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pentoxifylline and Diabetic Neuropathies

pentoxifylline has been researched along with Diabetic Neuropathies in 18 studies

Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Research Excerpts

ExcerptRelevanceReference
"To test the effectiveness of pentoxifylline as a therapy for diabetic impotence."9.08Trial of pentoxifylline for diabetic impotence. ( Georgitis, WJ; Merenich, JA, 1995)
"To test the effectiveness of pentoxifylline as a therapy for diabetic impotence."5.08Trial of pentoxifylline for diabetic impotence. ( Georgitis, WJ; Merenich, JA, 1995)
"Pentoxifylline has been shown to improve circulation through partially occluded peripheral vessels and has been postulated to be of potential benefit."2.67Pentoxifylline in the treatment of distal diabetic neuropathy. ( Cohen, SM; Mathews, T, 1991)
"Clonidine was administered to 16 subjects at two dosage levels (0."2.67Lack of effect of clonidine and pentoxifylline in short-term therapy of diabetic peripheral neuropathy. ( Chomiak, M; Cohen, KL; Lucibello, FE, 1990)
"Peripheral neuropathy, infection, and peripheral vascular disease can produce serious problems in diabetic patients, particularly in the lower limbs."1.28Lower limb problems in diabetic patients. What are the causes? What are the remedies? ( Bell, DS, 1991)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19903 (16.67)18.7374
1990's10 (55.56)18.2507
2000's3 (16.67)29.6817
2010's0 (0.00)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Dastgheib, M2
Shetab-Boushehri, SV1
Baeeri, M1
Gholami, M1
Karimi, MY1
Hosseini, A2
Falak, R1
Moghaddam, MV1
Hassanzadeh, G1
Safa, M1
Laczy, B1
Cseh, J1
Mohás, M1
Markó, L1
Tamaskó, M1
Koszegi, T1
Molnár, GA1
Wagner, Z1
Wagner, L1
Wittmann, I1
Medvedeva, LA1
Gnezdilov, AV1
Zagorul'ko, OI1
Syrovegin, AV1
Samoĭlova, NV1
Slashchuk, IuI1
Wernicke, JF1
Wang, F1
Pritchett, YL1
Smith, TR1
Raskin, J1
D'Souza, DN1
Iyengar, S1
Chappell, AS1
Georgitis, WJ1
Merenich, JA1
Ely, H1
McDaniel, MD1
McCarty, MF1
Kayal, A1
Rendell, M1
Bamisedun, O1
Sainati, SM1
Cohen, SM1
Mathews, T1
Bell, DS1
Cohen, KL2
Lucibello, FE1
Chomiak, M1
Kalmansohn, RB1
Kalmansohn, RW1
Markham, CH1
Schiff, DL1
Harris, S1
Pierce, WL1
Crowhurst, JA1
Caneva, RG1

Trials

7 trials available for pentoxifylline and Diabetic Neuropathies

ArticleYear
Effects of pentoxifylline and pentosan polysulphate combination therapy on diabetic neuropathy in type 2 diabetes mellitus.
    Acta diabetologica, 2009, Volume: 46, Issue:2

    Topics: Albuminuria; Anticoagulants; Autonomic Nervous System; Blood Pressure; Body Mass Index; Creatinine;

2009
[Neurometabolic therapy of diabetic neuropathy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2006, Volume: 106, Issue:7

    Topics: Adjuvants, Immunologic; Analgesics, Non-Narcotic; Antioxidants; Blood Glucose; Carbamazepine; Diabet

2006
An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain.
    Pain medicine (Malden, Mass.), 2007, Volume: 8, Issue:6

    Topics: Acetaminophen; Amitriptyline; Analgesics; Carbamazepine; Diabetes Complications; Diabetic Neuropathi

2007
Trial of pentoxifylline for diabetic impotence.
    Diabetes care, 1995, Volume: 18, Issue:3

    Topics: Aged; Analysis of Variance; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; E

