pentoxifylline has been researched along with Hemorrhage in 15 studies
Hemorrhage: Bleeding or escape of blood from a vessel.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of phosphodiesterase inhibitor, pentoxifylline, in the prevention of cyclophosphamide-induced hemorrhagic cystitis was evaluated in a rat model." | 7.79 | Uroprotective effect of pentoxifylline in cyclophosphamide-induced hemorrhagic cystitis in rats. ( Abo-Salem, OM, 2013) |
| "Hemorrhagic cystitis (HC) is a limiting side effect of chemotherapy with ifosfamide (IFS)." | 7.74 | Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats. ( Almeida, PR; Baltazar, F; Brito, GA; Ferreira, FV; Macedo, FY; Ribeiro, RA; Schmitt, FC; Távora, F, 2008) |
| "The aim of this study was to investigate whether the methylxanthine-derivative pentoxifylline (PTX) affects bacterial clearance of the organism in states of hemorrhage and endotoxemia." | 7.70 | Pentoxifylline improves bacterial clearance during hemorrhage and endotoxemia. ( Heller, A; Heller, S; Koch, T; Urbaschek, R; Weber, K, 1999) |
| "Although pentoxifylline produces various beneficial effects in a preheparinized model of hemorrhagic shock, it was unknown whether this agent restores the depressed cardiac output (CO) and tissue perfusion in a nonheparinized model of trauma-hemorrhage and resuscitation and, if so, whether it decreases the susceptibility to sepsis after hemorrhage." | 7.68 | Pentoxifylline restores cardiac output and tissue perfusion after trauma-hemorrhage and decreases susceptibility to sepsis. ( Ba, ZF; Chaudry, IH; Tait, SM; Wang, P; Zhou, M, 1993) |
| "The effect of pentoxifylline, a phosphodiesterase inhibitor, was investigated on the development of cerebral malaria in Plasmodium berghei K 173 infected C57/B16 mice." | 7.68 | Selective damage of hippocampal neurons in murine cerebral malaria prevented by pentoxifylline. ( Bienzle, U; Eling, WM; Kremsner, PG; Neifer, S; Stoltenburg-Didinger, G, 1993) |
| "The purpose of this study was to determine whether pentoxifylline administration restores the depressed hepatocellular function after trauma hemorrhage and crystalloid resuscitation and, if so, whether this is the result of the down-regulation of inflammatory cytokines, tumor necrosis factor (TNF) and interleukin-6 (IL-6)." | 7.68 | Mechanism of the beneficial effects of pentoxifylline on hepatocellular function after trauma hemorrhage and resuscitation. ( Ayala, A; Ba, ZF; Chaudry, IH; Morrison, MH; Wang, P, 1992) |
| "Cilostazol has been associated with spontaneous reports of cardiovascular adverse events and serious bleeding." | 3.88 | Safety of cilostazol in peripheral artery disease: a cohort from a primary healthcare electronic database. ( Alzamora, M; Forés, R; Giner-Soriano, M; Heras, A; Marsal, JR; Morros, R; Pera, G; Real, J; Ribes, E; Serna, MC, 2018) |
| "The role of phosphodiesterase inhibitor, pentoxifylline, in the prevention of cyclophosphamide-induced hemorrhagic cystitis was evaluated in a rat model." | 3.79 | Uroprotective effect of pentoxifylline in cyclophosphamide-induced hemorrhagic cystitis in rats. ( Abo-Salem, OM, 2013) |
| "Hemorrhagic cystitis (HC) is a limiting side effect of chemotherapy with ifosfamide (IFS)." | 3.74 | Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats. ( Almeida, PR; Baltazar, F; Brito, GA; Ferreira, FV; Macedo, FY; Ribeiro, RA; Schmitt, FC; Távora, F, 2008) |
| "The aim of this study was to investigate whether the methylxanthine-derivative pentoxifylline (PTX) affects bacterial clearance of the organism in states of hemorrhage and endotoxemia." | 3.70 | Pentoxifylline improves bacterial clearance during hemorrhage and endotoxemia. ( Heller, A; Heller, S; Koch, T; Urbaschek, R; Weber, K, 1999) |
