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pentoxifylline and Escherichia coli Infections

pentoxifylline has been researched along with Escherichia coli Infections in 24 studies

Escherichia coli Infections: Infections with bacteria of the species ESCHERICHIA COLI.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficiency of pentoxifylline (PTX), a methyl xanthine derivative, in preventing renal scar formation after the induction of pyelonephritis in an experimental rat model with delayed antimicrobial therapy."7.72Preventive effect of pentoxifylline on renal scarring in rat model of pyelonephritis. ( Boleken, ME; Dindar, H; Ertoy, D; Gokcora, IH; Ozsan, M; Yagmurlu, A, 2003)
"The aim of this study was to investigate whether the methylxanthine-derivative pentoxifylline (PTX) affects bacterial clearance of the organism in states of hemorrhage and endotoxemia."7.70Pentoxifylline improves bacterial clearance during hemorrhage and endotoxemia. ( Heller, A; Heller, S; Koch, T; Urbaschek, R; Weber, K, 1999)
"To compare effects of a single dose of pentoxifylline (PTX), flunixin meglumine (FM), and their combination (FM/PTX) in a model of equine endotoxemia."7.69Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses. ( Anders, B; Barton, MH; Baskett, A; Moore, JN; Norton, N, 1997)
"Since fungal septic shock with acute disseminated candidiasis evolves prior to significant increases in circulating TNF, PTX also appears ineffective in its treatment."5.29Effects of pentoxifylline on tumor necrosis factor production and survival during lethal E. coli sepsis vs. disseminated candidiasis with fungal septic shock. ( Lechner, AJ; Matuschak, GM; Potthoff, LH; Rouben, LR; Tredway, TL, 1993)
"To evaluate the efficiency of pentoxifylline (PTX), a methyl xanthine derivative, in preventing renal scar formation after the induction of pyelonephritis in an experimental rat model with delayed antimicrobial therapy."3.72Preventive effect of pentoxifylline on renal scarring in rat model of pyelonephritis. ( Boleken, ME; Dindar, H; Ertoy, D; Gokcora, IH; Ozsan, M; Yagmurlu, A, 2003)
"The aim of this study was to investigate whether the methylxanthine-derivative pentoxifylline (PTX) affects bacterial clearance of the organism in states of hemorrhage and endotoxemia."3.70Pentoxifylline improves bacterial clearance during hemorrhage and endotoxemia. ( Heller, A; Heller, S; Koch, T; Urbaschek, R; Weber, K, 1999)
"To compare effects of a single dose of pentoxifylline (PTX), flunixin meglumine (FM), and their combination (FM/PTX) in a model of equine endotoxemia."3.69Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses. ( Anders, B; Barton, MH; Baskett, A; Moore, JN; Norton, N, 1997)
"The inhibitory effect of chlorpromazine (CPZ), pentoxifylline (PTX) and dexamethasone (DEX) was investigated in a model of endotoxin shock in Holstein calves following an intravenous administration of Esherichia coli endotoxin (LPS)."3.69Inhibitory effect on LPS-induced tumor necrosis factor in calves treated with chlorpromazine or pentoxifylline. ( Higuchi, T; Matsuzawa, H; Ohtsuka, H; Sato, H; Takahashi, J; Takahashi, K; Yoshino, TO, 1997)
"We postulated that PTX treatment in acute endotoxemia downregulates the inflammatory response and may decrease lung injury."1.33LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition: effects on proinflammatory mediators, metalloproteinases, NF-kappaB, and ICAM-1 expression. ( Coimbra, R; Hoyt, DB; Loomis, W; Melbostad, H; Porcides, RD; Tobar, M; Wolf, P, 2006)
"Since fungal septic shock with acute disseminated candidiasis evolves prior to significant increases in circulating TNF, PTX also appears ineffective in its treatment."1.29Effects of pentoxifylline on tumor necrosis factor production and survival during lethal E. coli sepsis vs. disseminated candidiasis with fungal septic shock. ( Lechner, AJ; Matuschak, GM; Potthoff, LH; Rouben, LR; Tredway, TL, 1993)
"coli septicemia plus PTXF bolus 20 mg/kg injected 5 min before E."1.27Attenuation of acute lung injury in septic guinea pigs by pentoxifylline. ( Harada, H; Hogue, RS; Ishizaka, A; O'Hanley, PT; Raffin, TA; Stephens, KE; Wu, ZH, 1988)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19904 (16.67)18.7374
1990's13 (54.17)18.2507
2000's6 (25.00)29.6817
2010's1 (4.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Groesdonk, HV1
Bauer, A1
Kreft, B1
Heringlake, M1
Paarmann, H1
Pagel, H1
Oliveira-Júnior, IS2
Oliveira, IS1
Oliveira, WR1
Cavassani, SS1
Brunialti, MK2
Salomao, R2
Yagmurlu, A1
Boleken, ME1
Ertoy, D1
Ozsan, M1
Gokcora, IH1
Dindar, H1
Okayama, A1
Mikasa, K1
Matsui, N1
Higashi, N1
Miyamoto, M1
Kita, E1
Coimbra, R1
Melbostad, H1
Loomis, W1
Porcides, RD1
Wolf, P1
Tobar, M1
Hoyt, DB1
Koh, IH1
Junqueira, VB1
Breuillé, D3
Farge, MC1
Rosé, F1
Arnal, M1
Attaix, D1
Obled, C3
Lechner, AJ1
Rouben, LR1
Potthoff, LH1
Tredway, TL1
Matuschak, GM1
Krysztopik, RJ1
Bentley, FR1
Wilson, MA1
Spain, DA1
Garrison, RN1
Santos, AA1
Wilmore, DW1
Bengtsson, A1
Redl, H1
Schlag, G1
Mollnes, TE1
Högåsen, K1
Baskett, A1
Barton, MH1
Norton, N1
Anders, B1
Moore, JN1
Ohtsuka, H1
Higuchi, T1
Matsuzawa, H1
Sato, H1
Takahashi, K1
Takahashi, J1
Yoshino, TO1
Voisin, L2
Ruot, B1
Rallière, C1
Rambourdin, F1
Dalle, M1
Heller, S1
Weber, K1
Heller, A1
Urbaschek, R1
Koch, T1
Vary, T1
Dardevet, D1
Grizard, J1
Buffiere, C1
Denis, P1
Mazolewski, PJ1
Barber, A1
Williams, S1
Simoni, J1
Davis, S1
Shires, GT1
Park, WS1
Chang, YS1
Lee, M1
Hoffmann, H2
Hatherill, JR3
Crowley, J1
Harada, H3
Yonemaru, M3
Zheng, H3
Ishizaka, A4
Raffin, TA4
Chung, TW1
O'Rear, EA2
Whitsett, TL2
Hinshaw, LB2
Smith, MA1
Mallick, AA1
Lilly, CM1
O'Hanley, PT2
Fujishima, S1
Wu, ZH1
Stephens, KE1
Hogue, RS1
Puranapanda, V1
Chang, AC1

