pentoxifylline has been researched along with Hemorrhagic Shock in 39 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Data presented showed that pentoxifylline attenuates microcirculatory disturbances at the mesenteric bed with significant minimization of lung inflammation after a double-injury model of hemorrhagic shock and reperfusion followed by sepsis." | 7.81 | Pentoxifylline attenuates leukocyte-endothelial interactions in a two-hit model of shock and sepsis. ( Aikawa, P; Correia, CJ; Cruz, JW; Cruz, RJ; Mauad, T; Nakagawa, NK; Rocha-e-Silva, M; Sannomiya, P; Zhang, H, 2015) |
| " Resuscitation with hypertonic saline and pentoxifylline (HSPTX) has been shown to attenuate hemorrhagic shock-induced injury when compared with RL." | 7.74 | Hypertonic saline and pentoxifylline reduces hemorrhagic shock resuscitation-induced pulmonary inflammation through attenuation of neutrophil degranulation and proinflammatory mediator synthesis. ( Coimbra, R; de Campos, T; Deree, J; Hoyt, DB; Lamon, B; Leedom, A; Martins, JO; Putnam, J; Wolf, P, 2007) |
| " We hypothesized that the anti-inflammatory agent pentoxifylline (PTX) attenuates postresuscitative lung injury through modulation of transcription factors after hemorrhagic shock." | 7.74 | Pentoxifylline attenuates lung injury and modulates transcription factor activity in hemorrhagic shock. ( Coimbra, R; de Campos, T; Deree, J; Loomis, WH; Martins, J; Putnam, JG; Wolf, P, 2007) |
| "This study shows that a novel route (via the pulmonary circulation) used to administer pentoxifylline after hemorrhagic shock leads to superior cardiac performance in comparison with administration via lactated Ringer's solution or i." | 7.72 | Intraarterial pulmonary pentoxifylline improves cardiac performance and oxygen utilization after hemorrhagic shock: a novel resuscitation strategy. ( Coimbra, R; Razuk-Filho, A; Rocha-E-Silva, M; Yada-Langui, MM, 2004) |
| "Previous reports have shown beneficial effects of pentoxifylline (PTX) and hypertonic saline (HS) in the treatment of hemorrhagic shock." | 7.70 | Hypertonic saline and pentoxifylline prevent lung injury and bacterial translocation after hemorrhagic shock. ( Coimbra, R; Correia, N; Garcia, C; Lancellotti, C; Mimica, I; Rocha e Silva, M; Yada-Langui, MM, 2000) |
| "Dextran and pentoxifylline have been shown to prevent leukocyte-endothelium adherence encountered after hemorrhagic shock." | 7.70 | Effects of dextran and pentoxifylline on hemorrhagic shock-induced P-selectin expression. ( Akgür, FM; Brown, MF; Granger, DN; McDonald, JC; Zibari, GB, 1999) |
| "To evaluate the effects of pentoxifylline (PF) administration on liver, gut, and peripheral oxygenation during crystalloid resuscitation of hemorrhagic shock." | 7.70 | Hepatosplanchnic and peripheral tissue oxygenation during treatment of hemorrhagic shock: the effects of pentoxifylline administration. ( Härkönen, M; Höckerstedt, K; Mäkisalo, H; Mildh, L; Nordin, A, 1998) |
| "To evaluate the effect of pentoxifylline on altered hepatocyte calcium regulation and hepatocyte oxidant injury after hemorrhagic shock." | 7.70 | Pentoxifylline prevention of altered hepatocyte calcium regulation during hemorrhagic shock/resuscitation. ( Larsen, R; Pizanis, A; Rose, S; Silomon, M, 1998) |
