Page last updated: 2024-11-02

pentoxifylline and Cerebrovascular Disorders

pentoxifylline has been researched along with Cerebrovascular Disorders in 45 studies

Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.

Research Excerpts

ExcerptRelevanceReference
" It covers firstly the general problems of stroke, dementia and 'common symptoms' of the elderly, and then looks in detail at those compounds which have to date attracted most attention (ergot derivatives, cinnarizine, flunarizine, vincamine, eburnamonine, naftidrofuryl, oxpentifylline, piracetam and citicoline), as well as those which are currently considered investigational (choline and lecithin)."6.15'Cerebroactive' drugs. Clinical pharmacology and therapeutic role in cerebrovascular disorders. ( Spagnoli, A; Tognoni, G, 1983)
"Cilostazol has been associated with spontaneous reports of cardiovascular adverse events and serious bleeding."3.88Safety of cilostazol in peripheral artery disease: a cohort from a primary healthcare electronic database. ( Alzamora, M; Forés, R; Giner-Soriano, M; Heras, A; Marsal, JR; Morros, R; Pera, G; Real, J; Ribes, E; Serna, MC, 2018)
"Patients who have had a recent transient ischemic attack (TIA) are at high risk for subsequent stroke."3.77Epidemiology of and stroke-preventive strategies for atherothromboembolic brain infarction in the elderly. ( Adams, HP; Gordon, DL, 1991)
"Pentoxifylline was administered intravenously in a dose of 600 mg daily for 5 days, together with oral aspirin 150 mg daily."2.67Pentoxifylline in the treatment of acute ischaemic stroke--a reappraisal in Chinese stroke patients. ( Chan, YW; Kay, CS, 1993)
" Treatment lasted 7 to 8 weeks with a dosage of 1 tablet 3 times a day."2.64[Treatment of chronic arterial circulatory disorders. Double blind trial with Trental 400 (author's transl)]. ( Kellner, H, 1976)
"Pentoxifylline is a drug known to increase red cell deformability, thus allowing the 7- to 8-micrometers diameter red cell to flow through the narrowest capillaries of 3-5 micrometers diameter."2.36Pentoxifylline and cerebrovascular diseases. ( George, C; Marcel, GA, 1983)
"Musical hallucinations are a kind of auditory hallucination that are prevalent among the non-psychiatric population, but which have rarely been reported in the neurological literature."1.40[Musical hallucinations: perpetual music]. ( Zabalza-Estévez, RJ, 2014)
"Thus, ischemic cerebral edema appears to contribute heavily to morbidity and mortality in stroke."1.26Cerebral edema in stroke: a common, often fatal complication. ( Easton, JD; Sherman, DG, 1980)
"Pentoxifylline was administered orally at a dose of 1200 mg/day over a period of 30 days (eight patients) or by intravenous infusion of 100 ml saline containing 400 mg of the drug in 1 hour (three patients)."1.26Effect of pentoxifylline on cerebral blood flow in patients with chronic cerebrovascular disease. ( Battistini, N; Nardini, M; Passero, S, 1981)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199033 (73.33)18.7374
1990's10 (22.22)18.2507
2000's0 (0.00)29.6817
2010's2 (4.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Real, J1
Serna, MC1
Giner-Soriano, M1
Forés, R1
Pera, G1
Ribes, E1
Alzamora, M1
Marsal, JR1
Heras, A1
Morros, R1
Zabalza-Estévez, RJ1
Agostoni, A1
Martin, P1
Vives, P1
Spagnoli, A1
Tognoni, G1
Hartmann, A4
Beyreder, J1
Lechner, H4
Ott, E5
Bertha, G1
Marcel, GA1
George, C1
Sherman, DG1
Easton, JD1
Fazekas, F1
Emeriau, JP1
Deguilhem, M1
Borde, C1
Raynal, F1
Manciet, G1
Lorient, MF1
Boisseau, MR1
Galley, P1
Müller, R2
Lehrach, F2
Shtok, VN1
Fedorova, NV1
Gadanova, IV1
Passero, S1
Nardini, M1
Battistini, N1
Chan, YW1
Kay, CS1
Gara, II1
Frampton, JE1
Brogden, RN1
Drozdov, SA1
Harwart, D1
Ueda, N1
Muteki, T1
Tajiri, M1
Tayama, F1
Tsutsumi, Y1
Watanabe, H1
Sakanashi, K1
Yoshitake, K1
Tessitore, A1
Barone, A1
Kellner, H1
Koppenhagen, K1
Wenig, HG1
Müller, K1
Theis, H1
Sen, S1
Chakravarty, A1
Ritzmann, D1
Blume, J1
Rùhlmann, KU1
de la Haye, R1
Rettig, K1
Yamamoto, N1
Yokota, K1
Ikegami, A1
Yamashita, A1
Ito, K1
Szobor, A1
Klein, M1
Adams, HP1
Gordon, DL1
Lebedeva, NV2
Khrapova, EV2
Chandra, B1
Bowton, DL1
Stump, DA1
Prough, DS1
Toole, JF1
Lefkowitz, DS1
Coker, L1
Dragunow, M1
Schneider, R1
Nazarova, KhI1
Hsu, CY1
Norris, JW1
Hogan, EL1
Bladin, P1
Dinsdale, HB1
Yatsu, FM1
Earnest, MP1
Scheinberg, P1
Caplan, LR1
Karp, HR1
Tsuda, Y1
Berdichevskiĭ, MIa1
Onopchenko, NV1
Dronnikova, IS1
Eninia, GI1
Egere, DA1
Robule, VKh1
Maĭore, IKh1