1995
Pentoxifylline and diabetic neuropathy.
    Diabetes care, 1991, Volume: 14, Issue:10

    Topics: Diabetic Neuropathies; Humans; Pentoxifylline

1991
Pentoxifylline in the treatment of distal diabetic neuropathy.
    Angiology, 1991, Volume: 42, Issue:9

    Topics: Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Electromyography; Humans; Mid

1991
Lack of effect of clonidine and pentoxifylline in short-term therapy of diabetic peripheral neuropathy.
    Diabetes care, 1990, Volume: 13, Issue:10

    Topics: Clonidine; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Drug Evaluation; H

1990

Other Studies

11 other studies available for pentoxifylline and Diabetic Neuropathies

ArticleYear
Rolipram and pentoxifylline combination ameliorates experimental diabetic neuropathy through inhibition of oxidative stress and inflammatory pathways in the dorsal root ganglion neurons.
    Metabolic brain disease, 2022, Volume: 37, Issue:7

    Topics: Adenosine Monophosphate; Animals; Biomarkers; Cyclooxygenase 2; Diabetic Neuropathies; Ganglia, Spin

2022
Rolipram and pentoxifylline combination ameliorates the morphological abnormalities of dorsal root ganglion neurons in experimental diabetic neuropathy by reducing mitochondrial dysfunction and apoptosis.
    Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:11

    Topics: Adenosine Triphosphate; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cytochromes c; Di

2023
Is pentoxifylline the drug of the decade?
    Journal of the American Academy of Dermatology, 1994, Volume: 30, Issue:4

    Topics: Clinical Trials as Topic; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Human

1994
A 52-year-old woman with diabetes and claudication.
    JAMA, 1998, Feb-25, Volume: 279, Issue:8

    Topics: Coronary Disease; Decision Making; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephro

1998
Nitric oxide deficiency, leukocyte activation, and resultant ischemia are crucial to the pathogenesis of diabetic retinopathy/neuropathy--preventive potential of antioxidants, essential fatty acids, chromium, ginkgolides, and pentoxifylline.
    Medical hypotheses, 1998, Volume: 50, Issue:5

    Topics: Animals; Antioxidants; Chromium; Diabetic Angiopathies; Diabetic Neuropathies; Diabetic Retinopathy;

1998
Diabetic peripheral neuropathy.
    The Journal of the Association of Physicians of India, 1992, Volume: 40, Issue:9

    Topics: Diabetic Neuropathies; Humans; Infusions, Intravenous; Pentoxifylline

1992
Skin blood flow and current perception in pentoxifylline-treated diabetic neuropathy.
    Angiology, 1992, Volume: 43, Issue:10

    Topics: Adolescent; Adult; Aged; Diabetic Neuropathies; Drug Evaluation; Electric Stimulation; Humans; Laser

1992
Lower limb problems in diabetic patients. What are the causes? What are the remedies?
    Postgraduate medicine, 1991, Volume: 89, Issue:8

    Topics: Amputation, Surgical; Anti-Bacterial Agents; Clinical Protocols; Debridement; Diabetes Complications

1991
Treatment of diabetic neuropathy with pentoxifylline: case report.
    Angiology, 1988, Volume: 39, Issue:4

    Topics: Aged; Aged, 80 and over; Diabetic Neuropathies; Humans; Male; Pain, Intractable; Pentoxifylline; The

1988
Pentoxifylline and diabetic neuropathy.
    Annals of internal medicine, 1987, Volume: 107, Issue:4

    Topics: Diabetic Neuropathies; Humans; Pentoxifylline; Theobromine

1987
Pentoxifylline. A new drug review and case report.
    Journal of the American Podiatric Medical Association, 1986, Volume: 76, Issue:7

    Topics: Aged; Diabetic Neuropathies; Humans; Intermittent Claudication; Male; Pentoxifylline; Theobromine

1986