| "The aim of this study was to evaluate the effects of two xanthine derivates, pentoxifylline (PTX) and its more metabolically stable analogue, albifylline (HWA 138), on hepatic sinusoidal perfusion and leukocyte endothelial interactions in the liver after hemorrhagic shock." | 7.69 | Influence of pentoxifylline and albifylline on liver microcirculation and leukocyte adhesion after hemorrhagic shock in the rat. ( Bauer, M; Herzog, C; Maier, M; Marzi, I, 1996) |
| "Lisofylline improves survival in this model of hemorrhagic shock." | 7.69 | Lisofylline decreases white cell adhesiveness and improves survival after experimental hemorrhagic shock. ( Aswani, S; Daughters, K; Rice, G; Waxman, K, 1996) |
| " The number of activated circulating PMNs as measured by the reduction of nitroblue tetrazolium (NBT-positive PMNs) were shown to be closely associated with the trend towards irreversibility in hemorrhagic shock." | 7.68 | Pentoxifylline pretreatment decreases the pool of circulating activated neutrophils, in-vivo adhesion to endothelium, and improves survival from hemorrhagic shock. ( Barroso-Aranda, J; Schmid-Schönbein, GW, 1990) |
| "After determining that hepatic blood flow remains impaired after resuscitation from hemorrhagic shock, we used the angiotensin II receptor antagonist saralasin and pentoxifylline to investigate their respective effects on hepatic blood flow responses after resuscitation from hemorrhagic shock." | 7.68 | Pentoxifylline but not saralasin restores hepatic blood flow after resuscitation from hemorrhagic shock. ( Cryer, HG; Flynn, WJ; Garrison, RN, 1991) |
| "Pentoxifylline improves survival in animal models of hemorrhagic shock." | 7.68 | Pentoxifylline in resuscitation of experimental hemorrhagic shock. ( Clark, L; Parazin, S; Soliman, MH; Waxman, K, 1991) |
| "In this acute, nonresuscitated, canine hemorrhagic shock model, pentoxifylline did not act as a vasodilator, or have any significant effect on HR, cardiac output, oxygen transport, or lactic acidosis." | 7.68 | Effects of pentoxifylline on hemodynamics, oxygen transport, and tissue metabolism in experimental, severe hemorrhagic shock. ( Amin, D; Benjamin, E; Fischer, E; Iberti, TJ; Jacobs, E; Klapholtz, A; Oropello, JM, 1991) |
| "Pentoxifylline (PTX) and superoxide dismutase (SOD) have each proven effective in improving survival when administered during resuscitation in animal models of hemorrhagic shock." | 7.68 | Pentoxifylline alone versus pentoxifylline combined with superoxide dismutase prolongs survival in a rat hemorrhagic shock model. ( Dinh, L; Eloi, L; Scannell, G; Tominaga, GT; Waxman, K, 1993) |
| "This randomized and blinded study was performed to determine whether pentoxifylline significantly improves tissue oxygenation after hemorrhagic shock." | 7.67 | Pentoxifylline improves tissue oxygenation after hemorrhagic shock. ( Holness, R; Oslund, S; Pinderski, L; Soliman, MH; Tominaga, G; Waxman, K, 1987) |
| "The mean lung injury score was 1." | 5.38 | The effectiveness of hypertonic saline and pentoxifylline (HTS-PTX) resuscitation in haemorrhagic shock and sepsis tissue injury: comparison with LR, HES, and LR-PTX treatments. ( Kim, HJ; Lee, KH, 2012) |
