Page last updated: 2024-11-02

pentoxifylline and Diabetic Angiopathies

pentoxifylline has been researched along with Diabetic Angiopathies in 37 studies

Diabetic Angiopathies: VASCULAR DISEASES that are associated with DIABETES MELLITUS.

Research Excerpts

ExcerptRelevanceReference
" Cilostazol and pentoxifylline are the only two drugs that have been approved for the treatment of patients with intermittent claudication."9.09Differential effects of cilostazol and pentoxifylline on vascular endothelial growth factor in patients with intermittent claudication. ( Lee, TM; Lee, YT; Su, SF; Tsai, CH; Wang, SS, 2001)
"Among the microvascular complications, diabetic nephropathy is the most frequent cause of end-stage renal disease."6.44Efficacy of pentoxifylline in the management of microalbuminuria in patients with diabetes. ( Guerrero-Romero, F; Rodríguez-Morán, M, 2008)
" Cilostazol and pentoxifylline are the only two drugs that have been approved for the treatment of patients with intermittent claudication."5.09Differential effects of cilostazol and pentoxifylline on vascular endothelial growth factor in patients with intermittent claudication. ( Lee, TM; Lee, YT; Su, SF; Tsai, CH; Wang, SS, 2001)
"The authors analyzed the results of a 2-year study of a course of diabetic microangiopathy on the basis of clinical tests and morphological control over microvessels of skin biopsy specimens from 61 patients with diabetes mellitus, of whom 36 regularly received coronary vasodilators (diamicron, pentoxifylline and dipyridamole)."3.67[Results of a two-year clinico-morphological study of the natural evolution of diabetic microangiopathy and the efficacy of angioprotective therapy]. ( Frolova, AI; Saltykov, BB; Shubina, OI; Velikov, VK, 1987)
"A study was carried out in 127 patients (94 males and 33 females) presenting with arteriosclerosis (88 patients) or diabetic vasculopathy (39 patients) in different stages of severity (Fontaine) to assess the effectiveness and tolerance of treatment with high doses of pentoxifylline."3.67Results of clinical, laboratory and haemorheological investigations of the use of pentoxifylline in high doses. ( Antignani, PL; Bartolo, M; Pacino, G; Saliceti, F; Todini, AR, 1987)
"Pentoxifylline was administered for 6 months."2.76Effectiveness of pentoxifylline on the cross-sectional area of intima media thickness and functions of the common carotid artery in adolescents with type 1 diabetes. ( Atabek, ME; Baykara, M; Kurtoglu, S; Selver, B, 2011)
"Pentoxifylline treatment did not affect the plasma levels of the 3 other variables, von Willebrand factor, 6-keto prostaglandin F1 alpha and thromboxane B2."2.67Platelet activation in diabetic patients with asymptomatic atherosclerosis. ( Imano, E; Kamada, T; Kawamori, R; Kodama, M; Matsushima, H; Nishizawa, H; Watarai, T; Yamasaki, Y, 1994)
"Metformin has unique, intrinsic actions specifically at the level of terminal arterioles, which are completely independent of its antidiabetic effect."2.48Microvascular diseases: is a new era coming? ( Rapin, JR; Wiernsperger, N, 2012)
"Among the microvascular complications, diabetic nephropathy is the most frequent cause of end-stage renal disease."2.44Efficacy of pentoxifylline in the management of microalbuminuria in patients with diabetes. ( Guerrero-Romero, F; Rodríguez-Morán, M, 2008)
"Pentoxifylline was used in the treatment of 90 patients with atherosclerosis-induced chronic peripheral arterial occlusive disease and diabetic vascular disorders in the lower extremities (clinical Fontaine Stages III and IV) for whom surgical reconstructive treatment was not indicated and who had shown inadequate response to previous therapy."1.27Clinical investigation of the effects of pentoxifylline in patients with severe peripheral occlusive vascular disease. ( Seige, K; Sternitzky, R, 1985)
"A long-term trial with oral pentoxifylline ("Trental" 400) in a dosage of 1200 mg per day was carried out in 70 diabetic patients with and without vascular afflictions."1.27Diabetic retinal vascular complications and erythrocyte filtrability; results of a 2-year follow-up study with pentoxifylline. ( Ferrari, E; Solerte, SB, 1985)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199024 (64.86)18.7374
1990's7 (18.92)18.2507
2000's4 (10.81)29.6817
2010's2 (5.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atabek, ME1
Kurtoglu, S1
Selver, B1
Baykara, M1
Wiernsperger, N1
Rapin, JR1
Rodríguez-Morán, M1
Guerrero-Romero, F1
Lipsitz, EC1
Kim, S1
Saldan, IR1
Campbell, RK2
Baker, DE1
Moratti, F1
Cortiana, M1
Taglioretti, D1
Petruzzi, E1
Bucalossi, A1
Corri, S1
Marsilii, A1
Di Noto, C1
Valentini, M1
Sciannameo, F1
Francucci, M1
Tockner, M1
Sassano, L1
Allegra, A1
Isogai, Y1
Mochzuki, K1
Maeda, T1
Spesivtseva, VG1
Kasabian, IN1
Mamaeva, GG1
Kukes, VG1
Fossati, C1
Pampulov, L2
Todorova, S1
Vogralik, VG1
Vogralik, MV1
Runov, GP1
Runova, AA1
Kostrov, AI1
Kawamori, R1
Imano, E1
Watarai, T1
Nishizawa, H1
Matsushima, H1
Kodama, M1
Yamasaki, Y1
Kamada, T1
Colen, LB1
Stevenson, A1
Sidorov, V1
Potparic, Z1
Pacelli, E1
Searles, J1
Lee, S1
Li, L1
Solerte, SB3
Fioravanti, M2
Cerutti, N1
Severgnini, S1
Locatelli, M1
Pezza, N1
Rondanelli, M1
Trecate, L1
Balza, G1
Ferrari, E3
McDaniel, MD1
James, SH1
Meyers, AM1
McCarty, MF1
Bonnardel-Phu, E1
Vicaut, E1
Lee, TM1
Su, SF1
Tsai, CH1
Lee, YT1
Wang, SS1
Kolarov, P1
Veleva, N1
Nobbe, F1
Schubotz, R1
Mühlfellner, O1
Schwartz, RW1
Logan, NM1
Johnson, PJ1
Strodel, WE1
Fine, JG1
Kazmers, A1
Hyde, GL1
Jarcusková, D1
Uhrík, J1
Nazarova, KhI1
Gómez Reyes, D2
Rojas Hidalgo, E2
Velikov, VK1
Shubina, OI1
Saltykov, BB1
Frolova, AI1
Patti, AL1
Viola, C1
Antignani, PL1
Todini, AR1
Saliceti, F1
Pacino, G1
Bartolo, M1
David, JS1
Reichle, RM1
Reichle, FA1
Sternitzky, R1
Seige, K1

