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pentoxifylline and Colitis

pentoxifylline has been researched along with Colitis in 7 studies

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"This study was designed to identify the effect of pentoxifylline on trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats."7.85Pentoxifylline attenuates mucosal damage in an experimental model of rat colitis by modulating tissue biomarkers of inflammation, oxidative stress, and fibrosis. ( Arhan, M; Ekinci, Ö; Erdal, H; G Dumlu, Ş; Gül Utku, Ö; Ibiş, M; Karatay, E; Önal, İK; Yilmaz Demirtaş, C, 2017)
"The effect of acute pentoxifylline treatment in an experimental model of colitis was assessed using the trinitrobenzene sulphonic acid (TNBS)-induced rat model of colitis."7.69Effect of acute pentoxifylline treatment in an experimental model of colitis. ( Davey, K; Peterson, TC, 1997)
"Pentoxifylline and M-1 treatment significantly attenuated colon damage and inflammation in TNBS-colitis (P<0."5.37The effect of pentoxifylline and its metabolite-1 on inflammation and fibrosis in the TNBS model of colitis. ( Peterson, MR; Peterson, TC; Raoul, JM, 2011)
"Colitis was induced by rectal administration of ethanol and trinitrobenzene sulfonic acid in rats."5.31Lisofylline and lysophospholipids ameliorate experimental colitis in rats. ( Dignass, AU; Gerken, G; Rath, H; Sturm, A; Sudermann, T; Zeeh, J, 2002)
"Colitis was induced by the feeding of 3% DSS for three cycles."5.30Combination therapy of pentoxifylline and TNFalpha monoclonal antibody in dextran sulphate-induced mouse colitis. ( Cooper, HS; Meyer, C; Meyer, CJ; Murthy, NS; Murthy, S; Yoshitake, H, 1999)
"This study was designed to identify the effect of pentoxifylline on trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats."3.85Pentoxifylline attenuates mucosal damage in an experimental model of rat colitis by modulating tissue biomarkers of inflammation, oxidative stress, and fibrosis. ( Arhan, M; Ekinci, Ö; Erdal, H; G Dumlu, Ş; Gül Utku, Ö; Ibiş, M; Karatay, E; Önal, İK; Yilmaz Demirtaş, C, 2017)
" Here we assessed the ability of PDE inhibitors to modulate colitis by exposing mice to 4% (w/v) dextran sulfate sodium (DSS) drinking water for 5 days with or without rolipram, an inhibitor of PDE type 4, or the nonselective PDE inhibitor, pentoxifylline (both at 5 mg/kg, i."3.70Dextran sulfate sodium-induced colonic histopathology, but not altered epithelial ion transport, is reduced by inhibition of phosphodiesterase activity. ( Diaz-Granados, N; Howe, K; Lu, J; McKay, DM, 2000)
"The effect of acute pentoxifylline treatment in an experimental model of colitis was assessed using the trinitrobenzene sulphonic acid (TNBS)-induced rat model of colitis."3.69Effect of acute pentoxifylline treatment in an experimental model of colitis. ( Davey, K; Peterson, TC, 1997)
"Pentoxifylline and M-1 treatment significantly attenuated colon damage and inflammation in TNBS-colitis (P<0."1.37The effect of pentoxifylline and its metabolite-1 on inflammation and fibrosis in the TNBS model of colitis. ( Peterson, MR; Peterson, TC; Raoul, JM, 2011)
"Colitis was induced by rectal administration of ethanol and trinitrobenzene sulfonic acid in rats."1.31Lisofylline and lysophospholipids ameliorate experimental colitis in rats. ( Dignass, AU; Gerken, G; Rath, H; Sturm, A; Sudermann, T; Zeeh, J, 2002)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karatay, E1
Gül Utku, Ö1
Erdal, H1
Arhan, M1
Önal, İK1
Ibiş, M1
Ekinci, Ö1
Yilmaz Demirtaş, C1
G Dumlu, Ş1
Peterson, TC2
Peterson, MR1
Raoul, JM1
Sturm, A1
Zeeh, J1
Sudermann, T1
Rath, H1
Gerken, G1
Dignass, AU1
Bauditz, J1
Rückert, Y1
Raedler, A1
Nikolaus, S1
Lochs, H1
Schreiber, S1
Davey, K1
Murthy, S1
Cooper, HS1
Yoshitake, H1
Meyer, C1
Meyer, CJ1
Murthy, NS1
Diaz-Granados, N1
Howe, K1
Lu, J1
McKay, DM1

Other Studies

7 other studies available for pentoxifylline and Colitis

ArticleYear
Pentoxifylline attenuates mucosal damage in an experimental model of rat colitis by modulating tissue biomarkers of inflammation, oxidative stress, and fibrosis.
    Turkish journal of medical sciences, 2017, Feb-27, Volume: 47, Issue:1

    Topics: Animals; Biomarkers; Colitis; Disease Models, Animal; Female; Fibrosis; Inflammation; Intestinal Muc

2017
The effect of pentoxifylline and its metabolite-1 on inflammation and fibrosis in the TNBS model of colitis.
    European journal of pharmacology, 2011, Jul-15, Volume: 662, Issue:1-3

    Topics: Animals; Colitis; Collagen Type I; Colon; Disease Models, Animal; Female; Fibrosis; Inflammation; In

2011
Lisofylline and lysophospholipids ameliorate experimental colitis in rats.
    Digestion, 2002, Volume: 66, Issue:1

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Ethanol; Lysopho

2002
Tumour necrosis factor inhibition by oxpentifylline and intestinal inflammation in Crohn's disease.
    Lancet (London, England), 1995, Jun-03, Volume: 345, Issue:8962

    Topics: Adult; Colitis; Crohn Disease; Female; Humans; Male; Pentoxifylline; Tumor Necrosis Factor-alpha

1995
Effect of acute pentoxifylline treatment in an experimental model of colitis.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:3

    Topics: Animals; Colitis; Collagen; Colon; Disease Models, Animal; Male; Pentoxifylline; Phosphodiesterase I

1997
Combination therapy of pentoxifylline and TNFalpha monoclonal antibody in dextran sulphate-induced mouse colitis.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Colitis; Dextran Sulfate; Female; Immunoglobulin G; Mice; Pentoxify

1999
Dextran sulfate sodium-induced colonic histopathology, but not altered epithelial ion transport, is reduced by inhibition of phosphodiesterase activity.
    The American journal of pathology, 2000, Volume: 156, Issue:6

    Topics: Animals; Biological Transport; Colitis; Colon; Cytokines; Dextran Sulfate; Epithelium; Intestinal Mu

2000