Page last updated: 2024-11-02

pentoxifylline and Chronic Disease

pentoxifylline has been researched along with Chronic Disease in 98 studies

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"Pentoxifylline added to losartan therapy for 1 year decreased proteinuria in patients with CKD stages 3 to 5."9.13Effect of pentoxifylline in addition to losartan on proteinuria and GFR in CKD: a 12-month randomized trial. ( Chen, YM; Chiang, WC; Lin, SL; Tsai, TJ; Wu, KD, 2008)
"The study fails to demonstrate efficacy of dl-alpha tocopheryl acetate plus pentoxifylline in patients with arm lymphoedema following axillary surgery and lymphatic radiotherapy, nor does it suggest any benefits of these drugs in radiation-induced induration (fibrosis) in the breast, chest wall, pectoral fold, axilla or supraclavicular fossa."9.11Double-blind placebo-controlled randomised trial of vitamin E and pentoxifylline in patients with chronic arm lymphoedema and fibrosis after surgery and radiotherapy for breast cancer. ( Cornes, P; Earl, J; Gothard, L; Hall, E; MacLaren, J; Mortimer, P; Peacock, J; Peckitt, C; Woods, M; Yarnold, J, 2004)
" To test this hypothesis, we studied pentoxifylline, a compound that inhibits tumor necrosis factor alpha transcription and its stimulatory effect on polymorphonuclear neutrophils, in patients with CF who had chronic Pseudomonas bronchitis."9.07Effects of pentoxifylline on sputum neutrophil elastase and pulmonary function in patients with cystic fibrosis: preliminary observations. ( Aronoff, SC; Carpenter, LS; Novick, WJ; Quinn, FJ, 1994)
"A double-blind, placebo-controlled study was carried out in 12 patients suffering from chronic venous insufficiency and persistent leg ulcers to assess the efficacy of pentoxifylline treatment as an adjunct to compression bandaging in the conservative management of venous leg ulcers."9.07Pentoxifylline in the treatment of venous leg ulcers. ( Barbarino, C, 1992)
"Ten patients with Stage II chronic arterial occlusive disease (intermittent claudication) took part in a randomized, intraindividual crossover study involving acute intravenous administration of 200 mg pentoxifylline or physiological saline solution (placebo)."9.06Influence of pentoxifylline on muscle tissue oxygen tension (pO2) of patients with intermittent claudication before and after pedal ergometer exercise. ( Ehrly, AM; Saeger-Lorenz, K, 1987)
"The effects of pentoxifylline on intermittent claudication were evaluated at a dose of 1200 mg/day in an open-label twelve-week study on geriatric patients with chronic occlusive arterial disease (COAD)."9.06Efficacy and safety of pentoxifylline in geriatric patients with intermittent claudication. ( Cobert, BL; Cohn, JB; Crowder, JE; Hryniewicki, SW; Morgan, DL; Piccirillo, RT; Savitsky, JP; Slywka, J; Wilcox, CS, 1989)
"To assess the effects of pentoxifylline, which has anti-inflammatory effects, in subfertile, premenopausal women for the management of endometriosis."8.88Pentoxifylline for endometriosis. ( Clarke, J; Li, Y; Lu, D; Shi, G; Song, H, 2012)
"The influence of vinpocetine, pentoxifylline and enalapril on endothelium functions has been studied in a group of in 172 patients with chronic brain ischemia."7.77[Endothelium-protective effects of vinpocetine, pentoxifylline and enalapril in patients with chronic brain ischemia]. ( Alifirova, VM; Vaizova, OE; Vengerovsky, AI, 2011)
"The short-term effects of pentoxifylline (PTX) on granulomatous lesions during Schistosoma mansoni infection in Swiss mice were evaluated."7.76Effects of pentoxifylline during Schistosoma mansoni infection in Swiss mice: an analysis of worm burden, fecundity and liver histopathology. ( Freitas, RM; Mati, VL; Melo, AL, 2010)
"A 58-year-old black man with leg ulcers of 43 years duration responded to pentoxifylline 400 mg tid in 8 months."7.68Treatment of sickle cell leg ulcers with pentoxifylline. ( Frost, ML; Treadwell, P, 1990)
"Decreasing proteinuria is the mainstay of therapy in order to delay the progression of CKD."6.47A review of the potential benefits of pentoxifylline in diabetic and non-diabetic proteinuria. ( Abdollahi, M; Badri, S; Dashti-Khavidaki, S; Lessan-Pezeshki, M, 2011)
"Pentoxifylline is a useful inhibitor of TNF-alpha production, thus resembling anti-inflammatory corticosteroids."5.32Anti-TNF-alpha therapy for chronic inflammation: reconsidering pentoxifylline as an alternative to therapeutic protein drugs. ( Whitehouse, MW, 2004)
"Treatment with pentoxifylline was effective."5.29Chronic balanitis with palisading granuloma: an atypical genital localization of necrobiosis lipoidica responsive to pentoxifylline. ( España, A; Quintanilla, E; Redondo, P; Robledo, A; Sánchez-Yus, E; Serna, MJ, 1994)
"Pentoxifylline added to losartan therapy for 1 year decreased proteinuria in patients with CKD stages 3 to 5."5.13Effect of pentoxifylline in addition to losartan on proteinuria and GFR in CKD: a 12-month randomized trial. ( Chen, YM; Chiang, WC; Lin, SL; Tsai, TJ; Wu, KD, 2008)
"The study fails to demonstrate efficacy of dl-alpha tocopheryl acetate plus pentoxifylline in patients with arm lymphoedema following axillary surgery and lymphatic radiotherapy, nor does it suggest any benefits of these drugs in radiation-induced induration (fibrosis) in the breast, chest wall, pectoral fold, axilla or supraclavicular fossa."5.11Double-blind placebo-controlled randomised trial of vitamin E and pentoxifylline in patients with chronic arm lymphoedema and fibrosis after surgery and radiotherapy for breast cancer. ( Cornes, P; Earl, J; Gothard, L; Hall, E; MacLaren, J; Mortimer, P; Peacock, J; Peckitt, C; Woods, M; Yarnold, J, 2004)
" To test this hypothesis, we studied pentoxifylline, a compound that inhibits tumor necrosis factor alpha transcription and its stimulatory effect on polymorphonuclear neutrophils, in patients with CF who had chronic Pseudomonas bronchitis."5.07Effects of pentoxifylline on sputum neutrophil elastase and pulmonary function in patients with cystic fibrosis: preliminary observations. ( Aronoff, SC; Carpenter, LS; Novick, WJ; Quinn, FJ, 1994)
"A double-blind, placebo-controlled study was carried out in 12 patients suffering from chronic venous insufficiency and persistent leg ulcers to assess the efficacy of pentoxifylline treatment as an adjunct to compression bandaging in the conservative management of venous leg ulcers."5.07Pentoxifylline in the treatment of venous leg ulcers. ( Barbarino, C, 1992)
"The effects of pentoxifylline on intermittent claudication were evaluated at a dose of 1200 mg/day in an open-label twelve-week study on geriatric patients with chronic occlusive arterial disease (COAD)."5.06Efficacy and safety of pentoxifylline in geriatric patients with intermittent claudication. ( Cobert, BL; Cohn, JB; Crowder, JE; Hryniewicki, SW; Morgan, DL; Piccirillo, RT; Savitsky, JP; Slywka, J; Wilcox, CS, 1989)