| "In a rat model of hemorrhagic shock, resuscitation was conducted with RL (32 mL/kg; n = 7) or HSPTX (4 mL/kg 7." | 5.34 | Hypertonic saline and pentoxifylline attenuates gut injury after hemorrhagic shock: the kinder, gentler resuscitation. ( Coimbra, R; de Campos, T; Deree, J; Hoyt, DB; Loomis, WH; Shenvi, E, 2007) |
| "Pentoxifylline treatment just after shed blood transfusion significantly attenuated this phenomenon." | 5.31 | The effects of pentoxifylline treatment on bacterial translocation after hemorrhagic shock in rats. ( Arpacik, M; Bakici, MZ; Elagöz, S; Köylüoglu, G, 2001) |
| "Pentoxifylline promotes gut ketogenesis following trauma-hemorrhage and resuscitation." | 5.30 | Pentoxifylline increases gut ketogenesis following trauma and hemorrhagic shock. ( Chaudry, IH; Wang, P; Wang, W, 1998) |
| "Pentoxifylline is an agent which improves microcirculatory blood flow, but its use as therapy for shock has not been reported." | 5.28 | Pentoxifylline improves survival following hemorrhagic shock. ( Coccia, MT; Pinderski, L; Soliman, MH; Tominaga, G; Waxman, K, 1989) |
| "Data presented showed that pentoxifylline attenuates microcirculatory disturbances at the mesenteric bed with significant minimization of lung inflammation after a double-injury model of hemorrhagic shock and reperfusion followed by sepsis." | 3.81 | Pentoxifylline attenuates leukocyte-endothelial interactions in a two-hit model of shock and sepsis. ( Aikawa, P; Correia, CJ; Cruz, JW; Cruz, RJ; Mauad, T; Nakagawa, NK; Rocha-e-Silva, M; Sannomiya, P; Zhang, H, 2015) |
| "To assess the effects of hypertonic saline and pentoxifylline on the inflammatory response and oxidative stress, Wistar rats underwent a laparotomy loop intestinal obstruction and ischemia." | 3.80 | Inflammatory activity modulation by hypertonic saline and pentoxifylline in a rat model of strangulated closed loop small bowel obstruction. ( da Costa, VA; de Victo, NC; Ferreira, TC; Marques, GM; Montero, EF; Rasslan, R; Rasslan, S; Utiyama, EM, 2014) |
| "Combining the hemodynamic and immune benefits of hypertonic saline with the anti-inflammatory effects of the phosphodiesterase inhibitor pentoxifylline (HSPTX) as a hemorrhagic shock resuscitation strategy reduces lung injury when compared with the effects of Ringer's lactate (RL)." | 3.76 | A novel fluid resuscitation strategy modulates pulmonary transcription factor activation in a murine model of hemorrhagic shock. ( Campos, Td; Coimbra, R; Costantini, TW; Deree, J; Martins, JO; Putnam, JG, 2010) |
| " We hypothesized that the anti-inflammatory agent pentoxifylline (PTX) attenuates postresuscitative lung injury through modulation of transcription factors after hemorrhagic shock." | 3.74 | Pentoxifylline attenuates lung injury and modulates transcription factor activity in hemorrhagic shock. ( Coimbra, R; de Campos, T; Deree, J; Loomis, WH; Martins, J; Putnam, JG; Wolf, P, 2007) |
| " Resuscitation with hypertonic saline and pentoxifylline (HSPTX) has been shown to attenuate hemorrhagic shock-induced injury when compared with RL." | 3.74 | Hypertonic saline and pentoxifylline reduces hemorrhagic shock resuscitation-induced pulmonary inflammation through attenuation of neutrophil degranulation and proinflammatory mediator synthesis. ( Coimbra, R; de Campos, T; Deree, J; Hoyt, DB; Lamon, B; Leedom, A; Martins, JO; Putnam, J; Wolf, P, 2007) |
