pentoxifylline has been researched along with Endometrioma in 14 studies
Endometrioma: An enlarged area of ENDOMETRIOSIS that resembles a tumor. It is usually found in the OVARY. When it is filled with old blood, it is known as a chocolate cyst.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among 98 patients finally considered in the evaluation of the results, the 6 month overall pregnancy rates were 28 and 14% in the pentoxifylline and placebo groups, respectively." | 9.13 | Combined laparoscopic surgery and pentoxifylline therapy for treatment of endometriosis-associated infertility: a preliminary trial. ( Balasch, J; Carmona, F; Creus, M; del Pino, M; Fábregues, F; Manau, D, 2008) |
| "To determine the effectiveness and safety of pentoxifylline in the management of endometriosis." | 9.12 | Pentoxifylline for the treatment of endometriosis-associated pain and infertility. ( Becker, CM; Georgiou, EX; Grammatis, AL, 2021) |
| "The present study is the first prospective randomized controlled trial of the effect of pentoxifylline on future fertility in infertile women with asymptomatic minimal or mild endometriosis." | 9.08 | Pentoxifylline versus placebo in the treatment of infertility associated with minimal or mild endometriosis: a pilot randomized clinical trial. ( Balasch, J; Carmona, F; Creus, M; Fábregues, F; Manau, D; Martínez-Román, S; Vanrell, JA, 1997) |
| "To assess the effects of pentoxifylline, which has anti-inflammatory effects, in subfertile, premenopausal women for the management of endometriosis." | 8.88 | Pentoxifylline for endometriosis. ( Clarke, J; Li, Y; Lu, D; Shi, G; Song, H, 2012) |
| "To determine the effectiveness and safety of pentoxifylline, which has anti-inflammatory effects, in the management of endometriosis in subfertile, premenopausal women." | 8.85 | Pentoxifylline versus medical therapies for subfertile women with endometriosis. ( Clarke, J; Li, Y; Lv, D; Shi, G; Song, H, 2009) |
| "This study investigated the effects of pentoxifylline (PTX), high intensity interval training (HIIT) and moderate intensity continuous training (MICT) separately and in combination, on inflammatory and apoptotic pathways in the rat model of induced endometriosis." | 8.31 | High intensity interval training is superior to moderate intensity continuous training in enhancing the anti-inflammatory and apoptotic effect of pentoxifylline in the rat model of endometriosis. ( Akbarzade-Jahromi, M; Jahromi, BN; Jahromi, MK; Nemati, J; Salehpoor, Z; Tanideh, N, 2023) |
| "Our results suggest that the oral administration of pentoxifylline may be an alternative to current therapies for endometriosis." | 7.85 | Oral Administration of Pentoxifylline Reduces Endometriosis-Like Lesions in a Nude Mouse Model. ( Balasch, J; Carmona, F; Castillo, P; González-Foruria, I; Lozano, F; Martínez-Florensa, M; Perelló, M, 2017) |
| "To investigate the effects of pentoxifylline, on vascular endothelial growth factor (VEGF)-C and flk-1 expression in the rat endometriosis model." | 7.76 | Effect of pentoxifylline on vascular endothelial growth factor C and flk-1 expression on endometrial implants in the rat endometriosis model. ( Creatsas, G; Deliveliotou, A; Gregoriou, O; Lai, J; Perrea, D; Vlachos, A; Vlahos, NF; Zhao, Y, 2010) |
| "Evaluation of the pentoxifilline and verapamil influence on the phagocytic activity of the peritoneal macrophages from women with endometriosis." | 7.70 | [Pentoxifylline and verapamil influence on the phagocytosis of peritoneal macrophages from women with endometriosis]. ( Czygier, M; Laudański, P; Szamatowicz, J, 2000) |
| "To determine the effect of pentoxifylline on early reproductive performance in an animal model for endometriosis." | 7.68 | Immunomodulation in the treatment of endometriosis-associated subfertility: use of pentoxifylline to reverse the inhibition of fertilization by surgically induced endometriosis in a rodent model. ( Lambert, H; Roy, S; Serpa, N; Steinleitner, A; Suarez, M, 1991) |
| "Pentoxifylline could increase the lymphocyte count and decrease the neutrophil count in serum, and because these changes it might alter the immune system." | 5.35 | Evaluation of the effect of pentoxifylline on white blood cell count in serum and peritoneal fluid in female rats with endometriosis. ( Akhondi, MM; Ghaffari Novin, M; Heidari, M; Jeddi-Tehrani, M; Mohammadzadeh, A; Mohammadzadeh, F; Soltanghoraee, H; Zeraati, H, 2008) |
| "Among 98 patients finally considered in the evaluation of the results, the 6 month overall pregnancy rates were 28 and 14% in the pentoxifylline and placebo groups, respectively." | 5.13 | Combined laparoscopic surgery and pentoxifylline therapy for treatment of endometriosis-associated infertility: a preliminary trial. ( Balasch, J; Carmona, F; Creus, M; del Pino, M; Fábregues, F; Manau, D, 2008) |
| "To determine the effectiveness and safety of pentoxifylline in the management of endometriosis." | 5.12 | Pentoxifylline for the treatment of endometriosis-associated pain and infertility. ( Becker, CM; Georgiou, EX; Grammatis, AL, 2021) |