"Ten patients with Stage II chronic arterial occlusive disease (intermittent claudication) took part in a randomized, intraindividual crossover study involving acute intravenous administration of 200 mg pentoxifylline or physiological saline solution (placebo)."5.06Influence of pentoxifylline on muscle tissue oxygen tension (pO2) of patients with intermittent claudication before and after pedal ergometer exercise. ( Ehrly, AM; Saeger-Lorenz, K, 1987)
"To assess the effects of pentoxifylline, which has anti-inflammatory effects, in subfertile, premenopausal women for the management of endometriosis."4.88Pentoxifylline for endometriosis. ( Clarke, J; Li, Y; Lu, D; Shi, G; Song, H, 2012)
"The influence of vinpocetine, pentoxifylline and enalapril on endothelium functions has been studied in a group of in 172 patients with chronic brain ischemia."3.77[Endothelium-protective effects of vinpocetine, pentoxifylline and enalapril in patients with chronic brain ischemia]. ( Alifirova, VM; Vaizova, OE; Vengerovsky, AI, 2011)
"The short-term effects of pentoxifylline (PTX) on granulomatous lesions during Schistosoma mansoni infection in Swiss mice were evaluated."3.76Effects of pentoxifylline during Schistosoma mansoni infection in Swiss mice: an analysis of worm burden, fecundity and liver histopathology. ( Freitas, RM; Mati, VL; Melo, AL, 2010)
"From 2001 to 2006, we performed a retrospective study of patients suffering from chronic unilateral or bilateral tinnitus that was previously ineffectively treated by oral drugs [betahistine (Betaserc), extract of Ginkgo biloba (EGb 761), tanakan (Tebokan), and cinnarizine-dimenhydrinate (Arlevert), singly or in combination]."3.74Multimodal therapy for chronic tinnitus. ( Achiemere, G; Alpini, D; Hahn, A; Klement, V; Radkova, L; Strouhal, J, 2008)
"We investigated the ability of pentoxifylline, a drug with hemorheological actions known to block tumor necrosis factor-alpha (TNF-alpha) release, to modulate whole-body protein kinetics in undialyzed patients with chronic uremia."3.71Pentoxifylline acutely reduces protein catabolism in chronically uremic patients. ( Biolo, G; Bosutti, A; Ciocchi, B; Guarnieri, G; Situlin, R; Toigo, G, 2002)
"A 58-year-old black man with leg ulcers of 43 years duration responded to pentoxifylline 400 mg tid in 8 months."3.68Treatment of sickle cell leg ulcers with pentoxifylline. ( Frost, ML; Treadwell, P, 1990)
"The effect of combined use of pentoxifylline and solcoseryl was studied in 35 patients with chronic pancreatitis."3.67[Trial of the combined use of trental and solcoseryl in treating patients with chronic pancreatitis]. ( Solov'eva, NE; Trusov, VV; Vakhrushev, IaM, 1988)
"Treatment with pentoxifylline reduced circulating IL-6 (6."2.75Pentoxifylline improves haemoglobin and interleukin-6 levels in chronic kidney disease. ( Ferrari, P; Mallon, D; Olynyk, JK; Trinder, D, 2010)
"Proteinuria was not different between the pentoxifylline and placebo groups at baseline, 6 months, or 1 year."2.74Effect of pentoxifylline on GFR decline in CKD: a pilot, double-blind, randomized, placebo-controlled trial. ( Aboudara, MC; Cushner, HM; Olson, SW; Perkins, RM; Uy, AL; Yuan, CM, 2009)
"Sixteen Crohn's disease patients received oxpentifylline 400 mg four times a day in a four week open label study."2.68Treatment with tumour necrosis factor inhibitor oxpentifylline does not improve corticosteroid dependent chronic active Crohn's disease. ( Bauditz, J; Haemling, J; Lochs, H; Ortner, M; Raedler, A; Schreiber, S, 1997)
"Decreasing proteinuria is the mainstay of therapy in order to delay the progression of CKD."2.47A review of the potential benefits of pentoxifylline in diabetic and non-diabetic proteinuria. ( Abdollahi, M; Badri, S; Dashti-Khavidaki, S; Lessan-Pezeshki, M, 2011)
"Radiation enteritis is a severe problem in patients receiving irradiation of the abdomen or pelvis in the course of cancer treatment."2.44Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review. ( Böcker, U; Singer, MV; Wenz, F; Zimmerer, T, 2008)
"Venous ulcers affect approximately 1% of the world's population, increasing healthcare expenditures and decreasing quality of life."2.43Venous ulcers: pathophysiology and treatment options. ( Eaglstein, WH; Falabella, A; Kirsner, RS; Trent, JT, 2005)
"Classification of tinnitus is oriented to the duration of symptoms and their severity, the latter taking into account the victim's distress both at work and during leisure time."2.42[Tinnitus--classification, causes, diagnosis, treatment and prognosis]. ( Koester, M; Storck, C; Zorowka, P, 2004)
"Chronic venous insufficiency is frequent and burdened with potentially serious consequences."2.38[Conservative therapy of chronic venous insufficiency]. ( Ernst, E; Saradeth, T, 1992)
" We investigated the effect of chronic administration (2 weeks) of imipramine (20 mg/kg/day) and pentoxifylline (50 mg/kg/day) on behavioral, aortic histological abnormalities, and level of circulating endothelial progenitor cells (CEPCs) in peripheral blood of male Wistar rats exposed to chronic mild stress (CMS) and high-fat diet."1.51Pentoxifylline ameliorates chronic stress/high-fat diet-induced vascular wall disease: the role of circulating endothelial progenitor cells. ( Abdel-Tawab, AM; Aboul-Fotouh, S; Farrag, KA; Habib, MZ; Labib, JMW; Mekawy, MAEA, 2019)
"Pyoderma gangrenosum is most commonly treated with immunosuppressants or anti-inflammatory agents and is often worsened by surgical procedures due to the presence of pathergy."1.48Improvement of Ulcerations in Treatment-Resistant Chronic Scarring in a Patient with Pyoderma Gangrenosum After Improving Vascular Insufficiency, Gently Removing Necrotic Debris, and Decreasing Wound Fluid. ( Gordon, C; Hizon, BJ; Mota, JA; Nahm, WJ; Rojas, S, 2018)
"A method for the treatment of chronic sensorineural hearing loss (CSNHL) is proposed that includes administration of trental followed by intravenous laser irradiation of blood (IVLBI)."1.37[Intravenous laser irradiation of blood for the combined treatment of patients presenting with chronic sensorineural hearing loss]. ( , 2011)
"Pentoxifylline is a useful inhibitor of TNF-alpha production, thus resembling anti-inflammatory corticosteroids."1.32Anti-TNF-alpha therapy for chronic inflammation: reconsidering pentoxifylline as an alternative to therapeutic protein drugs. ( Whitehouse, MW, 2004)
"Treatment with pentoxifylline was effective."1.29Chronic balanitis with palisading granuloma: an atypical genital localization of necrobiosis lipoidica responsive to pentoxifylline. ( España, A; Quintanilla, E; Redondo, P; Robledo, A; Sánchez-Yus, E; Serna, MJ, 1994)
"Oral treatment with pentoxifylline 400 mg t."1.28Intractable chronic furunculosis: prevention of recurrences with pentoxifylline. ( Wahba-Yahav, AV, 1992)
"Pentoxifylline was administered orally at a dose of 1200 mg/day over a period of 30 days (eight patients) or by intravenous infusion of 100 ml saline containing 400 mg of the drug in 1 hour (three patients)."1.26Effect of pentoxifylline on cerebral blood flow in patients with chronic cerebrovascular disease. ( Battistini, N; Nardini, M; Passero, S, 1981)