| " Pentoxifylline (PTX) has beneficial effects when administrated after hemorrhagic shock." | 3.73 | The synergistic effects of pentoxifylline on systemic and regional perfusion after hemorrhage and hypertonic resuscitation. ( Cruz, RJ; de Figueiredo, LF; Rocha e Silva, M; Sinosaki, S; Yada-Langui, MM, 2006) |
| "We sought to determine whether treatment with lisofylline (LSF) preserves intestinal barrier function in rats subjected to hemorrhagic shock and resuscitation (HS/R)." | 3.70 | Lisofylline ameliorates intestinal and hepatic injury induced by hemorrhage and resuscitation in rats. ( Fink, MP; Menconi, MJ; Wattanasirichaigoon, S, 2000) |
| "Previous reports have shown beneficial effects of pentoxifylline (PTX) and hypertonic saline (HS) in the treatment of hemorrhagic shock." | 3.70 | Hypertonic saline and pentoxifylline prevent lung injury and bacterial translocation after hemorrhagic shock. ( Coimbra, R; Correia, N; Garcia, C; Lancellotti, C; Mimica, I; Rocha e Silva, M; Yada-Langui, MM, 2000) |
| "The aim of this study was to evaluate the effects of two xanthine derivates, pentoxifylline (PTX) and its more metabolically stable analogue, albifylline (HWA 138), on hepatic sinusoidal perfusion and leukocyte endothelial interactions in the liver after hemorrhagic shock." | 3.69 | Influence of pentoxifylline and albifylline on liver microcirculation and leukocyte adhesion after hemorrhagic shock in the rat. ( Bauer, M; Herzog, C; Maier, M; Marzi, I, 1996) |
| "Lisofylline improves survival in this model of hemorrhagic shock." | 3.69 | Lisofylline decreases white cell adhesiveness and improves survival after experimental hemorrhagic shock. ( Aswani, S; Daughters, K; Rice, G; Waxman, K, 1996) |
| "In this acute, nonresuscitated, canine hemorrhagic shock model, pentoxifylline did not act as a vasodilator, or have any significant effect on HR, cardiac output, oxygen transport, or lactic acidosis." | 3.68 | Effects of pentoxifylline on hemodynamics, oxygen transport, and tissue metabolism in experimental, severe hemorrhagic shock. ( Amin, D; Benjamin, E; Fischer, E; Iberti, TJ; Jacobs, E; Klapholtz, A; Oropello, JM, 1991) |
| "After determining that hepatic blood flow remains impaired after resuscitation from hemorrhagic shock, we used the angiotensin II receptor antagonist saralasin and pentoxifylline to investigate their respective effects on hepatic blood flow responses after resuscitation from hemorrhagic shock." | 3.68 | Pentoxifylline but not saralasin restores hepatic blood flow after resuscitation from hemorrhagic shock. ( Cryer, HG; Flynn, WJ; Garrison, RN, 1991) |
| " The number of activated circulating PMNs as measured by the reduction of nitroblue tetrazolium (NBT-positive PMNs) were shown to be closely associated with the trend towards irreversibility in hemorrhagic shock." | 3.68 | Pentoxifylline pretreatment decreases the pool of circulating activated neutrophils, in-vivo adhesion to endothelium, and improves survival from hemorrhagic shock. ( Barroso-Aranda, J; Schmid-Schönbein, GW, 1990) |
