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pentoxifylline and Fibrosarcoma

pentoxifylline has been researched along with Fibrosarcoma in 8 studies

Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Pentoxifylline caused an increase in alkylator activity against the FSaIIC fibrosarcoma only when used with BCNU; this effect was further augmented by the addition of Fluosol-DA/carbogen."5.28Fluosol-DA/carbogen with lonidamine or pentoxifylline as modulators of alkylating agents in the FSaIIC fibrosarcoma. ( Dezube, B; Frei, E; Herman, TS; Pardee, A; Tanaka, J; Teicher, BA, 1991)
"We hypothesized that the combination of pentoxifylline (PTX) and nicotinamide (NA) can reduce the radioresistance of FSaII murine fibrosarcoma by improving oxygenation of the hypoxic tumour cells."3.68Improved tumour oxygenation and radiosensitization by combination with nicotinamide and pentoxifylline. ( Lee, I; Levitt, SH; Song, CW, 1993)
" The purpose of this study was to examine the effects of PENTO alone or in combination with NA (PENTO + NA) on the oxygenation and radio-response of FSaII murine fibrosarcomas of mice."1.28Increases in tumor response by pentoxifylline alone or in combination with nicotinamide. ( Kim, JH; Lee, I; Levitt, SH; Song, CW, 1992)
"Pentoxifylline caused an increase in alkylator activity against the FSaIIC fibrosarcoma only when used with BCNU; this effect was further augmented by the addition of Fluosol-DA/carbogen."1.28Fluosol-DA/carbogen with lonidamine or pentoxifylline as modulators of alkylating agents in the FSaIIC fibrosarcoma. ( Dezube, B; Frei, E; Herman, TS; Pardee, A; Tanaka, J; Teicher, BA, 1991)
"Etoposide alone was essentially additive with the alkylating drugs for both tumor-cell and bone-marrow killing, except for BCNU, where a substantial increase in tumor-cell killing occurred (0."1.28Etoposide with lonidamine or pentoxifylline as modulators of alkylating agent activity in vivo. ( Dezube, B; Frei, E; Herman, TS; Holden, SA; Tanaka, J; Teicher, BA, 1991)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's6 (75.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fantin, M1
Quintieri, L1
Kúsz, E1
Kis, E1
Glavinas, H1
Floreani, M1
Padrini, R1
Duda, E1
Vizler, C1
Ishibashi, T1
Yamada, H1
Harada, S1
Harada, Y1
Miyazaki, N1
Takamoto, M1
Watanabe, K1
Price, MJ1
Li, LT1
Tward, JD1
Bublik, I1
McBride, WH1
Lavey, RS1
Takahashi, GW1
Montgomery, RB1
Stahl, WL1
Crittenden, CA1
Valentine, MA1
Thorning, DR1
Andrews, DF1
Lilly, MB1
Lee, I2
Levitt, SH2
Song, CW2
Kim, JH1
Teicher, BA2
Herman, TS2
Tanaka, J2
Dezube, B2
Pardee, A1
Frei, E2
Holden, SA1

Other Studies

8 other studies available for pentoxifylline and Fibrosarcoma

ArticleYear
Pentoxifylline and its major oxidative metabolites exhibit different pharmacological properties.
    European journal of pharmacology, 2006, Mar-27, Volume: 535, Issue:1-3

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Li

2006
Distant metastasis facilitated by BCG: spread of tumour cells injected in the BCG-primed site.
    British journal of cancer, 1980, Volume: 41, Issue:4

    Topics: Animals; BCG Vaccine; Blood Cell Count; Erythrocytes; Female; Fibrosarcoma; Immunity; Iodine Radiois

1980
Effect of nicotinamide and pentoxifylline on normal tissue and FSA tumor oxygenation.
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:3

    Topics: Analysis of Variance; Animals; Drug Interactions; Fibrosarcoma; Male; Mice; Mice, Inbred C3H; Muscle

1995
Pentoxifylline inhibits tumor necrosis factor-alpha-mediated cytotoxicity and cytostasis in L929 murine fibrosarcoma cells.
    International journal of immunopharmacology, 1994, Volume: 16, Issue:9

    Topics: Animals; Cell Division; Cell Survival; Fibrosarcoma; Mice; Pentoxifylline; Phospholipases A; Phospho

1994
Improved tumour oxygenation and radiosensitization by combination with nicotinamide and pentoxifylline.
    International journal of radiation biology, 1993, Volume: 64, Issue:2

    Topics: Animals; Drug Combinations; Fibrosarcoma; Laser-Doppler Flowmetry; Mice; Microelectrodes; Niacinamid

1993
Increases in tumor response by pentoxifylline alone or in combination with nicotinamide.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3

    Topics: Animals; Cell Hypoxia; Combined Modality Therapy; Dose-Response Relationship, Radiation; Drug Therap

1992
Fluosol-DA/carbogen with lonidamine or pentoxifylline as modulators of alkylating agents in the FSaIIC fibrosarcoma.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:1

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Bone Marrow; Carbon Dioxide; Cell Survival; Colon

1991
Etoposide with lonidamine or pentoxifylline as modulators of alkylating agent activity in vivo.
    International journal of cancer, 1991, Jun-19, Volume: 48, Issue:4

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; B

1991