pentoxifylline has been researched along with Granuloma in 5 studies
Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The short-term effects of pentoxifylline (PTX) on granulomatous lesions during Schistosoma mansoni infection in Swiss mice were evaluated." | 7.76 | Effects of pentoxifylline during Schistosoma mansoni infection in Swiss mice: an analysis of worm burden, fecundity and liver histopathology. ( Freitas, RM; Mati, VL; Melo, AL, 2010) |
| "Pentoxifylline (PTX) was proved to exert both anti-inflammatory and anti-fibrotic effects, and was used therapeutically in this experimental model to investigate its role alone or with praziquantel (PZQ) in Schistosoma mansoni-infected mice, and to explore its impact on the tissue expression of transforming growth factor-beta1 (TGF-beta1)." | 5.34 | Pharmacodynamics of pentoxifylline and/or praziquantel in murine schistosomiasis mansoni. ( El-Lakkany, N; Nosseir, M, 2007) |
| "The short-term effects of pentoxifylline (PTX) on granulomatous lesions during Schistosoma mansoni infection in Swiss mice were evaluated." | 3.76 | Effects of pentoxifylline during Schistosoma mansoni infection in Swiss mice: an analysis of worm burden, fecundity and liver histopathology. ( Freitas, RM; Mati, VL; Melo, AL, 2010) |
| "Pentoxifylline (PTX) was proved to exert both anti-inflammatory and anti-fibrotic effects, and was used therapeutically in this experimental model to investigate its role alone or with praziquantel (PZQ) in Schistosoma mansoni-infected mice, and to explore its impact on the tissue expression of transforming growth factor-beta1 (TGF-beta1)." | 1.34 | Pharmacodynamics of pentoxifylline and/or praziquantel in murine schistosomiasis mansoni. ( El-Lakkany, N; Nosseir, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mati, VL | 1 |
| Freitas, RM | 1 |
| Melo, AL | 1 |
| Moller, DR | 1 |
| El-Lakkany, N | 1 |
| Nosseir, M | 1 |
| Heinemann, DE | 1 |
| Peters, JH | 1 |
| Gahr, M | 1 |
| Reis, LF | 1 |
| Ventura, TG | 1 |
| Souza, SO | 1 |
| Arana-Pino, A | 1 |
| Pelajo-Machado, M | 1 |
| Pereira, MJ | 1 |
| Lenzi, HL | 1 |
| Conceição, MJ | 1 |
| Takiya, CM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Biomarkers of Disease Activity and Treatment Responses in Patients With CNS Sarcoidosis Treated With H.P. Acthar Gel[NCT02298491] | Phase 4 | 4 participants (Actual) | Interventional | 2016-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Total number of lesions assessed at 1 year (NCT02298491)
Timeframe: 1 year
| Intervention | lesions (Number) |
|---|---|
| H.P. Acthar Gel | 5 |
1 review available for pentoxifylline and Granuloma
| Article | Year |
|---|---|
Treatment of sarcoidosis -- from a basic science point of view.
Topics: Etanercept; Granuloma; Humans; Immunoglobulin G; Immunosuppressive Agents; Interleukins; Pentoxifyll | 2003 |
4 other studies available for pentoxifylline and Granuloma
| Article | Year |
|---|---|
Effects of pentoxifylline during Schistosoma mansoni infection in Swiss mice: an analysis of worm burden, fecundity and liver histopathology.
Topics: Acute Disease; Animals; Chronic Disease; Female; Fertility; Granuloma; Liver; Male; Mice; Parasite E | 2010 |
Pharmacodynamics of pentoxifylline and/or praziquantel in murine schistosomiasis mansoni.
Topics: Animals; Anthelmintics; Disease Models, Animal; Granuloma; Male; Mice; Pentoxifylline; Praziquantel; | 2007 |
A human in vitro granuloma model using heat killed Candida albicans cells immobilized on plastic culture wells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Antibodies; Candida albicans; Cell Culture Techniques; Cell | 1997 |
Quantitative and qualitative interferences of pentoxifillyne on hepatic Schistosoma mansoni granulomas: effects on extracellular matrix and eosinophil population.
Topics: Animals; Collagen; Eosinophils; Extracellular Matrix; Granuloma; Liver Cirrhosis; Liver Diseases, Pa | 2001 |