pentoxifylline has been researched along with Experimental Radiation Injuries in 18 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "A combination of pentoxifylline (PTX) and tocopherol (TP) is believed to reduce chronic fibrosis and induce bone healing in osteoradionecrosis (ORN) of the mandible, but evidence of its therapeutic effectiveness for cortical bone is lacking." | 3.91 | Effects of pentoxifylline and tocopherol on a rat-irradiated jaw model using micro-CT cortical bone analysis. ( Eo, MY; Kim, SM; Lee, JH; Myoung, H; Nguyen, TTH; Seo, MH, 2019) |
| "The aim of the present study was to investigate whether pentoxifylline (PTX) treatment could protect against induced acute radiation enteritis." | 3.76 | Preventive effect of pentoxifylline on acute radiation damage via antioxidant and anti-inflammatory pathways. ( Ademoğlu, E; Akguner, T; Erbil, Y; Hepgül, G; Olgaç, V; Tanrikulu, S; Unalp, HR, 2010) |
| "Prevention and treatment of radiation-induced late rectal ulcer using deproteinized calf blood serum (ActoHorm) or pentoxifylline." | 3.69 | Modification of late radiation damage in the rectum of rats by deproteinized calf blood serum (ActoHorm) and pentoxifylline (PTX). ( Tamou, S; Trott, KR, 1994) |
| "The pulmonary fibrosis has no known efficient treatment." | 1.40 | The relation of radiation-induced pulmonary fibrosis with stress and the efficiency of antioxidant treatment: an experimental study. ( Bozkurt, KK; Demırpence, Ö; Doğuç, DK; Kaya, V; Şen, CA; Süren, D; Yalçın, AY; Yazkan, R; Yıldırım, M; Yüksel, Ö, 2014) |
| "Pentoxifylline was injected 30 min before exposure, sodium selenite and interleukin 1alpha 24 h before exposure and misoprostol 2 h before exposure." | 1.32 | Novel radioprotectant drugs for sparing radiation-induced damage to the physis. ( Damron, TA; Farnum, CE; Horton, JA; Margulies, BS; Spadaro, JA; Strauss, JA, 2004) |
| "Pentoxifylline is a methylxanthine derivative that produces dose-related improvement in blood flow, lower blood viscosity, improved erythrocyte flexibility, and increased tissue oxygen levels." | 1.31 | Pentoxifylline effects on acute and late complications after radiotherapy in rabbit. ( Aksaray, F; Aygenc, E; Bilgili, H; Celikkanat, S; Kaymakci, M; Orhun, S; Ozdem, C, 2001) |
| "38 g/m2/day, which is comparable to the maximum tolerated dosage in humans." | 1.29 | Effect of high-dose pentoxifylline on acute radiation-induced lung toxicity in a rat lung perfusion model. ( Griffin, TW; Koh, WJ; Peterson, LM; Stelzer, KJ, 1996) |
| "Pentoxifylline is a methyl xanthine derivative that is used to treat vascular occlusive disease in humans." | 1.28 | The effect of pentoxifylline on early and late radiation injury following fractionated irradiation in C3H mice. ( Dion, MW; Hussey, DH; Osborne, JW, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 6 (33.33) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nguyen, TTH | 1 |
| Eo, MY | 1 |
| Seo, MH | 1 |
| Myoung, H | 1 |
| Kim, SM | 1 |
| Lee, JH | 1 |
| Kaya, V | 1 |
| Yazkan, R | 1 |
| Yıldırım, M | 1 |
| Doğuç, DK | 1 |
| Süren, D | 1 |
| Bozkurt, KK | 1 |
| Yüksel, Ö | 1 |
| Demırpence, Ö | 1 |
| Şen, CA | 1 |
| Yalçın, AY | 1 |
| Moura, JF | 1 |
| Mota, JM | 1 |
| Leite, CA | 1 |
| Wong, DV | 1 |
| Bezerra, NP | 1 |
| Brito, GA | 1 |
| Lima, V | 1 |
| Cunha, FQ | 1 |
| Ribeiro, RA | 1 |
| Boerma, M | 1 |
| Roberto, KA | 1 |
| Hauer-Jensen, M | 1 |
| Hepgül, G | 1 |
| Tanrikulu, S | 1 |
| Unalp, HR | 1 |
| Akguner, T | 1 |
| Erbil, Y | 1 |
| Olgaç, V | 1 |
| Ademoğlu, E | 1 |
| Halle, M | 1 |
| Tornvall, P | 1 |
| Stelzer, KJ | 2 |
| Koh, WJ | 2 |
| Peterson, LM | 2 |
| Griffin, TW | 2 |
| Damron, TA | 2 |
| Spadaro, JA | 2 |
| Horton, JA | 2 |
| Margulies, BS | 2 |
| Strauss, JA | 2 |
| Farnum, CE | 2 |
| Yilmaz, T | 1 |
| Aydemir, O | 1 |
| Ozercan, IH | 1 |
| Ustundağ, B | 1 |
| Remiszewski, P | 1 |
| Roszkowski, K | 1 |
| Staker, BL | 1 |
| Ward, WF | 2 |
| Russell, KJ | 1 |
| Tamou, S | 1 |
| Trott, KR | 1 |
| Oberyszyn, TM | 1 |
| Tober, KL | 1 |
| Ross, MS | 1 |
| Robertson, FM | 1 |
| Aygenc, E | 1 |
| Celikkanat, S | 1 |
| Bilgili, H | 1 |
| Aksaray, F | 1 |
| Orhun, S | 1 |
| Kaymakci, M | 1 |
| Ozdem, C | 1 |
| Kim, YT | 1 |
| Molteni, A | 1 |
| Ts'ao, C | 1 |
| Hinz, JM | 1 |
| Brook, I | 1 |
| Elliott, TB | 1 |
| Dion, MW | 1 |
| Hussey, DH | 1 |
| Osborne, JW | 1 |
1 review available for pentoxifylline and Experimental Radiation Injuries
| Article | Year |
|---|---|
[Mechanisms of radiation to the lung. Pentoxifylline--a new radioprotective drug?].