| "This randomized and blinded study was performed to determine whether pentoxifylline significantly improves tissue oxygenation after hemorrhagic shock." | 3.67 | Pentoxifylline improves tissue oxygenation after hemorrhagic shock. ( Holness, R; Oslund, S; Pinderski, L; Soliman, MH; Tominaga, G; Waxman, K, 1987) |
| "The mean lung injury score was 1." | 1.38 | The effectiveness of hypertonic saline and pentoxifylline (HTS-PTX) resuscitation in haemorrhagic shock and sepsis tissue injury: comparison with LR, HES, and LR-PTX treatments. ( Kim, HJ; Lee, KH, 2012) |
| "In a rat model of hemorrhagic shock, resuscitation was conducted with RL (32 mL/kg; n = 7) or HSPTX (4 mL/kg 7." | 1.34 | Hypertonic saline and pentoxifylline attenuates gut injury after hemorrhagic shock: the kinder, gentler resuscitation. ( Coimbra, R; de Campos, T; Deree, J; Hoyt, DB; Loomis, WH; Shenvi, E, 2007) |
| "Pentoxifylline treatment just after shed blood transfusion significantly attenuated this phenomenon." | 1.31 | The effects of pentoxifylline treatment on bacterial translocation after hemorrhagic shock in rats. ( Arpacik, M; Bakici, MZ; Elagöz, S; Köylüoglu, G, 2001) |
| "Pentoxifylline promotes gut ketogenesis following trauma-hemorrhage and resuscitation." | 1.30 | Pentoxifylline increases gut ketogenesis following trauma and hemorrhagic shock. ( Chaudry, IH; Wang, P; Wang, W, 1998) |
| "Pentoxifylline is an agent which improves microcirculatory blood flow, but its use as therapy for shock has not been reported." | 1.28 | Pentoxifylline improves survival following hemorrhagic shock. ( Coccia, MT; Pinderski, L; Soliman, MH; Tominaga, G; Waxman, K, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (7.69) | 18.7374 |
| 1990's | 19 (48.72) | 18.2507 |
| 2000's | 13 (33.33) | 29.6817 |
| 2010's | 4 (10.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rasslan, R | 1 |
| Utiyama, EM | 1 |
| Marques, GM | 1 |
| Ferreira, TC | 1 |
| da Costa, VA | 1 |
| de Victo, NC | 1 |
| Rasslan, S | 1 |
| Montero, EF | 1 |
| Nakagawa, NK | 1 |
| Cruz, RJ | 2 |
| Aikawa, P | 1 |
| Correia, CJ | 1 |
| Cruz, JW | 1 |
| Mauad, T | 1 |
| Zhang, H | 1 |
| Rocha-e-Silva, M | 2 |
| Sannomiya, P | 2 |
| Costantini, TW | 1 |
| Deree, J | 6 |
| Martins, JO | 2 |
| Putnam, JG | 2 |
| Campos, Td | 1 |
| Coimbra, R | 11 |
| Kim, HJ | 1 |
| Lee, KH | 1 |
| Melbostad, H | 3 |
| Hoyt, DB | 5 |
| Razuk-Filho, A | 1 |
| Yada-Langui, MM | 4 |
| Anjos-Valotta, EA | 1 |
| Rocha e Silva, M | 3 |
| Loomis, W | 2 |
| Tobar, M | 1 |
| Porcides, RD | 1 |
| Lall, R | 2 |
| Holbrook, T | 1 |
| Porcides, R | 1 |
| Wolf, P | 4 |
| de Figueiredo, LF | 1 |
| Sinosaki, S | 1 |
| Leedom, A | 1 |
| Lamon, B | 1 |
| Putnam, J | 1 |
| de Campos, T | 3 |
| Shenvi, E | 1 |
| Loomis, WH | 3 |
| Martins, J | 1 |
| Kirpatovskiĭ, VI | 1 |
| Onishchenko, NA | 1 |
| Lubiako, AA | 1 |
| Danilov, MA | 1 |
| Bogoiavlenskaia, TA | 1 |
| Wang, P | 4 |
| Ba, ZF | 1 |
| Stepp, KJ | 1 |
| Chaudry, IH | 4 |
| Waxman, K | 6 |
| Eloi, L | 1 |
| Dinh, L | 1 |
| Scannell, G | 1 |
| Tominaga, GT | 1 |
| Marzi, I | 1 |
| Maier, M | 1 |
| Herzog, C | 1 |
| Bauer, M | 1 |
| Daughters, K | 1 |
| Aswani, S | 1 |
| Rice, G | 1 |
| Robinson, DA | 1 |
| Wang, W | 1 |
| Hotchkiss, RS | 1 |
| Karl, IE | 1 |