| "The present study is the first prospective randomized controlled trial of the effect of pentoxifylline on future fertility in infertile women with asymptomatic minimal or mild endometriosis." | 5.08 | Pentoxifylline versus placebo in the treatment of infertility associated with minimal or mild endometriosis: a pilot randomized clinical trial. ( Balasch, J; Carmona, F; Creus, M; Fábregues, F; Manau, D; Martínez-Román, S; Vanrell, JA, 1997) |
| "To assess the effects of pentoxifylline, which has anti-inflammatory effects, in subfertile, premenopausal women for the management of endometriosis." | 4.88 | Pentoxifylline for endometriosis. ( Clarke, J; Li, Y; Lu, D; Shi, G; Song, H, 2012) |
| "To determine the effectiveness and safety of pentoxifylline, which has anti-inflammatory effects, in the management of endometriosis in subfertile, premenopausal women." | 4.85 | Pentoxifylline versus medical therapies for subfertile women with endometriosis. ( Clarke, J; Li, Y; Lv, D; Shi, G; Song, H, 2009) |
| "This study investigated the effects of pentoxifylline (PTX), high intensity interval training (HIIT) and moderate intensity continuous training (MICT) separately and in combination, on inflammatory and apoptotic pathways in the rat model of induced endometriosis." | 4.31 | High intensity interval training is superior to moderate intensity continuous training in enhancing the anti-inflammatory and apoptotic effect of pentoxifylline in the rat model of endometriosis. ( Akbarzade-Jahromi, M; Jahromi, BN; Jahromi, MK; Nemati, J; Salehpoor, Z; Tanideh, N, 2023) |
| "Our results suggest that the oral administration of pentoxifylline may be an alternative to current therapies for endometriosis." | 3.85 | Oral Administration of Pentoxifylline Reduces Endometriosis-Like Lesions in a Nude Mouse Model. ( Balasch, J; Carmona, F; Castillo, P; González-Foruria, I; Lozano, F; Martínez-Florensa, M; Perelló, M, 2017) |
| "To investigate the effects of pentoxifylline, on vascular endothelial growth factor (VEGF)-C and flk-1 expression in the rat endometriosis model." | 3.76 | Effect of pentoxifylline on vascular endothelial growth factor C and flk-1 expression on endometrial implants in the rat endometriosis model. ( Creatsas, G; Deliveliotou, A; Gregoriou, O; Lai, J; Perrea, D; Vlachos, A; Vlahos, NF; Zhao, Y, 2010) |
| "Evaluation of the pentoxifilline and verapamil influence on the phagocytic activity of the peritoneal macrophages from women with endometriosis." | 3.70 | [Pentoxifylline and verapamil influence on the phagocytosis of peritoneal macrophages from women with endometriosis]. ( Czygier, M; Laudański, P; Szamatowicz, J, 2000) |
| "To determine the effect of pentoxifylline on early reproductive performance in an animal model for endometriosis." | 3.68 | Immunomodulation in the treatment of endometriosis-associated subfertility: use of pentoxifylline to reverse the inhibition of fertilization by surgically induced endometriosis in a rodent model. ( Lambert, H; Roy, S; Serpa, N; Steinleitner, A; Suarez, M, 1991) |
| "Endometriosis is an enigmatic, debilitating disease which affects as many as 15% of all women of reproductive age and is characterized by pelvic pain and infertility." | 2.46 | Endometriosis: in search of optimal treatment. ( Nothnick, WB, 2010) |
| "Pentoxifylline could increase the lymphocyte count and decrease the neutrophil count in serum, and because these changes it might alter the immune system." | 1.35 | Evaluation of the effect of pentoxifylline on white blood cell count in serum and peritoneal fluid in female rats with endometriosis. ( Akhondi, MM; Ghaffari Novin, M; Heidari, M; Jeddi-Tehrani, M; Mohammadzadeh, A; Mohammadzadeh, F; Soltanghoraee, H; Zeraati, H, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Salehpoor, Z | 1 |
| Jahromi, BN | 1 |
| Tanideh, N | 1 |
| Nemati, J | 1 |
| Akbarzade-Jahromi, M | 1 |
| Jahromi, MK | 1 |
| Grammatis, AL | 1 |
| Georgiou, EX | 1 |
| Becker, CM | 1 |
| Perelló, M | 1 |
| González-Foruria, I | 1 |
| Castillo, P | 1 |
| Martínez-Florensa, M | 1 |
| Lozano, F | 1 |
| Balasch, J | 3 |
| Carmona, F | 3 |
| Mohammadzadeh, A | 1 |
| Heidari, M | 1 |
| Soltanghoraee, H | 1 |
| Jeddi-Tehrani, M | 1 |
| Ghaffari Novin, M | 1 |
| Akhondi, MM | 1 |
| Zeraati, H | 1 |
| Mohammadzadeh, F | 1 |
| Vlahos, NF | 1 |
| Gregoriou, O | 1 |
| Deliveliotou, A | 1 |
| Perrea, D | 1 |
| Vlachos, A | 1 |
| Zhao, Y | 1 |
| Lai, J | 1 |
| Creatsas, G | 1 |
| Lv, D | 1 |
| Song, H | 2 |
| Li, Y | 2 |
| Clarke, J | 2 |
| Shi, G | 2 |
| Nothnick, WB | 1 |
| Lu, D | 1 |
| Creus, M | 2 |
| Fábregues, F | 2 |
| del Pino, M | 1 |
| Manau, D | 2 |
| Damirov, MM | 1 |
| Kulakov, VI | 1 |
| Bakuleva, LP | 1 |
| Shabanov, AM | 1 |
| Sarkisov, SE | 1 |
| Sliusar', NN | 1 |
| Martínez-Román, S | 1 |
| Vanrell, JA | 1 |
| Szamatowicz, J | 1 |
| Laudański, P | 1 |
| Czygier, M | 1 |
| Steinleitner, A | 2 |
| Lambert, H | 2 |
| Suarez, M | 1 |
| Serpa, N | 1 |
| Roy, S | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Combined Laparoscopic Surgery and Pentoxifylline Therapy for Treatment of Endometriosis-Associated Infertility: A Preliminary Study[NCT00632697] | Phase 3 | 104 participants (Actual) | Interventional | 2001-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for pentoxifylline and Endometrioma
| Article | Year |
|---|---|
Pentoxifylline for the treatment of endometriosis-associated pain and infertility.