Topics: Animals; Humans; Lung; Lung Diseases; Pentoxifylline; Radiation Injuries, Experimental; Radiation-Pr | 1995 |
17 other studies available for pentoxifylline and Experimental Radiation Injuries
| Article | Year |
|---|---|
Effects of pentoxifylline and tocopherol on a rat-irradiated jaw model using micro-CT cortical bone analysis.
Topics: Animals; Antioxidants; Bone Diseases, Metabolic; Cortical Bone; Fibrosis; Male; Mandible; Osteoradio | 2019 |
The relation of radiation-induced pulmonary fibrosis with stress and the efficiency of antioxidant treatment: an experimental study.
Topics: Animals; Antioxidants; Ascorbic Acid; Histological Techniques; Pentoxifylline; Pulmonary Fibrosis; R | 2014 |
A novel model of megavoltage radiation-induced oral mucositis in hamsters: Role of inflammatory cytokines and nitric oxide.
Topics: Animals; Cobalt Radioisotopes; Cricetinae; Cytokines; Disease Models, Animal; Guanidines; Head and N | 2015 |
Prevention and treatment of functional and structural radiation injury in the rat heart by pentoxifylline and alpha-tocopherol.
Topics: alpha-Tocopherol; Animals; Cell Count; Collagen Type I; Collagen Type III; Cytoskeleton; Diastole; F | 2008 |
Preventive effect of pentoxifylline on acute radiation damage via antioxidant and anti-inflammatory pathways.
Topics: Acute Disease; Animals; Dinoprostone; Enteritis; Glutathione; Ileum; Immunohistochemistry; Intercell | 2010 |
Beyond nuclear factor kappaB in cardiovascular disease induced by radiotherapy.
Topics: Animals; Cardiovascular Diseases; Heart; Humans; NF-kappa B; Pentoxifylline; Radiation Injuries, Exp | 2011 |
Effect of high-dose pentoxifylline on acute radiation-induced lung toxicity in a rat lung perfusion model.
Topics: Acute Disease; Animals; Lung; Male; Pentoxifylline; Pilot Projects; Radiation Injuries, Experimental | 1996 |
Novel radioprotectant drugs for sparing radiation-induced damage to the physis.
Topics: Animals; Bone Development; Bone Regeneration; Interleukin-1; Leg Bones; Leg Length Inequality; Male; | 2004 |
Combinations of radioprotectants spare radiation-induced damage to the physis.
Topics: Amifostine; Animals; Body Weight; Bone Density; Bone Development; Drug Therapy, Combination; Femur; | 2004 |
Effects of vitamin e, pentoxifylline and aprotinin on light-induced retinal injury.
Topics: Animals; Antioxidants; Aprotinin; Drug Therapy, Combination; Eye Burns; Guinea Pigs; Injections, Int | 2007 |
Effect of pentoxifylline on radiation-induced lung and skin toxicity in rats.
Topics: Animals; Lung; Male; Pentoxifylline; Peptidyl-Dipeptidase A; Pulmonary Circulation; Radiation Injuri | 1995 |
Modification of late radiation damage in the rectum of rats by deproteinized calf blood serum (ActoHorm) and pentoxifylline (PTX).
Topics: Actihaemyl; Animals; Blood Proteins; Drug Evaluation, Preclinical; Female; Male; Pentoxifylline; Rad | 1994 |
Inhibitory effects of pentoxifylline on ultraviolet B light-induced cutaneous inflammation.
Topics: Animals; Biomarkers; Cell Division; Inflammation; Mice; Mice, Hairless; Neutrophils; Pentoxifylline; | 1998 |
Pentoxifylline effects on acute and late complications after radiotherapy in rabbit.
Topics: Animals; Erythema; Pentoxifylline; Rabbits; Radiation Injuries, Experimental; Radiation-Protective A | 2001 |
Pentoxifylline does not spare acute radiation reactions in rat lung and skin.
Topics: Administration, Oral; Animals; Lung; Male; Pentoxifylline; Radiation Injuries, Experimental; Rats; R | 1992 |
Treatment of wound sepsis in irradiated mice.
Topics: Animals; Cobalt Radioisotopes; Female; Gamma Rays; Immunity; Immunoglobulin G; Mice; Penicillin G; P | 1989 |
The effect of pentoxifylline on early and late radiation injury following fractionated irradiation in C3H mice.
Topics: Animals; Dose-Response Relationship, Radiation; Male; Mice; Mice, Inbred C3H; Pentoxifylline; Radiat | 1989 |