Reviews

5 reviews available for pentoxifylline and Diabetic Angiopathies

ArticleYear
Microvascular diseases: is a new era coming?
    Cardiovascular & hematological agents in medicinal chemistry, 2012, Volume: 10, Issue:2

    Topics: Diabetic Angiopathies; Hemorheology; Humans; Metformin; Microcirculation; Microvessels; Myocardial I

2012
Efficacy of pentoxifylline in the management of microalbuminuria in patients with diabetes.
    Current diabetes reviews, 2008, Volume: 4, Issue:1

    Topics: Albuminuria; Animals; Diabetic Angiopathies; Diabetic Nephropathies; Disease Models, Animal; Glomeru

2008
[Therapy of diabetic angiopathies].
    La Clinica terapeutica, 1981, May-31, Volume: 97, Issue:4

    Topics: Acetylcholine; Adrenal Cortex Hormones; Anti-Bacterial Agents; Diabetic Angiopathies; Fibrinolytic A

1981
Clinical update on pentoxifylline therapy for diabetes-induced peripheral vascular disease.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:9

    Topics: Clinical Trials as Topic; Diabetes Complications; Diabetic Angiopathies; Diabetic Foot; Female; Huma

1993
Clinical considerations and treatment of diabetic angiopathy.
    Journal of medicine, 1979, Volume: 10, Issue:5

    Topics: Adult; Arterial Occlusive Diseases; Coronary Disease; Diabetic Angiopathies; Humans; Intermittent Cl

1979

Trials

6 trials available for pentoxifylline and Diabetic Angiopathies

ArticleYear
Effectiveness of pentoxifylline on the cross-sectional area of intima media thickness and functions of the common carotid artery in adolescents with type 1 diabetes.
    Journal of pediatric endocrinology & metabolism : JPEM, 2011, Volume: 24, Issue:11-12

    Topics: Adolescent; Carotid Artery Diseases; Carotid Artery, Common; Carotid Intima-Media Thickness; Child;