Topics: Endometriosis; Female; Humans; Infertility, Female; Live Birth; Pain; Pentoxifylline; Pregnancy; Pre | 2021 |
Pentoxifylline versus medical therapies for subfertile women with endometriosis.
Topics: Endometriosis; Female; Humans; Immunologic Factors; Infertility, Female; Pentoxifylline; Pregnancy; | 2009 |
Endometriosis: in search of optimal treatment.
Topics: Adalimumab; Anastrozole; Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antibodie | 2010 |
Pentoxifylline for endometriosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Endometriosis; Female; Humans; Immunologic | 2012 |
2 trials available for pentoxifylline and Endometrioma
| Article | Year |
|---|---|
Combined laparoscopic surgery and pentoxifylline therapy for treatment of endometriosis-associated infertility: a preliminary trial.
Topics: Adult; Combined Modality Therapy; Endometriosis; Female; Humans; Immunologic Factors; Infertility, F | 2008 |
Pentoxifylline versus placebo in the treatment of infertility associated with minimal or mild endometriosis: a pilot randomized clinical trial.
Topics: Adjuvants, Immunologic; Endometriosis; Female; Humans; Infertility; Pentoxifylline; Pilot Projects; | 1997 |
8 other studies available for pentoxifylline and Endometrioma
| Article | Year |
|---|---|
High intensity interval training is superior to moderate intensity continuous training in enhancing the anti-inflammatory and apoptotic effect of pentoxifylline in the rat model of endometriosis.
Topics: Animals; Anti-Inflammatory Agents; Endometriosis; Female; High-Intensity Interval Training; Humans; | 2023 |
Oral Administration of Pentoxifylline Reduces Endometriosis-Like Lesions in a Nude Mouse Model.
Topics: Administration, Oral; Animals; Disease Models, Animal; Endometriosis; Endometrium; Female; Mice; Mic | 2017 |
Evaluation of the effect of pentoxifylline on white blood cell count in serum and peritoneal fluid in female rats with endometriosis.
Topics: Animals; Ascitic Fluid; Endometriosis; Female; Leukocyte Count; Neutrophils; Pentoxifylline; Rats; R | 2008 |
Effect of pentoxifylline on vascular endothelial growth factor C and flk-1 expression on endometrial implants in the rat endometriosis model.
Topics: Angiogenesis Inhibitors; Animals; Disease Models, Animal; Endometriosis; Endometrium; Female; Infert | 2010 |
[The clinical picture, diagnosis and treatment of the corpus-isthmus location of uterine endometriosis interna].
Topics: Adult; Chronic Disease; Drug Therapy, Combination; Endometriosis; Endometrium; Fat Emulsions, Intrav | 1993 |
[Pentoxifylline and verapamil influence on the phagocytosis of peritoneal macrophages from women with endometriosis].
Topics: Adult; Calcium Channel Blockers; Endometriosis; Female; Humans; Macrophages, Peritoneal; Pentoxifyll | 2000 |
Immunomodulation in the treatment of endometriosis-associated subfertility: use of pentoxifylline to reverse the inhibition of fertilization by surgically induced endometriosis in a rodent model.
Topics: Adjuvants, Immunologic; Animals; Cricetinae; Endometriosis; Female; Fertilization; Gametogenesis; In | 1991 |
Immunomodulation with pentoxifylline abrogates macrophage-mediated infertility in an in vivo model: a paradigm for a novel approach to the treatment of endometriosis-associated subfertility.
Topics: Adjuvants, Immunologic; Animals; Disease Models, Animal; Endometriosis; Female; Fertilization; Infer | 1991 |