| Silomon, M | 1 |
| Pizanis, A | 1 |
| Larsen, R | 1 |
| Rose, S | 1 |
| Nordin, A | 1 |
| Mildh, L | 1 |
| Mäkisalo, H | 1 |
| Härkönen, M | 1 |
| Höckerstedt, K | 1 |
| Luft, FC | 1 |
| Jarrar, D | 1 |
| Akgür, FM | 1 |
| Zibari, GB | 1 |
| McDonald, JC | 1 |
| Granger, DN | 1 |
| Brown, MF | 1 |
| Wattanasirichaigoon, S | 1 |
| Menconi, MJ | 1 |
| Fink, MP | 1 |
| Lancellotti, C | 1 |
| Mimica, I | 1 |
| Garcia, C | 1 |
| Correia, N | 1 |
| Köylüoglu, G | 1 |
| Bakici, MZ | 1 |
| Elagöz, S | 1 |
| Arpacik, M | 1 |
| Flynn, WJ | 2 |
| Cryer, HG | 2 |
| Garrison, RN | 2 |
| Haupt, MT | 1 |
| Oropello, JM | 1 |
| Amin, D | 1 |
| Klapholtz, A | 1 |
| Benjamin, E | 1 |
| Fischer, E | 1 |
| Jacobs, E | 1 |
| Iberti, TJ | 1 |
| Clark, L | 1 |
| Soliman, MH | 3 |
| Parazin, S | 1 |
| Barroso-Aranda, J | 1 |
| Schmid-Schönbein, GW | 1 |
| Coccia, MT | 1 |
| Tominaga, G | 2 |
| Pinderski, L | 2 |
| Holness, R | 1 |
| Oslund, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| HYPERTONIC SALINE COATED FACE MASK FOR REDUCING RESPIRATORY SYMPTOM SEVERITY IN PATIENTS WITH COVID-19[NCT04465604] | 50 participants (Anticipated) | Interventional | 2021-02-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for pentoxifylline and Hemorrhagic Shock
| Article | Year |
|---|---|
Effects of phosphodiesterase inhibition on the inflammatory response after shock: role of pentoxifylline.
Topics: Adjuvants, Immunologic; Animals; Cytokines; Humans; Isotonic Solutions; Neutrophil Activation; Neutr | 2004 |
Organ dysfunction following hemorrhage and sepsis: mechanisms and therapeutic approaches (Review).
Topics: Adenosine Triphosphate; Animals; Coloring Agents; Critical Care; Cytokines; Diltiazem; Disease Model | 1999 |
37 other studies available for pentoxifylline and Hemorrhagic Shock
| Article | Year |
|---|---|
Inflammatory activity modulation by hypertonic saline and pentoxifylline in a rat model of strangulated closed loop small bowel obstruction.
Topics: Animals; Cytokines; Drug Evaluation, Preclinical; Fluid Therapy; Interleukin-6; Intestinal Obstructi | 2014 |
Pentoxifylline attenuates leukocyte-endothelial interactions in a two-hit model of shock and sepsis.
Topics: Animals; Cecum; Cell Communication; Disease Models, Animal; Endothelial Cells; Free Radical Scavenge | 2015 |
A novel fluid resuscitation strategy modulates pulmonary transcription factor activation in a murine model of hemorrhagic shock.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Inflammation Mediators; Lung; Male; NF-ka | 2010 |
The effectiveness of hypertonic saline and pentoxifylline (HTS-PTX) resuscitation in haemorrhagic shock and sepsis tissue injury: comparison with LR, HES, and LR-PTX treatments.
Topics: Animals; Disease Models, Animal; Hydroxyethyl Starch Derivatives; Interleukin-6; Isotonic Solutions; | 2012 |
Intraarterial pulmonary pentoxifylline improves cardiac performance and oxygen utilization after hemorrhagic shock: a novel resuscitation strategy.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiopulmonary Resuscitation; Dogs; Heart; Heart Rate; Hem | 2004 |
Resuscitation affects microcirculatory polymorphonuclear leukocyte behavior after hemorrhagic shock: role of hypertonic saline and pentoxifylline.