2011
[Erythrocyte filterability and treatment with pentoxifylline].
    La Ricerca in clinica e in laboratorio, 1983, Volume: 13 Suppl 3

    Topics: Diabetes Mellitus, Type 1; Diabetic Angiopathies; Erythrocytes; Humans; Middle Aged; Oxygen Consumpt

1983
[Use of trental and complamine in the microcirculatory disorders of diabetes mellitus].
    Sovetskaia meditsina, 1980, Issue:2

    Topics: Adult; Aged; Blood; Clinical Trials as Topic; Diabetic Angiopathies; Diabetic Nephropathies; Female;

1980
Platelet activation in diabetic patients with asymptomatic atherosclerosis.
    Diabetes research and clinical practice, 1994, Volume: 24, Issue:2

    Topics: Aged; Arteriosclerosis; beta-Thromboglobulin; Blood Pressure; Carotid Arteries; Carotid Artery Disea

1994
Differential effects of cilostazol and pentoxifylline on vascular endothelial growth factor in patients with intermittent claudication.
    Clinical science (London, England : 1979), 2001, Volume: 101, Issue:3

    Topics: Aged; Cilostazol; Diabetic Angiopathies; Double-Blind Method; Endothelial Growth Factors; Exercise T

2001
[Therapeutic effect of Trental in diabetic angiopathy].
    Vutreshni bolesti, 1978, Volume: 17, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Diabetic Angiopathies; Drug Evaluation; Electrocardiography;

1978

Other Studies

26 other studies available for pentoxifylline and Diabetic Angiopathies

ArticleYear
Antithrombotic therapy in peripheral arterial disease.
    Cardiology clinics, 2008, Volume: 26, Issue:2

    Topics: Anticoagulants; Aspirin; Atherosclerosis; Cilostazol; Clopidogrel; Comorbidity; Diabetic Angiopathie

2008
[Use of disaggregants in treating diabetic retinopathy].
    Oftalmologicheskii zhurnal, 1984, Issue:7

    Topics: Ascorbic Acid; Aspirin; Calcium Dobesilate; Diabetic Angiopathies; Diabetic Retinopathy; Dipyridamol

1984
Trental: a new medication for diabetic peripheral vascular disorders.
    The Diabetes educator, 1984,Summer, Volume: 10, Issue:2

    Topics: Diabetic Angiopathies; Humans; Pentoxifylline; Theobromine

1984
[Use of erythrocyte filtration in the study of diabetic vasculopathy. Therapeutic efficacy of pentoxifylline].
    La Clinica terapeutica, 1983, Jul-15, Volume: 106, Issue:1

    Topics: Diabetic Angiopathies; Erythrocyte Aggregation; Erythrocytes; Female; Filtration; Humans; Male; Pent

1983
[Use of pentoxifylline in diabetes with intermittent claudication].
    La Ricerca in clinica e in laboratorio, 1983, Volume: 13 Suppl 3

    Topics: Cholesterol; Diabetic Angiopathies; Erythrocytes; Fibrinogen; Glycated Hemoglobin; Humans; Intermitt

1983
Red cell filterability in diabetes.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1981, Volume: 156

    Topics: Adult; Diabetes Mellitus; Diabetic Angiopathies; Erythrocyte Membrane; Erythrocytes; Hemoglobin A; H

1981
[Treatment of diabetic angiopathy with pentoxifylline].
    Vutreshni bolesti, 1982, Volume: 21, Issue:3

    Topics: Adult; Aged; Amputation, Surgical; Diabetic Angiopathies; Female; Humans; Leg; Male; Middle Aged; Pe

1982
[Trental treatment of microcirculatory disorders in diabetes mellitus and arteriosclerosis].
    Klinicheskaia meditsina, 1982, Volume: 60, Issue:10

    Topics: Adolescent; Adult; Aged; Arteriosclerosis; Blood Viscosity; Diabetic Angiopathies; Drug Evaluation;

1982
Microvascular anastomotic thrombosis in experimental diabetes mellitus.
    Plastic and reconstructive surgery, 1997, Volume: 99, Issue:1

    Topics: Anastomosis, Surgical; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Angiopathie

1997
Retrospective analysis of long-term hemorheologic effects of pentoxifylline in diabetic patients with angiopathic complications.
    Acta diabetologica, 1997, Volume: 34, Issue:2

    Topics: Adult; Aged; Albuminuria; Blood Pressure; Blood Viscosity; Diabetic Angiopathies; Female; Fibrinogen