| "Although pentoxifylline produces various beneficial effects in a preheparinized model of hemorrhagic shock, it was unknown whether this agent restores the depressed cardiac output (CO) and tissue perfusion in a nonheparinized model of trauma-hemorrhage and resuscitation and, if so, whether it decreases the susceptibility to sepsis after hemorrhage." | 3.68 | Pentoxifylline restores cardiac output and tissue perfusion after trauma-hemorrhage and decreases susceptibility to sepsis. ( Ba, ZF; Chaudry, IH; Tait, SM; Wang, P; Zhou, M, 1993) |
| "The effect of pentoxifylline, a phosphodiesterase inhibitor, was investigated on the development of cerebral malaria in Plasmodium berghei K 173 infected C57/B16 mice." | 3.68 | Selective damage of hippocampal neurons in murine cerebral malaria prevented by pentoxifylline. ( Bienzle, U; Eling, WM; Kremsner, PG; Neifer, S; Stoltenburg-Didinger, G, 1993) |
| "The purpose of this study was to determine whether pentoxifylline administration restores the depressed hepatocellular function after trauma hemorrhage and crystalloid resuscitation and, if so, whether this is the result of the down-regulation of inflammatory cytokines, tumor necrosis factor (TNF) and interleukin-6 (IL-6)." | 3.68 | Mechanism of the beneficial effects of pentoxifylline on hepatocellular function after trauma hemorrhage and resuscitation. ( Ayala, A; Ba, ZF; Chaudry, IH; Morrison, MH; Wang, P, 1992) |
| "Oral mucositis is a frequent side-effect of cancer therapy." | 1.33 | Effects of the tumour necrosis factor-alpha inhibitors pentoxifylline and thalidomide in short-term experimental oral mucositis in hamsters. ( Augusto, RF; Brito, GA; Cunha, FQ; Falcão, BA; Leitão, BT; Lima, V; Rebouças, CG; Ribeiro, RA; Souza, ML, 2005) |
| "Pentoxifylline is a phosphodiesterase inhibitor, known to suppress tumour necrosis factor-alpha production and improve cardiopulmonary parameters and survival in animal models of sepsis." | 1.31 | Pentoxifylline fails to improve organ dysfunction and survival when used in the resuscitation of a porcine model of haemorrhage and abdominal sepsis. ( Brown, D; Kenward, CE; Parker, SJ; Watkins, PE, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (60.00) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Real, J | 1 |
| Serna, MC | 1 |
| Giner-Soriano, M | 1 |
| Forés, R | 1 |
| Pera, G | 1 |
| Ribes, E | 1 |
| Alzamora, M | 1 |
| Marsal, JR | 1 |
| Heras, A | 1 |
| Morros, R | 1 |
| Abo-Salem, OM | 1 |
| Chaves, F | 1 |
| Teixeira, CF | 1 |
| Gutiérrez, JM | 1 |
| Lima, V | 1 |
| Brito, GA | 2 |
| Cunha, FQ | 1 |
| Rebouças, CG | 1 |
| Falcão, BA | 1 |
| Augusto, RF | 1 |
| Souza, ML | 1 |
| Leitão, BT | 1 |
| Ribeiro, RA | 2 |
| Macedo, FY | 1 |
| Baltazar, F | 1 |
| Almeida, PR | 1 |
| Távora, F | 1 |
| Ferreira, FV | 1 |
| Schmitt, FC | 1 |
| Ambrus, JL | 1 |
| Stadler, S | 1 |
| Kulaylat, M | 1 |
| Lerner, MR | 1 |
| Balla, AK | 1 |
| Wilson, MF | 1 |
| Brackett, DJ | 1 |
| Abraham, E | 1 |
| Bursten, S | 1 |
| Shenkar, R | 1 |
| Allbee, J | 1 |
| Tuder, R | 1 |
| Woodson, P | 1 |
| Guidot, DM | 1 |
| Rice, G | 1 |
| Singer, JW | 1 |
| Repine, JE | 1 |
| Ungemach, FR | 1 |
| Wang, P | 2 |
| Ba, ZF | 2 |
| Zhou, M | 1 |
| Tait, SM | 1 |
| Chaudry, IH | 2 |
| Stoltenburg-Didinger, G | 1 |
| Neifer, S | 1 |
| Bienzle, U | 1 |
| Eling, WM | 1 |
| Kremsner, PG | 1 |
| Heller, S | 1 |
| Weber, K | 1 |
| Heller, A | 1 |
| Urbaschek, R | 1 |
| Koch, T | 1 |
| Parker, SJ | 1 |
| Brown, D | 1 |
| Kenward, CE | 1 |
| Watkins, PE | 1 |
| Morrison, MH | 1 |
| Ayala, A | 1 |
| Cherkasov, VL | 1 |
| Nakisbekova, GO | 1 |
| Smolianitskiĭ, AIa | 1 |
| Samotolkin, KN | 1 |
15 other studies available for pentoxifylline and Hemorrhage
| Article | Year |
|---|---|
Safety of cilostazol in peripheral artery disease: a cohort from a primary healthcare electronic database.
