pentoxifylline has been researched along with Chagas Disease in 5 studies
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, pentoxifylline (PTX), an inhibitor of TNF-alpha was investigated on its action upon splenic necrosis, parasitemia and host survival." | 3.74 | Importance of TNF-alpha in the course of acute infection with Trypanosoma cruzi: influence of its inhibition by pentoxifylline treatment. ( Andrade, SG; Magalhães, Ldos A; Pessina, DH, 2008) |
| "cruzi-induced depression is independent of active or prior CNS inflammation." | 1.38 | Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions. ( de Almeida, LR; de Souza, AS; Lannes-Vieira, J; Moreira, OC; Pereira, IR; Rocha, MS; Silva, AA; Silva, RR; Vilar-Pereira, G, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silva Grijó Farani, P | 1 |
| Iandra da Silva Ferreira, B | 1 |
| Begum, K | 1 |
| Vilar-Pereira, G | 3 |
| Pereira, IR | 2 |
| Fernández-Figueroa, EA | 1 |
| Cardenas-Ovando, RA | 1 |
| Almeida, IC | 1 |
| Roy, S | 1 |
| Lannes-Vieira, J | 3 |
| Moreira, OC | 2 |
| Resende Pereira, I | 1 |
| de Souza Ruivo, LA | 1 |
| Cruz Moreira, O | 1 |
| da Silva, AA | 1 |
| Britto, C | 1 |
| Silva, AA | 1 |
| Silva, RR | 1 |
| de Almeida, LR | 1 |
| de Souza, AS | 1 |
| Rocha, MS | 1 |
| Roggero, E | 1 |
| Piazzon, I | 1 |
| Nepomnaschy, I | 1 |
| Perez, A | 1 |
| Velikovsky, A | 1 |
| Revelli, S | 1 |
| Bottasso, O | 1 |
| Andrade, SG | 1 |
| Magalhães, Ldos A | 1 |
| Pessina, DH | 1 |
5 other studies available for pentoxifylline and Chagas Disease
| Article | Year |
|---|---|
Treatment with benznidazole and pentoxifylline regulates microRNA transcriptomic profile in a murine model of Chagas chronic cardiomyopathy.
Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Disease Models, Animal; Fibrosis; Gene Expression Pr | 2023 |
Combination Chemotherapy with Suboptimal Doses of Benznidazole and Pentoxifylline Sustains Partial Reversion of Experimental Chagas' Heart Disease.
Topics: Animals; Chagas Disease; Female; Flow Cytometry; Heart Diseases; Immunohistochemistry; Mice; Mice, I | 2016 |
Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions.
Topics: Animals; Antidepressive Agents, Second-Generation; Chagas Disease; Depression; Emotions; Exploratory | 2012 |
Thymocyte depletion during acute Trypanosoma cruzi infection in C57BL/6 mice is partly reverted by lipopolysaccharide pretreatment.
Topics: Animals; Antibodies, Monoclonal; Chagas Disease; Flow Cytometry; Heart; Interleukin-10; Interleukin- | 2004 |
Importance of TNF-alpha in the course of acute infection with Trypanosoma cruzi: influence of its inhibition by pentoxifylline treatment.
Topics: Acute Disease; Animals; Chagas Disease; Immunohistochemistry; Mice; Mice, Inbred C3H; Necrosis; Para | 2008 |