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-199029 (29.59)18.7374
1990's23 (23.47)18.2507
2000's33 (33.67)29.6817
2010's13 (13.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Procházková, K1
Šejna, I1
Skutil, J1
Hahn, A2
Nahm, WJ1
Mota, JA1
Rojas, S1
Hizon, BJ1
Gordon, C1
Labib, JMW1
Aboul-Fotouh, S1
Habib, MZ1
Mekawy, MAEA1
Farrag, KA1
Abdel-Tawab, AM1
Radkova, L1
Achiemere, G1
Klement, V1
Alpini, D1
Strouhal, J1
Lin, SL1
Chen, YM1
Chiang, WC1
Wu, KD1
Tsai, TJ1
Renke, M1
Rutkowski, P1
Tylicki, L1
Zietkiewicz, M1
Larczyński, W1
Rutkowski, B1
Fu, M1
Shaw, SM1
Shah, MK1
Williams, SG1
Fildes, JE1
Perkins, RM1
Aboudara, MC1
Uy, AL1
Olson, SW1
Cushner, HM1
Yuan, CM1
Silverberg, DS1
Wexler, D1
Iaina, A1
Schwartz, D1
Safarinejad, MR1
Asgari, MA1
Hosseini, SY1
Dadkhah, F1
Nowak, Ł1
Zurowski, D1
Garlicki, J1
Thor, PJ1
Mati, VL1
Freitas, RM1
Melo, AL1
Ferrari, P1
Mallon, D1
Trinder, D1
Olynyk, JK1
Shah, SV1
Gohel, MS1
Davies, AH1
Word, R1
Badri, S1
Dashti-Khavidaki, S1
Lessan-Pezeshki, M1
Abdollahi, M1
Vaizova, OE1
Vengerovsky, AI1
Alifirova, VM1
Lu, D1
Song, H1
Li, Y1
Clarke, J1
Shi, G1
Patole, S1
Vijayakumar, P1
Jog, S1
Biolo, G1
Ciocchi, B1
Bosutti, A1
Situlin, R1
Toigo, G1
Guarnieri, G1
Coleridge Smith, PD1
Michetti, C1
Coimbra, R1
Hoyt, DB1
Loomis, W1
Junger, W1
Wolf, P1
Mohan, PV1
Tarnow-Mordi, W1
Stenson, B1
Brocklehurst, P1
Haque, K1
Cavendish, V1
Cust, A1
Moulder, JE1
Nessler, J1
Skrzypek, A1
Lauterbach, R2
Pawlik, D1
Zembala, M1
Szymura-Oleksiak, J1
Lisowska-Miszczyk, I1
Kowalczyk, D1
Bury, J1
Georges, C1
Lefaix, JL1
Delanian, S1
Whitehouse, MW1
Gothard, L1
Cornes, P1
Earl, J1
Hall, E1
MacLaren, J1
Mortimer, P1
Peacock, J1
Peckitt, C1
Woods, M1
Yarnold, J1
Alekhin, DI1
Fokin, AN1
Trent, JT1
Falabella, A1
Eaglstein, WH1
Kirsner, RS1
Ferreira, SH1
Koshkin, VM2
Iglesias, CP1
Claxton, K1
Buell, C1
Tobinick, E1
Lamp, K1
Marston, W1
Gorbunov, AA1
Zaporozhchenko, BS1
Sage, E1
Mercier, O1
Van den Eyden, F1
de Perrot, M1
Barlier-Mur, AM1
Dartevelle, P1
Eddahibi, S1
Herve, P1
Fadel, E1
Koester, M1
Storck, C1
Zorowka, P1
Zimmerer, T1
Böcker, U1
Wenz, F1
Singer, MV1
Pilla, G1
Ciaponi, A1
Migliavacca, A1
Bonora, C1
Rakhmatov, AB1
Ibragimov, ShI1
Angelkort, B6
Kiesewetter, H1
Accetto, B1
Porter, JM1
Cutler, BS1
Lee, BY1
Reich, T1
Reichle, FA1
Scogin, JT1
Strandness, DE1
Shtok, VN1
Fedorova, NV1
Gadanova, IV1
Passero, S1
Nardini, M1
Battistini, N1
Yawalkar, N1
Hunziker, T1
Braathen, LR1
Marci, M1
Albiani, B1
Ricci, M1
Russo, F1
Eninia, GI1
Purinia, IV1
Timofeeva, TN1
Aronoff, SC1
Quinn, FJ1
Carpenter, LS1
Novick, WJ1
Damirov, MM1
Kulakov, VI1
Bakuleva, LP1
Shabanov, AM1
Sarkisov, SE1
Sliusar', NN1
España, A1
Sánchez-Yus, E1
Serna, MJ1
Redondo, P1
Robledo, A1
Quintanilla, E1
Johnson, WC1
Watkins, MT1
Hamilton, J1
Baldwin, D1
Walker, N1
Ramani, A1
Kundaje, GN1
Nayak, MN1
Bogdanets, LI1
Makarova, LD1
Shumskiĭ, AV1
Bauditz, J1
Haemling, J1
Ortner, M1
Lochs, H1
Raedler, A1
Schreiber, S1
Shor, NA1
Helunenko, AM1
Petrunia, AM1
Zelenyĭ, II1
Franks, PJ1
Bosanquet, N1
Brown, D1
Straub, J1
Harper, DR1
Ruckley, CV1
Turner, J1
Frank, AA1
Brooks, JV1
Marietta, PM1
Orme, IM1
Raetsch, C1
Jia, JD1
Boigk, G1
Bauer, M1
Hahn, EG1
Riecken, EO1
Schuppan, D1
Koczorek, M1
Schulz, CE1
Richter, W1
Naujoks, J1
Harwart, D1
Koppenhagen, K1
Wenig, HG1
Gerzić, Z1
Dukić, V1
Milicević, M1
Doppelfeld, E1
Störmer, B1
Kleinschmidt, K1
Loose, D1
Kremer, K1
Blume, J1
Rùhlmann, KU1
de la Haye, R1
Rettig, K1
Wahba-Yahav, AV2
Rumiantsev, ISh1
Kaznacheeva, IG1
Abdiadilova, LV1
Kozlov, VV1
Ernst, E1
Saradeth, T1
Barbarino, C1
Brenman, SA1
Frost, ML1
Treadwell, P1
Petrova, GA1
Levin, GIa1
Crowder, JE1
Cohn, JB1
Savitsky, JP1
Morgan, DL1
Slywka, J1
Cobert, BL1
Hryniewicki, SW1
Piccirillo, RT1
Wilcox, CS1
Trübestein, G1
von Bary, S1
Breddin, K1
Diehm, C1
Gruss, JD1
Heinrich, H1
Horsch, S1
Kriessmann, A1
Maass, U1
Martin, M1
Tesi, M1
Bronchi, GF1
Carini, A1
Karavassili, M1
Nazarova, KhI1
Hartmann, A1
Tsuda, Y1
Vakhrushev, IaM1
Trusov, VV1
Solov'eva, NE1
Ehrly, AM1
Saeger-Lorenz, K1
Shoĭkhet, IN1
Treĭvish, VS1
Novikova, NN1
Spürk, P1
Habbaba, A1
Mähder, M1
Atroshchenko, ES1
Dvorkin, SB1
Chernookiĭ, GP1
Nuzov, BG1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pentoxifylline and Progression of Chronic Kidney Disease in Moderate-to-high Risk Patients: a Pilot Randomized, Placebo-controlled, Double-blind Trial.[NCT00285298]Phase 339 participants (Actual)Interventional2006-01-31Completed
Impact of Pentoxifylline Administration on the Modulation of Hyporesponsiveness to Erythropoietin Stimulating Agents in Hemodialysis Patients[NCT03800433]Early Phase 146 participants (Anticipated)Interventional2019-10-31Not yet recruiting
Is Hepcidin a Possible Contributor to Impaired Iron Mobilization and Anaemia in Hepatitis C Patients Treated With Pegylated Interferon Alpha and Ribavirin Therapy? A Pilot Study[NCT01726400]15 participants (Actual)Observational2012-12-31Completed
Double-Blind, Placebo-Controlled, Randomised Trial Of Alpha-Tocopherol And Oxpentifylline In Patients With Radiation Fibrosis[NCT00022204]Phase 20 participants Interventional2000-01-31Completed
Development of Radiation Fibrosis in Patients Treated With Pentoxyphylline and Vitamin E: a Prospective Randomized Study[NCT00583700]Phase 254 participants (Actual)Interventional2003-02-28Completed
Non-invasive Measurement of Microvascular Blood Flow During Mild External Compression of the Leg[NCT01804478]20 participants (Actual)Interventional2005-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Subjective, Objective, Management, and Analytic (SOMA) Score