Reviews

7 reviews available for pentoxifylline and Cerebrovascular Disorders

ArticleYear
'Cerebroactive' drugs. Clinical pharmacology and therapeutic role in cerebrovascular disorders.
    Drugs, 1983, Volume: 26, Issue:1

    Topics: Adult; Aged; Cerebrovascular Disorders; Cinnarizine; Clinical Trials as Topic; Cytidine Diphosphate

1983
Therapeutical aspects of cerebrovascular disease.
    European neurology, 1983, Volume: 22 Suppl 1

    Topics: Aspirin; Blood Coagulation; Cerebrovascular Disorders; Clofibrate; Dipyridamole; Erythrocyte Aggrega

1983
Pentoxifylline and cerebrovascular diseases.
    European neurology, 1983, Volume: 22 Suppl 1

    Topics: Animals; Blood Viscosity; Brain Edema; Cerebrovascular Circulation; Cerebrovascular Disorders; Dogs;

1983
Haemorheology and cerebrovascular disease: multifunctional approach with pentoxifylline.
    Current medical research and opinion, 1981, Volume: 7, Issue:4

    Topics: Cerebrovascular Circulation; Cerebrovascular Disorders; Edema; Humans; Oxygen Consumption; Pentoxify

1981
Pentoxifylline (oxpentifylline). A review of its therapeutic efficacy in the management of peripheral vascular and cerebrovascular disorders.
    Drugs & aging, 1995, Volume: 7, Issue:6

    Topics: Aged; Cerebrovascular Disorders; Clinical Trials as Topic; Humans; Pentoxifylline; Peripheral Vascul

1995
[Pentoxifylline in the treatment of disorders of the cerebral circulation].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1997, Volume: 97, Issue:9

    Topics: Cerebrovascular Disorders; Humans; Pentoxifylline; Vasodilator Agents

1997
Epidemiology of and stroke-preventive strategies for atherothromboembolic brain infarction in the elderly.
    Clinics in geriatric medicine, 1991, Volume: 7, Issue:3

    Topics: Aged; Anticoagulants; Arteriosclerosis; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Fem

1991

Trials

14 trials available for pentoxifylline and Cerebrovascular Disorders

ArticleYear
'Cerebroactive' drugs. Clinical pharmacology and therapeutic role in cerebrovascular disorders.
    Drugs, 1983, Volume: 26, Issue:1

    Topics: Adult; Aged; Cerebrovascular Disorders; Cinnarizine; Clinical Trials as Topic; Cytidine Diphosphate

1983
Effect of pentoxifylline on regional cerebral blood flow in patients with cerebral vascular disorders.
    European neurology, 1983, Volume: 22 Suppl 1

    Topics: Cerebrovascular Circulation; Cerebrovascular Disorders; Clinical Trials as Topic; Humans; Pentoxifyl

1983
Use of pentoxifylline in the treatment of acute cerebrovascular insufficiency.
    European neurology, 1983, Volume: 22 Suppl 1

    Topics: Acute Disease; Benzamides; Cerebrovascular Disorders; Clinical Trials as Topic; Drug Therapy, Combin

1983
Effect of pentoxifylline on regional cerebral blood flow in patients with cerebrovascular disease.
    Pharmatherapeutica, 1981, Volume: 2, Issue:8

    Topics: Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Female; Humans; Male; Middle Aged; Pen

1981
Pentoxifylline in the treatment of acute ischaemic stroke--a reappraisal in Chinese stroke patients.
    Clinical and experimental neurology, 1993, Volume: 30

    Topics: Acute Disease; Aged; Asian People; Brain Ischemia; Cerebrovascular Disorders; China; Double-Blind Me

1993
The treatment of chronic cerebrovascular insufficiency. A double-blind study with pentoxifylline ('Trental' 400).
    Current medical research and opinion, 1979, Volume: 6, Issue:2

