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pentoxifylline and Diabetic Retinopathy

pentoxifylline has been researched along with Diabetic Retinopathy in 13 studies

Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

Research Excerpts

ExcerptRelevanceReference
"Pentoxifylline was administered daily at an oral dose of 400 mg tid in the diabetic patients for nine months."5.29Effects of pentoxifylline on choroidal blood flow in nonproliferative diabetic retinopathy. ( Brown, S; Charles, MA; Sadun, AA; Sebag, J; Tang, M, 1994)
"Our results suggest that pentoxifylline may have a protective action for diabetic retinopathy and might modulate risk factors for atherosclerosis in type 1 diabetes."5.17Pentoxifylline treatment for protecting diabetic retinopaty in children with type 1 diabetes. ( Atabek, ME; Baykara, M; Eklioglu, BS; Kurtoglu, S, 2013)
"Treatment with pentoxifylline resulted in a 23."2.67Pentoxifylline increases retinal capillary blood flow velocity in patients with diabetes. ( Hatchell, DL; Kelly, LW; Sinclair, SH; Sonkin, PL, 1993)
"A long-term trial with oral pentoxifylline ("Trental" 400) in a dosage of 1200 mg per day was carried out in 70 diabetic patients with and without vascular afflictions."1.27Diabetic retinal vascular complications and erythrocyte filtrability; results of a 2-year follow-up study with pentoxifylline. ( Ferrari, E; Solerte, SB, 1985)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's5 (38.46)18.2507
2000's1 (7.69)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baykara, M1
Atabek, ME1
Eklioglu, BS1
Kurtoglu, S1
Lopes de Jesus, CC1
Atallah, AN1
Valente, O1
Moça Trevisani, VF1
Saldan, IR1
Gol'tseva, SV1
Pozza, G1
Cordaro, C1
Carandente, O1
Margonato, A1
Sonkin, PL2
Kelly, LW1
Sinclair, SH1
Hatchell, DL2
Ely, H1
Sebag, J1
Tang, M1
Brown, S1
Sadun, AA1
Charles, MA1
McCarty, MF1
Freedman, SF1
Needham, D1
Rao, KM1
Colombati, S1
Monti, L1
Baggiani, M1
Filippini, F1
Ferrari, E2
Fioravanti, M1
Patti, AL1
Viola, C1
Solerte, SB2

Reviews

1 review available for pentoxifylline and Diabetic Retinopathy

ArticleYear
Pentoxifylline for diabetic retinopathy.
    The Cochrane database of systematic reviews, 2008, Apr-16, Issue:2

    Topics: Diabetic Retinopathy; Humans; Pentoxifylline; Vasodilator Agents

2008

Trials

2 trials available for pentoxifylline and Diabetic Retinopathy

ArticleYear
Pentoxifylline treatment for protecting diabetic retinopaty in children with type 1 diabetes.
    Journal of pediatric endocrinology & metabolism : JPEM, 2013, Volume: 26, Issue:1-2

    Topics: Adolescent; Adult; Age of Onset; Blood Flow Velocity; Carotid Artery, Common; Child; Diabetes Mellit

2013
Pentoxifylline increases retinal capillary blood flow velocity in patients with diabetes.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1993, Volume: 111, Issue:12

    Topics: Administration, Oral; Blood Flow Velocity; Blood Viscosity; Capillaries; Diabetic Retinopathy; Doubl

1993

Other Studies

10 other studies available for pentoxifylline and Diabetic Retinopathy

ArticleYear
[Use of disaggregants in treating diabetic retinopathy].
    Oftalmologicheskii zhurnal, 1984, Issue:7

    Topics: Ascorbic Acid; Aspirin; Calcium Dobesilate; Diabetic Angiopathies; Diabetic Retinopathy; Dipyridamol

1984
[Comparative evaluation of the efficacy of various methods in the treatment of diabetic retinopathies].
    Oftalmologicheskii zhurnal, 1983, Volume: 38, Issue:1

    Topics: Adult; Aged; Blood Viscosity; Diabetic Retinopathy; Female; Humans; Male; Middle Aged; Pentoxifyllin

1983
Study on relationship between erythrocyte filtration and other risk factors in diabetic angiopathy.
    La Ricerca in clinica e in laboratorio, 1981, Volume: 11 Suppl 1

    Topics: Diabetes Mellitus, Type 1; Diabetic Retinopathy; Erythrocytes; Female; Fibrinogen; Humans; Male; Pen

1981
Is pentoxifylline the drug of the decade?
    Journal of the American Academy of Dermatology, 1994, Volume: 30, Issue:4

    Topics: Clinical Trials as Topic; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Human

1994
Effects of pentoxifylline on choroidal blood flow in nonproliferative diabetic retinopathy.
    Angiology, 1994, Volume: 45, Issue:6

    Topics: Adult; Choroid; Diabetic Retinopathy; Female; Humans; Male; Middle Aged; Pentoxifylline; Pilot Proje

1994
Nitric oxide deficiency, leukocyte activation, and resultant ischemia are crucial to the pathogenesis of diabetic retinopathy/neuropathy--preventive potential of antioxidants, essential fatty acids, chromium, ginkgolides, and pentoxifylline.
    Medical hypotheses, 1998, Volume: 50, Issue:5

    Topics: Animals; Antioxidants; Chromium; Diabetic Angiopathies; Diabetic Neuropathies; Diabetic Retinopathy;

1998
Pentoxifylline modulates deformability, F-actin content, and superoxide anion production of polymorphonuclear leukocytes from diabetic cats.
    Experimental eye research, 1992, Volume: 55, Issue:6

    Topics: Actins; Animals; Anions; Cats; Diabetic Retinopathy; Disease Models, Animal; Neutrophils; Pentoxifyl

1992
[Effects of pentoxifylline on the ocular rheographic pulse in diabetic patients].
    La Ricerca in clinica e in laboratorio, 1989, Volume: 19 Suppl 1

    Topics: Adult; Blood Circulation; Diabetic Retinopathy; Female; Humans; Male; Microcirculation; Middle Aged;

1989
Effects of long-term treatment (4 years) with pentoxifylline on haemorheological changes and vascular complications in diabetic patients.
    Pharmatherapeutica, 1987, Volume: 5, Issue:1

    Topics: Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephrop

1987
Diabetic retinal vascular complications and erythrocyte filtrability; results of a 2-year follow-up study with pentoxifylline.
    Pharmatherapeutica, 1985, Volume: 4, Issue:6

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopath

1985