A primary outcome of interest is the composite Subjective, Objective, Management, and Analytic (SOMA) score at 18-month follow-up visit. Maximum score is 45, with a score of 0 being ideal and representing no treatment-related side effects at the study visit. (NCT00583700)
Timeframe: 18 month post-treatment

Interventionunits on a scale (Mean)
Control Arm1.59
Intervention: Pentoxifylline & Vitamin E1.0

Tissue Compliance

"Tissue compliance meter measurements of the treated breast compared to the non-treated breast were obtained at 18 months post-radiation therapy. Tissue compliance simply means how soft and pliable the breast tissue is when force is applied to it.~One physician would hold the tissue compliance meter (TCM) against the participant's skin. A standard amount of force would be applied. A second physician would read the displacement scale for a specific set of areas on the breast. The range of the scale was 0 to 60 milimeters (mm). The physician's were blineded to the participant's intervention at the time of measurement.~The final value is the difference between the untreated and the treated breast [untreated - treated]. The range of these differences was -3.3 to 7.0 mm." (NCT00583700)
Timeframe: 18 months post-treatment

Interventionmilimeters (mm) (Mean)
Control Arm2.10
Intervention: Pentoxifylline & Vitamin E0.88

Reviews

22 reviews available for pentoxifylline and Chronic Disease

ArticleYear
[Pentoxifylline old drug or new hope for nephrology?].
    Przeglad lekarski, 2008, Volume: 65, Issue:7-8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Chronic Disease; Cytokines; Humans; Kidney Diseases; Pento

2008
Immunological mechanisms of pentoxifylline in chronic heart failure.
    European journal of heart failure, 2009, Volume: 11, Issue:2

    Topics: Chronic Disease; Heart Failure; Humans; Immunologic Factors; Pentoxifylline; Phosphodiesterase Inhib

2009
Progress toward novel treatments for chronic kidney disease.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2010, Volume: 20, Issue:5 Suppl

    Topics: Amides; Anticoagulants; Antihypertensive Agents; Bicarbonates; Chronic Disease; Enzyme Inhibitors; F

2010
Pharmacological treatment in patients with C4, C5 and C6 venous disease.
    Phlebology, 2010, Volume: 25 Suppl 1

    Topics: Calcium Dobesilate; Cardiology; Chronic Disease; Compression Bandages; Drug Therapy; Flavonoids; Hum

2010
Medical and surgical therapy for advanced chronic venous insufficiency.
    The Surgical clinics of North America, 2010, Volume: 90, Issue:6

    Topics: Bandages; Chronic Disease; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Leg

2010
A review of the potential benefits of pentoxifylline in diabetic and non-diabetic proteinuria.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2011, Volume: 14, Issue:1

    Topics: Animals; Chronic Disease; Diabetic Nephropathies; Disease Progression; Humans; Kidney Diseases; Kidn

2011
Pentoxifylline for endometriosis.
    The Cochrane database of systematic reviews, 2012, Jan-18, Volume: 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Endometriosis; Female; Humans; Immunologic

2012
Perinatal immunomodulation.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2002, Volume: 11, Issue:5

    Topics: Adjuvants, Immunologic; Chronic Disease; Cromolyn Sodium; Female; Glucocorticoids; Hematopoietic Cel

2002
Deleterious effects of white cells in the course of skin damage in CVI.
    International angiology : a journal of the International Union of Angiology, 2002, Volume: 21, Issue:2 Suppl 1

    Topics: Alprostadil; Cell Adhesion Molecules; Chronic Disease; Humans; Iloprost; Leg Ulcer; Leukocytes; Neut

2002
Can polyclonal intravenous immunoglobulin limit cytokine mediated cerebral damage and chronic lung disease in preterm infants?
    Archives of disease in childhood. Fetal and neonatal edition, 2004, Volume: 89, Issue:1

    Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents; Brain Diseases; Chronic Disease; Cytokines; Humans

2004
Post-irradiation approaches to treatment of radiation injuries in the context of radiological terrorism and radiation accidents: a review.
    International journal of radiation biology, 2004, Volume: 80, Issue:1