    Topics: Administration, Oral; Aged; Cerebrovascular Disorders; Chronic Disease; Clinical Trials as Topic; Do

1979
[Treatment of chronic arterial circulatory disorders. Double blind trial with Trental 400 (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1976, Oct-22, Volume: 118, Issue:43

    Topics: Administration, Oral; Adult; Aged; Arterial Occlusive Diseases; Cerebrovascular Disorders; Clinical

1976
Clinical experience with pentoxifylline in occlusive cerebrovascular disorders.
    Angiology, 1977, Volume: 28, Issue:5

    Topics: Adult; Cerebrovascular Disorders; Female; Hemiplegia; Humans; Ischemic Attack, Transient; Male; Moto

1977
Treatment of chronic cerebrovascular disease in elderly patients with pentoxifylline.
    Journal of medicine, 1992, Volume: 23, Issue:6

    Topics: Aged; Cerebrovascular Disorders; Chronic Disease; Double-Blind Method; Female; Humans; Male; Middle

1992
Examinations of the relative fluidity in cerebrovascular disease patients.
    Therapia Hungarica (English edition), 1992, Volume: 40, Issue:1

    Topics: Adult; Blood Viscosity; Cerebrovascular Disorders; Ergot Alkaloids; Erythrocyte Indices; Female; Hem

1992
Epidemiology of and stroke-preventive strategies for atherothromboembolic brain infarction in the elderly.
    Clinics in geriatric medicine, 1991, Volume: 7, Issue:3

    Topics: Aged; Anticoagulants; Arteriosclerosis; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Fem

1991
[Use of sermion, Cavinton and trental in patients with cerebrovascular disorders].
    Sovetskaia meditsina, 1990, Issue:1

    Topics: Administration, Oral; Adult; Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Clinical

1990
Pentoxifylline in acute nonhemorrhagic stroke. A randomized, placebo-controlled double-blind trial.
    Stroke, 1988, Volume: 19, Issue:6

    Topics: Acute Disease; Adult; Cerebrovascular Disorders; Clinical Trials as Topic; Double-Blind Method; Huma

1988
A controlled study on the effect of pentoxifylline and an ergot alkaloid derivative on regional cerebral blood flow in patients with chronic cerebrovascular disease.
    Angiology, 1988, Volume: 39, Issue:5

    Topics: Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Clinical Trials as Topic; E

1988

Other Studies

26 other studies available for pentoxifylline and Cerebrovascular Disorders

ArticleYear
Safety of cilostazol in peripheral artery disease: a cohort from a primary healthcare electronic database.
    BMC cardiovascular disorders, 2018, 05-08, Volume: 18, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Cardiovascular Agents; Cerebrovascular Disorders; Cilostazol;

2018
[Musical hallucinations: perpetual music].
    Revista de neurologia, 2014, Mar-01, Volume: 58, Issue:5

    Topics: Aged; Aged, 80 and over; Causality; Cerebrovascular Disorders; Diagnosis, Differential; Female; Hall

2014
[Current status of medical treatment].
    Minerva medica, 1980, Jul-31, Volume: 71, Issue:29

    Topics: Aminophylline; Animals; Anticoagulants; Aspirin; Barbiturates; Brain Ischemia; Cerebrovascular Disor

1980
The effect of pentoxifylline on red cell deformability in cerebrovascular accidents.
    Current medical research and opinion, 1980, Volume: 6, Issue:8

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Capillary Permeability; Cerebrovascular Disorders; Drug Th

1980
Cerebral edema in stroke: a common, often fatal complication.
    Postgraduate medicine, 1980, Volume: 68, Issue:1

    Topics: Adrenal Cortex Hormones; Antioxidants; Barbiturates; Brain Edema; Cerebral Infarction; Cerebrovascul

1980
Hemorheological effects of pentoxifylline on disturbed flow behavior of blood in patients with cerebrovascular insufficiency.
    European neurology, 1983, Volume: 22 Suppl 1

    Topics: Adenosine Diphosphate; Blood Viscosity; Cerebrovascular Disorders; Epinephrine; Erythrocytes; Female

1983
Filterability and cerebro-vascular disease.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1981, Volume: 156

    Topics: Aged; Blood Flow Velocity; Cerebrovascular Disorders; Erythrocyte Membrane; Erythrocytes; Female; Hu

1981
[Clinical study of the cerebrovascular action of pentoxifylline].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:1

    Topics: Acute Disease; Adult; Arteriosclerosis; Brain Ischemia; Cerebrovascular Disorders; Chronic Disease;

1982
Special therapeutical aspects of cerebrovascular disease.
    La Ricerca in clinica e in laboratorio, 1981, Volume: 11 Suppl 1

