pentoxifylline has been researched along with Cystic Fibrosis in 5 studies
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To test this hypothesis, we studied pentoxifylline, a compound that inhibits tumor necrosis factor alpha transcription and its stimulatory effect on polymorphonuclear neutrophils, in patients with CF who had chronic Pseudomonas bronchitis." | 9.07 | Effects of pentoxifylline on sputum neutrophil elastase and pulmonary function in patients with cystic fibrosis: preliminary observations. ( Aronoff, SC; Carpenter, LS; Novick, WJ; Quinn, FJ, 1994) |
| " To test this hypothesis, we studied pentoxifylline, a compound that inhibits tumor necrosis factor alpha transcription and its stimulatory effect on polymorphonuclear neutrophils, in patients with CF who had chronic Pseudomonas bronchitis." | 5.07 | Effects of pentoxifylline on sputum neutrophil elastase and pulmonary function in patients with cystic fibrosis: preliminary observations. ( Aronoff, SC; Carpenter, LS; Novick, WJ; Quinn, FJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chung, WJ | 1 |
| Goeckeler-Fried, JL | 1 |
| Havasi, V | 1 |
| Chiang, A | 1 |
| Rowe, SM | 1 |
| Plyler, ZE | 1 |
| Hong, JS | 1 |
| Mazur, M | 1 |
| Piazza, GA | 1 |
| Keeton, AB | 1 |
| White, EL | 1 |
| Rasmussen, L | 1 |
| Weissman, AM | 1 |
| Denny, RA | 1 |
| Brodsky, JL | 1 |
| Sorscher, EJ | 1 |
| Prescott, WA | 1 |
| Johnson, CE | 1 |
| Aronoff, SC | 1 |
| Quinn, FJ | 1 |
| Carpenter, LS | 1 |
| Novick, WJ | 1 |
| Konstan, MW | 1 |
| Thorne, PS | 1 |
| McCray, PB | 1 |
| Howe, TS | 1 |
| O'Neill, MA | 1 |
2 reviews available for pentoxifylline and Cystic Fibrosis
| Article | Year |
|---|---|
Antiinflammatory therapies for cystic fibrosis: past, present, and future.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adult; Anti-Inflammatory Agents; Azithro | 2005 |
Treatment of airway inflammation in cystic fibrosis.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Age Factors; Anti-Inflammatory Agents; Anti-Inf | 1996 |
1 trial available for pentoxifylline and Cystic Fibrosis
| Article | Year |
|---|---|
Effects of pentoxifylline on sputum neutrophil elastase and pulmonary function in patients with cystic fibrosis: preliminary observations.
Topics: Administration, Oral; Adolescent; Adult; Bronchitis; Bronchoalveolar Lavage Fluid; Child; Chronic Di | 1994 |
2 other studies available for pentoxifylline and Cystic Fibrosis
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regu | 2016 |
Early-onset inflammatory responses in vivo to adenoviral vectors in the presence or absence of lipopolysaccharide-induced inflammation.
Topics: Adenoviridae; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalv | 1999 |