, SH; Yim, HJ; Yoon, KT, 2014)
"Patients with SAH given prednisolone are at greater risk for developing serious infections and infections after treatment than patients not given prednisolone, which may offset its therapeutic benefit."5.24In Patients With Severe Alcoholic Hepatitis, Prednisolone Increases Susceptibility to Infection and Infection-Related Mortality, and Is Associated With High Circulating Levels of Bacterial DNA. ( Allison, M; Atkinson, SR; Austin, A; Forrest, EH; Gleeson, D; Knapp, S; Masson, S; Maurice, J; McCune, A; Patch, D; Richardson, P; Ryder, SD; Thursz, MR; Vergis, N; Wright, M, 2017)
"Pentoxifylline did not improve survival in patients with alcoholic hepatitis."5.20Prednisolone or pentoxifylline for alcoholic hepatitis. ( Allison, M; Austin, A; Bowers, M; Day, CP; Downs, N; Forrest, EH; Gleeson, D; Grant, A; Hood, S; MacGilchrist, A; Masson, S; McCune, A; Mellor, J; O'Grady, J; Patch, D; Ratcliffe, I; Richardson, P; Roderick, P; Ryder, S; Stanton, L; Thursz, MR; Vergis, N; Wright, M, 2015)
"Both corticosteroid and pentoxifylline reduce short-term mortality in severe alcoholic hepatitis."5.19Pentoxifylline vs. corticosteroid to treat severe alcoholic hepatitis: a randomised, non-inferiority, open trial. ( Baik, SK; Jang, JY; Kim, DJ; Kim, HS; Kim, IH; Kim, SG; Kim, TY; Kim, YS; Lee, HJ; Lee, JS; Park, SH; Park, SY; Sohn, JH; Suh, SJ; Suk, KT; Tak, WY; Um, SH; Yim, HJ; Yoon, KT, 2014)
"The impact of infections due to cytomegalovirus has been reduced by more effective prevention in patients who are cytomegalovirus negative and reactivation in patients who are cytomegalovirus positive."2.38Supportive care in marrow transplantation. ( Bensinger, WI, 1992)
"Peripheral neuropathy, infection, and peripheral vascular disease can produce serious problems in diabetic patients, particularly in the lower limbs."1.28Lower limb problems in diabetic patients. What are the causes? What are the remedies? ( Bell, DS, 1991)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (40.00)18.2507
2000's2 (20.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Joshi, TP1
Duvic, M1
Park, SH1
Kim, DJ1
Kim, YS1
Yim, HJ1
Tak, WY1
Lee, HJ1
Sohn, JH1
Yoon, KT1
Kim, IH1
Kim, HS1
Um, SH1
Baik, SK1
Lee, JS1
Suk, KT1
Kim, SG1
Suh, SJ1
Park, SY1
Kim, TY1
Jang, JY1
Thursz, MR2
Richardson, P2
Allison, M2
Austin, A2
Bowers, M1
Day, CP1
Downs, N1
Gleeson, D2
MacGilchrist, A1
Grant, A1
Hood, S1
Masson, S2
McCune, A2
Mellor, J1
O'Grady, J1
Patch, D2
Ratcliffe, I1
Roderick, P1
Stanton, L1
Vergis, N2
Wright, M2
Ryder, S1
Forrest, EH2
Atkinson, SR1
Knapp, S1
Maurice, J1
Ryder, SD1
Tzeng, YS1
Tang, SH1
Meng, E1
Lin, TF1
Sun, GH1
Holzheimer, RG1
Molloy, RG1
O'Riordain, DS1
Mendez, MV1
Curley, P1
Collins, K1
Nestor, M1
Saporoschetz, IB1
Mannick, JA1
Rodrick, ML1
Thiel, M1
Bardenheuer, HJ1
List, AF1
Maziarz, R1
Stiff, P1
Jansen, J1
Liesveld, J1
Andrews, F1
Schuster, M1
Wolff, S1
Litzow, M1
Karanes, C1
Dahlberg, S1
Kirkhart, B1
Bianco, JA1
Singer, JW1
Bensinger, WI1
Bell, DS1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Omega-5 Fatty Acid Supplement on Markers of Inflammation and Oxidative Stress in Patients With Severe Alcoholic Hepatitis Treated With Prednisone[NCT03732586]40 participants (Actual)Interventional2018-09-30Completed
U01 Pilot Trial of DUR-928 in Patients With Moderate and Severe Alcoholic Hepatitis[NCT03917407]Phase 243 participants (Actual)Interventional2021-06-01Completed
Digoxin In Treatment of Alcohol Associated Hepatitis (DIGIT-AlcHep)[NCT05014087]Phase 260 participants (Anticipated)Interventional2021-10-08Recruiting
Corticosteroids in Severe Alcoholic Hepatitis Patients With Early Spontaneous Improvement[NCT03160651]140 participants (Anticipated)Interventional2018-02-09Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for pentoxifylline and Infection

ArticleYear
Granuloma Annulare: An Updated Review of Epidemiology, Pathogenesis, and Treatment Options.
    American journal of clinical dermatology, 2022, Volume: 23, Issue:1

    Topics: Anti-Infective Agents; Antimalarials; Biological Therapy; Comorbidity; Dermatologic Agents; Diabetes

2022
[Drug therapy of sepsis. An indication for pentoxifylline?].
    Der Anaesthesist, 1994, Volume: 43, Issue:4

    Topics: Humans; Infections; Pentoxifylline

1994
Supportive care in marrow transplantation.
    Current opinion in oncology, 1992, Volume: 4, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Bone Marrow Purging; Bone Marrow Transplantation; Child; Graft vs Host

1992

Trials

4 trials available for pentoxifylline and Infection

ArticleYear
Pentoxifylline vs. corticosteroid to treat severe alcoholic hepatitis: a randomised, non-inferiority, open trial.
    Journal of hepatology, 2014, Volume: 61, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Drug Monitoring; Female; Gastrointestinal Hemorrhage; Hepatitis, Al

2014
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
Prednisolone or pentoxifylline for alcoholic hepatitis.
    The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17

    Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum

2015
In Patients With Severe Alcoholic Hepatitis, Prednisolone Increases Susceptibility to Infection and Infection-Related Mortality, and Is Associated With High Circulating Levels of Bacterial DNA.
    Gastroenterology, 2017, Volume: 152, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Disease Susceptibility; DNA, Bacterial; Double-Blind Method; Female; F

2017
A randomized placebo-controlled trial of lisofylline in HLA-identical, sibling-donor, allogeneic bone marrow transplant recipients. The Lisofylline Marrow Transplant Study Group.
    Bone marrow transplantation, 2000, Volume: 25, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Beha

2000

Other Studies

3 other studies available for pentoxifylline and Infection

ArticleYear
Ischemic glans penis after circumcision.
    Asian journal of andrology, 2004, Volume: 6, Issue:2

    Topics: Adult; Circumcision, Male; Humans; Infections; Ischemia; Male; Nerve Block; Penis; Pentoxifylline; V

2004
Long-term immunotherapeutic intervention with pentoxifylline in a mouse model of thermal injury and infection.
    The Journal of trauma, 1995, Volume: 38, Issue:5

    Topics: Animals; Burns; Cells, Cultured; Cytokines; Dinoprostone; Infections; Interleukin-2; Interleukin-6;

1995
Lower limb problems in diabetic patients. What are the causes? What are the remedies?
    Postgraduate medicine, 1991, Volume: 89, Issue:8

    Topics: Amputation, Surgical; Anti-Bacterial Agents; Clinical Protocols; Debridement; Diabetes Complications

1991