Trials

1 trial available for pentoxifylline and Escherichia coli Infections

ArticleYear
The systemic inflammatory response: perspective of human endotoxemia.
    Shock (Augusta, Ga.), 1996, Volume: 6 Suppl 1

    Topics: Body Temperature; Cytokines; Endotoxemia; Endotoxins; Escherichia coli Infections; Heart Rate; Human

1996

Other Studies

23 other studies available for pentoxifylline and Escherichia coli Infections

ArticleYear
Urodilatin and pentoxifylline prevent the early onset of Escherichia coli-induced acute renal failure in a model of isolated perfused rat kidney.
    Kidney & blood pressure research, 2009, Volume: 32, Issue:2

    Topics: Acute Kidney Injury; Animals; Atrial Natriuretic Factor; Disease Models, Animal; Escherichia coli In

2009
Effects of pentoxifylline on inflammation and lung dysfunction in ventilated septic animals.
    The Journal of trauma, 2010, Volume: 68, Issue:4

    Topics: Acute Disease; Analysis of Variance; Animals; Bronchoalveolar Lavage; Disease Models, Animal; Enzyme

2010
Preventive effect of pentoxifylline on renal scarring in rat model of pyelonephritis.
    Urology, 2003, Volume: 61, Issue:5

    Topics: Acute Disease; Animals; Cicatrix; Disease Models, Animal; Escherichia coli; Escherichia coli Infecti

2003
An interventional approach to block brain damage caused by Shiga toxin-producing Escherichia coli infection, by use of a combination of phosphodiesterase inhibitors.
    The Journal of infectious diseases, 2004, Dec-15, Volume: 190, Issue:12

    Topics: Animals; Antigens, Tumor-Associated, Carbohydrate; Brain Diseases; Cecum; Cells, Cultured; Cytokines

2004
LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition: effects on proinflammatory mediators, metalloproteinases, NF-kappaB, and ICAM-1 expression.
    The Journal of trauma, 2006, Volume: 60, Issue:1

    Topics: Animals; Disease Models, Animal; Endotoxemia; Escherichia coli Infections; Intercellular Adhesion Mo

2006
Effect of pentoxifylline on lung inflammation and gas exchange in a sepsis-induced acute lung injury model.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2006, Volume: 39, Issue:11

    Topics: Acute Disease; Animals; Disease Models, Animal; Escherichia coli Infections; Inflammation; Inflammat

2006
Pentoxifylline decreases body weight loss and muscle protein wasting characteristics of sepsis.
    The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 1