    Topics: Abnormalities, Radiation-Induced; Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; A

2004
[The modern view on the role of inflammatory factors in chronic heart failure and possibilities of pharmacological modification].
    Przeglad lekarski, 2003, Volume: 60, Issue:6

    Topics: Adrenergic beta-Antagonists; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory

2003
Pentoxyfylline in and prevention and treatment of chronic lung disease.
    Acta paediatrica (Oslo, Norway : 1992). Supplement, 2004, Volume: 93, Issue:444

    Topics: Chronic Disease; Enzyme Inhibitors; Humans; Infant, Newborn; Lung Diseases; Pentoxifylline; Randomiz

2004
Venous ulcers: pathophysiology and treatment options.
    Ostomy/wound management, 2005, Volume: 51, Issue:5

    Topics: Anti-Inflammatory Agents; Aspirin; Bandages; Chronic Disease; Debridement; Diosmin; Growth Substance

2005
[The use of pentoxyphylline in the treatment of patients with chronic obliterative diseases of lower limb arteries].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2005, Volume: 11, Issue:4

    Topics: Administration, Oral; Arterial Occlusive Diseases; Blood Cells; Chronic Disease; Controlled Clinical

2005
Evaluation and treatment of leg ulcers associated with chronic venous insufficiency.
    Clinics in plastic surgery, 2007, Volume: 34, Issue:4

    Topics: Chronic Disease; Humans; Laser Therapy; Leg Ulcer; Pentoxifylline; Stockings, Compression; Vasodilat

2007
[Tinnitus--classification, causes, diagnosis, treatment and prognosis].
    MMW Fortschritte der Medizin, 2004, Jan-15, Volume: 146, Issue:1-2

    Topics: Acute Disease; Adaptation, Physiological; Administration, Oral; Anti-Inflammatory Agents; Audiometry

2004
Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review.
    Zeitschrift fur Gastroenterologie, 2008, Volume: 46, Issue:5

    Topics: Abdominal Neoplasms; Acute Disease; Chronic Disease; Combined Modality Therapy; Controlled Clinical

2008
[Treatment of chronic obliterative arteriopathy of the legs in the second Fontaine's stage. Personal experience with a buflomedil-pentoxifylline-defibrotide combination].
    La Clinica terapeutica, 1995, Volume: 146, Issue:3

    Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Chronic Disease; Drug Therapy, Combination; Fe

1995
[Conservative therapy of chronic venous insufficiency].
    Wiener medizinische Wochenschrift (1946), 1992, Volume: 142, Issue:1

    Topics: Bandages; Chronic Disease; Combined Modality Therapy; Fibrinolytic Agents; Humans; Life Style; Pento

1992
Pentoxifylline as adjunctive therapy in leg ulcer management.
    The Journal of the American Osteopathic Association, 1991, Volume: 91, Issue:7

    Topics: Adjuvants, Pharmaceutic; Adult; Aged; Aged, 80 and over; Blood Cells; Chronic Disease; Female; Human

1991
[Blood rheology in peripheral occlusive disease. Effects of hemodilution and pentoxifylline].
    Wiener medizinische Wochenschrift (1946), 1986, Volume: 136 Spec No

    Topics: Arterial Occlusive Diseases; Chronic Disease; Combined Modality Therapy; Hemodilution; Humans; Pento

1986

Trials

23 trials available for pentoxifylline and Chronic Disease

ArticleYear
Ginkgo biloba extract EGb 761
    International journal of clinical pharmacy, 2018, Volume: 40, Issue:5

    Topics: Adult; Aged; Chronic Disease; Czech Republic; Double-Blind Method; Female; Ginkgo biloba; Humans; Ma

2018
Effect of pentoxifylline in addition to losartan on proteinuria and GFR in CKD: a 12-month randomized trial.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2008, Volume: 52, Issue:3

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Blood Glucose; Blood Pressure; Chemokine CCL2;

2008
Effect of pentoxifylline on GFR decline in CKD: a pilot, double-blind, randomized, placebo-controlled trial.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 53, Issue:4

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Chronic Dis

2009
A double-blind placebo-controlled study of the efficacy and safety of pentoxifylline in early chronic Peyronie's disease.
    BJU international, 2010, Volume: 106, Issue:2

    Topics: Adult; Chronic Disease; Coitus; Delayed-Action Preparations; Double-Blind Method; Humans; Male; Midd

2010
Pentoxifylline improves haemoglobin and interleukin-6 levels in chronic kidney disease.
    Nephrology (Carlton, Vic.), 2010, Volume: 15, Issue:3

    Topics: Anemia, Iron-Deficiency; Biomarkers; Chronic Disease; Ferritins; Hematinics; Hemoglobins; Humans; In

2010
Pentoxifylline improves haemoglobin and interleukin-6 levels in chronic kidney disease.
    Nephrology (Carlton, Vic.), 2010, Volume: 15, Issue:3

    Topics: Anemia, Iron-Deficiency; Biomarkers; Chronic Disease; Ferritins; Hematinics; Hemoglobins; Humans; In

2010
Pentoxifylline improves haemoglobin and interleukin-6 levels in chronic kidney disease.
    Nephrology (Carlton, Vic.), 2010, Volume: 15, Issue:3

    Topics: Anemia, Iron-Deficiency; Biomarkers; Chronic Disease; Ferritins; Hematinics; Hemoglobins; Humans; In

2010
Pentoxifylline improves haemoglobin and interleukin-6 levels in chronic kidney disease.
    Nephrology (Carlton, Vic.), 2010, Volume: 15, Issue:3

    Topics: Anemia, Iron-Deficiency; Biomarkers; Chronic Disease; Ferritins; Hematinics; Hemoglobins; Humans; In

2010
Double-blind placebo-controlled randomised trial of vitamin E and pentoxifylline in patients with chronic arm lymphoedema and fibrosis after surgery and radiotherapy for breast cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2004, Volume: 73, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chronic Disease; Combined Modality Therapy; Confid

2004
Double-blind placebo-controlled randomised trial of vitamin E and pentoxifylline in patients with chronic arm lymphoedema and fibrosis after surgery and radiotherapy for breast cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2004, Volume: 73, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chronic Disease; Combined Modality Therapy; Confid

2004
Double-blind placebo-controlled randomised trial of vitamin E and pentoxifylline in patients with chronic arm lymphoedema and fibrosis after surgery and radiotherapy for breast cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2004, Volume: 73, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chronic Disease; Combined Modality Therapy; Confid

2004
Double-blind placebo-controlled randomised trial of vitamin E and pentoxifylline in patients with chronic arm lymphoedema and fibrosis after surgery and radiotherapy for breast cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2004, Volume: 73, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chronic Disease; Combined Modality Therapy; Confid

2004
Beneficial hemorheologic therapy of chronic peripheral arterial disorders with pentoxifylline: results of double-blind study versus vasodilator-nylidrin.
    American heart journal, 1982, Volume: 103, Issue:5

    Topics: Adult; Aged; Arterial Occlusive Diseases; Chronic Disease; Clinical Trials as Topic; Double-Blind Me

