Page last updated: 2024-11-02

pentoxifylline and Hepato-Pulmonary Syndrome

pentoxifylline has been researched along with Hepato-Pulmonary Syndrome in 10 studies

Research Excerpts

ExcerptRelevanceReference
"To determine the effects of pentoxifylline (PTX) on clinical manifestations and evaluate arterial blood gas data in hepatopulmonary syndrome (HPS) in children."7.78Pentoxifylline in hepatopulmonary syndrome. ( Afzal Aghaei, M; Khalesi, M; Kianifar, HR; Mahmoodi, E, 2012)
"Treatment with pentoxifylline did not improve arterial oxygenation in advanced HPS, and tolerance was limited by gastrointestinal toxicity."6.73Pilot study of pentoxifylline in hepatopulmonary syndrome. ( Fallon, MB; Faulk, DK; Kawut, SM; Philips, GM; Tanikella, R, 2008)
"Treatment with pentoxifylline did not improve arterial oxygenation in advanced HPS, and tolerance was limited by gastrointestinal toxicity."2.73Pilot study of pentoxifylline in hepatopulmonary syndrome. ( Fallon, MB; Faulk, DK; Kawut, SM; Philips, GM; Tanikella, R, 2008)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (70.00)29.6817
2010's2 (20.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Bakr, AG1
El-Bahrawy, AH1
Taha, HH1
Ali, FEM1
Aljudaibi, B1
Qumosani, K1
Chandok, N1
Tanikella, R1
Philips, GM1
Faulk, DK1
Kawut, SM1
Fallon, MB3
Gupta, LB1
Kumar, A1
Jaiswal, AK1
Yusuf, J1
Mehta, V1
Tyagi, S1
Tempe, DK1
Sharma, BC1
Sarin, SK1
Zhang, J2
Luo, B2
Tang, L2
Wang, Y1
Stockard, CR1
Kadish, I1
Van Groen, T1
Grizzle, WE1
Ponnazhagan, S1
Kianifar, HR1
Khalesi, M1
Mahmoodi, E1
Afzal Aghaei, M1
Dinh-Xuan, AT1
Naeije, R1
Sztrymf, B1
Rabiller, A1
Nunes, H1
Savale, L1
Lebrec, D1
Le Pape, A1
de Montpreville, V1
Mazmanian, M1
Humbert, M1
Hervé, P1
Ling, Y1
Chacko, BK1
Patel, RP1
Pastor, CM1
Schiffer, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Open Label Single Arm Pilot Study of Pentoxifylline in Advanced Hepatopulmonary Syndrome[NCT00593658]Phase 19 participants (Actual)Interventional2004-06-30Terminated (stopped due to Poor tolerability of drug and side effects)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for pentoxifylline and Hepato-Pulmonary Syndrome

ArticleYear
The hepatopulmonary syndrome: NO way out?
    The European respiratory journal, 2004, Volume: 23, Issue:5

    Topics: Enzyme Inhibitors; Hepatopulmonary Syndrome; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxi

2004
Therapy Insight: hepatopulmonary syndrome and orthotopic liver transplantation.
    Nature clinical practice. Gastroenterology & hepatology, 2007, Volume: 4, Issue:11

    Topics: Algorithms; Animals; Diagnosis, Differential; Embolization, Therapeutic; Hepatopulmonary Syndrome; H

2007

Trials

1 trial available for pentoxifylline and Hepato-Pulmonary Syndrome

ArticleYear
Pilot study of pentoxifylline in hepatopulmonary syndrome.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2008, Volume: 14, Issue:8

    Topics: Aged; Blood Gas Analysis; Female; Hepatopulmonary Syndrome; Humans; Liver Cirrhosis; Male; Middle Ag

2008

Other Studies

7 other studies available for pentoxifylline and Hepato-Pulmonary Syndrome

ArticleYear
Diosmin enhances the anti-angiogenic activity of sildenafil and pentoxifylline against hepatopulmonary syndrome via regulation of TNF-α/VEGF, IGF-1/PI3K/AKT, and FGF-1/ANG-2 signaling pathways.
    European journal of pharmacology, 2020, Apr-15, Volume: 873

    Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Diosmin; Drug Synergism; Fibroblast Growth Factor

2020
Pentoxifylline for slow to resolve hepatopulmonary syndrome post liver transplantation: helpful or unnecessary?
    Acta gastro-enterologica Belgica, 2013, Volume: 76, Issue:1

    Topics: Adult; Combined Modality Therapy; Hepatopulmonary Syndrome; Humans; Liver Transplantation; Male; Mid

2013
Pentoxifylline therapy for hepatopulmonary syndrome: a pilot study.
    Archives of internal medicine, 2008, Sep-08, Volume: 168, Issue:16

    Topics: Adolescent; Adult; Animals; Blood Gas Analysis; Female; Hepatopulmonary Syndrome; Humans; Male; Midd

2008
Pulmonary angiogenesis in a rat model of hepatopulmonary syndrome.
    Gastroenterology, 2009, Volume: 136, Issue:3

    Topics: Angiostatins; Animals; Common Bile Duct; Disease Models, Animal; Endostatins; Hepatopulmonary Syndro

2009
Pentoxifylline in hepatopulmonary syndrome.
    World journal of gastroenterology, 2012, Sep-21, Volume: 18, Issue:35

    Topics: Adolescent; Blood Gas Analysis; Child; Child, Preschool; Female; Hepatopulmonary Syndrome; Humans; M

2012
Prevention of hepatopulmonary syndrome and hyperdynamic state by pentoxifylline in cirrhotic rats.
    The European respiratory journal, 2004, Volume: 23, Issue:5

    Topics: Animals; Aorta; Bacterial Translocation; Blood Cells; Blood Circulation; Enzyme Inhibitors; Hemodyna

2004
Pentoxifylline attenuation of experimental hepatopulmonary syndrome.
    Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 102, Issue:3

    Topics: Animals; Cells, Cultured; Common Bile Duct; Cyclic AMP; Endothelial Cells; Endothelium, Vascular; He

2007