    Topics: Animals; Eating; Escherichia coli Infections; Liver; Male; Muscle Proteins; Muscles; Pentoxifylline;

1993
Effects of pentoxifylline on tumor necrosis factor production and survival during lethal E. coli sepsis vs. disseminated candidiasis with fungal septic shock.
    Circulatory shock, 1993, Volume: 39, Issue:4

    Topics: Animals; Bacteremia; Candidiasis; Escherichia coli Infections; Fungemia; Gene Expression; Male; Pent

1993
Vasomotor response to pentoxifylline mediates improved renal blood flow to bacteremia.
    The Journal of surgical research, 1996, Volume: 63, Issue:1

    Topics: Animals; Arterioles; Bacteremia; Blood Pressure; Cardiac Output; Escherichia coli Infections; Heart

1996
Effects on complement activation and cytokine (TNF-alpha and IL-8) release of infusion of anti-TNF-antibodies or a xanthine derivative (HWA 138) in septic baboons.
    Acta anaesthesiologica Scandinavica, 1996, Volume: 40, Issue:2

    Topics: Animals; Antibodies; Complement Activation; Complement Membrane Attack Complex; Escherichia coli Inf

1996
Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses.
    American journal of veterinary research, 1997, Volume: 58, Issue:11

    Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal

1997
Inhibitory effect on LPS-induced tumor necrosis factor in calves treated with chlorpromazine or pentoxifylline.
    The Journal of veterinary medical science, 1997, Volume: 59, Issue:11

    Topics: Animals; Cattle; Chlorpromazine; Dexamethasone; Endotoxins; Escherichia coli Infections; Female; Lip

1997
Cytokine modulation by PX differently affects specific acute phase proteins during sepsis in rats.
    The American journal of physiology, 1998, Volume: 275, Issue:5

    Topics: Acute-Phase Proteins; Animals; Escherichia coli Infections; Free Radical Scavengers; Interleukin-1;

1998
Pentoxifylline improves bacterial clearance during hemorrhage and endotoxemia.
    Critical care medicine, 1999, Volume: 27, Issue:4

    Topics: Animals; Bacteremia; Disease Models, Animal; Drug Evaluation, Preclinical; Endotoxins; Escherichia c

1999
Pentoxifylline improves insulin action limiting skeletal muscle catabolism after infection.
    The Journal of endocrinology, 1999, Volume: 163, Issue:1

    Topics: Analysis of Variance; Animals; Culture Techniques; Escherichia coli Infections; Forelimb; Insulin; M

1999
Attenuating tumor necrosis factor alpha does not ameliorate other cytokine and peroxidase products during sepsis.
    American journal of surgery, 1999, Volume: 178, Issue:6

    Topics: Animals; Benzyl Compounds; Cytokines; Dexamethasone; Drug Combinations; Escherichia coli Infections;

1999
The efficacy of pentoxifylline as an anti-inflammatory agent in experimental Escherichia coli meningitis in the newborn piglet.
    Biology of the neonate, 2000, Volume: 77, Issue:4

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Brain; Cerebral Cortex; Cerebrospinal Fluid; Co

2000
Early post-treatment with pentoxifylline or dibutyryl cAMP attenuates Escherichia coli-induced acute lung injury in guinea pigs.
    The American review of respiratory disease, 1991, Volume: 143, Issue:2

    Topics: Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Bucladesine; Endotoxins; Escherichia coli; Es

1991
Survival factors in a canine septic shock model.
    Circulatory shock, 1991, Volume: 33, Issue:3

    Topics: Animals; Blood Pressure; Disease Models, Animal; Dogs; Erythrocyte Deformability; Escherichia coli I

1991
The effects of aminophylline and pentoxifylline on multiple organ damage after Escherichia coli sepsis.
    The American review of respiratory disease, 1989, Volume: 140, Issue:4

    Topics: Albumins; Aminophylline; Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Edema; Escherichia c

1989
Attenuation of acute lung injury in septic guinea-pigs by a new xanthine derivative (HWA-138).
    Pharmatherapeutica, 1989, Volume: 5, Issue:6

    Topics: Acute Disease; Animals; Blood Pressure; Bronchodilator Agents; Erythrocytes; Escherichia coli Infect

1989
Attenuation of acute lung injury in septic guinea pigs by pentoxifylline.
    The American review of respiratory disease, 1988, Volume: 138, Issue:2

    Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Escherichia coli Infections; Female; Glucuroni

1988
Erythrocyte deformability in canine septic shock and the efficacy of pentoxifylline and a leukotriene antagonist.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1987, Volume: 185, Issue:2

    Topics: Acetophenones; Animals; Azoles; Dogs; Erythrocyte Deformability; Escherichia coli Infections; Female

1987