1982
Pentoxifylline efficacy in the treatment of intermittent claudication: multicenter controlled double-blind trial with objective assessment of chronic occlusive arterial disease patients.
    American heart journal, 1982, Volume: 104, Issue:1

    Topics: Aged; Arterial Occlusive Diseases; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; E

1982
Oral pentoxifylline is not effective in the treatment of recalcitrant chronic hand eczema.
    Journal of the American Academy of Dermatology, 1995, Volume: 33, Issue:1

    Topics: Administration, Oral; Chronic Disease; Eczema; Humans; Pentoxifylline; Pilot Projects; Treatment Fai

1995
Intravenous pentoxifylline for the treatment of chronic critical limb ischaemia. The European Study Group.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 1995, Volume: 9, Issue:4

    Topics: Aged; Analgesics; Chronic Disease; Double-Blind Method; Female; Humans; Infusions, Intravenous; Isch

1995
Effects of pentoxifylline on sputum neutrophil elastase and pulmonary function in patients with cystic fibrosis: preliminary observations.
    The Journal of pediatrics, 1994, Volume: 125, Issue:6 Pt 1

    Topics: Administration, Oral; Adolescent; Adult; Bronchitis; Bronchoalveolar Lavage Fluid; Child; Chronic Di

1994
Treatment with tumour necrosis factor inhibitor oxpentifylline does not improve corticosteroid dependent chronic active Crohn's disease.
    Gut, 1997, Volume: 40, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Cells, Cultured; Chronic Disease; Crohn Disease; Drug Therapy, Comb

1997
Perceived health in a randomised trial of treatment for chronic venous ulceration.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 1999, Volume: 17, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Bandages; Chronic Disease; Female; Health Status; Humans; Male; Midd

1999
The treatment of chronic cerebrovascular insufficiency. A double-blind study with pentoxifylline ('Trental' 400).
    Current medical research and opinion, 1979, Volume: 6, Issue:2

    Topics: Administration, Oral; Aged; Cerebrovascular Disorders; Chronic Disease; Clinical Trials as Topic; Do

1979
[The effect of pentoxifylline on liver perfusion: a comparative study in patients with liver diseases and in normal subjects, using 198Au-colloid-scintigraphy (author's transl)].
    Medizinische Klinik, 1979, Aug-31, Volume: 74, Issue:35

    Topics: Adult; Aged; Chronic Disease; Female; Hepatitis; Humans; Liver; Liver Circulation; Liver Cirrhosis;

1979
Treatment of chronic cerebrovascular disease in elderly patients with pentoxifylline.
    Journal of medicine, 1992, Volume: 23, Issue:6

    Topics: Aged; Cerebrovascular Disorders; Chronic Disease; Double-Blind Method; Female; Humans; Male; Middle

1992
Pentoxifylline in the treatment of venous leg ulcers.
    Current medical research and opinion, 1992, Volume: 12, Issue:9

    Topics: Aged; Bandages; Chemotherapy, Adjuvant; Chronic Disease; Double-Blind Method; Female; Humans; Leg Ul

1992
Efficacy and safety of pentoxifylline in geriatric patients with intermittent claudication.
    Angiology, 1989, Volume: 40, Issue:9

    Topics: Aged; Arterial Occlusive Diseases; Blood Pressure; Chronic Disease; Clinical Trials as Topic; Electr

1989
Intravenous prostaglandin E1 versus pentoxifylline therapy in chronic arterial occlusive disease--a controlled randomised multicenter study.
    VASA. Supplementum, 1989, Volume: 28

    Topics: Aged; Alprostadil; Arterial Occlusive Diseases; Chronic Disease; Follow-Up Studies; Humans; Multicen

1989
Therapy of atherosclerotic arteriopathy of lower limbs. Aspects and results.
    Angiology, 1985, Volume: 36, Issue:10

    Topics: Acute Disease; Arteriosclerosis; Chronic Disease; Clinical Trials as Topic; Glycosaminoglycans; Hepa

1985
A controlled study on the effect of pentoxifylline and an ergot alkaloid derivative on regional cerebral blood flow in patients with chronic cerebrovascular disease.
    Angiology, 1988, Volume: 39, Issue:5

    Topics: Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Clinical Trials as Topic; E

1988
Influence of pentoxifylline on muscle tissue oxygen tension (pO2) of patients with intermittent claudication before and after pedal ergometer exercise.
    Angiology, 1987, Volume: 38, Issue:2 Pt 1

    Topics: Arterial Occlusive Diseases; Chronic Disease; Clinical Trials as Topic; Exercise Test; Humans; Inter

1987
Blood flow properties and walking performance in chronic arterial occlusive disease.
    Angiology, 1985, Volume: 36, Issue:5

    Topics: Aged; Arterial Occlusive Diseases; Blood; Blood Circulation; Blood Viscosity; Chronic Disease; Clini

1985

Other Studies

53 other studies available for pentoxifylline and Chronic Disease

ArticleYear
Improvement of Ulcerations in Treatment-Resistant Chronic Scarring in a Patient with Pyoderma Gangrenosum After Improving Vascular Insufficiency, Gently Removing Necrotic Debris, and Decreasing Wound Fluid.
    The American journal of case reports, 2018, Jul-19, Volume: 19

    Topics: Adult; Anti-Infective Agents, Local; Anti-Inflammatory Agents; Chronic Disease; Cicatrix; Clobetasol

2018
Pentoxifylline ameliorates chronic stress/high-fat diet-induced vascular wall disease: the role of circulating endothelial progenitor cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 2019, Volume: 392, Issue:6

    Topics: AC133 Antigen; Animals; Aorta, Thoracic; Body Weight; Chronic Disease; Diet, High-Fat; Endothelial P

2019
Multimodal therapy for chronic tinnitus.
    The international tinnitus journal, 2008, Volume: 14, Issue:1

    Topics: Adult; Aged; Betahistine; Chronic Disease; Cinnarizine; Combined Modality Therapy; Dimenhydrinate; D

2008
Inflammation in chronic heart failure: what is familiar, what is unfamiliar?
    European journal of heart failure, 2009, Volume: 11, Issue:2

    Topics: Anti-Inflammatory Agents; Chronic Disease; Heart Failure; Humans; Inflammation; Pentoxifylline; Tumo

2009
Immunological mechanisms of pentoxifylline in chronic heart failure.
    European journal of heart failure, 2009, Volume: 11, Issue:7

    Topics: Anemia; Biomarkers; Chronic Disease; Heart Failure; Hemoglobins; Humans; Immunologic Factors; Pentox

2009
[Role of pendoxifiline (PTX) in different and cute and chronic models of pain in rats].
    Folia medica Cracoviensia, 2008, Volume: 49, Issue:3-4

    Topics: Acute Disease; Animals; Chronic Disease; Cytokines; Dose-Response Relationship, Drug; Inflammation;

2008
Effects of pentoxifylline during Schistosoma mansoni infection in Swiss mice: an analysis of worm burden, fecundity and liver histopathology.
    Journal of helminthology, 2010, Volume: 84, Issue:4

