Page last updated: 2024-11-02

pentoxifylline and Colorectal Neoplasms

pentoxifylline has been researched along with Colorectal Neoplasms in 4 studies

Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.

Research Excerpts

ExcerptRelevanceReference
" We investigated the hypothesis that preincisional IV pentoxifylline (PTX) treatment could attenuate the release of proinflammatory (tumor necrosis factor, interleukin (IL)-1beta, IL-6, and IL-8) and antiinflammatory (IL-1 receptor antagonist) cytokines in patients who underwent elective colorectal cancer surgery."9.11Preincisional intravenous pentoxifylline attenuating perioperative cytokine response, reducing morphine consumption, and improving recovery of bowel function in patients undergoing colorectal cancer surgery. ( Borel, CO; Chao, PC; Lu, CH; Wong, CS; Wu, CT; Yang, CP; Yeh, CC, 2004)
" We investigated the hypothesis that preincisional IV pentoxifylline (PTX) treatment could attenuate the release of proinflammatory (tumor necrosis factor, interleukin (IL)-1beta, IL-6, and IL-8) and antiinflammatory (IL-1 receptor antagonist) cytokines in patients who underwent elective colorectal cancer surgery."5.11Preincisional intravenous pentoxifylline attenuating perioperative cytokine response, reducing morphine consumption, and improving recovery of bowel function in patients undergoing colorectal cancer surgery. ( Borel, CO; Chao, PC; Lu, CH; Wong, CS; Wu, CT; Yang, CP; Yeh, CC, 2004)
"Patients with liver metastases from colorectal carcinoma who were scheduled for local ablation by radiotherapy (image-guided high-dose-rate interstitial brachytherapy) were prospectively randomized to receive PTX, UDCA and LMWH for 8 weeks (treatment) or no medication (control)."2.79Prospective randomized trial of enoxaparin, pentoxifylline and ursodeoxycholic acid for prevention of radiation-induced liver toxicity. ( Damm, R; Gademann, G; Hass, P; Kropf, S; Mohnike, K; Pech, M; Ricke, J; Sangro, B; Seidensticker, M; Seidensticker, R; Wust, P, 2014)
"RNA sequencing of primary colorectal cancer specimens vs adjacent liver tissue vs synchronous and asynchronous liver metastases."1.91Interrogating colorectal cancer metastasis to liver: a search for clinically viable compounds and mechanistic insights in colorectal cancer Patient Derived Organoids. ( Blandino, G; Canu, V; Caricato, M; Cioce, M; Crescenzi, A; Diodoro, MG; Donzelli, S; Fanciulli, M; Fazio, VM; Fumagalli, MR; Goeman, F; Grazi, GL; La Porta, C; Levrero, M; Morrone, A; Orlandi, G; Palcau, AC; Pulito, C; Rutigliano, D; Sacconi, A; Strano, S; Verri, M; Zapperi, S, 2023)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Cioce, M1
Fumagalli, MR1
Donzelli, S1
Goeman, F1
Canu, V1
Rutigliano, D1
Orlandi, G1
Sacconi, A1
Pulito, C1
Palcau, AC1
Fanciulli, M1
Morrone, A1
Diodoro, MG1
Caricato, M1
Crescenzi, A1
Verri, M1
Fazio, VM1
Zapperi, S1
Levrero, M1
Strano, S1
Grazi, GL1
La Porta, C1
Blandino, G1
Seidensticker, M1
Seidensticker, R1
Damm, R1
Mohnike, K1
Pech, M1
Sangro, B1
Hass, P1
Wust, P1
Kropf, S1
Gademann, G1
Ricke, J1
Lu, CH1
Chao, PC1
Borel, CO1
Yang, CP1
Yeh, CC1
Wong, CS1
Wu, CT1
Tuckey, JA1
Parry, BR1
McCall, JL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Preventive Effect of Enoxaparin, Pentoxifylline and Ursodeoxycholic Acid to Radiation Induced Liver Toxicity After Brachytherapy of Liver Metastases From Colorectal Carcinoma, Assessed in a Prospective Randomised Trial[NCT01149304]Phase 222 participants (Actual)Interventional2009-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for pentoxifylline and Colorectal Neoplasms

ArticleYear
Prospective randomized trial of enoxaparin, pentoxifylline and ursodeoxycholic acid for prevention of radiation-induced liver toxicity.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Aged; Aged, 80 and over; Brachytherapy; Colorectal Neoplasms; Enoxaparin; Female; Humans; Liver Neop

2014
Preincisional intravenous pentoxifylline attenuating perioperative cytokine response, reducing morphine consumption, and improving recovery of bowel function in patients undergoing colorectal cancer surgery.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Gener

2004
Pentoxifylline and wellbeing in cancer.
    Lancet (London, England), 1993, Sep-04, Volume: 342, Issue:8871

    Topics: Colorectal Neoplasms; Fatigue; Gastrointestinal Neoplasms; Humans; Pentoxifylline; Quality of Life;

1993

Other Studies

1 other study available for pentoxifylline and Colorectal Neoplasms

ArticleYear
Interrogating colorectal cancer metastasis to liver: a search for clinically viable compounds and mechanistic insights in colorectal cancer Patient Derived Organoids.
    Journal of experimental & clinical cancer research : CR, 2023, Jul-17, Volume: 42, Issue:1

    Topics: Colorectal Neoplasms; Fluorouracil; Humans; Interleukin-6; Liver Neoplasms; Organoids; Pentoxifyllin

2023