Topics: Animals; Disease Models, Animal; Male; Microcirculation; Neutrophils; Pentoxifylline; Rats; Rats, Wi | 2004 |
Role of hypertonic saline and pentoxifylline on neutrophil activation and tumor necrosis factor-alpha synthesis: a novel resuscitation strategy.
Topics: CD11b Antigen; Drug Therapy, Combination; Flow Cytometry; Humans; In Vitro Techniques; Lipopolysacch | 2005 |
HSPTX protects against hemorrhagic shock resuscitation-induced tissue injury: an attractive alternative to Ringer's lactate.
Topics: Animals; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Hematologic Agents; Ileu | 2006 |
The synergistic effects of pentoxifylline on systemic and regional perfusion after hemorrhage and hypertonic resuscitation.
Topics: Animals; Blood Pressure; Blood Volume; Dogs; Fluid Therapy; Isotonic Solutions; Male; Pentoxifylline | 2006 |
Hypertonic saline and pentoxifylline reduces hemorrhagic shock resuscitation-induced pulmonary inflammation through attenuation of neutrophil degranulation and proinflammatory mediator synthesis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Degranulation; Enzyme-Linked Immunosorbent Assay; Fluid | 2007 |
Hypertonic saline and pentoxifylline attenuates gut injury after hemorrhagic shock: the kinder, gentler resuscitation.
Topics: Abdominal Injuries; Animals; Cytokines; Down-Regulation; Drug Combinations; Fluid Therapy; Heme Oxyg | 2007 |
Pentoxifylline attenuates lung injury and modulates transcription factor activity in hemorrhagic shock.
Topics: Animals; Anti-Inflammatory Agents; Chemokine CXCL1; Disease Models, Animal; Heme Oxygenase-1; Isoton | 2007 |
Hepatic transcription factor activation and proinflammatory mediator production is attenuated by hypertonic saline and pentoxifylline resuscitation after hemorrhagic shock.
Topics: Animals; Cytokines; Enzyme Activation; Liver; Male; NF-kappa B; Nitric Oxide Synthase Type II; Pento | 2008 |
[Pharmacological protection of the kidneys from ischemic damage. The effectiveness of anti-ischemia protection of the kidneys in simulating the terminal state in the donors].
Topics: Animals; Death; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Humans; Hypotension; Isc | 1982 |
Pentoxifylline attenuates the depressed endothelial cell function and vascular muscle contractility following trauma and hemorrhagic shock.
Topics: Animals; Endothelium, Vascular; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; No | 1995 |
Pentoxifylline alone versus pentoxifylline combined with superoxide dismutase prolongs survival in a rat hemorrhagic shock model.
Topics: Animals; Drug Therapy, Combination; Male; Pentoxifylline; Rats; Rats, Sprague-Dawley; Resuscitation; | 1993 |
Influence of pentoxifylline and albifylline on liver microcirculation and leukocyte adhesion after hemorrhagic shock in the rat.
Topics: Animals; Cell Adhesion Molecules; Disease Models, Animal; Female; Liver Circulation; Pentoxifylline; | 1996 |
Lisofylline decreases white cell adhesiveness and improves survival after experimental hemorrhagic shock.
Topics: Adjuvants, Immunologic; Animals; Blood Pressure; Cell Adhesion; Leukocytes; Male; Pentoxifylline; Pl | 1996 |
Pentoxifylline restores the depressed cardiac performance after trauma-hemorrhage and resuscitation.
Topics: Animals; Blood Pressure; Heart Rate; Male; Pentoxifylline; Rats; Rats, Sprague-Dawley; Resuscitation | 1996 |
Pentoxifylline preserves intestinal function (and more) following shock.
Topics: Animals; Disease Models, Animal; Intestines; Pentoxifylline; Phosphodiesterase Inhibitors; Resuscita | 1998 |
Pentoxifylline increases gut ketogenesis following trauma and hemorrhagic shock.