    Topics: Aspirin; Cerebrovascular Disorders; Drug Combinations; Female; Humans; Male; Pentoxifylline; Platele

1981
Hemorheologic conditions in patients with cerebrovascular disease altered by treatment with pentoxifylline.
    La Ricerca in clinica e in laboratorio, 1981, Volume: 11 Suppl 1

    Topics: Blood Viscosity; Cerebrovascular Disorders; Drug Evaluation; Female; Fibrinogen; Hematocrit; Humans;

1981
Effect of pentoxifylline on cerebral blood flow in patients with chronic cerebrovascular disease.
    The Journal of international medical research, 1981, Volume: 9, Issue:3

    Topics: Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Female; Humans; Male;

1981
[The effect of pentoxifylline and nicergoline on the systemic and cerebral hemodynamics and on the blood rheological properties in patients with an ischemic stroke and atherosclerotic lesions of the major cerebral arteries].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1993, Volume: 93, Issue:3

    Topics: Acute Disease; Adult; Aged; Blood Flow Velocity; Blood Viscosity; Brain Ischemia; Cerebrovascular Di

1993
Clinical evaluation of the effect of pentoxifylline on circulatory behavior of the brain.
    The Kurume medical journal, 1979, Volume: 26, Issue:4

    Topics: Adult; Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Female; Humans; Male; Middle Ag

1979
[Combination of phosphatidylcholine and pentoxifylline in the therapy of progressive obstructive stroke].
    Acta neurologica. Quaderni, 1979, Volume: 39

    Topics: Aged; Blood Viscosity; Cerebrovascular Disorders; Drug Therapy, Combination; Female; Humans; Male; P

1979
Measurement of cerebral blood flow following intravenous administration of pentoxifyline ('Trentral').
    Current medical research and opinion, 1977, Volume: 4, Issue:7

    Topics: Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Female; Humans; Injections, Intravenou

1977
[5 years of clinico-experimental and therapeutic experiences with pentoxifylline].
    Medizinische Monatsschrift, 1977, Volume: 31, Issue:4

    Topics: Arterial Occlusive Diseases; Cerebrovascular Disorders; Chemical Phenomena; Chemistry; Eye Diseases;

1977
[Treatment of cerebrovascular insufficiency symptoms. Experience from practice].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1976, Dec-10, Volume: 52, Issue:34

    Topics: Adult; Aged; Cerebrovascular Disorders; Drug Combinations; Female; Humans; Male; Middle Aged; Neurol

1976
[Hemorheological effect of KB-2796, a new Ca2+ antagonist].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 100, Issue:2

    Topics: Animals; Blood Viscosity; Calcium Channel Blockers; Cerebrovascular Disorders; Erythrocyte Deformabi

1992
Pentoxifylline alters the natural course of acute nonhemorrhagic stroke.
    Stroke, 1990, Volume: 21, Issue:1

    Topics: Acute Disease; Cerebrovascular Disorders; Humans; Nervous System; Pentoxifylline; Theobromine

1990
Pentoxifylline increases cerebral blood flow in patients with cerebrovascular disease.
    Stroke, 1989, Volume: 20, Issue:12

    Topics: Aged; Carbon Dioxide; Cerebrovascular Circulation; Cerebrovascular Disorders; Dose-Response Relation

1989
Possible complications of pentoxifylline in stroke.
    Stroke, 1989, Volume: 20, Issue:8

    Topics: Animals; Cerebrovascular Disorders; Humans; Pentoxifylline; Receptors, Purinergic; Theobromine

1989
[Dynamics of blood serotonin contents in acute disorders of cerebral circulation and circulatory encephalopathy].
    Sovetskaia meditsina, 1989, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Brain Diseases; Cerebrovascular Disorders; Female; Humans; Hypertens

1989
Results of hemorheologically active treatment with pentoxifylline in patients with cerebrovascular disease.
    Angiology, 1989, Volume: 40, Issue:11

    Topics: Blood Pressure; Blood Viscosity; Cerebrovascular Disorders; Erythrocyte Aggregation; Erythrocyte Def

1989
[Effect of the long-term prophylactic use of trental on cerebral blood flow in diabetics].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:9

    Topics: Adult; Cerebrovascular Disorders; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Diabet

1988
[Effect of a series of vasoactive drugs on the compensatory adaptive processes of the brain during acute experimental cerebral venous stasis].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1987, Volume: 87, Issue:8

    Topics: Adaptation, Physiological; Aminophylline; Animals; Brain; Cerebrovascular Disorders; Hydroxyethylrut

1987
[Indications for using trental in the initial manifestations of inadequate blood supply to the brain].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1986, Volume: 86, Issue:1

    Topics: Adult; Blood Coagulation; Blood Viscosity; Cerebrovascular Circulation; Cerebrovascular Disorders; F

1986