    Topics: Acute Disease; Animals; Chronic Disease; Female; Fertility; Granuloma; Liver; Male; Mice; Parasite E

2010
[Intravenous laser irradiation of blood for the combined treatment of patients presenting with chronic sensorineural hearing loss].
    Vestnik otorinolaringologii, 2011, Issue:2

    Topics: Adult; Audiometry; Blood; Chronic Disease; Female; Hearing; Hearing Loss, Sensorineural; Humans; Inj

2011
[Endothelium-protective effects of vinpocetine, pentoxifylline and enalapril in patients with chronic brain ischemia].
    Eksperimental'naia i klinicheskaia farmakologiia, 2011, Volume: 74, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Brain Ischemia; Case-Control Studies; Cerebrovascular Circulat

2011
Pentoxifylline acutely reduces protein catabolism in chronically uremic patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002, Volume: 40, Issue:6

    Topics: Amino Acids; Carbon Dioxide; Carbon Isotopes; Chronic Disease; Drug Administration Schedule; Female;

2002
Pentoxifylline reduces acute lung injury in chronic endotoxemia.
    The Journal of surgical research, 2003, Volume: 115, Issue:1

    Topics: Animals; Bronchoalveolar Lavage Fluid; CD11b Antigen; Chronic Disease; Edema; Endotoxemia; Intercell

2003
Case report: resolution of symptomatic epidural fibrosis following treatment with combined pentoxifylline-tocopherol.
    The British journal of radiology, 2004, Volume: 77, Issue:922

    Topics: Adult; Antioxidants; Chronic Disease; Drug Therapy, Combination; Fibrosis; Humans; Intervertebral Di

2004
Anti-TNF-alpha therapy for chronic inflammation: reconsidering pentoxifylline as an alternative to therapeutic protein drugs.
    Inflammopharmacology, 2004, Volume: 12, Issue:3

    Topics: Animals; Chronic Disease; Humans; Inflammation; Lipids; Pentoxifylline; Rats; Tumor Necrosis Factor-

2004
[A new method of treatment of chronic ischemia of extremities with the primary lesion of the distal arterial bed (experimental-clinical investigation)].
    Vestnik khirurgii imeni I. I. Grekova, 2004, Volume: 163, Issue:4

    Topics: Aged; Animals; Anti-Bacterial Agents; Anticoagulants; Arteriosclerosis; Catheterization; Chronic Dis

2004
Proposal to use pentoxifylline and Lyprinol therapy for chronic inflammatory diseases.
    Inflammopharmacology, 2005, Volume: 13, Issue:5-6

    Topics: Chronic Disease; Drug Therapy, Combination; Humans; Inflammation; Lipids; Pentoxifylline; Tumor Necr

2005
Comprehensive decision-analytic model and Bayesian value-of-information analysis: pentoxifylline in the treatment of chronic venous leg ulcers.
    PharmacoEconomics, 2006, Volume: 24, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Bayes Theorem; Chronic Disease; Cost-Benefit Analysis

2006
Resolution of chronic pain and fingertip ulceration due to hand-arm vibration syndrome following combination pharmacotherapy.
    Archives of dermatology, 2007, Volume: 143, Issue:10

    Topics: Chronic Disease; Drug Therapy, Combination; Hand-Arm Vibration Syndrome; Humans; Male; Middle Aged;

2007
[The change of the patients organism immune reactivity in complicated chronic pancreatitis while performance of complex treatment].
    Klinichna khirurhiia, 2007, Issue:7

    Topics: Adult; Antigens, CD; Chronic Disease; Combined Modality Therapy; Female; Free Radical Scavengers; Hu

2007
Endothelial cell apoptosis in chronically obstructed and reperfused pulmonary artery.
    Respiratory research, 2008, Feb-12, Volume: 9

    Topics: Animals; Apoptosis; Chronic Disease; Disease Models, Animal; Endarterectomy; Endothelial Cells; Free

2008
[Chronic senile cerebrovascular insufficiency. Effects of suloctidil and pentoxifylline on erythrocyte deformability].
    La Ricerca in clinica e in laboratorio, 1983, Volume: 13 Suppl 3

    Topics: Cholesterol; Chronic Disease; Erythrocytes; Humans; Intracranial Arteriosclerosis; Pentoxifylline; P

1983
[Clinical and treatment characteristics of psoriasis patients with carbohydrate metabolic disorders].
    Vestnik dermatologii i venerologii, 1983, Issue:6

    Topics: Adult; Aged; Blood Glucose; Carbohydrates; Chronic Disease; Diabetes Mellitus; Drug Therapy, Combina

1983
Influence of risk factors and coagulation phenomena on the fluidity of blood in chronic arterial occlusive disease.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1981, Volume: 156

    Topics: Adenosine Diphosphate; Arterial Occlusive Diseases; Blood Coagulation; Blood Flow Velocity; Chronic

1981
[Clinical study of the cerebrovascular action of pentoxifylline].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:1

    Topics: Acute Disease; Adult; Arteriosclerosis; Brain Ischemia; Cerebrovascular Disorders; Chronic Disease;

1982
Significance of antithrombotic effect in drug therapy of the chronic arterial occlusive disease.
    La Ricerca in clinica e in laboratorio, 1981, Volume: 11 Suppl 1

    Topics: Adenosine Triphosphate; Arterial Occlusive Diseases; Blood Coagulation Disorders; Chronic Disease; E

1981
Effect of pentoxifylline on cerebral blood flow in patients with chronic cerebrovascular disease.
    The Journal of international medical research, 1981, Volume: 9, Issue:3

    Topics: Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Female; Humans; Male;

1981
[The effect of kavinton, trental, sermion and kurantil on the blood flow rate in individual segments of the cerebral arteries].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1994, Volume: 94, Issue:1

    Topics: Blood Flow Velocity; Cerebral Arteries; Chronic Disease; Dipyridamole; Drug Evaluation; Female; Huma

1994
[The clinical picture, diagnosis and treatment of the corpus-isthmus location of uterine endometriosis interna].
    Akusherstvo i ginekologiia, 1993, Issue:3

    Topics: Adult; Chronic Disease; Drug Therapy, Combination; Endometriosis; Endometrium; Fat Emulsions, Intrav

1993
Chronic balanitis with palisading granuloma: an atypical genital localization of necrobiosis lipoidica responsive to pentoxifylline.
    Dermatology (Basel, Switzerland), 1994, Volume: 188, Issue:3

    Topics: Aged; Aged, 80 and over; Balanitis; Chronic Disease; Diagnosis, Differential; Humans; Male; Necrobio

1994
Pentoxifylline therapy for chronic claudication: are patients dependent on therapy?
    Surgery, 1994, Volume: 115, Issue:6

    Topics: Aged; Chronic Disease; Exercise Test; Follow-Up Studies; Humans; Intermittent Claudication; Pentoxif