1997
A 52-year-old woman with diabetes and claudication.
    JAMA, 1998, Feb-25, Volume: 279, Issue:8

    Topics: Coronary Disease; Decision Making; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephro

1998
Microangiopathic hemolytic anemia as a complication of diabetes mellitus.
    The American journal of the medical sciences, 1998, Volume: 315, Issue:3

    Topics: Anemia, Hemolytic; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Erythro

1998
Nitric oxide deficiency, leukocyte activation, and resultant ischemia are crucial to the pathogenesis of diabetic retinopathy/neuropathy--preventive potential of antioxidants, essential fatty acids, chromium, ginkgolides, and pentoxifylline.
    Medical hypotheses, 1998, Volume: 50, Issue:5

    Topics: Animals; Antioxidants; Chromium; Diabetic Angiopathies; Diabetic Neuropathies; Diabetic Retinopathy;

1998
[Role of oxidative stress in permeability changes observed in the microcirculation of diabetic rats in vivo].
    Journal des maladies vasculaires, 2000, Volume: 25, Issue:2

    Topics: Animals; Capillary Permeability; Catalase; Diabetes Mellitus, Experimental; Diabetic Angiopathies; D

2000
The effect of pentoxifylline on erythrocyte deformability and on phosphatide fatty acid distribution in the erythrocyte membrane.
    Current medical research and opinion, 1977, Volume: 4, Issue:9

    Topics: Aged; Diabetic Angiopathies; Erythrocyte Membrane; Erythrocytes; Fatty Acids; Female; Humans; Male;

1977
Pentoxifylline increases extremity blood flow in diabetic atherosclerotic patients.
    Archives of surgery (Chicago, Ill. : 1960), 1989, Volume: 124, Issue:4

    Topics: Arteries; Arteriosclerosis; Diabetes Mellitus; Diabetic Angiopathies; Exercise Test; Female; Humans;

1989
[Evaluation of thermal conductivity and skin temperature in the treatment of leg ulcers].
    Bratislavske lekarske listy, 1988, Volume: 89, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Diabetic Angiopathies; Female; Humans; Leg; Leg Ul

1988
[Effect of the long-term prophylactic use of trental on cerebral blood flow in diabetics].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:9

    Topics: Adult; Cerebrovascular Disorders; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Diabet

1988
[Therapeutic results with xanthine derivatives in the intermittent claudication syndrome in diabetic patients].
    Revista clinica espanola, 1988, Volume: 182, Issue:1

    Topics: Adult; Aged; Diabetic Angiopathies; Drug Therapy, Combination; Female; Humans; Intermittent Claudica

1988
[Results of a two-year clinico-morphological study of the natural evolution of diabetic microangiopathy and the efficacy of angioprotective therapy].
    Terapevticheskii arkhiv, 1987, Volume: 59, Issue:11

    Topics: Adolescent; Adult; Aged; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Dipyridam

1987
Effects of long-term treatment (4 years) with pentoxifylline on haemorheological changes and vascular complications in diabetic patients.
    Pharmatherapeutica, 1987, Volume: 5, Issue:1

    Topics: Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephrop

1987
Results of clinical, laboratory and haemorheological investigations of the use of pentoxifylline in high doses.
    Pharmatherapeutica, 1987, Volume: 5, Issue:1

    Topics: Aged; Arteriosclerosis; Blood Pressure; Diabetic Angiopathies; Erythrocyte Deformability; Female; Hu

1987
[Xanthinic derivatives in the treatment of intermittent claudication syndrome in diabetic patients].
    Revista clinica espanola, 1986, Volume: 179, Issue:3

    Topics: Diabetes Complications; Diabetic Angiopathies; Drug Therapy, Combination; Humans; Intermittent Claud

1986
Altered low density lipoproteins in peripheral vascular disease patients.
    The Journal of surgical research, 1986, Volume: 41, Issue:5

    Topics: Aged; Arterial Occlusive Diseases; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetic Angiopathies

1986
Clinical investigation of the effects of pentoxifylline in patients with severe peripheral occlusive vascular disease.
    Current medical research and opinion, 1985, Volume: 9, Issue:9

    Topics: Adult; Aged; Arterial Occlusive Diseases; Arteriosclerosis; Diabetes Mellitus, Type 1; Diabetes Mell

1985
Diabetic retinal vascular complications and erythrocyte filtrability; results of a 2-year follow-up study with pentoxifylline.
    Pharmatherapeutica, 1985, Volume: 4, Issue:6

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopath

1985