Topics: Age Factors; Aged; Aged, 80 and over; Cardiovascular Agents; Cerebrovascular Disorders; Cilostazol; | 2018 |
Uroprotective effect of pentoxifylline in cyclophosphamide-induced hemorrhagic cystitis in rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Antioxidants; Cyclophosphamide; Cystitis; Cytokines; Dis | 2013 |
Role of TNF-alpha, IL-1beta and IL-6 in the local tissue damage induced by Bothrops asper snake venom: an experimental assessment in mice.
Topics: Animals; Bothrops; Crotalid Venoms; Dose-Response Relationship, Drug; Edema; Hemorrhage; Interleukin | 2005 |
Effects of the tumour necrosis factor-alpha inhibitors pentoxifylline and thalidomide in short-term experimental oral mucositis in hamsters.
Topics: Abscess; Animals; Antimetabolites, Antineoplastic; Cricetinae; Disease Models, Animal; Edema; Erythe | 2005 |
Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cystitis; Drug Therapy, Combination; Etorico | 2008 |
Hemorrheologic effects of metabolites of pentoxifylline (Trental).
Topics: Adenosine Diphosphate; Epinephrine; Erythrocyte Deformability; Erythrocyte Membrane; Erythrocytes; H | 1995 |
Pentoxifylline interferes with potential sources of free radical generation during endotoxemia.
Topics: Animals; Blood Glucose; Cardiac Output; Endotoxins; Free Radicals; Heart Rate; Hemodynamics; Hemorrh | 1994 |
Phosphatidic acid signaling mediates lung cytokine expression and lung inflammatory injury after hemorrhage in mice.
Topics: Acyltransferases; Animals; Cell Adhesion; Cells, Cultured; Chemotaxis, Leukocyte; Cytokines; Hemorrh | 1995 |
[Geriatric drugs in aged dogs?].
Topics: Aging; Animals; Cerebral Hemorrhage; Dog Diseases; Dogs; Hemorrhage; Hormones; Pentoxifylline; Proca | 1994 |
Pentoxifylline restores cardiac output and tissue perfusion after trauma-hemorrhage and decreases susceptibility to sepsis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bacterial Infections; Blood Pressure; Ca | 1993 |
Selective damage of hippocampal neurons in murine cerebral malaria prevented by pentoxifylline.
Topics: Animals; Female; Hemorrhage; Hippocampus; Malaria, Cerebral; Mice; Mice, Inbred BALB C; Mice, Inbred | 1993 |
Pentoxifylline improves bacterial clearance during hemorrhage and endotoxemia.
Topics: Animals; Bacteremia; Disease Models, Animal; Drug Evaluation, Preclinical; Endotoxins; Escherichia c | 1999 |
Pentoxifylline fails to improve organ dysfunction and survival when used in the resuscitation of a porcine model of haemorrhage and abdominal sepsis.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hemodynamics; Hemorrhage; | 2000 |
Mechanism of the beneficial effects of pentoxifylline on hepatocellular function after trauma hemorrhage and resuscitation.
Topics: Animals; Blood Pressure; Hemorrhage; Infusions, Intravenous; Interleukin-6; Liver; Male; Pentoxifyll | 1992 |
[The heparin and trental treatment of patients with the hemorrhagic form of erysipelas].
Topics: Adolescent; Adult; Aged; Blood Coagulation; Drug Evaluation; Erysipelas; Female; Hemorrhage; Heparin | 1991 |