Topics: 3-Hydroxybutyric Acid; Acyl-CoA Dehydrogenase; Animal Feed; Animals; Disease Models, Animal; Fatty A | 1998 |
Pentoxifylline and modulation of the inflammatory response.
Topics: Animals; Anti-Inflammatory Agents; Calcium; Cytokines; Liver; Pentoxifylline; Rats; Reperfusion Inju | 1998 |
Pentoxifylline prevention of altered hepatocyte calcium regulation during hemorrhagic shock/resuscitation.
Topics: Animals; Anti-Inflammatory Agents; Calcium; Epinephrine; Glutathione; Hemodynamics; Lipid Peroxidati | 1998 |
Hepatosplanchnic and peripheral tissue oxygenation during treatment of hemorrhagic shock: the effects of pentoxifylline administration.
Topics: Animals; Hemodynamics; Oxygen Consumption; Pentoxifylline; Shock, Hemorrhagic; Swine; Vasodilator Ag | 1998 |
A shocking state of affairs.
Topics: Endotoxins; Humans; Multiple Organ Failure; Pentoxifylline; Shock, Hemorrhagic; Tumor Necrosis Facto | 1999 |
Effects of dextran and pentoxifylline on hemorrhagic shock-induced P-selectin expression.
Topics: Animals; Dextrans; Mice; Mice, Inbred C57BL; P-Selectin; Pentoxifylline; Rats; Resuscitation; Shock, | 1999 |
Lisofylline ameliorates intestinal and hepatic injury induced by hemorrhage and resuscitation in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity; Cell Membrane Permeability; E | 2000 |
Hypertonic saline and pentoxifylline prevent lung injury and bacterial translocation after hemorrhagic shock.
Topics: Animals; Bacteria; Lung; Lung Injury; Male; Pentoxifylline; Rats; Rats, Wistar; Saline Solution, Hyp | 2000 |
The effects of pentoxifylline treatment on bacterial translocation after hemorrhagic shock in rats.
Topics: Animals; Bacterial Infections; Bacterial Translocation; Blood; Blood Transfusion, Autologous; Cecum; | 2001 |
Pentoxifylline restores intestinal microvascular blood flow during resuscitated hemorrhagic shock.
Topics: Analysis of Variance; Animals; Blood Flow Velocity; Intestines; Isotonic Solutions; Male; Microcircu | 1991 |
Pentoxifylline and the microcirculation in hemorrhagic shock.
Topics: Blood Cells; Humans; Microcirculation; Pentoxifylline; Shock, Hemorrhagic | 1991 |
Effects of pentoxifylline on hemodynamics, oxygen transport, and tissue metabolism in experimental, severe hemorrhagic shock.
Topics: Animals; Disease Models, Animal; Dogs; Double-Blind Method; Drug Evaluation, Preclinical; Hemodynami | 1991 |
Pentoxifylline in resuscitation of experimental hemorrhagic shock.
Topics: Animals; Blood Pressure; Cardiac Output; Cell Adhesion; Neutrophils; Oxygen; Pentoxifylline; Rats; R | 1991 |
Pentoxifylline but not saralasin restores hepatic blood flow after resuscitation from hemorrhagic shock.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiac Output; Liver Circulation; Pentoxifylline; Rats; Re | 1991 |
Pentoxifylline pretreatment decreases the pool of circulating activated neutrophils, in-vivo adhesion to endothelium, and improves survival from hemorrhagic shock.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Cell Adhesion; Heart Rate; Leukocyte Count; Male; Neut | 1990 |
Pentoxifylline improves survival following hemorrhagic shock.
Topics: Animals; Fluid Therapy; Male; Pentoxifylline; Rats; Rats, Inbred Strains; Shock, Hemorrhagic; Theobr | 1989 |
Pentoxifylline improves tissue oxygenation after hemorrhagic shock.
Topics: Animals; Double-Blind Method; Liver; Oxygen Consumption; Pentoxifylline; Random Allocation; Rats; Ra | 1987 |