1994
Pentoxifylline treatment of persistent pulmonary hypertension of newborn.
    European journal of pediatrics, 1993, Volume: 152, Issue:5

    Topics: Chronic Disease; Humans; Hypertension, Pulmonary; Infant, Newborn; Infant, Premature, Diseases; Pent

1993
Hemorheologic approach in the treatment of diabetic foot ulcers.
    Angiology, 1993, Volume: 44, Issue:8

    Topics: Blood Flow Velocity; Chronic Disease; Diabetes Mellitus; Drug Evaluation; Follow-Up Studies; Foot; F

1993
[Treatment of trophic ulcers of the lower extremities with Trental-400].
    Khirurgiia, 1996, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Chronic Disease; Drug Evaluation; Human

1996
[Lymphotropic therapy with trental in the treatment of chronic herpetic stomatitis].
    Stomatologiia, 1997, Volume: 76, Issue:1

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Antibody Formation; Antiviral Agents; Chronic Disease; Dr

1997
[Disorders of the blood microcirculation in patients with suppurative-necrotic complications in diabetes mellitus and the approaches to their correction].
    Klinichna khirurhiia, 1998, Issue:1

    Topics: Adult; Aged; Chronic Disease; Combined Modality Therapy; Conjunctiva; Diabetes Mellitus, Type 1; Dia

1998
Pentoxifylline treatment of mice with chronic pulmonary tuberculosis accelerates the development of destructive pathology.
    Immunology, 2001, Volume: 102, Issue:2

    Topics: Animals; Chemokine CCL2; Chronic Disease; Disease Progression; Female; Interferon-gamma; Lung; Mice;

2001
Pentoxifylline downregulates profibrogenic cytokines and procollagen I expression in rat secondary biliary fibrosis.
    Gut, 2002, Volume: 50, Issue:2

    Topics: Administration, Oral; Animals; Cholestasis; Chronic Disease; Collagen; Cytokines; DNA Probes; DNA, C

2002
[Chronic liver diseases. The nihilism has gone].
    MMW Fortschritte der Medizin, 2001, Dec-13, Volume: 143, Issue:51-52

    Topics: Amantadine; Antioxidants; Antiviral Agents; Chronic Disease; Dipeptides; Drug Therapy, Combination;

2001
[Viscosity of blood and sensorineural hearing loss (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1977, Volume: 56, Issue:4

    Topics: Acute Disease; Audiometry; Blood Viscosity; Capillaries; Chronic Disease; Erythrocytes; Hearing Diso

1977
[Thrombocytic function, plasmatic blood coagulation and fibrinolysis in chronic arterial occlusive disease. Study with pentoxifilline].
    Die Medizinische Welt, 1979, Aug-24, Volume: 30, Issue:34

    Topics: Adult; Aged; Arterial Occlusive Diseases; Blood Coagulation; Blood Platelets; Chronic Disease; Femal

1979
[Drug therapy of chronic tissue ischemia with improvement of microcirculation].
    Acta chirurgica Iugoslavica, 1978, Volume: 25, Issue:1

    Topics: Adult; Blood Vessel Prosthesis; Chronic Disease; Extremities; Humans; Ischemia; Ischemic Attack, Tra

1978
[Treatment of chronic arterial occlusive disease. Clinical study with a new galenic preparation of Pentoxifyllin (Trental 400) (author's transl)].
    Medizinische Klinik, 1978, May-26, Volume: 73, Issue:21

    Topics: Aged; Arm; Arterial Occlusive Diseases; Blood Flow Velocity; Chronic Disease; Drug Evaluation; Femal

1978
Rheological changes in the blood of patients with chronic arterial occlusive disease after the administration of vasoactive drugs.
    Current medical research and opinion, 1977, Volume: 4, Issue:8

    Topics: Arterial Occlusive Diseases; Bencyclane; Blood Viscosity; Chronic Disease; Cycloheptanes; Humans; Pe

1977
Intractable chronic furunculosis: prevention of recurrences with pentoxifylline.
    Acta dermato-venereologica, 1992, Volume: 72, Issue:6

    Topics: Chronic Disease; Furunculosis; Humans; Male; Middle Aged; Pentoxifylline; Recurrence

1992
[The effect of pathogenetic therapy on the expression of endogenous intoxication in patients with chronic glomerulonephritis].
    Terapevticheskii arkhiv, 1992, Volume: 64, Issue:6

    Topics: Chronic Disease; Cyclophosphamide; Drug Therapy, Combination; Glomerulonephritis; Heparin; Humans; M

1992
Chronic leukocytoclastic vasculitis associated with polycythemia vera: effective control with pentoxifylline.
    Journal of the American Academy of Dermatology, 1992, Volume: 26, Issue:6

    Topics: Chronic Disease; Humans; Leg; Male; Middle Aged; Pentoxifylline; Polycythemia Vera; Vasculitis, Leuk

1992
Treatment of sickle cell leg ulcers with pentoxifylline.
    International journal of dermatology, 1990, Volume: 29, Issue:5

    Topics: Anemia, Sickle Cell; Chronic Disease; Humans; Leg Ulcer; Male; Middle Aged; Pentoxifylline; Recurren

1990
[The blood rheological indices of patients with necrobiosis lipoidica].
    Vestnik dermatologii i venerologii, 1989, Issue:12

    Topics: Adult; Aged; Blood Viscosity; Chronic Disease; Erythrocyte Aggregation; Erythrocyte Deformability; F

1989
[Effect of the long-term prophylactic use of trental on cerebral blood flow in diabetics].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:9

    Topics: Adult; Cerebrovascular Disorders; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Diabet

1988
[Trial of the combined use of trental and solcoseryl in treating patients with chronic pancreatitis].
    Terapevticheskii arkhiv, 1988, Volume: 60, Issue:2

    Topics: Actihaemyl; Adult; Chronic Disease; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male

1988
[Pentoxifylline (Trental) in the treatment of chronic glomerulonephritis].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:8

    Topics: Adolescent; Adult; Chronic Disease; Drug Evaluation; Female; Glomerulonephritis; Humans; Hypertensio

1986
[Effect of a course of pentoxifylline (trental) treatment on microcirculatory and central hemodynamic functions in chronic ischemic heart disease patients].
    Terapevticheskii arkhiv, 1985, Volume: 57, Issue:1

    Topics: Adult; Capillary Permeability; Chronic Disease; Coronary Disease; Hemodynamics; Humans; Leg; Lymph;

1985
[Conservative treatment of trophic leg ulcers with trental].
    Vestnik dermatologii i venerologii, 1985, Issue:4

    Topics: Adult; Aged; Chronic Disease; Drug Evaluation; Female; Humans; Male; Middle Aged; Pentoxifylline; Th

1985
[Use of teonikol and trental in the combined treatment of patients with suppurative surgical infection and concomitant diabetes mellitus].
    Klinicheskaia meditsina, 1985, Volume: 63, Issue:12

    Topics: Chronic Disease; Conjunctiva; Diabetes Mellitus; Drug Therapy, Combination; Female; Hemodynamics; Hu

1985